小柴胡汤是《伤寒杂病论》中的一首经典方剂,是和解法的基础方,后世将其广泛用于治疗妇科疾病。本研究旨在通过文献检索,探讨小柴胡汤在治疗妇科疾病方面的有效性及其应用的最新进展。文章综述了小柴胡汤在治疗妇科痛证、血证、带下证、块证等相关疾病方面的临床研究和实践经验。小柴胡汤通过其疏肝利胆、健运脾胃、和解枢机的作用,有效改善了女性痛经、盆腔炎性疾病、月经不调、妇科肿瘤、围绝经期综合征等妇科疾病症状。作为临床常用的妇科学方剂,小柴胡汤亟需进一步的发扬与创新,以期更有效地应用于未来的临床实践。
Xiaochaihu Decoction,as a classic prescription in the Treatise on Cold Pathogenic and Miscellaneous Diseases,laid the foundation for reconciliation.It has a wide range of applications in the treatment of gynecological diseases.Through a literature search,this study aimed to explore the effectiveness of Xiaochaihu Decoction in the treatment of gynecological diseases and the latest progress of its application.This article reviews the clinical research and practical experience of Xiaochaihu Decoction in the treatment of gynecological pain,bleeding,leucorrhea disease,tumors and other related diseases.Xiaochaihu Decoction has effectively improved the symptoms of gynecological diseases such as dysmenorrhea,pelvic inflammatory disease,menstrual irregularities,gynecological tumors,and perimenopausal syndrome through its role of soothing the liver and promoting bile flow,strengthening the spleen and stomach,and harmonizing and releasing the pivot.As a commonly used gynecological prescription in clinical practice,Xiaochaihu Decoction urgently needs to be further developed and innovated to be more effectively applied to clinical practice in the future.
本文概述了传统日间腹腔镜胆囊切除术患者术后早期康复质量存在的问题,IMB模型通过向患者提供科学的疾病知识,改变其疾病认知与态度,最终促使其采纳并维持健康行为。本文还介绍了IMB模型在日间腹腔镜胆囊切除术后患者早期康复质量中应用涉及的相关概念、研究背景和国内外的研究现状以及未来发展趋势与挑战。研究结果显示,IMB模型可显著降低患者术后疼痛发生率,并提高患者参与治疗决策的程度,为后期关于IMB模型在日间腹腔镜胆囊切除术患者术后早期康复质量的相关研究提供借鉴与参考,以便后期实施相关个性化干预措施,并提供相关理论依据。
This paper summarizes the problems existing in the early postoperative rehabilitation quality of patients undergoing traditional ambulatory laparoscopic cholecystectomy.The IMB model changes patients’ disease cognition and attitude by providing them with scientific disease knowledge,and ultimately promotes their adoption and maintenance of healthy behaviors.It also introduces the relevant concepts involved in the application of the IMB model in the early postoperative rehabilitation quality of patients undergoing ambulatory laparoscopic cholecystectomy,the research background of this study,the current research status at home and abroad,as well as the future development trends and challenges.The research results show that the IMB model can significantly reduce the incidence of postoperative severe pain in patients and the degree of patient participation in treatment decision-making.This provides reference and guidance for subsequent studies on the early rehabilitation quality of patients undergoing ambulatory laparoscopic cholecystectomy using the IMB model,so as to implement relevant personalized intervention measures in the future and provide relevant theoretical basis.
药物流产是终止早期妊娠的常用方法,但流产后仍易出现阴道持续出血、不全流产、盆腔感染及月经紊乱等并发症,影响患者生殖健康。生化汤作为中医经典方剂,具有活血化瘀、温经止痛、祛瘀生新之功效,在药物流产后并发症的临床治疗中应用广泛。本文通过梳理近年相关文献,从生化汤概述、药物流产及其并发症、生化汤的临床应用、作用机制及使用禁忌等方面进行系统综述,重点分析现有研究的局限性及争议性问题,并对未来研究方向提出展望,以为临床应用生化汤治疗药物流产后并发症提供理论依据与实践参考。?
巨大/破裂型腰椎间盘突出症(G/RLDH)是腰椎间盘突出症的严重类型,可致剧烈根性疼痛及神经功能障碍。推拿作为非药物中医疗法,广泛应用于腰椎间盘突出症,但治疗G/RLDH的疗效与安全性尚存争议。近年发现G/RLDH具有较高的椎间盘自然重吸收率,为推拿干预提供了病理基础。本文系统检索相关文献,从中医病机、现代医学机制、临床应用及安全性争议等方面进行综述,旨在指导临床诊治并为未来研究提供参考。
Giant/ruptured lumbar disc herniation (G/RLDH) is a severe type of lumbar disc herniation that can cause intense radicular pain and neurological dysfunction. As a non-pharmacological therapy in traditional Chinese medicine, tuina is widely used for lumbar disc herniation; however, its efficacy and safety in treating G/RLDH remain controversial. Recent studies have revealed a relatively high rate of spontaneous resorption of herniated discs in G/RLDH, which provides a pathological basis for tuina intervention. This article systematically reviews the relevant literature, summarizing the traditional Chinese medicine pathogenesis, modern medical mechanisms, clinical application, and safety controversies, aiming to guide clinical diagnosis and treatment and to provide a reference for future research.
虽然高效抗逆转录病毒治疗已经把艾滋病变成了能够长期管理的慢性传染病,可是患者预后的个体差异比较明显。近些年不良环境暴露被发现是影响艾滋病生存质量、免疫重建、疾病进展的重要外源性因素。环境污染物作为广泛存在而且有可预防的外部风险因素,有着低剂量、长时程、多途径暴露的特点,能够通过免疫毒性、氧化应激、慢性炎症激活、代谢紊乱等多种通路,干扰艾滋病患者的免疫重建进程和病毒抑制效果,进而影响其疾病进展、远期生存结局。本文系统综述了大气污染物、重金属、黄曲霉素、多环芳烃等典型环境污染物与艾滋病患者发病进展及预后转归的关联,深入分析人群易感性差异和当前研究存在的局限,可为优化HIV/AIDS患者的健康管理策略、降低环境相关健康风险、改善患者远期预后给予理论参考和实践依据。
Although highly active antiretroviral therapy has turned AIDS into a chronic infectious disease that can be managed for a long time, the individual differences in the prognosis of patients are obvious. In recent years, adverse environmental exposure has been found to be an important exogenous factor affecting the quality of life, immune reconstruction and disease progression of AIDS. As an external risk factor that exists and has potential intervention, environmental pollutants have the characteristics of low-dose, long-term and multi-channel exposure. They can interfere with the immune reconstruction process and virus inhibition effect of AIDS patients through various pathways such as immunotoxicity, oxidative stress, chronic inflammation activation, and metabolic disorders, thereby affecting their disease progression and long-term survival outcomes. This article systematically reviews the association between typical environmental pollutants such as air pollutants, heavy metals, aflatoxins, and polycyclic aromatic hydrocarbons and the progression and prognosis of AIDS patients. In-depth analysis of the differences in population susceptibility and the limitations of current research can provide theoretical reference and practical basis for optimizing the health management strategies of HIV / AIDS patients, reducing environmental-related health risks, and improving the long-term prognosis of patients.
动脉粥样硬化(AS)是心血管疾病的病理基础,口腔与肠道通过菌群移位、代谢互作及免疫联动共同构成口腔-肠道微生物轴,其稳态失衡通过菌群易位、代谢紊乱和屏障损伤等促进AS发生发展。中医药以整体观念与辨证论治为指导,多靶点调控口腔-肠道微生物平衡,抑制血管炎症与脂质沉积,发挥抗AS效应。本文系统阐述口腔-肠道微生物与AS的关联,探讨中医药调控微生态防治该病的研究进展,分析当前研究存在的局限并展望未来方向,为中医药防治AS提供新的思路与理论依据。
Atherosclerosis (AS) is the pathological basis of cardiovascular diseases. The oral cavity and the gut together constitute the oral-gut microbial axis through microbial translocation, metabolic interactions, and immune crosstalk. Dysbiosis of this axis promotes the occurrence and development of AS via bacterial translocation, metabolic disorders, and barrier damage. Guided by the holistic concept and syndrome differentiation-based treatment, traditional Chinese medicine (TCM) exerts anti-AS effects by multi-target regulation of the oral-gut microbial balance, inhibiting vascular inflammation and lipid deposition. This article systematically elaborates the association between the oral-gut microbiota and AS, explores the research progress of TCM in modulating microecology for the prevention and treatment of AS, analyzes the limitations of current studies, and prospects future directions, so as to provide new insights and theoretical basis for TCM in preventing and treating AS.
登革热是由登革病毒引起、经伊蚊叮咬传播的急性传染病,近年来已在全球热带和亚热带地区广泛流行,严重威胁公共卫生安全。目前临床上尚缺乏特异性抗病毒药物和高效的疫苗,临床治疗主要以中西医结合为主要模式,且两者在发病机制阐释、诊疗策略制定等方面各有侧重且互为补充。本文系统梳理登革热西医领域的流行病学特征、病理基础与发病机制及现代医学治疗现状,同时深入阐述中医对该病的病因病机与病位认知、辨证论治体系及中医药治疗进展,旨在为临床诊疗优化与科研方向拓展提供参考。
Dengue fever is an acute infectious disease caused by the dengue virus. In recent years, it has prevailed widely in tropical and subtropical regions, posing a severe threat to public health security. Given the lack of specific antiviral drugs and high-efficiency vaccines for dengue fever, its clinical treatment is predominantly based on integrated traditional Chinese and Western medicine. The two medical systems exhibit distinct focuses and complementary advantages in the interpretation of pathogenesis and the formulation of diagnosis and treatment strategies. This paper systematically reviews the epidemiological characteristics, pathological basis, pathogenesis and current Western medical treatment status of dengue fever, and further elaborates the etiology, pathogenesis, lesion location, syndrome differentiation and treatment system, as well as research progress of traditional Chinese medicine for this disease. It aims to provide references for the optimization of clinical diagnosis and treatment and the expansion of scientific research directions on dengue fever.
【摘要】 目的 系统分析音乐干预对眼科手术患者围手术期焦虑与生理反应的影响,为其临床应用提供参考。方法 系统检索国内外相关文献,从患者焦虑特征、理论基础、实施方法、干预效果及影响因素等方面进行综合分析。结果 眼科手术患者围术期焦虑发生率较高,焦虑可降低术中配合度、增加麻醉用药等风险。音乐干预通过调节边缘系统及自主神经系统发挥作用,术前、术中持续应用可显著降低焦虑评分,稳定心率、降低血压。听觉敏感性、基线焦虑水平、年龄及干预方案特征是影响干预效果的关键因素。结论 音乐干预能有效缓解眼科手术患者围手术期焦虑,具有良好应用潜力。未来需开展大样本随机对照试验,结合人工智能等技术开发个性化方案,并建立标准化实施方法。
【Abstract】Objective To systematically evaluate the effects of music intervention on perioperative anxiety and physiological responses in ophthalmic surgery patients, and to provide evidence for clinical practice. Methods Domestic and international literature on anxiety characteristics, mechanisms, implementation, efficacy, and influencing factors was systematically searched and reviewed. Results Perioperative anxiety is common in ophthalmic surgery patients and may reduce intraoperative cooperation and increase anesthetic consumption. Music intervention acts on the limbic system and the autonomic nervous system, and can effectively reduce anxiety scores, stabilize heart rate, and lower blood pressure when applied preoperatively and intraoperatively. Key influencing factors include auditory sensitivity, baseline anxiety, age, and intervention features. Conclusions Music intervention safely and effectively relieves perioperative anxiety in ophthalmic surgery patients. Further large-sample randomized controlled trials, AI-based personalized programs, and standardized protocols are needed.
脑卒中后认知障碍(PSCI)是脑卒中患者常见的并发症,严重影响患者的生活质量和社会功能。近年来,随着认知储备理论的发展和早期干预理念的普及,PSCI的早期干预模式逐渐成为研究热点。文章综述了PSCI早期干预模式的研究现状与进展,包括干预的理论基础、具体措施及未来发展方向,以期为临床实践和科研提供参考。
Post-stroke cognitive impairment(PSCI)is a common complication among stroke patients.It seriously affects the patients’ quality of life and social functions.In recent years,with the development of the cognitive reserve theory and the popularization of the concept of early intervention,the early intervention model for PSCI has gradually become a research hotspot.This article reviews the current research status and progress of the early intervention model for PSCI,including the theoretical basis of the intervention,specific measures,and future development directions,aiming to provide references for clinical practice and scientific research.
目的 分析广东省卒中中心建设现状及存在的问题,提出切实可行的改善建议。方法 基于广泛的文献调研, 通过问卷对广东省护士协会卒中中心建设与管理分会相关单位开展问卷调查, 统计分析其在医院管理制度、医护人员卒中救治水平及健康宣教等方面的现状与问题。结果 广东省卒中中心建设与管理委员会相关单位在卒中救治中基本实现跨学科合作, 院前评估制度基本满足卒中判断需求, 在提高卒中救治效率方面已基本形成共识, 卒中健康宣教基本满足患者需求, 但方式有待改进, 卒中随访制度和个案管理制度基本符合要求; 存在的问题包括卒中中心一线救治人员外出交流学习机会较少; 院前评估数据采集的便利性有待提高; 卒中康复需求仍难以满足; 健康宣教工作仍需加强。结论 广东省卒中中心建设与管理委员会相关单位在卒中院前评估、院内救治、出院随访和健康宣教方面能够满足患者需求, 但仍存在不足。建议相关单位为一线工作人员提供更多外出交流学习机会, 充分应用互联网和物联网技术提高院前卒中数据采集共享便利性; 加强多种形式的科普宣教, 继续完善拓展卒中康复治疗和护理服务并完善相关制度。
Objective To understand the current situation of construction and existing problems of Stroke Center in Guangdong Province.Put forward feasible suggestions for improvement.Methods Based on extensive literature research, a questionnaire was designed to investigate the relevant organizations of Stroke Center Construction and Management Branch of Guangdong Nurses Association.The status quo and existing problems in hospital management system, stroke treatment level of medical staff, health education and other aspects were statistically analyzed.Results The relevant organizations of the Guangdong Stroke Center Construction and Management Committee could basically achieve interdisciplinary cooperation in stroke treatment, the pre-hospital assessment system basically met the needs of stroke judgment, and a consensus was basically reached on how to improve the efficiency of stroke treatment.Stroke health education basically met the needs of patients but the methods need to be improved.The stroke follow-up system and case management system basically met the requirements,but there were not many opportunities for first-line treatment personnel in stroke centers to exchange and study abroad.The convenience of data collection for pre-hospital assessment needed to be improved.Stroke rehabilitation needs were still difficult to meet.Health education still needs to be strengthened.Conclusions The relevant units of Guangdong Stroke Center Construction and Management Committee can meet the needs of patients in the aspects of pre-hospital assessment, in-hospital treatment,discharge follow-up and health education, but there are still shortcomings.It is suggested that relevant organizations provide more opportunities for front-line staff to exchange and study abroad, make full use of Internet and Internet of Things technology to improve the convenience of pre-hospital stroke data collection and sharing.Strengthen various forms of science popularization and education, and continue to improve and expand stroke rehabilitation treatment and nursing services, improve relevant systems.