目的 探讨TRIB2在结肠癌中的表达水平及与预后及免疫浸润之间的关系。方法 TIMER数据库分析TRIB2在泛癌种中的表达;TCGA、GSE17538下载结肠癌患者RNA-seq数据和临床信息,评估其与临床病理特征的相关性;生存曲线、单因素和多因素Cox分析探讨TRIB2与预后的相关性,并构建列线图;对TRIB2进行差异基因的富集分析;分析TRIB2表达水平与免疫细胞浸润、免疫检查点、肿瘤突变负荷(TMB)以及免疫治疗敏感性之间的相关性。结果 TRIB2在结肠癌组织中高表达(P<0.05);CMS1结肠癌患者TRIB2 mRNA表达水平最高;TRIB2是结肠癌患者的独立预后因素(单因素Cox回归分析:HR=1.397,95%CI:1.100~1.774,P=0.006;多因素Cox回归分析:HR=1.502,95%CI:1.158~1.947,P=0.002);TRIB2与免疫细胞的浸润密切相关,并且与免疫检查点分子表达水平以及TMB正相关(r=0.39,P<0.001);TRIB2的表达水平与免疫检查点抑制剂的疗效相关。结论 TRIB2在结肠癌中高表达且与结肠癌患者预后差和免疫微环境密切相关。
Objective To explore the expression of TRIB2 in colon cancer and its relationship with prognosis and immune cell infiltration.Methods TIMER database was used to analyse the expression of TRIB2 in pan-cancer.RNA-seq data and clinical information of colon cancer patients were downloaded from TCGA and GSE17538 to assess the correlation between TRIB2 with clinicopathological features.Survival curves,univariate and multivariate COX regression analysis were performed to explore the correlation between TRIB2 and prognosis,and a nomogram was constructed.Gene enrichment analyses were performed for TRIB2.Correlations between TRIB2 expression and immune cell infiltration,immune checkpoints,tumor mutation burden(TMB),and immunotherapy sensitivity were analyzed.Results TRIB2 was highly expressed in colon cancer tissues(P<0.05).The highest level of TRIB2 mRNA expression was found in CMS1.TRIB2 was an independent prognostic factor for colon cancer patients(univariate Cox regression analysis:HR=1.397,95%CI:1.100-1.774,P=0.006;multivariate Cox regression analysis:HR=1.502,95%CI:1.158-1.947,P=0.002).TRIB2 was closely associated with immune cell infiltration and positively correlated with the expression level of immune checkpoint molecules as well as TMB(r=0.39,P<0.001).The expression of TRIB2 was correlated with the efficacy of immune checkpoint inhibitors.Conclusions TRIB2 is highly expressed in colon cancer and is closely associated with poor prognosis and the immune microenvironment of colon cancer patients.
目的 分析结核专科医院医学生特征及管理配合度影响因素,为进一步提升医学生管理配合提供参考。方法 选择在院511名医学生进行基本情况采集及问卷调查,以问卷打卡次数及打卡时间评估医学生的管理配合度,并进一步分析其影响因素。结果 进修生、研究生及实习生的性别构成比较差异无统计学意义(P>0.05),而年龄、专业及学历比较差异有统计学意义(P<0.05)。医学生的学历与管理配合度无关,而不同年龄、性别、类别、专业医学生的管理配合度比较差异有统计学意义(P<0.05)。结论 针对结核病专科医院医学生的类别、专业、年龄等不同特征,调整专科医院教学管理方法并实行相应的管理措施,对加强专科教学医院的医学生管理工作具有一定的价值。
Objective To analyze the characteristics and the influencing factors of management cooperation of medical students in tuberculosis specialized hospital,providing reference for further improving the cooperation of medical students in management.Methods Five hundred and eleven medical students were selected in the specialized hospital for basic information collection and questionnaire survey,the management cooperation of medical students were evaluated from the frequency and time of questionnaire check-in,and the influencing factors were further analyzed.Results According to the classification as continuing education students,graduate students and interns,there was no statistical difference in gender,but there were differences in age,major,and education degree(P<0.05).Age,gender,type,and major of the students were all related to management cooperation(P<0.05),while the education degree was not related to it. Conclusions According to the different characteristics of medical students in tuberculosis specialized hospitals,such as their categories,majors and ages,adjusting the teaching management methods in specialized hospitals and implementing management measures have certain reference value for strengthening the management of medical students in specialized teaching hospitals.
目的 探讨免疫及靶向药物联合肝动脉灌注化学治疗(化疗)治疗晚期肝癌的临床疗效。方法 选取甘肃省武威市人民医院2021年1月—2024年1月收治的78例晚期肝癌患者进行回顾性分析,其中20例患者采取单纯肝动脉灌注化疗(HAIC)治疗为单化疗组,30例患者采取HAIC联合程序性细胞死亡受体-1(PD-1)抗体治疗为免疫组,28例患者采取HAIC联合PD-1抗体免疫治疗与甲磺酸仑伐替尼胶囊靶向治疗为联合组。对比三组临床疗效、治疗前后胚抗原(CEA)、糖类抗原125(CA125)、甲胎蛋白(AFP)表达水平,不良反应发生率,并采用Piper疲乏修正量表(PFS-R)、世界卫生组织生存质量量表简表(WHOQOL-BREF)对两组癌因性疲乏程度及生存质量进行评价。结果 单纯化疗组、免疫组、联合组客观缓解率分别为15.00%、40.00%、64.29%,疾病控制率为30.00%、66.67%、82.14%,联合组高于单纯化疗组与免疫组(χ 2 =11.720,P=0.003;χ 2 =13.890,P<0.001);治疗后三组患者CEA、CA125、AFP水平均降低,且联合组[CEA:(13.62±4.24)ng/mL、CA125:(31.62±13.66)U/mL、AFP:(35.21±5.93)ng/mL]低于免疫组[(17.85±3.32)ng/mL、(59.26±9.35)U/mL、(42.12±4.12)ng/mL]及单纯化疗组[(23.73±4.79)ng/mL、(64.57±5.23)U/mL、(47.46±5.32)ng/mL],对比差异有统计学意义(F=7.698,P<0.001;F=11.480,P<0.001;F=14.952,P<0.001;P<0.05);所有患者均无5级不良反应及严重肝功能损害出现,且三组血小板减少、白细胞减少、腹痛、呕吐、消化道出血、厌食等不良反应发生率对比差异无统计学意义(P>0.05);治疗后三组患者PFS-R评分均降低,联合组(3.85±1.13)分低于免疫组(5.39±1.25)分及单纯化疗组(6.33±1.26)分,WHOQOL-BREF评分均升高,联合组(348.58±66.12)分高于免疫组(297.24±72.21)分及单纯化疗组(256.35±41.67)分,对比差异有统计学意义(F=2.526,P=0.014;F=2.167,P=0.033)。结论 免疫及靶向药物联合肝动脉灌注化疗治疗晚期肝癌疗效显著,可有效控制疾病进展的同时,降低机体肿瘤标志物水平,安全性可控,同时可改善患者生存质量,减轻癌因性疲乏程度。
Objective To explore the clinical efficacy of immune and targeted drugs combined with hepatic artery infusion chemotherapy(HAIC)in the treatment of advanced liver cancer.Methods A retrospective analysis was conducted on 78 patients with advanced liver cancer admitted to our hospital from January 2021 to January 2024.Among them,20 patients were treated with simple HAIC and divided into a single chemotherapy group.Thirty patients were treated with HAIC combined with PD-1 antibody,and divided into an immune group.Twenty-eight patients were treated with HAIC combined with PD-1 antibody immunotherapy and lenvatinib mesylate capsule targeted therapy,and divided into a combination group.The clinical efficacy of three groups,the expressionlevels of CEA,CA125,AFP,and incidence of adverse reactions before and after treatment were compared.Piper Fatigue Correction Scale(PFS-R)and the WHO QOL-BREF were used to assess cancer-related fatigue in both groups.The degree of fatigue and quality of life were assessed.Results The objective response rates of the simple chemotherapy group,the immune group,and the combination group were 15.00%,40.00% and 64.29%,respectively.The disease control rates were 30.00%,66.67% and 82.14%,respectively.The indicators above of the combination group was significantly higher than those in the simple chemotherapy group and the immune group(χ 2 =11.720,P=0.003;χ 2 =13.890,P<0.001;P<0.05).After treatment,the levels of CEA,CA125 and AFP were all decreased in the three groups,and those in the combined group (CEA[13.62±4.24]ng/mL,CA125[31.62±13.66]U/mL,AFP:Ng/mL[35.21±5.93])were lower than those in the immune group(17.85±3.32 ng/mL,59.26±9.35 U/mL,/ 42.12±4.12 ng/mL)and single chemotherapy group(23.73±4.79 ng/mL,64.57±5.23 U/mL47.46±5.32]ng/mL),the differences were statistically significant(F=7.698,P<0.001;F=11.480,P<0.001;F=14.952,P<0.001;P<0.05).All patients had no grade 5 adverse reactions or severe liver function damage,and there was no statistically significant difference in the incidence adverse reactions such as thrombocytopenia,leukopenia,abdominal pain,vomiting,gastrointestinal bleeding,and anorexia among the three groups(P>0.05).After treatment,the PFS-R score of the three groups was decreased,and the combined group(3.85±1.13)score was lower than that of the immune group(5.39±1.25)and the chemotherapy group(6.33±1.26).While the WHOQOL-BREF score was increased,the score of combination group(348.58±66.12)was higher than that of immune group(297.24±72.21)and chemotherapy group(256.35±41.67),and the difference was statistically significant(F=2.526,P=0.014;F=2.167,P=0.033;P<0.05).Conclusions The combination of immune and targeted drugs with hepatic artery infusion chemotherapy has a significant therapeutic effect on advanced liver cancer.It can effectively control disease progression,reduce tumor marker levels in the body,improve patient quality of life,and alleviate cancer-related fatigue,with controllable safety
目的 面向采血人群的“智慧服务”是智慧医院构建的重要内容,引进智能采血管理系统有助于采血“智慧服务”的实现。文章介绍了广州市属大型三甲医院应用智能采血管理系统的实践,并对于系统出现的问题进行整理及分析,以找出有效解决对策。方法 将采血系统出现故障后的解决对策改良前后分为对照组和观察组,记录采血过程中出现故障的原因及次数,采血故障解决对策改良后的数据为观察组。结果 观察组相较于对照组各项故障的发生率显著降低。结论 在智慧医院构建背景下引进智能采血系统可有助于实现采血“智慧服务”,但在实施过程中应做好新旧采血方式的衔接并落实问题收集和对策制定。
Objective Intelligent Service for blood collection crowd is an important content of intelligent hospital,the introduction of intelligent blood collection management system is conducive to the implementation of “Intelligent Service” blood collection.This paper introduces the application of Intelligent Blood Collection Management System in Guangzhou first-class Hospital,collectis and analyses common systematic problems,to effectively find out the solutions.Materials and methods The patients were divided into control group and observation group before and after the improvement of the countermeasures after the failure of the blood collection system,the reasons and times of the failure were recorded,and the data after the improvement of the countermeasures were taken as the observation group.Results The incidence of various faults in the observation group was significantly lower than that in the control group.Conclusions The introduction of intelligent blood collection system under the background of the construction of smart hospital can help realize the “intelligent service” of blood collection,but in the implementation process,it is necessary to do a good job in the connection of old and new blood collection methods and implement the problem collection and countermeasures.
目的 评价现有关于干预组仅涉及不同针具针刺或联合常规针刺治疗腰椎间盘突出症系统评价的方法学质量,以比较不同针具针刺治疗腰椎间盘突出症的治疗效果。方法 通过CNKI(中国知网)、万方数据库、VIP(维普)、PubMed、Web of Science等数据库以及其他相关电子资源,对诊断、治疗腰椎间盘突出症的多种针灸技术进行全面的研究。使用AMSTAR2软件,对所有参与的系统性评估结果进行地分析,并根据不同的检测结果,确定文献筛选标准。通过Revman5.4和Cochrance风险偏倚工具,以及Stata16.0的网格Meta分析,挑选了3 381个满足纳入排除要求的随机对照试验。结果 以Stata 16.0统计软件制作排序图可知,杵针+电针的临床有效率SUCRA=81.6%排名第一;目测类比评分显示,银质针SUCRA(用于评估疗效的指标)=95%,排名第一。结论 根据现有的研究证据,杵针+电针以及银质针优于其他9种干预措施,但确切的结果仍需要大量的随机对照试验来证明。
Objective To evaluate the methodological quality of the existing systematic evaluation of the intervention group involving only different needle sets of acupuncture or combined with conventional acupuncture in the treatment of lumbar disc herniation,in order to compare the therapeutic effect of different needle sets of acupuncture in the treatment of lumbar disc herniation.Methods Through CNKI,Wanfang database,VIP,PubMed,web of science and other databases as well as other relevant resources,a variety of acupuncture techniques for the diagnosis and treatment of lumbar disc herniation were comprehensively studied.Through the use of AMSTAR2 software,all participating systematic evaluation results were effectively analyzed,and according to different test results,which literature meets the requirements were determined.Through revman5.4,Cochrane risk bias tool,and grid meta-analysis of stata16.0,3 381 RCTs meeting the inclusion and exclusion requirements were selected.Results According to the ranking chart made by stata16.0 statistical software,the clinical effective rate of pestle needle + electroacupuncture ranked first with sucra=81.6%.According to the visual analogy score,the silver needle sucra=95%,ranking first.Conclusions According to the existing research evidence,pestle needle + electroacupuncture and silver needle are better than the other nine interventions,but the exact results still need a large number of randomized controlled trials to prove.
目的 探讨非肌层浸润性膀胱癌患者初次经尿道膀胱肿瘤电切术的复发情况及危险因素。方法 以93例非肌层浸润性膀胱癌患者进行研究,2018年1月至2022年1月西藏自治区人民政府驻成都办事处医院泌尿外科医院收治采取经尿道膀胱肿瘤电切术,术后随访24个月,复发22例,未复发71例,比较复发与未复发基础情况、不同肿瘤直径、不同肿瘤分期、分级、数量、是否带蒂、灌注化疗方式等特征患者的复发情况,对具有统计学意义的因素,采取非条件Logistic多因素回归分析,明确术后复发的危险因素。结果 肿瘤分期T1期者的复发率为32.08%,高于Ta期者15.50%,肿瘤分级为高级别者的复发率为53.33%,高于低级别者17.95%,肿瘤多发者的复发率为35.71%,高于单发者的13.73%,肿瘤不带蒂者的复发率为38.71%,高于肿瘤带蒂者的16.13%,常规灌注化疗患者的复发率为29.85%,高于术后即刻+灌注化疗患者的7.69%,比较差异均有统计学意义(χ 2 分别为6.648、4.836、6.872、6.166、5.834、5.902,P分别为0.010、0.027、0.008、0.013、0.015、0.024)。肿瘤分期T1期、肿瘤分级为高级别、肿瘤多发、常规灌注化疗为非肌层浸润性膀胱癌行初次经尿道膀胱肿瘤电切术的术后复发的危险因素(P<0.05)。结论 非肌层浸润性膀胱癌患者初次采取经尿道膀胱肿瘤电切术容易因为临床分期为T1期、肿瘤分级为高级别、肿瘤多发及常规灌注等出现复发,应采取针对性干预措施,改进灌注化疗方式,降低复发率。
Objective To investigate the relapse and risk factors of non-muscular invasive bladder cancer after primary transurethral resection.Methods A total of 93 patients with non-muscular invasive bladder cancer were selected for study.They were received by the hospital from January 2018 to January 2022 and underwent transurethral resection.After 24 months of follow-up,22 patients recurred,and 71 patients did not recur.The recurrence of patients with different tumor diameter,tumor stage,grade,numbers,pedicel or not,and infusion chemotherapy methods were compared.For the statistically significant factors,unconditional logistic regression analysis was used to determine the independent risk factors for recurrence.Results The recurrence rate in T1 stage of tumor was 32.08% higher than that in Ta stage,which was 15.50%.The recurrence rate in high stage was 53.33% higher than that in low stage,which was 17.95%.The recurrence rate in multiple tumor patients was 35.71% higher than that in single tumor patients,which was 13.73%.The no-pedicle tumor recurrence rate was 38.71% higher than that with pedicle,which was 16.13%.The recurrence rate in patients receiving conventional infusion chemotherapy was 29.85% higher than that in patients receiving immediate postoperative infusion chemotherapy,which was 7.69%.The differences were statistically significant(χ 2 =6.648、4.836、6.872、6.166、5.834、5.902,P=0.010、0.027、0.008、0.013、0.015、0.024).The independent risk factors of recurrence after primary transurethral resection were tumor stage T1,high grade tumors,multiple tumors,routine perfusion chemotherapy as non-muscular invasive bladder cancer(P<0.05).Conclusions The patients with non-muscular invasive bladder cancer taking transurethral resection for the first time are prone to recurrence because of the clinical stage of T1,tumor grade of high grade,multiple tumors and routine perfusion.Targeted intervention measures should be taken to improve the perfusion chemotherapy method to reduce the recurrence rate.
目的 探究支气管镜联合雾化吸入药物对肺炎支原体肺炎患儿症状持续时间及肺部影像学好转情况。方法 选取94例肺炎支原体肺炎患儿为研究对象,以随机数字表法分为A组、B组,各47例,分别实施布地奈德雾化吸入治疗、支气管镜肺泡灌洗联合布地奈德雾化吸入治疗,比较两组症状持续时间、治疗后肺部影像改善情况、炎症指标水平及不良反应发生率。结果 B组体温恢复时间(2.73±0.51)d、咳嗽消失时间(5.98±1.24)d、住院时间(10.96±3.36)d,A组分别为(3.14±0.83)(7.06±2.33)(13.27±3.18)d,B组较A组短(t=2.885、2.809、3.423,均P<0.05);治疗后B组40.43%阴影完全消失、34.04%阴影显著缩小、23.40%阴影有所缩小、2.13%阴影改善不明显,A组分别为21.28%、36.17%、25.53%、17.02%,B组肺部阴影改善情况优于A组(Z=8.311,P<0.05);治疗前B组白细胞计数(WBC)、超敏C-反应蛋白(hs-CRP)、降钙素原(PCT)水平与A组相近(P>0.05);治疗后B组WBC(7.71±1.94)×109 /L、hs-CRP(4.96±1.44)mg/L、PCT(84.32±21.40)pg/mL,A组分别为(9.05±2.48)×109 /L、(6.17±1.85)mg/L、(105.46±34.02)pg/mL,B组水平较A组低(t=2.918、3.538、3.606,均P<0.05);B组不良反应发生率为8.52%,A组为4.26%,B与A组相近(χ 2 =0.178,P>0.05)。结论 对肺炎支原体肺炎患儿实施支气管镜联合雾化吸入药物治疗,可缩短康复时间,促进肺部阴影消退,降低其炎症指标水平,且未增加不良反应发生率。
Objective To investigate the effect of bronchoscopy combined with nebulized inhalation of medication on the duration of symptoms and pulmonary imaging conversion in children with Mycoplasma pneumoniae pneumonia(MPP).Methods A total of 94 children with MPP were selected as the research subjects and randomly divided into Group A and Group B using a random number table,with 47 cases in each group.They were treated with budesonide nebulization inhalation therapy and bronchoalveolar lavage combined with budesonide nebulization inhalation therapy,respectively.The duration of symptoms,improvement of lung imaging before and after treatment,levels of inflammatory indicators,and incidence of adverse reactions were compared between the two groups.The results showed that the temperature recovery time was(2.73±0.51)days,cough disappearance time was(5.98±1.24)days,and hospitalization time was(10.96±3.36)days in Group B,(3.14±0.83)days,(7.06±2.33)days,and(13.27±3.18)days in Group A,respectively.Durpation in Group B was shorter than Group A(t=2.885,2.809,3.423,all P<0.05). After treatment,40.43% of the shadows in Group B completely disappeared,34.04% of the shadows significantly reduced,23.40% of the shadows reduced,and 2.13% of the shadows showed no significant improvement,better than 21.28%,36.17%,25.53%,and 17.02% in Group A(Z=8.311,P<0.05). Before treatment,the white blood cell count(WBC),high-sensitivity C-reactive protein(hs CRP),and procalcitonin(PCT)levels in group B were similar to those in Group A(P>0.05).After treatment,the WBC(7.71±1.94)×109 /L,hs CRP(4.96±1.44)mg/L,and PCT(84.32±21.40)pg/mL in Group B were lower than those in Group A(9.05±2.48)×109 /L,(6.17±1.85)mg/L,and(105.46±34.02)pg/mL,respectively(t=2.918,3.538,3.606,all P<0.05).The incidence of adverse reactions in Group B was 8.52%,while in Group A it was 4.26%.The incidence of adverse reactions in group B was similar to that in group A(χ 2 =0.178,P>0.05).Conclusions Bronchoscopy combined with nebulized inhalation therapy for children with MPP can shorten the recovery time,promote the disappearance of lung shadows,reduce their inflammatory index levels,and without increasing the incidence of adverse reactions.
目的 分析串联质谱技术筛查高危新生儿遗传代谢性疾病的价值。方法 于2023年1月—2024年3月,选择入住本院新生儿科的995例高危新生儿作为研究对象,采用串联质谱技术进行筛查,对筛查结果进行分析。结果 本研究期内995例新生儿初筛查阳性83例,最终确诊5例,假阳性78例,真阴性912例,阳性率8.34%(83/995),真阳性率6.02%(5/83)。确诊病例包括尿素循环障碍及高氨血症4例(其中2例经全外显子组核心家系测序分析确诊鸟氨酸氨甲酰转移酶缺乏症,基因变异来源为新发),枫糖尿症1例(基因确诊,变异来源为父亲及母亲)。结论 在高危新生儿遗传代谢疾病的筛查中,运用串联质谱技术进行筛查,及时有效进行专项检查,早期诊断遗传代谢性疾病,及时控制病情进展,降低死亡率和致残率,从而提高人口素质及生存质量,同时,对遗传代谢病的高危家庭开展咨询,指导优生优育。
Objective To analyze the value of tandem mass spectrometry in screening genetic metabolic diseases in high-risk neonates.Methods From January 2023 to March 2024,a total of 995 high-risk neonates admitted to the neonatal department of our hospital were selected as the research subjects,tandem mass spectrometry was used for screening,and the screening results were analyzed.Results During the study period,83 of the 995 neonates were positive in the initial screening,5 cases were finally confirmed,78 cases were false positives,and 912 cases were true negatives,with a positive rate of 8.34%(83/995)and a true positive rate of 6.02%(5/83).The confirmed cases included 4 cases of urea cycle disorder and hyperammonemia(2 cases were confirmed with ornithine carbamyltransferase deficiency by whole exome core family sequencing analysis,and the source of the gene variant was de novo),and 1 case of maple syrup urine disease(genetic diagnosis,the source of the mutation was father and mother).Conclusions In the screening of genetic metabolic diseases in high-risk neonates,the use of special examinations in tandem mass spectrometry can timely and effectively diagnosis genetic metabolic diseases,therefore timely control the progression of disease and reduce mortality and disability rates,consequently improve the quality of population and life.At the same time,we can provide guidance for good birth and good parenting by carrying out consultation to high-risk genetic metabolic diseases families.
目的 探析子宫输卵管超声造影(D-HyCoSy)配合宫腔水造影对不孕症患者宫腔粘连(IUA)诊断灵敏度、特异度情况。方法 选取2021年1月—2023年2月南华大学附属长沙中心医院的110例不孕症者为研究对象,均予以宫腔水造影、D-HyCoSy,以宫腔镜病理结果为金标准,分析不同诊断方法应用的效果。结果 在110例不孕症患者中,经宫腔镜病理检查发现,宫腔粘连患者占比47.27%(52/110)。D-HyCoSy的诊断准确率为76.36%、宫腔水造影的为79.09%,均低于联合诊断的93.63%(P<0.05)。D-HyCoSy的诊断灵敏度为73.08%,宫腔水造影的为80.77%,均低于联合诊断的94.23%,差异具有统计学意义(P<0.05)。D-HyCoSy的诊断特异度为79.31%,宫腔水造影的为77.59%,与联合诊断的93.10%相比,差异无统计学意义(P>0.05)。结论 对于不孕症患者,予以宫腔水造影联合D-HyCoSy诊断,其诊断效能高于单一诊断检查率,能更准确地判定宫腔粘连,效能高。
目的 旨在通过实证了解广东省青年中医人才岗位胜任力现状,探讨青年中医人才岗位胜任力素质特征,为青年中医人才培养提供策略。方法 通过专家咨询制定《青年中医人才岗位胜任力评价框架》并开展问卷调查,采用SPSS 26.0进行数据分析。结果 构建了包含8个一级指标、76个二级指标的《青年中医人才岗位胜任力评价框架》;广东省青年中医人才岗位胜任力自评总分整体处于及格以上水平。女性在职业价值和职业素养、临床技能、交流与沟通技能、管理能力和团队合作、批判性思维与学术科研能力的评分高于男性;不同职称在其他附加维度的评分比较具有统计学差异(P<0.05)。结论 构建的评价框架能够有效评估青年中医人才岗位胜任力;广东省青年中医人才岗位胜任力整体处于及格水平,需重视补强短板;女性青年中医人才岗位胜任力多个维度的得分优于男性,着重提升各人群的弱项维度岗位胜任力;进一步建立健全职称评聘制度,以破五唯为导向构建符合不同级别职称的青年中医人才评价机制。
Objective To understand the current job competence status of young TCM talents in Guangdong Province through empirical research,to explore the characteristics of job competence and quality of young TCM talents,providing strategy for cultivating young talents in TCM.Methods The “Competency Evaluation Framework for Young TCM Talents” was developed through expert consultation and a questionnaire survey was conducted.SPSS 26.0 was used for data analysis.Results “Job Competency Evaluation Framework for Young TCM Talents” was constructed,which included 8 primary indicator items and 76 secondary indicator items.The overall self-evaluation score of the overall job competence of young TCM talents in this study was above the passing level.Female score was higher than male in terms of professional value and professional ethics,clinical skills,communication and interpersonal skills,management ability and teamwork,critical thinking and academic research ability.There were statistically significant differences in the scores of different job titles in other additional dimensions(P<0.05).Conclusions The constructed evaluation framework can effectively assess the job competence of young TCM talents.The overall competence of young TCM talents in Guangdong Province is at a passing level,and attention should paid to strengthening their weaknesses.Female young TCM talents have better multidimensional scores in job competence than males,and efforts should be made to focus on improving the weak dimensional job competence of various groups of people.The professional title evaluation and appointment system needs to be established and improved.A talent evaluation mechanism should be built for young TCM talents that meets different levels of professional titles,guided by the principle of breaking the five criteria.