目的 对比内镜逆行阑尾炎治疗术(ERAT)与腹腔镜阑尾切除术(LA)治疗急性化脓性阑尾炎(ASA)的效果。方法 按随机数字表法将2022年7月-2025年12月本院收治的106例SAS患者分为对照组(LA治疗)及观察组(ERAT治疗),各53例。比较两组围手术期指标、术后恢复指标、炎症因子水平[C反应蛋白(CRP)、白介素-6(IL-6)、降钙素原(PCT)]、疼痛介质水平[P物质(SP)、前列腺素E2(PGE2)、5-羟色胺(5-HT)]、免疫功能、胃肠激素[胃泌素(GAS)、血管活性肠肽(VIP)、胃动素(MTL)]、并发症、复发率。结果 观察组较对照组术中出血量更少,手术、住院时间与肛门排气、首次下床活动、体温复常及术后进食时间更短,并发症发生率更低;术后48h的CRP、IL-6、PCT、SP、PGE2、5-HT及VIP水平更低,CD3+、CD4+、CD4+/CD8+与GAS、MTL水平更高,有统计学差异(P<0.05);术后3个月内,两组均无1例复发。结论 与LA治疗ASA相比,ERAT具有创伤小、恢复快、炎症反应轻、并发症少等优势,且对免疫功能、胃肠功能影响小等优势,值得临床借鉴。
目的 探究改良宫腹腔镜术治疗输卵管积水性不孕症(HAI)的效果。方法 回顾性分析2023年6月~2025年3月本院收治的80例HAI患者资料,依据手术方法不同分为对照组(40例,传统宫腹腔镜术)、观察组(40例,改良宫腹腔镜术)。两组术后均随访12个月。对比两组自然妊娠率、输卵管通畅率、积水复发率、手术指标及住院时间及术后并发症发生率;对比两组术前、术后1d、术后3d的C反应蛋白(CRP)、降钙素原(PCT)、D-二聚体(D-D)水平。结果 观察组自然妊娠率、输卵管通畅率较对照组高,积水复发率较低(P<0.05)。两组手术时间、术中出血量对比无差异(P>0.05);观察组住院时间较对照组短,并发症较少(P<0.05)。术后1d、术后3d,两组CRP、PCT、D-D均高于术前,术后3d均低于术后1d,观察组均较对照组低(P<0.05)。结论 改良宫腹腔镜术可以提高HAI患者的自然妊娠率、输卵管通畅率,降低积水复发率,且能减轻患者的术后炎症及高凝状态,降低并发症发生率,缩短住院时间。
探讨将 Root Cause Analysis(RCA)质量管理模式与心理资本理论相结合应用于手术核查团队,对改善沟通中断、提升沟通执行质量与团队协作能力的效果。方法 选取 2025年 1 月至 2025 年12 月某三级医院手术室手术团队成员 80 名,按手术间编号分为对照组与实验组,各 40 名。对照组实施常规手术核查流程;实验组在此基础上实施基于 RCA 的流程诊断与基于心理资本理论的综合沟通能力提升干预。干预结束后,比较两组沟通中断发生率、核查流程执行质量、沟通效率,以及心理资本量表(PCQ-24)和团队协作量表(T-TPQ)得分。结果 实验组沟通中断发生率显著低于对照组(P<0.05),核查流程执行质量和沟通效率均显著优于对照组(P<0.001)。实验组 PCQ-24 各维度及总分、T-TPQ 各维度及总分均显著高于对照组(均 P<0.001)。结论 将 RCA 流程分析与心理资本理论干预相结合,可通过流程规范化与心理动力增强双路径同步改善手术团队沟通质量与协作水平,具有良好的临床应用价值与推广潜力。
To evaluate the effectiveness of an intervention combining Root Cause Analysis (RCA)–based quality management and Psychological Capital (PsyCap) theory in reducing communication interruptions and improving communication quality and teamwork in surgical safety check teams. Methods: Eighty surgical team members from a tertiary hospital (January 2025 - December 2025.) were assigned to a control group or an intervention group according to operating room allocation (40 per group). The control group followed routine surgical safety check procedures, whereas the intervention group additionally received an RCA-guided workflow analysis and a PsyCap-based communication enhancement program. Post-intervention outcomes included communication interruption rate, execution quality and efficiency of safety checks, Psychological Capital Questionnaire (PCQ-24) scores, and TeamSTEPPS Teamwork Perceptions Questionnaire (T-TPQ) scores. Results: The intervention group demonstrated a significantly lower communication interruption rate compared with the control group (P<0.05). Execution quality and communication efficiency were significantly improved in the intervention group (P<0.001). PCQ-24 total and subscale scores were significantly higher in the intervention group than in the control group (P<0.001), as were T-TPQ total and subscale scores (P<0.001). Conclusion: Integrating RCA-based workflow optimization with PsyCap-oriented psychological and behavioral training can effectively enhance communication quality, reduce interruptions, and strengthen teamwork in surgical safety check teams. The combined model has strong applicability and potential for wider clinical promotion.
动脉粥样硬化(AS)是心血管疾病的病理基础,口腔与肠道通过菌群移位、代谢互作及免疫联动共同构成口腔-肠道微生物轴,其稳态失衡通过菌群易位、代谢紊乱和屏障损伤等促进AS发生发展。中医药以整体观念与辨证论治为指导,多靶点调控口腔-肠道微生物平衡,抑制血管炎症与脂质沉积,发挥抗AS效应。本文系统阐述口腔-肠道微生物与AS的关联,探讨中医药调控微生态防治该病的研究进展,分析当前研究存在的局限并展望未来方向,为中医药防治AS提供新的思路与理论依据。
Atherosclerosis (AS) is the pathological basis of cardiovascular diseases. The oral cavity and the gut together constitute the oral-gut microbial axis through microbial translocation, metabolic interactions, and immune crosstalk. Dysbiosis of this axis promotes the occurrence and development of AS via bacterial translocation, metabolic disorders, and barrier damage. Guided by the holistic concept and syndrome differentiation-based treatment, traditional Chinese medicine (TCM) exerts anti-AS effects by multi-target regulation of the oral-gut microbial balance, inhibiting vascular inflammation and lipid deposition. This article systematically elaborates the association between the oral-gut microbiota and AS, explores the research progress of TCM in modulating microecology for the prevention and treatment of AS, analyzes the limitations of current studies, and prospects future directions, so as to provide new insights and theoretical basis for TCM in preventing and treating AS.
目的:分析尿毒症维持性血液透析(MHD)患者红细胞相关指标、铁代谢指标水平及其同肾性贫血的关系。方法:选取我院2024年10月-2025年10月期间尿毒症MHD患者70例为研究对象,依照其是否发生肾性贫血分为贫血组(49例)、无贫血组(21例),对比两组患者红细胞相关指标以及等铁代谢指标,同时对比不同贫血严重程度患者各项指标水平差异,并分析尿毒症MHD患者肾性贫血的相关影响因素。结果:贫血组、无贫血组患者红细胞血红蛋白浓度(MCHC)、总铁结合力(TIBC)水平无较大差异(P>0.05),贫血组患者网织红细胞计数(Ret)、血清铁蛋白(SF)、转铁蛋白(TRSF)水平低于无贫血组、平均红细胞体积(MCV)水平高于无贫血组(P<0.05);轻度组、中度组、重度组患者Ret、MCV、SF、TRSF差异显著(P>0.05);不同贫血严重程度患者MCHC、TIBC水平比较,差异无统计学意义(P>0.05);多因素Logistic回归结果显示,Ret(OR=0.2063)、MCV(OR=4.152)、SF(OR=0.341)、TRSF(OR=0.281)是尿毒症MHD患者发生肾性贫血的重要影响因素(P<0.05)。结论:尿毒症MHD患者存在较高的肾性贫血风险,且不同贫血程度患者的Ret、MCV及SF、TRSF等指标水平存在差异性,亦是患者发生肾性贫血的重要影响因素。
Objective: To analyze the levels of red blood cell related indicators, iron metabolism indicators and their relationship with renal anemia in uremic patients with maintenance hemodialysis (MHD). Methods: 70 cases of uremic MHD patients in our hospital from October 2024 to October 2025 were selected as the research object, and were divided into anemia group (49 cases) and non anemia group (21 cases) according to whether renal anemia occurred. The red blood cell related indexes and iron metabolism indexes of the two groups were compared, and the differences of various indexes in patients with different anemia severity were compared, and the related influencing factors of renal anemia in uremic MHD patients were analyzed. Results: there was no significant difference in the levels of erythrocyte hemoglobin concentration (MCHC) and total iron binding capacity (TIBC) between anemia group and non anemia group (P>0.05). The levels of reticulocyte count (RET), serum ferritin (SF), transferrin (trsf) in anemia group we
目的 比较锝[???Tc]甲氧基异丁基异腈单光子发射计算机断层扫描/计算机断层扫描(???Tc-MIBI SPECT/CT)双时相显像与颈部超声在继发性甲状旁腺功能亢进症(SHPT)患者术前定位中的诊断价值。方法 回顾性纳入2025年5月至2026年4月于黔东南苗族侗族自治州人民医院行两种影像学检查的疑似SHPT患者54例。以手术病理结果为金标准,计算超声与SPECT/CT在区域层面(共216个区域)的敏感性、特异性、准确性,并比较不同解剖区域的病灶检出率。结果 54例中确诊SHPT 45例(83.33%)。超声诊断敏感性、特异性、准确性分别为70.89%(112/158)、86.21%(50/58)、75.00%(162/216);SPECT/CT分别为92.41%(146/158)、94.83%(55/58)、93.06%(201/216)。SPECT/CT的敏感性和准确性均高于超声(P均<0.001)。SPECT/CT在左上、左下、右上三个区域的检出率均高于超声(P<0.05)。结论 99mTc-MIBI SPECT/CT双时相显像在SHPT术前定位中的敏感性和准确性优于颈部超声,尤其对左上、左下、右上区域病灶检出优势明显,可作为SHPT患者术前定位的重要补充或首选影像学方法。
Objective?To compare the diagnostic value of technetium-99m methoxyisobutylisonitrile single-photon emission computed tomography/computed tomography (99mTc-MIBI SPECT/CT) dual-phase imaging and cervical ultrasound in preoperative localization of secondary hyperparathyroidism (SHPT).?Methods?A total of 54 patients with suspected SHPT who underwent both imaging examinations at Qiandongnan Miao and Dong Autonomous Prefecture People's Hospital from May 2025 to April 2026 were retrospectively enrolled. Using surgical pathology as the gold standard, the sensitivity, specificity, and accuracy of ultrasound and SPECT/CT were calculated at the regional level (216 regions in total), and the detection rates in different anatomical regions were compared.?Results?Among the 54 patients, 45 (83.33%) were confirmed with SHPT. The sensitivity, specificity, and accuracy of ultrasound were 70.89% (112/158), 86.21% (50/58), and 75.00% (162/216), respectively; while those of SPECT/CT were 92.41% (146/158), 94.83% (55/58), and 93.06% (201/216), respectively. The sensitivity and accuracy of SPECT/CT were significantly higher than those of ultrasound (both?P<0.001). The detection rates of SPECT/CT in the upper-left, lower-left, and upper-right regions were significantly higher than those of ultrasound (P<0.05).?Conclusion?99mTc-MIBI SPECT/CT dual-phase imaging demonstrates superior sensitivity and accuracy compared with cervical ultrasound in preoperative localization of SHPT, especially showing significant advantages in detecting lesions in the upper-left, lower-left, and upper-right regions. It can serve as an important supplement or the first-choice imaging modality for preoperative localization in SHPT patients.
目的 探讨将 Root Cause Analysis(RCA)质量管理模式与心理资本理论相结合应用于手术核查团队,对改善沟通中断、提升沟通执行质量与团队协作能力的效果。方法 选取 2025年 1 月至 2025 年12 月某三级医院手术室手术团队成员 80 名,按手术间编号分为对照组与实验组,各 40 名。对照组实施常规手术核查流程;实验组在此基础上实施基于 RCA 的流程诊断与基于心理资本理论的综合沟通能力提升干预。干预结束后,比较两组沟通中断发生率、核查流程执行质量、沟通效率,以及心理资本量表(PCQ-24)和团队协作量表(T-TPQ)得分。结果 实验组沟通中断发生率显著低于对照组(P<0.05),核查流程执行质量和沟通效率均显著优于对照组(P<0.001)。实验组 PCQ-24 各维度及总分、T-TPQ 各维度及总分均显著高于对照组(均 P<0.001)。结论 将 RCA 流程分析与心理资本理论干预相结合,可通过流程规范化与心理动力增强双路径同步改善手术团队沟通质量与协作水平,具有良好的临床应用价值与推广潜力。
To evaluate the effectiveness of an intervention combining Root Cause Analysis (RCA)–based quality management and Psychological Capital (PsyCap) theory in reducing communication interruptions and improving communication quality and teamwork in surgical safety check teams. Methods: Eighty surgical team members from a tertiary hospital (January 2025 - December 2025.) were assigned to a control group or an intervention group according to operating room allocation (40 per group). The control group followed routine surgical safety check procedures, whereas the intervention group additionally received an RCA-guided workflow analysis and a PsyCap-based communication enhancement program. Post-intervention outcomes included communication interruption rate, execution quality and efficiency of safety checks, Psychological Capital Questionnaire (PCQ-24) scores, and TeamSTEPPS Teamwork Perceptions Questionnaire (T-TPQ) scores. Results: The intervention group demonstrated a significantly lower communication interruption rate compared with the control group (P<0.05). Execution quality and communication efficiency were significantly improved in the intervention group (P<0.001). PCQ-24 total and subscale scores were significantly higher in the intervention group than in the control group (P<0.001), as were T-TPQ total and subscale scores (P<0.001). Conclusion: Integrating RCA-based workflow optimization with PsyCap-oriented psychological and behavioral training can effectively enhance communication quality, reduce interruptions, and strengthen teamwork in surgical safety check teams. The combined model has strong applicability and potential for wider clinical promotion.
心房分离(atrial dissociation)有阻滞性心房分离和干扰性心房分离之分。其中阻滞性心房分离又称为局限性完全性心房内传导阻滞或心房脱节,系指心房肌的某一部分与心房肌的其余部分,分别由两个独立的、互不干扰的起搏点所激动。通常前者由心房内异位起搏点控制,且绝不下传心室;后者多由窦性节律控制,且下传心室产生QRS波群