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《广州医药》编辑部
目的 探讨加强医学影像学的教育在肝胆外科本科实习教育中的应用效果。方法 选择了2021年3月—2023年12月,在广州市花都区人民医院肝胆胰疝外科实习的80名本科实习生为研究对象,依据随机数字表法将全部实习生随机分为两组,每组各40例,研究组接受强化影像教育,参照组接受传统教学,并对教学效果进行统计分析。结果 两组实习生经过两种不同教学方法后,研究组的总体成绩优于参照组,满意度比例高于参照组,组间差异具有统计学意义。结论 在肝胆外科临床实习教学中,加强影像学教育,可显著提高实习生的总体成绩,获得更高的教学满意度。
Objective To explore the application effect of strengthening medical imaging education in the undergraduate internship education of hepatobiliary surgery.Methods Eighty undergraduate interns who interned in the Department of Hepatobiliary,Pancreatic and Hernia Surgery of our hospital from March 2021 to December 2023 were selected as research subjects.Using a random number table method,the interns were evenly divided into two groups,with 40 interns in each group.The experimental group received enhanced imaging education,while the control group received traditional teaching.The teaching effects were statistically analyzed.Results After undergoing two different teaching methods,the experimental group had better overall scores than the control group,and a higher satisfaction rate than the control group ,with statistically significant differences between the groups.Conclusions Strengthening imaging education in clinical internship teaching of hepatobiliary surgery can significantly improve interns’ overall scores and achieve higher teaching satisfaction,indicating its value for promotion.
目的 探讨低浓度罗哌卡因行超声引导下髋关节囊周围神经(PENG)阻滞联合椎管内麻醉对衰弱患者髋关节手术的应用优势。方法 选择行髋关节手术的衰弱患者76例,随机分为两组,A 组(38例)行PENG阻滞联合椎管内麻醉,C 组(38例)行椎管内麻醉。比较两组入室(T0)、摆放体位时(T1)、术后6 h(T2)、术后12 h(T3)、术后24 h(T4)静息和活动状态的数字等级评定量表(NRS)疼痛评分;术后非甾体抗炎药及阿片类药物补救次数;术后 6 h、24 h患侧股四头肌徒手肌力分级(MMT);首次下床活动时间、住院时间。结果 A组T1~T4时刻静息状态NRS疼痛评分分别为2(1,3)分、1(1,2)分、2(1,2)分、3(2,4)分均低于C组的5(4,7)分、4(3,5)分、5(3,6)分、4(2,6)分,比较差异有统计学意义(均P<0.001);A组T1~T4时刻活动状态NRS疼痛评分分别为5(4,7)分、3(2,4)分、4(3,5)分、6(4,7)分均低于C组的10(9,10)分、8(6,9)分、8(7,9)分、9(8,10)分,比较差异有统计学意义(均P<0.001)。A组在T1~T4时的静息状态NRS疼痛评分低于T0时的(均P<0.01);C组在T1~T4时的静息状态NRS疼痛评分低于T0时的(均P<0.05);A组在T1~T4时的活动状态NRS疼痛评分均低于T0时的(均P<0.001);C组在T1、T2时的活动状态NRS疼痛评分均低于T0时的(均P<0.01)。A组术后非甾体抗炎药及额外阿片类药物补救次数为4(0,8)、2(0,3)次,均低于C组的15(7,19)、5(3,7)次,比较差异有统计学意义(均P<0.001)。两组术后 6 h和24 h患侧股四头肌MMT分级、首次下床活动时间和住院时间比较差异无统计学意义(P>0.05)。结论 低浓度罗哌卡因PENG阻滞可以有效减轻衰弱患者髋关节手术术后疼痛,不影响其术后下肢肌力。
Objective To explore the application advantages of low-concentration ropivacaine for ultrasound-guided pericapsular nerve group(PENG)block combined with spinal-epidural anesthesia in hip joint surgery for frail patients.Methods Seventy-six frail patients undergoing hip surgery were randomly divided into two groups:Group A(38 cases)received PENG block combined with intraspinal anesthesia,while Group C(38 cases)received only intraspinal anesthesia.The numerical rating scale(NRS)pain scores of resting and active states were compared between the two groups at the time of entering the room(T0),placing the position(T1),6 hours after surgery(T2),12 hours after surgery(T3),and 24 hours after surgery(T4).Postoperative non-steroidal drugs and opioids remedy times,muscle strength grading(MMT)of quadriceps femoris at 6 hours and 24 hours after operation,and the first time out of bed activity time,hospitalization time were also compared.Results The resting NRS pain scores at T1-T4 in Group A were 2(1,3),1(1,2),2(1,2)and 3(2,4),respectively,which were lower than 5(4,7),4(3,5),5(3,6)and 4(2,6)in Group C,and the difference was statistically significant(all P<0.001).The NRS pain scores at T1-T4 in Group A were 5(4,7),3(2,4),4(3,5)and 6(4,7),respectively,which were lower than 10(9,10),8(6,9),8(7,9)and 9(8,10)in Group C,and the difference was statistically significant(all P<0.001).The resting NRS pain score of Group A at T1-T4 was lower than that at T0(all P<0.01);the resting NRS pain score of Group C at T1-T4 was lower than that at T0(all P<0.05).The NRS pain scores at T1-T4 in Group A were lower than those at T0(all P<0.001);the NRS pain scores at T1 and T2 in Group C were lower than those at T0(all P<0.01).The number of postoperative non-steroidal drugs and additional opioids in group A(4[0,8],2[0,3])was lower than that in Group C(15[7,19],5[3,7]),and the difference was statistically significant(all P>0.001).There was no significant difference in the MMT grade of the affected quadriceps femoris at 6 h and 24 h after operation,the first time of getting out of bed and the number of days of hospitalization between the two groups(P>0.05).Conclusions Low concentration ropivacaine PENG block can effectively reduce the postoperative pain of hip joint surgery in frail patients without affecting the postoperative lower extremity muscle strength.
目的 探究单髁膝关节置换(UKA)联合注射布比卡因脂质体治疗老年孤立性内侧间室骨关节炎(OA)的效果,并分析其对患者术后长效镇痛的作用。方法 前瞻性选取2023年11月—2025年11月期间收治的80例老年孤立性内侧间室OA患者,分为对照组与研究组,各40例。两组患者均接受UKA手术治疗,研究组在术中于相同部位注射布比卡因脂质体,对照组于术中关节周围注射等体积的生理盐水混合物。比较两组术后疼痛强度,镇痛药物消耗与需求,早期膝关节功能恢复情况、早期膝关节功能,以及两组不良反应发生率。结果 研究组术后6 h、12 h、24 h及48 h VAS评分均低于对照组,术后48 h内,研究组中重度疼痛发生率较对照组低(P<0.05);研究组术后首次请求镇痛的时间晚于对照组,48 h内曲马多总消耗量及补救镇痛需求率均较对照组低(P<0.05);研究组在术后24 h、48 h、72 h的膝关节主动活动度较对照组大,研究组首次直腿抬高时间、术后下地行走时间及住院时间均较对照组短(P<0.05);术前两组膝关节协会评分(KSS)和牛津膝关节评分(OKS)评分无差异(P>0.05)。术后1周,两组评分均改善,且研究组优于对照组(P<0.05);两组不良反应发生率无差异(P>0.05)。结论 UKA术中联合应用布比卡因脂质体,能安全、有效地为老年孤立性内侧间室OA患者提供长效术后镇痛。且该方案不仅能显著减轻患者早期疼痛、减少阿片类药物依赖,更能有效促进膝关节早期功能恢复、缩短住院时间,并为患者获得更优的早膝关节功能奠定基础。
Objective To investigate the efficacy of unicompartmental knee arthroplasty(UKA) combined with injection of bupivacaine liposomes in the treatment of elderly isolated medial compartment osteoarthritis(OA),and analyze its long-term analgesic effect on patients after surgery.Methods A prospective study was conducted on 80 elderly patients with isolated medial compartment OA admitted between November 2023 and November 2025.They were divided into a control group and a study group,with 40 patients in each group.Both groups of patients received UKA treatment.The study group received injection of bupivacaine liposomes at the same site during surgery,while the control group received injection of an equal volume of physiological saline mixture around the joints during surgery.Postoperative pain intensity,analgesic drug consumption and demand,early knee joint function recovery,early knee joint function were compared between two groups,and the incidence of adverse reactions was compared between the two groups.Results The study group had lower VAS scores at 6 h,12 h,24 h,and 48 h postoperatively compared to the control group.Within 48 hours after surgery,the incidence of moderate to severe pain in the study group was lower than that in the control group(P<0.05).The time to first postoperative analgesic request in the study group was later than that in the control group,and the total tramadol consumption and the need for analgesia within 48 hours were lower(P<0.05).The active range of motion of the knee at 24 h,48 h,and 72 h postoperatively was greater in the study group compared to the control group.Additionally,the time to first straight leg raise,time to ambulation,and length of hospital stay were all shorter in the study group(P<0.05).Preoperatively,there were no differences between the two groups in the Knee Society Score(KSS) and the Oxford Knee Score(OKS)(P>0.05).One week postoperatively,both groups showed improved scores,with the study group showing greater improvement than the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions The combined use of bupivacaine liposomes during UKA can provide safe and effective long-term postoperative analgesia for elderly patients with isolated medial compartment OA.And this plan not only reduces early pain and opioid dependence in patients,but also effectively promotes early knee joint function recovery,shortens hospitalization time,and lays a solid foundation for patients to achieve better early knee joint function.
目的 探讨胸部肿瘤患者手术后早期排痰的效果,降低肺部并发症的发生率。方法 选择2024年6月—2025年7月在本院进行胸部肿瘤切除的60例术后患者作为研究对象。采用非同期回顾对照设计,以不同时间段病例分组,分为对照组(n=30)和观察组(n=30)。两组胸部手术后患者均给予常规围术期护理,观察组胸部手术后患者增加早期排痰护理。统计两组排痰效果[咳痰难度、血氧饱和度(SPO2)]变化、疼痛评分,并统计两组肺部相关并发症及住院时间进行比较。结果 观察组患者术后的SPO2水平高于对照组(P<0.05),咳痰难度评分低于对照组患者(P<0.05)。干预后第B、C时间点观察组患者的疼痛评分均低于对照组(P<0.05)。观察组住院时间短于对照组(P<0.05),胸部并发症总发生率低于对照组(P<0.05),满意度高于对照组(P<0.05)。结论 胸部肿瘤术后早期排痰有助于促进术后患者排痰,减少肺部相关发症,缩短住院时间。
Objective To investigate the efficacy of early expectoration management in reducing pulmonary complications for patients following thoracic tumor surgery.Methods Sixty patients undergoing thoracic tumor resection at our hospital between 2024 and 2025 were enrolled.A non-concurrent retrospective control design was adopted.Cases were grouped according to different time periods,divided into a control group(n=30)and an observation group(n=30).The control group received standard perioperative care,while the observation group received additional early expectoration nursing interventions.Outcome measures included expectoration efficacy(assessed by cough difficulty score and oxygen saturation[SpO2]),pain scores,incidence of pulmonary complications,and hospital stay duration.Results Postoperative SpO2 levels were higher in the observation group than in the control group (P<0.05),while cough difficulty scores were significantly lower(P<0.05).At time points B and C after the intervention,the pain scores of patients in the observation group were lower than those in the control group(P<0.05).The observation group demonstrated a significantly shorter hospital stay(P<0.05),a lower overall incidence of thoracic complications(P<0.05),and higher patient satisfaction than the control group(P<0.05).Conclusions Implementing early expectoration protocols after thoracic tumor surgery facilitates sputum clearance can reduce pulmonary complications,and shorten hospitalization time.
目的 探究四子散中药封包药熨在股骨骨折术后疼痛及肿胀中的临床疗效及安全性。方法 选取2024年6月—2025年5月婺源县人民医院骨科收治的60例股骨骨折术后患者, 随机分为观察组(30例,常规治疗+四子散中药封包药熨)与对照组(30例,常规治疗)。比较两组治疗前后疼痛评分(NRS-11)、肿胀程度评分、C反应蛋白(CRP)、白细胞介素-6(IL-6)水平及不良事件发生率。结果 治疗前两组患者疼痛、肿胀评分、CRP、IL-6水平比较差异无统计学意义(P>0.05); 治疗1周后,观察组疼痛评分为(2.11±0.48)分、肿胀程度为(0.35±0.43)度、CRP为(12.23±3.12)mg/L、IL-6为(16.03±4.01)ng/L,均低于对照组的(3.54±0.56)分、(1.04±0.58)度、(24.31±4.51)mg/L、(23.19±6.75)ng/L,差异有统计学意义(P<0.001)。观察组与对照组均无发生不良事件。结论 四子散中药封包药熨可缓解股骨骨折术后疼痛及肿胀,安全性良好。
Objective To explore the clinical efficacy and safety of Sizi powder pack hot compress in the treatment of pain and swelling after femoral fracture surgery.Methods From June 2024 to May 2025, 60 patients after femoral fracture surgery were admitted to the Orthopedics Department of Wuyuan County People's Hospital and randomly divided into observation group(30 cases, conventional treatment+Sizi power pack hot compress)and control group(30 cases, conventional treatment). The pain score(NRS-11), swelling score, CRP,IL-6 levels and incidence of adverse events before and after treatment were compared between the two groups.Results There was no significant difference in pain and swelling scores between the two groups before treatment(P>0.05).After 1 week of treatment, the pain score(2.11±0.48), swelling score(0.35±0.43), CRP(12.23±3.12 mg/L), IL-6(16.03±4.01 ng/L)levels in the observation group were significantly lower than those in the control group(3.54±0.56, 1.04±0.58, 24.31±4.51 mg/L, 16.03+4.01 ng/L), and the difference was statistically significant(P<0.001).There were no adverse events in the observation group or the control group.Conclusions Sizi power pack hot compress can significantly alleviate the pain and swelling after femoral fracture surgery,and with good safety.
吲哚菁绿(ICG)荧光成像技术基于ICG独特的代谢特性及近红外光激发特性, 通过动态荧光显影成像为手术提供精准导航, 其在肝胆胰外科领域展现出重要的应用价值。随着多版国内外指南的迭代更新, ICG荧光导航技术已被确立为肝胆胰外科手术的重要辅助手段, 其安全性和有效性得到充分验证。文章就ICG荧光成像技术的原理、在肝胆胰外科应用中的现状、在临床应用中面临的问题以及其应用展望展开综述。
Based on the unique metabolic properties and near-infrared light excitation characteristics of indocyanine green(ICG), the ICG fluorescence imaging technology provides dynamic fluorescence imaging for precise surgical navigation.This technology has demonstrated significant value in hepatobiliary and pancreatic surgery.With iterative updates to international and domestic guidelines, ICG-based fluorescence navigation has been established as an essential adjunctive tool in hepatopancreaticobiliary procedures, with its safety and efficacy validated through extensive clinical research.This review systematically explores the underlying principles of ICG fluorescence imaging, its current applications in liver, biliary, and pancreatic surgeries, the challenges encountered in clinical practice, and future directions for technological optimization and clinical translation
主动脉外科已走过70年的辉煌岁月,现有诊疗体系已基本解决“挽救患者生命”的重要时代议题。如今,新一轮科技革命悄然来临,我国主动脉外科广大同仁应主动转变以“量”取胜的传统观念,寻找学科内容不足,明确诊疗环节短板,提炼问题底层逻辑,以“质”换空间,扩展学科边界。学科发展更应秉持开放包容之心态,坚持守正创新之原则,借助不同学科技术优势,努力解决目前诊疗活动各环节中仍存在的问题及争议点,为我国广大人民群众提供精细化的诊疗服务。
For the past 70 years of aortic surgery,the current diagnosis and treatment strategies have generally solved the important issue of “saving lives”.Nowadays,the new scientific and technological revolution is coming.The practitioners in aortic surgery should change the traditional perception and look for the insufficiency and the shortcomings of diagnosis and treatment,which finally expand the boundaries of the discipline.Moreover,the discipline development shall be more open-minded and persist in innovation.We should take the advantages of different discipline technologies,and strive to solve the current issues and controversies remaining in diagnosis and treatment toward providing refined services for the public.
目的 探讨与分析全面护理联合细节干预在创伤骨科手术质量及康复中应用价值。方法 选择2022年1月—2023年1月在福建省立医院骨科进行创伤骨科手术患者120例为研究对象,用随机数字表法分组,分为常规组、联合组,各纳入60例患者。前者进行常规护理,后者在前者基础上开展全面护理联合细节干预,对两组患者术后恢复情况进行观察比较。结果 在围术期指标方面,联合组手术时间、术中出血量、术后首次下床活动时间、术后住院时间与常规组相比减少(P<0.05)。联合组术后1 d、术后3 d、术后7 d、术后14 d的疼痛VAS评分与常规组相比减少(P<0.05)。联合组术后14 d的护理总满意度为100.00%,常规组为83.33%,联合组与常规组相比明显提高(P<0.05)。联合组术后14 d的社会关系、心理关系、生理关系等生活质量评分均高于常规组(P<0.05)。结论 全面护理联合细节干预在创伤骨科手术患者的应用促进患者康复,能持续缓解患者的疼痛状况,提高患者的护理满意度与生活质量。
Objective To explore and analyze the application value of comprehensive nursing combined with detailed intervention in the quality and rehabilitation of orthopedic trauma surgery.Methods From January 2022 to January 2023,120 cases of patients who underwent trauma orthopedic surgery in the Department of Orthopedic Surgery of Fujian Provincial Hospital were selected as the research subjects.And the randomized numerical table method was taken to operate in groups,which were divided into the conventional group and the combined group,and 60 patients were included in each group.The former group recieved conventional nursing care,and the latter group recieved comprehensive nursing care combined with detail intervention on its basis to observe and compare the postoperative recovery of patients in the two groups.Results In terms of perioperative indicators,the operation time,intraoperative bleeding,time to first postoperative bed movement and postoperative hospitalization time were significantly reduced in the combined group compared with the conventional group(P<0.05).The pain VAS scores of the combination group were significantly reduced compared to the conventional group at 1 day,3 days,7 days and 14 days after surgery(P<0.05).The total satisfaction rate of postoperative care in the combination group at 14 days was 100.00%,while in the conventional group it was 83.33%.The combination group showed there were significant improvements compared to the conventional group(P<0.05).The social,psychological and physiological quality of life scores of the combination group were significantly higher than those of the conventional group 14 days after surgery(P<0.05).Conclusions The application of comprehensive nursing combined with detailed intervention in orthopedic trauma surgery patients can promote their recovery,continuously alleviate their pain status and improve their nursing satisfaction and quality of life.
肥胖是一种以慢性低度炎症为特征的进展性疾病,与多种代谢性疾病的发生、发展密切相关。脂肪组织作为一种内分泌和免疫器官,可分泌多种生物活性物质及炎症因子,参与肥胖患者体内的代谢过程。减重手术是治疗病态性肥胖及相关代谢性疾病的有效方法之一,能够调节机体内的炎症反应、有效改善代谢状态。但减重手术对于炎症因子的作用如何,目前国内外的文献证据仍有争议。本文将系统阐述肥胖与代谢性炎症的关系以及减重手术对炎症因子的影响,旨在为肥胖代谢外科的诊疗过程提供参考。
Obesity is a progressive disease characterized by chronic low-grade inflammation,which is closely related to the occurrence and development of a variety of metabolic diseases.As an endocrine and immune organ,adipose tissue can secrete a variety of bioactive substances and inflammatory factors,which participate in the metabolic process of obese patients.Bariatric surgery is one of the effective methods for the treatment of morbid obesity and related metabolic diseases,which can regulate the inflammatory response in the machine and effectively improve the metabolic state.However,the effect of bariatric surgery on inflammatory factors is still controversial at home and abroad.This article will systematically explain the relationship between obesity and metabolic inflammation and the effect of bariatric surgery on inflammatory factors,aiming to provide a reference for the diagnosis and treatment process of bariatric surgery.
腹腔镜手术后除躯体创伤疼痛,部分患者还可能经历痛苦的术后内脏痛,不仅使患者术后体验不佳,疼痛应激甚至可能加重机体的内环境紊乱,不利于患者的术后康复。内脏痛是来源于内脏器官和组织的疼痛,其产生与脏器的平滑肌痉挛、扩张、缺血、化学炎症刺激等密切相关。在这个过程中,许多离子通道和受体在调节内脏伤害性刺激信号的传导上发挥作用。目前,临床上术后镇痛治疗方案多样,但如何针对性地控制术后内脏痛是临床医生需要面对和解决的问题。为此,该文对腹腔镜术后内脏痛发生的相关机制、内脏感觉的神经传导及临床特征、治疗进展进行综述。
In addition to physical trauma,patients undergoing laparoscopic surgery may also experience postoperative visceral pain.This pain not only impacts the patient's postoperative experience,but can also worsen the body's internal environment and hinder recovery.Visceral pain originates from internal organs and tissues.It is closely related to smooth muscle spasms,dilations,ischemia,and chemical inflammatory stimulation of organs.In this process,numerous ion channels and receptors regulate the transmission of visceral nociceptive stimulus signals.At present,there are multiple clinical treatment options available for postoperative pain management.However,clinicians must overcome the challenge of controlling postoperative visceral pain.This article provides a review of the relevant mechanisms of visceral pain following laparoscopic surgery,the neural conduction of visceral sensation,clinical characteristics and treatment advancements.