论著

肝癌根治术后恶心呕吐现状及影响因素分析

Analysis of the status and influencing factors of nausea and vomiting after radical resection of liver cancer

:1245-1250
 
目的 探讨肝癌根治术后恶心呕吐现状及影响因素。方法 选取2022年5月—2024年5月天津市第二人民医院收治的70例肝癌患者进行回顾性分析,所有患者均行肝癌根治术,分析其术后恶心呕吐情况。并依照恶心呕吐发生情况进行分组,将30例术后发生恶心呕吐的患者分为观察组,其余40例患者为对照组。对比两组患者临床病理特征及围术期指标。并建立Logistic回归模型以术后恶心呕吐为因变量分析肝癌患者手术切除术后恶心呕吐的影响因素。结果 肝癌患者手术切除术后恶心呕吐发生率为42.86%(30/70),其中Ⅰ度14例(20.00%)、Ⅱ度10例(14.29%)、Ⅲ度4例(5.71%)、Ⅳ度2例(2.86%);观察组与对照组性别、体质量指数(BMI)、病理类型、临床分期、术前禁食时间对比差异无统计学意义(P>0.05),观察组与对照组年龄及是否化疗情况对比差异有统计学意义(P<0.05);观察组与对照组手术时间、术后VAS评分、麻醉方式、术后合并其他并发症情况对比差异无统计学意义(P>0.05),观察组与对照组肝门阻断时间、术中失血量及术后腹胀情况对比差异有统计学意义(P<0.05);年龄、是否化学治疗、术中失血量、术后腹胀情况为肝癌患者手术切除术后恶心呕吐的影响因素(P<0.05)。结论 肝癌患者手术切除术后恶心呕吐发生率较高,且年龄、是否化疗、术中失血量及术后腹胀情况可能为恶心呕吐发生的影响因素,针对此类患者高风险患者需及时采取相关措施进行干预,预防患者术后恶心呕吐情况及减轻严重程度。
Objective To explore the status and influencing factors of nausea and vomiting after radical resection of liver cancer. Methods A retrospective analysis was conducted on 70 liver cancer patients admitted to the Second People’s Hospital of Tianjin from May 2022 to May 2024. All patients underwent radical surgery for liver cancer,and their postoperative nausea and vomiting conditions were analyzed. According to the occurrence of nausea and vomiting, 30 patients who experienced nausea and vomiting after surgery were divided into an observation group, and the remaining 40 patients were divided into a control group. The clinical and pathological characteristics as well as perioperative indicators between two groups of patients were compared. A logistic regression model was established to analyze the influencing factors of postoperative nausea and vomiting in liver cancer patients after surgical resection,with postoperative nausea and vomiting as the dependent variable. Results The incidence of postoperative nausea and vomiting in liver cancer patients was 42. 86%(30/70), including 14 cases of grade I, accounting for 20. 00%, 10 cases of grade II, accounting for 14. 29%, four cases of grade III,accounting for 5. 71%, and two cases of grade IV,accounting for 2. 86%. There were no significant differences in gender,body mass index(BMI), pathological type,clinical stage,and preoperative fasting time between the observation group and the control group(P>0. 05). However, there were significant differences in age and chemotherapy status between the observation group and the control group(P<0. 05). There were no significant differences in the operation time,postoperative VAS score,anesthesia method and postoperative complications between the observation group and the control group(P>0. 05), but with differences in the portal block time,intraoperative blood loss and postoperative abdominal distension between the observation group and the control group(P<0. 05). Age, chemotherapy, intraoperative blood loss, and postoperative abdominal distension were independent influencing factors for postoperative nausea and vomiting in liver cancer patients undergoing surgical resection(P<0. 05). Conclusions The incidence of nausea and vomiting after surgical resection in liver cancer patients is relatively high, with age, chemotherapy, intraoperative blood loss, and postoperative abdominal distension may be influencing factors for nausea and vomiting. Therefore, relevant measures should be taken in a timely manner to intervene in high-risk patients to prevent postoperative nausea and vomiting and reduce its severity.
论著

肾移植术后患者膀胱痉挛发生现状及影响因素

The current situation and influencing factors of bladder spasms in patients after kidney transplantation

:1225-1231
 
目的 探讨肾移植术后患者膀胱痉挛发生现状及影响因素。方法 选取广州医科大学附属第一医院2022年12月—2024年4月收治的80例肾移植患者为研究对象,记录术后膀胱痉挛发生情况,将15例术后发生膀胱痉挛的患者纳入膀胱痉挛组,其余65例患者纳入非膀胱痉挛组。对比两组一般人口学资料,术前临床资料、术中及术后情况。以合并膀胱痉挛作为因变量纳入Logistics回归模型分析肾移植术后膀胱痉挛发生的影响因素。结果 80例肾移植患者在术后共有15例患者发生膀胱痉挛,占比为18.76%。膀胱痉挛组与非膀胱痉挛组的性别、年龄、体质指数、文化程度、付费方式、家庭收入比较差异无统计学意义(P>0.05);两组原发疾病、合并基础疾病、透析方式比较差异无统计学意义(P>0.05),两组患者术前透析时间及术前贫血情况比较差异有统计学意义(P<0.05);两组手术时间、术中出血量、术后尿管留置时间、术后尿潴留、术后视觉模拟量表评分、C反应蛋白、肿瘤坏死因子-α、白细胞介素-6、碱性磷酸酶、谷草转氨酶、肌酐、尿素氮、胱抑素C比较差异无统计学意义(P>0.05),两组使用尿管材质、术后7 d平均尿量比较差异有统计学意义(P<0.05);根据Logistics回归分析结果显示,术前透析时间(95%CI:1.327~9.846,OR:3.614,P=0.012)、术前贫血(95%CI:0.995~1.000,OR:0.997,P=0.045)、尿管材质(95%CI:1.498~3 199.687,OR:69.239,P=0.030)及术后7 d平均尿量(95%CI:1.058~334.543,OR:18.813,P=0.046)为肾移植术后膀胱痉挛发生的独立影响因素(P<0.05)。结论 肾移植患者术前透析时间较长、术前贫血、应用尿管材质较硬、术后尿量少均可增加术后膀胱痉挛发生风险,因此需针对膀胱痉挛高风险患者增加护理评估,监测患者术后尿量,尽量选择软质尿管,预防肾移植术后膀胱痉挛的发生。
Objective To explore the current situation and influencing factors of bladder spasms in patients after kidney transplantation. Methods Selecting 80 kidney transplant patients admitted to the First Affiliated Hospital of Guangzhou Medical University from December 2022 to April 2024 as the research subjects, the occurrence of postoperative bladder spasm was recorded. Fifteen patients who experienced bladder spasm after surgery were included in the bladder spasm group, and the remaining 65 patients were included in the non bladder spasm group. The general demographic data,preoperative clinical data, intraoperative and postoperative conditions between two groups were compared. Incorporating bladder spasm as the dependent variable into the Logistics regression model to analyze the influencing factors of bladder spasm after kidney transplantation. Results A total of 15 out of 80 kidney transplant patients experienced bladder spasms after surgery, accounting for 18. 76%. By comparing general demographic data between the bladder spasm group and the non bladder spasm group, it was found that there were no significant differences in gender, age, Body Mass Index, education level, payment methods, and household income(P>0. 05). There was no significant differences in primary disease, combined basic disease, and dialysis method between the two groups(P>0. 05),while there were significant differences in preoperative dialysis time and preoperative anemia between the two groups(P<0. 05). Surgical time, intraoperative blood loss,postoperative urinary retention, postoperative visual analog scale score, C reactive protein, tumor necrosis factor-α, interleukin-6, alkaline phosphatase, transaminase, creatinine, urea nitrogen, cystatin C were not different between the two groups(P>0. 05). The difference in the mean urine volume after seven days and urinary catheter material were significant(P<0. 05). According to the results of the Logistic regression analysis,preoperative dialysis duration(95%CI:1. 327-9. 846,OR:3. 614, P=0. 012), preoperative anemia(95%CI:0. 995-1. 000,OR:0. 997, P=0. 045), catheter material(95%CI:1. 498-3 199. 687,OR:69. 239, P=0. 030), and mean urine output at seven days postoperatively(95%CI:1. 058-334. 543,OR:18. 813, P=0. 046)were identified as independent influencing factors for the occurrence of bladder spasms after kidney transplantation(P<0. 05). Conclusions Renal transplant patients have a longer preoperative dialysis time, and the use of harder urinary catheter materials and lower postoperative urine output can increase the risk of postoperative bladder spasms. Therefore, it is necessary to increase nursing evaluation for high-risk patients with bladder spasms mentioned above, monitor postoperative urine output, and choose soft urinary catheters as much as possible to prevent the occurrence of bladder spasms after kidney transplantation.
专家述评

股骨转子间骨折内固定术后头颈钉位置评估的研究进展

Advances in evaluation methods for cephalic fixator position in femoral intertrochanteric fractures after internal fixation

:1158-1164
 
股骨转子间骨折是最常见的髋部骨折,内固定手术为其目前治疗的首选方式。头颈钉位置是评估手术效果和判断治疗预后的重要因素,合适的置钉位置有利于稳定骨折、加速康复以及改善预后。目前头颈钉位置最经典的评估方式为尖顶距(TAD),但TAD至今仍存在较多争议。近年来提出的轴刀角、尖颈距离比、偏心距(ED)以及标准化TAD(STAD)为临床实践拓展了新视野。文章通过对上述头颈钉位置的评估方法及局限性进行文献综述,旨在为临床手术置钉时提供相应的参考。ED和STAD的提出,为未来人工智能评估头颈钉位置提供了可能。
Femoral intertrochanteric fracture is one of the most common hip fractures, and the internal fixation is the preferred treatment. The position of cephalic fixator is an important factor to evaluate the effect of operation and the prognosis of treatment. Tip-apex-distance(TAD)is the most classical method to evaluate the position of cephalic fixator, but it is still controversial. In recent years, the axis-blade angle,tip-neck distance ratio, eccentric distance(ED)and standardized TAD(STAD)have been proposed,though with limitations, they also provide a new perspective for clinical practice. In this study, we reviewed the literature on the evaluation of the position of cephalic fixator in order to provide the corresponding references and guidance for the clinical operation of internal fixation. Both STAD and ED may be the theoretical possibility of artificial intelligence evaluation of the position of cephalic fixator in the future.
论著

高原地区儿童阑尾炎术后早期炎性肠梗阻治疗分析

Treatment analysis of appendicitis early postoperative inflammatory small bowel obstruction in plateau area children

:893-897
 
      目的   回顾分析高原地区儿童阑尾炎术后早期炎性肠梗阻的临床特征,总结治疗经验。方法   回顾分析青海省妇女儿童医院2019—2023年收治的49例儿童阑尾炎术后早期炎性肠梗阻病例资料。结果   纳入研究的49例患儿,阑尾炎发病时间3~8 d,平均(5.38±1.25)d,术后出现肠梗阻时间3~11 d,平均时间(4.81±1.70)d,其中48例经过保守治疗后梗阻解除,恢复排气、排便,肠功能恢复时间4~13 d,平均(5.93±2.49)d,1例经积极保守治疗后病情进展,最终经手术治愈。49例患儿均顺利治愈出院,住院时间10~26 d,平均(15.69±3.79)d。术后随访1~2年,患儿饮食、排便均无异常。结论   高原地区儿童阑尾炎术后早期粘连性肠梗阻预防是关键,采取保守治疗同样可获得较高的治愈率,若保守治疗无效或病情进展应及时积极采取手术治疗。
       Objective  To review the clinical characteristics of early postoperative inflammatory small bowel obstruction(EPISBO) in children with appendicitis in plateau area and summarize the treatment experience.Methods  The data of 49 cases of appendicitis EPISBO in children admitted to Qinghai Women and Children’s Hospital from 2019 to 2023 were  retrospectively analyzed.Results  The onset time of appendicitis was 3-8 days,with an average of(5.38±1.25)days,and the time of intestinal obstruction was 3-11 days after surgery,with an average of(4.81±1.70)days.After conservative treatment,48 cases were relieved of obstruction,resumed exhaust and defecation,and intestinal function recovered in 4-13 day,average(5.93±2.49)d,1 case had progression after conservative treatment,and was cured by surgery.All the 49 children were successfully cured and discharged.The length of hospital stay was 10-26 days,with an average of(15.69±3.79)days.Postoperative follow-up of 1 to 2 years showed normal eating and bowel movements.Conclusions  The prevention of EPISBO in children with appendicitis in plateau area is the key.Conservative treatment can also achieve a higher cure rate.If conservative treatment is ineffective or the disease progresses,timely surgical treatment should be provided.

论著

钝性分离扩皮法与常规扩皮法在乳腺癌术后患者 PICC 置管中的应用效果

Application effect of blunt separating skin expansion and conventional skin expansion in PICC catheterization for patients with breast cancer after operation

:798-803
 
       目的  对比分析钝性分离扩皮法与常规扩皮法对乳腺癌术后患者经外周静脉置入中心静脉导管(PICC)置管应用效果。方法  选取2022年4月—2024年4月在天津肿瘤医院空港医院接受治疗的120例乳腺癌术后PICC置管患者,依据随机数字表法进行分组处理。对照组60例给予常规扩皮法,观察组60例给予钝性分离扩皮法,对比两组患者扩皮结果。结果  观察组患者满意度为96.67%,对照组患者满意度为86.67%(χ 2 =3.927,P=0.048);观察组患者的穿刺点血液浸湿面积分别为穿刺后即刻(0.87±0.14)cm2 、1 d后(4.89±0.94)cm2 以及3 d后(0.21±0.05)cm2 ,均低于对照组的(2.74±0.63)(9.89±2.04)(0.44±0.12)cm2 ,对比差异有统计学意义(t=22.444、17.243、13.704,P<0.05);观察组患者一次性送鞘成功率为98.33%,对照组患者一次性送鞘成功率为88.33%,观察组高于对照组(χ 2 =4.821,P=0.028);扩皮前两组患者的VAS评分无差异(P>0.05),扩皮后两组患者的VAS评分均降低,且观察组(1.75±0.54)分低于对照组(3.89±1.22)分,对比差异有统计学意义(t=12.425,P<0.001);观察组患者不良事件发生率为5.00%,对照组患者不良事件发生率为16.67%,观察组患者不良事件发生率低于对照组(χ 2 =4.227,P<0.05)。结论  钝性分离扩皮法能够降低穿刺点血液浸湿面积及不良事件发生率,提高一次性送鞘成功率,减轻患者疼痛感,提高患者满意度。
       Objective  To analyze the effect of blunt separating skin expansion and conventional skin expansion in PICC catheterization of patients after breast cancer surgery.Methods  From April 2022 to April 2024,120 patients with postoperative PICC catheterization for breast cancer were selected and grouped according to the random number table method.Sixty patients in the control group received conventional skin expansion,and 60 patients in the observation group  received blunt separation skin expansion,which the results of the two groups were compared.Results  The patient satisfaction was 96.67% in the observation group,86.67% in the control group(χ 2 =3.927,P=0.048,P<0.05).In the observation group,the blood immersion area after catheterization,after 1 d and 3 d were(0.87±0.14),(4.89±0.94),(0.21±0.05)cm2 ,lower than those of the control group [(2.74±0.63)(9.89±2.04)(0.44±0.12)cm2 ],the comparative difference was statistically significant(t=22.444,17.243,13.704,P<0.05).The success rate of disposable sheath delivery in the observation group was 98.33%,which was higher than 88.33% in the control group(χ 2 =4.821,P=0.028<0.05).There was no difference in VAS scores between the two groups before the intervention(P>0.05),VAS scores decreased in both groups after the intervention,the score of the observation group(1.75±0.54)was lower than that of the control group(3.89±1.22),the difference was statistically significant(t=12.425,P<0.001).The incidence of adverse events in the observation group was 5.00%,and in the control group was 16.67%,which difference was significant(χ 2 =4.227,P<0.05).Conclusions  Blunt separating skin expansion can  reduce the area of blood immersion and the incidence of adverse events,improve the success rate of disposable sheath delivery,reduce patient pain,improve patient satisfaction,and have significant clinical application value.
论著

心脏瓣膜置换术后患者异常出血的判断与处理

Diagnosis and management of abnormal bleeding in patients after heart valve replacement surgery

:754-759
 
      目的  探讨心脏瓣膜置换术后患者异常出血的判断与处理。方法  选取2020年1月—2024年5月广州医科大学附属第一医院收治的30例心脏瓣膜置换术后异常出血的患者,将其纳入观察组,另选取同期收治的200例心脏瓣膜置换术后未出现异常出血的患者为对照组。对比两组患者预后情况和两组患者舒张压、收缩压、心率、术后3 h内引流量相关异常出血判断相关指标情况。采用Logistics回归模型分析心脏瓣膜置换术后患者异常出血的影响因素。结果   观察组住院时间、左心室射血分数(LVEF)水平高于对照组,左室舒张末期内径低于对照组,且观察组术后感染、心律失常、低心排综合征发生率高于对照组(P<0.05);观察组术后舒张压、收缩压、心率及术后3 h内引流量高于对照组(P<0.05);观察组与对照组患者吸烟史、合并糖尿病、抗凝依从性比较差异有统计学意义(P<0.05);吸烟史、抗凝依从性为心脏瓣膜置换术后患者异常出血的影响因素(P<0.05)。结论  心脏瓣膜置换术后患者异常出血的发生可严重影响患者预后水平,增加患者并发症发生率,影响心功能恢复,通过舒张压、收缩压、心率及术后3 h内引流量可为异常出血的判断提供参考意见。另外,吸烟史、抗凝依从性为心脏瓣膜置换术后患者异常出血的独立影响因素,因此对异常出血患者进行常规治疗的同时要密切监测患者危险因素,实施科学的护理干预,改善患者抗凝依从性,降低异常出血发生率。
       Objective  To explore the  diagnosis and management of abnormal  bleeding in  patients after  heart valve replacement surgery.Methods  Thirty patients with abnormal bleeding after heart valve  replacement surgery admitted to the First Affiliated Hospital of Guangzhou Medical University from January 2020 to May 2024 were  retrospectively analyzed and divided into an observation group.In addition,200 patients who did not experience abnormal bleeding after heart valve  replacement surgery admitted during the same period were selected as the control group.Prognosis of two groups of patients were compared,and the related indicators of diastolic blood pressure,systolic blood pressure,heart rate,and abnormal bleeding  related to drainage flow within 3 hours after surgery were evaluated.Finally,the logistic  regression model was used to analyze the influencing factors of abnormal bleeding in patients after heart valve replacement.Results  The length of hospital stay and left ventricular ejection fractionin the observation group were higher than those in the control group,and the left ventricular end diastolic diameter was lower in the observation group than in the control group,and the incidence of postoperative infection,arrhythmia,and low cardiac output syndrome was significantly higher in the observation group than in the control group(P<0.05).The postoperative diastolic blood pressure,systolic blood pressure,heart rate,and drainage volume within 3 hours in the observation group were significantly higher than those in the control group(P<0.05).The smoking history,diabetes,and anticoagulation compliance were different between the observation and control groups(P<0.05).A history of smoking and adherence to anticoagulation were independent influencing factors for abnormal bleeding in patients after heart valve replacement(P<0.05).Conclusions  The occurrence of abnormal bleeding in patients after heart valve replacement can greartly affect the patient’s prognosis,increase the incidence of complications,and affect cardiac function recovery.Reference opinions can be provided for the diagnosis of abnormal bleeding based on diastolic blood pressure,systolic blood pressure,heart rate,and postoperative drainage volume within three hours.In addition,a history of smoking and adherence to anticoagulation are independent influencing factors for abnormal bleeding in patients after heart valve replacement.Therefore,while routine treatment is performed on patients with abnormal bleeding,close monitoring of patient  risk factors is necessary,scientific nursing interventions should be implemented to improve patient adherence to anticoagulation and reduce the incidence of abnormal bleeding.
论著

实时图像引导系统对乳腺癌保乳术后放疗摆位误差的影响

Effects of image-guided radiation therapy on radiotherapy positioning error after breast conserving surgery for breast cancer

:656-661
 
       目的   探讨与分析实时图像引导系统对乳腺癌保乳术后放射治疗(放疗)摆位误差的影响。方法   选取安阳市肿瘤医院2021年9月—2023年12月收治的乳腺癌保乳术后108例患者为研究对象,按照随机信封抽签法把108例患者分为实时组54例与对照组54例。两组的放疗观察时间均为3个月,对照组给予热塑体模定位,实时组给予实时图像引导系统定位,记录两组的摆位误差与放疗不良反应发生情况。结果   实时组X轴、Y轴、Z轴方向的配准结果误差发生率分别为1.85%、7.41%、1.85%,均低于对照组的14.81%、22.22%、16.67%(χ 2 =5.939,P=0.015;χ 2 =4.696,P=0.030;χ 2 =7.053,P=0.008)。实时组摆位纠正前X轴、Y轴、Z轴误差大于对照组(t分别为38.888、28.106、50.102,P<0.05),摆位纠正后两组摆位误差对比差异无统计学意义(P>0.05)。实时组放疗3个月期间的心脏平均受量、肺脏平均受量均少于对照组(t分别为49.942、13.996,P<0.001)。实时组放疗3个月期间的急性放射性皮肤反应发生率为3.70%,对照组为16.67%,实时组低于对照组(χ 2 =4.960,P<0.05)。结论   实时图像引导系统在乳腺癌保乳术后放疗的应用可减少摆位误差,也能减少患者的心脏平均受量、肺脏平均受量,降低急性放射性皮肤反应发生率。
       Objective  To investigate and analysis the effects of image-guided radiation therapy on the positioning error of radiotherapy after breast conserving surgery for breast cancer.Methods  from September 2021 to December 2023,108 patients with breast cancer after breast conserving surgery in Anyang Cancer Hospital were selected as the study subjects.According to the principle of random envelope drawing,108 patients were divided into the real-time group of 54 patients and the control group of 54 patients.The observation time for radiotherapy in both groups was 3 months.The control group was given thermoplastic phantom positioning,while the real-time group was given image-guided radiation therapy positioning.The positioning errors and incidence of radiotherapy adverse reactions were recorded in both groups.Results  The error rates of registration results in the X-axis,Y-axis,and Z-axis directions of the real-time group were 1.85%,7.41% and 1.85%,respectively,which were significantly lower than the control group(14.81%,22.22% and 16.67%;χ 2 =5.939,P=0.015;χ 2 =4.696,P=0.030;χ 2 =7.053,P=0.008).The errors in the X-axis,Y-axis and Z-axis before the pendulum correction were greater than that in the control group(t=38.888,28.106,50.102,P<0.05),and there were no statistically significant difference in positioning errors compared between the two groups after positioning correction(P>0.05).The average cardiac and lung uptake during the 3-month period of real-time radiotherapy in the group were significantly lower than those in the control group(t=49.942,13.996,P<0.001).The incidence of acute radiation-induced skin reactions during the 3-month period of real-time group radiotherapy was 3.70%,compared to 16.67% in the control group,the real-time group showed a significant decrease(χ 2 =4.960,P=0.026<0.05).Conclusions  The application of image-guided  radiation therapy in radiotherapy after breast conserving surgery for breast cancer can reduce the positioning error,the average cardiac and pulmonary dose,and the incidence of acute radiation skin reaction.
论著

预防性风险管理对肌层浸润性膀胱癌根治术后的应用效果及术后生活质量影响

Effect of preventive risk management after surgery and quality of life of myometrial invasive bladder cancer patients

:494-499
 
       目的   探讨预防性风险管理在肌层浸润性膀胱癌根治术后的应用效果及对术后生活质量影响。方法   选取2020年6月—2023年10月安阳市肿瘤医院收治的66例肌层浸润性膀胱癌患者,应用抽签法分为观察组(n=33)与对照组n=33)。所有患者均采取根治性全膀胱切除术与淋巴清扫术治疗,对照组患者术后实施常规护理,观察组在对照组基础上增加预防性风险管理。对比两组术后尿量、胃肠功能恢复时间、术后住院时间,干预前后病耻感及负面情绪、术后并发症发生率,最后对比两组干预前后生活质量变化。结果   两组患者术后尿量对比差异无统计学意义(P>0.05),观察组术后胃肠功能恢复时间为(5.27±0.82)d,术后住院时间为(18.31±3.27)d,短于对照组的(7.25±1.12)(23.27±4.18)d,对比差异有统计学意义(t分别为8.194、5.369,P<0.05);干预后两组患者病耻感量表(SSCI)、抑郁自评量表(SDS)和焦虑自评量表(SAS)评分均降低,观察组分别为(35.67±7.45)(40.02±2.43)(45.36±4.17)分,低于对照组的(48.27±10.69)(54.54±3.54)(51.37±4.38)分,对比差异有统计学意义(t分别为5.555、19.426、5.709,P<0.05);观察组术后并发症发生率为9.09%,低于对照组的30.30%(χ 2 =4.690,P=0.030);干预后两组膀胱癌特异性模块、功能状况、精神状况、家庭/社会状况及躯体状况相关维度膀胱癌患者生活质量量表(FACT-BL)评分均升高,观察组分别为(34.27±3.26)(25.11±4.23)(21.51±4.23)(25.02±4.43)(20.56±3.11)分,高于对照组的(27.00±4.34)(21.11±3.24)(16.12±2.12)(21.54±5.54)(15.87±4.13)分,对比差异有统计学意义(t分别为7.694、4.313、6.544、2.818、5.211,P<0.05)。结论   预防性风险管理在肌层浸润性膀胱癌根治术后的应用效果显著,可缩短患者术后胃肠功能恢复时间及住院时间,改善患者负面情绪,有助减少术后并发症,提升患者生活质量。
       Objective  To explore the effect of preventive risk management on postoperative application and quality of life of myometrial invasive bladder cancer patients after radical surgery.Methods  A total of 66 patients with myometrial invasive bladder cancer admitted to Anyang Cancer Hospital from June 2020 to October 2023 were selected as research objects,and were divided into observation group(n=33)and control group(n=33)by lot drawing.All patients were treated with  radical total cystectomy and lymph node dissection.The control group received routine nursing care after surgery,while the observation group received preventive risk management in addition to the control group.The postoperative urine output,recovery time of gastrointestinal function,and hospitalization time between two groups were compared,as well as the shame and negative emotions before and after intervention,the incidence of postoperative complications,and the changes in quality of life between the two groups before and after intervention.Results  There was no significant difference in postoperative urine volume between the two groups of patients(P>0.05),and the postoperative gastrointestinal function recovery time(5.27±0.82)d,postoperative hospitalization time(18.31±3.27)d were shorter than the control group[(7.25±1.12)d,(23.27±4.18)d],with statistical significantce(t=8.194,5.369,P<0.05).After intervention,the Stigma Scale of Chronic Illness(SSCI),Self Rating Depression Scale(SDS),and Self-Rating Anxiety Scale(SAS)in both groups of patients decreased,and the observation group[(35.67±7.45),(40.02±2.43),(45.36±4.17)]scored lower than the control group[(48.27±10.69),(54.54±3.54),(51.37±4.38)],statistically significantt=5.555,19.426,5.709,P<0.05).The incidence of postoperative complications in the observation group was significantly lower at 9.09% compared to the control group at 30.30%(χ 2 =4.690,P=0.030,P<0.05).After intervention,the scores of bladder cancer specific module,functional status,mental status,family/social status and physical status  related dimensions of bladder cancer patients’ quality of life scale for bladder cancer patients(FACT-BL)in both groups increased,and the observation group[(34.27±3.26),(25.11±4.23),(21.51±4.23),(25.02±4.43),(20.56±3.11)] scored higher than the control group[(27.00±4.34),(21.11±3.24),(16.12±2.12),(21.54±5.54),(15.87±4.13)],the comparison was statistically significant(t=7.694,4.313,6.544,2.818,5.211,P<0.05).Conclusions  Preventive  risk management has a significant effect on the application of myometrial invasive bladder cancer after radical surgery,which can shorten the recovery time of gastrointestinal function and hospital stay,improve patients’ negative emotions,assist in preventing postoperative complications,and improve patients’ quality of life.
论著

非肌层浸润性膀胱癌行初次经尿道膀胱肿瘤电切术的术后复发危险因素分析

Risk factors for relapse after primary transurethral resection on non-muscular invasive bladder cancer

:393-397
 
       目的   探讨非肌层浸润性膀胱癌患者初次经尿道膀胱肿瘤电切术的复发情况及危险因素。方法   以93例非肌层浸润性膀胱癌患者进行研究,2018年1月至2022年1月西藏自治区人民政府驻成都办事处医院泌尿外科医院收治采取经尿道膀胱肿瘤电切术,术后随访24个月,复发22例,未复发71例,比较复发与未复发基础情况、不同肿瘤直径、不同肿瘤分期、分级、数量、是否带蒂、灌注化疗方式等特征患者的复发情况,对具有统计学意义的因素,采取非条件Logistic多因素回归分析,明确术后复发的危险因素。结果   肿瘤分期T1期者的复发率为32.08%,高于Ta期者15.50%,肿瘤分级为高级别者的复发率为53.33%,高于低级别者17.95%,肿瘤多发者的复发率为35.71%,高于单发者的13.73%,肿瘤不带蒂者的复发率为38.71%,高于肿瘤带蒂者的16.13%,常规灌注化疗患者的复发率为29.85%,高于术后即刻+灌注化疗患者的7.69%,比较差异均有统计学意义(χ 2 分别为6.648、4.836、6.872、6.166、5.834、5.902,P分别为0.010、0.027、0.008、0.013、0.015、0.024)。肿瘤分期T1期、肿瘤分级为高级别、肿瘤多发、常规灌注化疗为非肌层浸润性膀胱癌行初次经尿道膀胱肿瘤电切术的术后复发的危险因素(P<0.05)。结论   非肌层浸润性膀胱癌患者初次采取经尿道膀胱肿瘤电切术容易因为临床分期为T1期、肿瘤分级为高级别、肿瘤多发及常规灌注等出现复发,应采取针对性干预措施,改进灌注化疗方式,降低复发率。
       Objective  To investigate the  relapse and  risk factors of non-muscular invasive bladder cancer after primary transurethral resection.Methods  A total of 93 patients with non-muscular invasive bladder cancer were selected for study.They were received by the hospital from January 2018 to January 2022 and underwent transurethral resection.After 24 months of follow-up,22 patients recurred,and 71 patients did not recur.The recurrence of patients with different tumor diameter,tumor stage,grade,numbers,pedicel or not,and infusion chemotherapy methods were compared.For the statistically significant factors,unconditional logistic regression analysis was used to determine the independent risk factors for recurrence.Results  The recurrence rate in T1 stage of tumor was 32.08% higher than that in Ta stage,which was 15.50%.The recurrence rate in high stage was 53.33% higher than that in low stage,which was 17.95%.The recurrence rate in multiple tumor patients was 35.71% higher than that in single tumor patients,which was 13.73%.The no-pedicle tumor recurrence rate was 38.71% higher than that with pedicle,which was 16.13%.The recurrence rate in patients receiving conventional infusion chemotherapy was 29.85% higher than that in patients receiving immediate postoperative infusion chemotherapy,which was 7.69%.The differences were statistically significantχ 2 =6.648、4.836、6.872、6.166、5.834、5.902,P=0.010、0.027、0.008、0.013、0.015、0.024).The independent  risk factors of recurrence after primary transurethral resection were tumor stage T1,high grade tumors,multiple tumors,routine perfusion chemotherapy as non-muscular invasive bladder cancer(P<0.05).Conclusions  The  patients with  non-muscular invasive bladder cancer taking transurethral resection for the first time are prone to recurrence because of the clinical stage of T1,tumor grade of high grade,multiple tumors and routine perfusion.Targeted intervention measures  should be taken to improve the perfusion chemotherapy method to reduce the recurrence rate.
论著

风险防范护理干预对控制冠状动脉造影术后患者血管并发症的影响

Effect of risk prevention nursing intervention on controlling vascular complications in patients after coronary angiography

:356-360
 
      目的   探讨在冠状动脉造影术后患者中应用风险防范护理干预对血管并发症的控制效果。方法   选择2022年1月—2023年6月于我院接受治疗的85例冠状动脉造影术后患者。按照随机数字表法分组,其中对照组42例给予常规护理干预,观察组43例给予风险防范护理干预,比较两组干预前后的心理状态、治疗依从性、血管并发症。结果   干预后,观察组正性情绪(PA)评分高于对照组PA评分(t=3.821,P<0.001),观察组负性情绪(NA)评分低于对照组NA评分(t=5.380,P<0.001)。与对照组比,观察组治疗依从性更好(Z=2.268,P=0.023)。观察组血管并发症总发生率低于对照组(9.30% vs 30.95%,χ 2 =6.224,P=0.013)。结论   采用风险防范护理干预,能够改善冠状动脉造影术后患者的心理状态,提高治疗依从性,并降低血管并发症总发生率。
       Objective  To explore the effect of  risk prevention nursing intervention on controlling vascular complications in patients after coronary angiography.Methods  Eighty-five patients after coronary angiography in our hospital were selected from January 2022 to June 2023.They were grouped according to the random number table.And 42 cases were divided into the control group for routine nursing intervention,and 43 cases in the observation group were given risk prevention nursing intervention.Psychological status,treatment compliance and vascular complications of the two groups were observed.Results  After the intervention,the postive affect score of the observation group was higher than that of the control group(t=3.821,P<0.001),and the negative affect score of the observation group(21.25±3.31)was lower than the score of the control group(25.35±3.70)t=5.380,P<0.001).Compared with the control group the compliance of observation group was higher(Z=2.268,P=0.023).The overall incidence of vascular complications in the observation group was lower than that in the control group(9.30% vs 30.95%,χ2=6.224,P=0.013).Conclusions  Risk prevention nursing intervention can improve the psychological status of patients after coronary angiography,improve treatment compliance,and reduce the overall incidence of vascular complications.
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