目的 分析2016—2024年宜春市5岁以下儿童死亡水平、死因构成、县区分布特征及变化趋势，为制定儿童健康干预策略提供依据。方法 回顾性收集2016—2024年宜春市5岁以下儿童死亡监测资料，统计各年度新生儿、婴儿及5岁以下儿童死亡率，分析死因构成比、顺位变化及县区分布特征，采用线性趋势χ2检验分析死亡率年度变化趋势。结果 2016—2024年宜春市各年龄段儿童死亡率均呈下降趋势（均P＜0.05），新生儿、婴儿、5岁以下儿童9年平均死亡率分别为1.35‰、2.62‰、5.02‰，较2016年分别下降26.79%、43.55%、43.06%。死因顺位整体呈现小幅变迁，肺炎占比逐步下降，溺水、意外窒息等意外伤害相关死因顺位持续前移。各县区死亡率存在差异，高死亡率县区集中在袁州区、奉新县，低死亡率县区以铜鼓县为主。结论 2016—2024年宜春市5岁以下儿童死亡率呈下降趋势，但意外伤害已成为主要死因，县区差异客观存在。应重点加强意外伤害预防工作，针对高死亡率县区实施差异化干预。

目的 探讨紫芪补肾汤联合达格列净治疗脾肾阳虚型糖尿病肾病（DKD）患者的临床疗效，并分析其对糖代谢、肾功能的影响。方法 选取2024年9月～2025年9月于本院就诊的106例DKD患者为研究对象，按照随机数字表法将其分为对照组、研究组，各53例。对照组予以达格列净治疗，研究组予以紫芪补肾汤联合达格列净治疗，连续治疗2个月。统计对比两组临床疗效、不良反应及治疗前后中医证候积分、血糖及糖代谢指标[空腹血糖（FPG）、餐后2 h血糖（2 h PG）、糖化血红蛋白（HbA1c）、糖原合酶激酶-3β（GSK-3β）、缺氧诱导因子-1α（HIF-1α）]、肾功能相关指标[血尿素氮（BUN）、血肌酐（SCr）、尿微量白蛋白排泄率（UAER）、估算的肾小球滤过率（eGFR）、同型半胱氨酸（Hcy）、胱抑素C（CysC）、碳水化合物反应元件结合蛋白（ChREBP）]、炎症因子[肿瘤坏死因子-α（TNF-α）、白细胞介素-1β（IL-1β）、肿瘤坏死因子1型受体（TNFR1）、趋化因子配体9（CXCL9）]、血管内皮功能[血管生成抑制蛋白-1（VASH-1）、血管内皮生长因子（VEGF）、内皮素-1（ET-1）、一氧化氮（NO）、血栓素B2（TXB2）]。结果 研究组总有效率为90.57%，明显高于对照组的73.58%（P＜0.05）；研究组治疗后中医证候积分低于对照组（P＜0.05）；研究组治疗后FPG、2 h PG、HbA1c、GSK-3β、HIF-1α水平低于对照组（P＜0.05）；研究组治疗后BUN、SCr、UAER、Hcy、CysC、ChREBP水平低于对照组，eGFR高于对照组（P＜0.05）；研究组治疗后血清TNF-α、IL-1β、TNFR1、CXCL9水平低于对照组（P＜0.05）；研究组治疗后VASH-1、NO水平高于对照组，VEGF、ET-1、TXB2水平低于对照组（P＜0.05）；两组不良反应比较无明显差异（P＞0.05）。结论 紫芪补肾汤联合达格列净治疗DKD患者的疗效显著，可降低血糖水平，改善肾功能，抑制炎症反应，减轻血管内皮损伤，且具有一定安全性。

目的 比较白内障超声乳化吸除术（Phaco）+房角分离术与Phaco+小梁切除术治疗急性原发性闭角型青光眼（APACG）合并白内障的临床价值。方法 回顾性分析2022年1月至2025年1月我院200例APACG合并白内障患者临床资料，根据手术方式分为小梁切除组（Phaco+小梁切除术）与房角分离组（Phaco+房角分离术），每组100例（200眼）。比较两组眼压、视力[最佳矫正视力（BCVA）]、中央前房深度、视盘血流密度[整体视盘血流密度（wiVD）、视盘内血流密度（diVD）]、生活质量[视功能相关生活质量量表-25（NEI-VFQ-25）]及并发症情况。结论 术后1周、1个月、3个月，房角分离组眼压低于小梁切除组，BCVA、中央前房深度大于小梁切除组，wiVD、diVD高于小梁切除组（P＜0.05）；术后1个月，房角分离组NEI-VFQ-25评分高于小梁切除组（P＜0.05），术后3月两组NEI-VFQ-25评分比较无显著差异（P＞0.05）；房角分离组并发症总发生率（6.50%）低于小梁切除组（13.00%）（P＜0.05）。结论 与Phaco+小梁切除术相比，Phaco+房角分离术治疗APACG合并白内障患者能有效控制眼压，增加前房深度，改善视盘血流循环，恢复患者视力，提高生活质量，减少并发症发生率。

Objective To compare the clinical efficacy of phacoemulsification (Phaco) combined with goniosynechialysis and phacoemulsification combined with trabeculectomy in the treatment of acute primary angle-closure glaucoma (APACG) complicated with cataract. Methods The clinical data of 200 patients with APACG complicated with cataract treated in our hospital from January 2022 to January 2025 were retrospectively analyzed. According to surgical procedures, the patients were divided into trabeculectomy group (Phaco combined with trabeculectomy) and goniosynechialysis group (Phaco combined with goniosynechialysis), with 100 patients (200 eyes) in each group. Intraocular pressure, visual acuity [best corrected visual acuity (BCVA)], central anterior chamber depth, optic disc vessel density [whole-image optic disc vessel density (wiVD), disc-inside vessel density (diVD)], quality of life [25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25)] and complications were compared between the two groups. Results At 1 week, 1 month and 3 months after surgery, the goniosynechialysis group had lower intraocular pressure, better BCVA, deeper central anterior chamber depth, and higher wiVD and diVD than the trabeculectomy group (P<0.05). One month postoperatively, the NEI-VFQ-25 score of the goniosynechialysis group was significantly higher than that of the trabeculectomy group (P<0.05), while no significant difference was observed between the two groups at 3 months after surgery (P>0.05). The overall incidence of complications in the goniosynechialysis group was 6.50%, which was lower than 13.00% in the trabeculectomy group (P<0.05). Conclusion Compared with phacoemulsification combined with trabeculectomy, phacoemulsification combined with goniosynechialysis can effectively control intraocular pressure, increase anterior chamber depth, improve optic disc blood circulation, restore visual acuity, enhance quality of life and reduce the incidence of complications in patients with APACG complicated with cataract.

摘要：目的 分析2022—2024年深圳市福田区危重症孕产妇不同亚组（不同并发症/合并症）的流行病学特征、病因构成及相关因素，为优化区域孕产妇健康管理提供依据。方法 基于福田区危重症孕产妇监测网络，对2022年1月1日至2024年12月31日期间107921例孕产妇个案资料进行回顾性描述性分析，采用描述性流行病学方法及卡方检验分析不同因素与危重症主要并发症的关联。结果 深圳市福田区3年间危重症孕产妇共729例，总体发生率为6.75‰。各年度发生率分别为2022年6.67‰、2023年7.38‰和2024年6.33‰。危重症孕产妇中，≥35岁者占33.7%，本科及以上学历者占53.8%。初检妊娠风险评级为黄色者占比最高（41.98%），高危者占21.9%。最常见并发症为产后出血（43.89%），其次为宫缩乏力（17.28%）、前置胎盘（16.59%）、子痫/子痫前期（14.67%）和胎盘植入（13.99%）。血液系统疾病为最常见合并症（57.75%），内分泌系统疾病次之（24.42%）。单因素分析显示，产后出血的发生与高龄、产检次数不足5次、经产妇身份存在统计学关联（均P<0.05）；前置胎盘的发生与高龄、低学历、非汉族、初检高危评级、产检不足5次、经产存在统计学关联（均P<0.05）。结论 深圳市福田区危重症孕产妇发生率约为6.75‰，产后出血和前置胎盘为主要并发症。单因素分析显示，高龄、产检不足、初检高危分级及经产与上述主要并发症的发生相关。应加强动态妊娠风险管理和多学科协作，完善产科早期预警体系，以降低危重症孕产妇发生率，提高母婴安全水平。

Abstract: Objective To analyze the epidemiological characteristics, etiology composition, and related factors of critically ill pregnant women in Futian District, Shenzhen, from 2022 to 2024. Methods Based on the surveillance network, a retrospective descriptive analysis was conducted on 107,921 pregnant women. Chi-square tests were used to analyze the association between different factors and major complications. Results A total of 729 critically ill pregnant women were identified (overall incidence 6.75‰).??The most common complication was postpartum hemorrhage (43.89%), followed by uterine atony (17.28%), placenta previa (16.59%), eclampsia/preeclampsia (14.67%), and placenta accreta (13.99%). Univariate analysis showed that postpartum hemorrhage was statistically associated with advanced age, <5 antenatal visits, and multiparity (all P<0.05). Placenta previa was statistically associated with advanced age, low education level, non-Han ethnicity, high-risk initial assessment, <5 antenatal visits, and multiparity (all P<0.05). Conclusion The incidence of critically ill pregnant women in Futian District is approximately 6.75‰. Univariate analysis suggested that advanced age, insufficient antenatal visits, high-risk classification, and multiparity were associated with the main complications. Dynamic risk management and multidisciplinary collaboration should be strengthened.

目的 探讨膀胱镜在血尿患者膀胱病变诊断中的应用价值，并比较其与超声、CT尿路造影（CTU）、尿液细胞学的诊断效能差异，为临床精准诊疗提供参考。方法 回顾性选取在2020年6月至2025年6月期间本院收治的100例血尿患者作为研究对象，所有患者均 接受膀胱镜检查，以病理检查结果为金标准，分析病变类型分布情况；统计膀胱镜的诊断准确率、灵敏度、特异度；并比较4种检查方法对膀胱肿瘤的检出效能；记录并发症发生情况。结果 100例血尿患者经病理检查确诊：膀胱病变68例，其中膀胱肿瘤23例、膀胱炎26例、膀胱结石12例、膀胱息肉7例；非膀胱源性血尿32例。在膀胱肿瘤检出方面：超声灵敏度34.78%（8/23）、CTU灵敏度47.83%（11/23）、尿液细胞学灵敏度26.09%（6/23），而膀胱镜灵敏度为95.65%（22/23）。肉眼血尿组的膀胱病变检出率和膀胱肿瘤检出率均显著高于镜下血尿组（P<0.05）。经膀胱镜检查诊断：膀胱病变71例，阳性65例，阴性6例；非膀胱病变29例，阴性26例，阳性3例。膀胱镜的灵敏度、特异度和准确度分别为95.59%、81.25%、91.00%；膀胱镜与病理检查的一致性良好（kappa=0.894）。5例患者出现轻微血尿，3例患者出现尿道刺激症状，均在1～2天内自行缓解。无严重感染、膀胱穿孔等严重并发症发生。结论 膀胱镜检查对膀胱病变具有极高的诊断价值，其灵敏度显著优于超声、CTU及尿液细胞学。对于肉眼血尿患者，膀胱镜检查指征明确；对于镜下血尿患者，需结合危险因素综合评估检查必要性，避免过度医疗。

Objective This study explores the application value of cystoscopy in the diagnosis of bladder lesions in patients with hematuria, and compares its diagnostic efficacy with that of ultrasound, CT urography (CTU), and urine cytology, aiming to provide a reference for clinical precise diagnosis. Methods: A total of 100 patients with hematuria admitted to our hospital from June 2020 to June 2025 were retrospectively selected as the research subjects. All patients underwent cystoscopy. Taking the pathological examination results as the gold standard, the distribution of lesion types was analyzed, and the diagnostic accuracy, sensitivity, specificity of cystoscopy. Compare the detection efficacy of the four examination methods for bladder tumors; record the occurrence of complications. Results: Among 100 patients with hematuria, pathological examination confirmed that 68 cases had bladder lesions, including 23 cases of bladder tumors, 26 cases of cystitis, 12 cases of bladder stones, and 7 cases of bladder polyps. There were 32 cases of non-bladder origin hematuria. In terms of bladder tumor detection: the sensitivity of ultrasound was 34.78% (8/23), that of CTU was 47.83% (11/23), that of urine cytology was 26.09% (6/23), and that of cystoscopy was 95.65% (22/23). The detection rates of bladder lesions and bladder tumors in the group with gross hematuria were significantly higher than those in the group with microscopic hematuria (P < 0.05). Diagnosis by cystoscopy: 71 cases of bladder lesions, 65 positive cases and 6 negative cases. There were 29 cases of non-bladder lesions, including 26 negative cases and 3 positive cases. The sensitivity, specificity and accuracy of cystoscopy were 95.59%, 81.25% and 91.00% respectively. The consistency between cystoscopy and pathological examination was good (kappa=0.894). Five patients presented with mild hematuria and three patients had urethral irritation symptoms, all of which relieved spontaneously within 1 to 2 days. No serious complications such as severe infection or bladder perforation occurred. Conclusion: Cystoscopy has extremely high diagnostic value for bladder lesions, with its sensitivity significantly superior to ultrasound, CTU and urine cytology. For patients with gross hematuria, the indication for cystoscopy is clear; for those with microscopic hematuria, the necessity of the examination should be comprehensively evaluated based on risk factors to avoid excessive medical treatment.

目的 分析乙型肝炎病毒（HBV）感染患者并发2型糖尿病（T2DM）相关风险因素。方法 研究收集2024年1月~2025年5月期间，于周口市传染病医院（周口市结核病防治所、周口市第五人民医院）接受治疗的HBV感染患者临床资料，共纳入患者95例，根据HBV感染后是否并发T2DM分组，合并T2DM患者纳入并发组（n=21），非合并T2DM患者纳入对照组（n=74），比较两组患者基线资料及实验室检查数据，逻辑回归分析HBV感染患者并发T2DM风险因素。结果 并发组年龄、体重指数（BMI）、甘油三酯（TG）高于对照组（P＜0.05），年龄≥45岁、BMI肥胖、HBV感染时间≥6个月、TG≥1.7mmol/L、吸烟、乙型肝炎表面抗原（HBsAg）阳性及纤维化-4（FIB-4）指数≥2.67例数占比高于对照组（P＜0.05）。年龄≥45岁[OR=21.599（95%CI：2.875-162.262）]、BMI（肥胖）[OR=16.729（95%CI：1.443-193.981）]、HBV感染时间≥6个月[OR=6.199（95%CI：1.101-34.904）]、吸烟[OR=9.429（95%CI：1.344-66.141）]、TG≥1.7mmol/L[OR=71.834（95%CI：7.060-730.897）]是HBV感染患者并发T2DM危险因素（P＜0.05）。结论 HBV感染患者并发T2DM受人口学特征年龄、BMI、临床病程HBV感染时间、共病血脂异常及生活方式吸烟的共同影响。

Abstract: Objective To analyze risk factors associated with the development of type 2 diabetes mellitus (T2DM) in patients with hepatitis B virus (HBV) infection. Methods Clinical data were collected from HBV-infected patients treated at the Zhoukou City Infectious Disease Hospital (Zhoukou City Tuberculosis Prevention and Control Institute)between January 2024 and May 2025. A total of 95 patients were included in the study, Patients were grouped based on the presence or absence of T2DM following HBV infection. Patients with T2DM were included in the T2DM group (n=21), while those without T2DM were included in the control group (n=74). Baseline characteristics and laboratory test data were compared between the two groups, and logistic regression analysis was performed to identify factors associated with the development of T2DM in HBV-infected patients. Results The age, body mass index (BMI), and triglycerides (TG) in the intervention group were higher than those in the control group (P < 0.05); The proportion of cases with age ≥45 years, obese BMI, HBV infection duration ≥6 months, TG ≥1.7 mmol/L, smoking, hepatitis B surface antigen (HBsAg) positivity, and a FIB-4 score ≥2.67 was higher than that in the control group (P < 0.05). Age ≥ 45 years [OR = 21.599 (95% CI: 2.875–162.262)], BMI (obesity) [OR = 16.729 (95% CI: 1.443–193.981)], duration of HBV infection ≥ 6 months [OR = 6.199 (95% CI: 1.101–34.904)], smoking [OR=9.429 (95% CI: 1.344–66.141)], and TG ≥ 1.7 mmol/L [OR=71.834 (95% CI: 7.060–730.897)] were risk factors for T2DM in patients with HBV infection (P < 0.05). Conclusion The development of T2DM in patients with HBV infection is influenced by a combination of demographic factors (age and BMI), clinical course (duration of HBV infection), comorbid dyslipidemia, and lifestyle factors (smoking).

摘要 目的 分析固定（FB）和活动平台（MB）单髁置换术（UKA）在膝关节内侧间室骨关节炎早期阶段的临床效果与影像学差异，以指导临床假体选择。 方法 本研究回顾性纳入41例确诊为单侧膝关节内侧间室骨关节炎的患者，按照假体类型分为两组：FB组（20例，使用春立XG假体）和MB组（21例，使用春立XK假体）。分别在术前、术后及随访终点统计膝关节屈伸活动范围（ROM）、VAS 疼痛评分、美国特种外科医院膝关节评分（HSS ）；测量并比较股胫角（FTA）、胫骨假体内外翻角（TCVA）、胫骨假体后倾角（TCPSA）；记录围手术期指标及并发症情况。 结果 两组患者术后ROM、VAS、HSS 评分均较术前显著改善（P均<0.0001）；末次随访时固定平台组 VAS 评分显著低于活动平台组（P<0.05），而两组间的ROM、HSS 评分无统计学差异（均 P>0.05）。两组术后 FTA、TCVA、TCPSA 均恢复至理想范围，组间均无统计学差异（均 P>0.05）。固定平台组手术时间更短（P<0.05），两组均无严重并发症，假体生存率均为 100%。 结论 活动平台与固定平台单髁置换术均可显著改善膝关节内侧间室骨关节炎患者疼痛、活动度及功能，下肢力线恢复效果相当；固定平台假体在疼痛控制与手术便捷性方面更具优势，临床可根据患者情况与术者经验个体化选择。 关键词 单髁置换术；活动平台假体；固定平台假体；骨关节炎；并发症

Abstract Objective To investigate the early clinical outcomes and radiological differences between fixed-bearing (FB) and mobile-bearing (MB) unicompartmental knee arthroplasty (UKA) in the treatment of medial compartment knee osteoarthritis (OA), and to provide evidence for clinical prosthesis selection. Methods Clinical data of 41 patients with unilateral medial compartment knee OA were retrospectively analyzed. The FB group comprised 20 patients (using Chunli XG prosthesis), and the MB group comprised 21 patients (using Chunli XK prosthesis). Knee range of motion (ROM), Visual Analogue Scale (VAS) pain score, and Hospital for Special Surgery (HSS) knee score were compared between the two groups preoperatively, postoperatively, and at the final follow-up. Femorotibial angle (FTA), tibial component valgus angle (TCVA), and tibial component posterior slope angle (TCPSA) were measured and compared. Perioperative indicators and complications were recorded. Results Postoperative ROM, VAS, and HSS scores significantly improved compared with preoperative values in both groups (all P < 0.0001). At the final follow-up, the VAS score in the FB group was significantly lower than that in the MB group (P < 0.05), while no significant differences were observed in ROM or HSS scores between the two groups (all P > 0.05). Postoperative FTA, TCVA, and TCPSA values returned to the ideal range in both groups, with no significant intergroup differences (all P > 0.05). The FB group had a significantly shorter operative time (P < 0.05). No severe complications occurred in either group, and the prosthesis survival rate was 100% in both groups. Conclusion Both FB-UKA and MB-UKA significantly improve pain, range of motion, and function in patients with medial compartment knee OA, with comparable efficacy in restoring lower limb alignment. The FB prosthesis offers advantages in pain control and surgical convenience. Clinical selection may be individualized based on patient characteristics and surgeon experience. Keywords Unicompartmental knee arthroplasty; Mobile-bearing prosthesis; Fixed-bearing prosthesis; Osteoarthritis; Complications

【摘要】目的：探讨营养控制状态（CONUT）评分与急性心肌梗死（AMI）患者长期预后的相关性。方法：纳入90例AMI患者，于2021年1月～2023年12月入院，随访2年，分为主要心血管不良事件（MACEs）组（32例）与非MACEs组（58例），回顾性分析并对比两组基线资料，并分析CONUT评分与MACEs的相关性及MACEs的影响因素，评估CONUT评分对MACEs的预测效能。结果：90例AMI患者2年MACEs发生率为35.56%；相较于非MACEs组，MACEs组年龄、糖尿病、血肌酐、C反应蛋白（CRP）、降钙素原（PCT）、N末端脑钠肽前体（NT-proBNP）、KillipⅢ~Ⅳ级、CONUT评分更高，白蛋白、血钙、左心室射血分数（LVEF）更低（P＜0.05）；CONUT评分与MACEs发生正相关（P＜0.05）；高CONUT评分是MACEs的独立危险因素（P＜0.05）；MACEs预测中，CONUT评分的灵敏度为93.75%，特异度为93.10%，曲线下面积（AUC）为0.854。结论：CONUT评分与AMI患者长期预后密切相关，营养不良程度越重，MACEs发生风险越高。

Abstract Objective: To explore the correlation between nutritional control status (CONUT) score and long-term prognosis of patients with acute myocardial infarction (AMI). Methods: 90 AMI patients were included, admitted to the hospital from January 2021 to December 2023, and followed up for 2 years. They were divided into major adverse cardiovascular events (MACEs) group (32 cases) and non-MACEs group (58 cases). The baseline data of the two groups were retrospectively analyzed and compared, and the correlation between CONUT score and MACEs and influencing factors of MACEs were analyzed to evaluate the predictive efficacy of CONUT score for MACEs. Results: The 2-year incidence rate of MACEs in 90 AMI patients was 35.56%; compared with the non-MACEs group, the MACEs group had higher age, diabetes, serum creatinine, C-reactive protein (CRP), procalcitonin (PCT), N-terminal pro-brain natriuretic peptide (NT-proBNP), Killip grades III to IV, and CONUT score. Albumin, blood calcium, and left ventricular ejection fraction (LVEF) were lower (P<0.05); CONUT score was positively correlated with the occurrence of MACEs (P<0.05); high CONUT score was an independent risk factor for MACEs (P<0.05); in the prediction of MACEs, the sensitivity of CONUT score was 93.75 %, the specificity was 93.10 %, and the area under the curve ( AUC ) was 0.854. Conclusion: CONUT score is closely related to the long-term prognosis of AMI patients. The more severe the malnutrition, the higher the risk of MACEs.

目的 探讨血清白蛋白（ALB）、纤维蛋白原（FIB）、乳酸脱氢酶（LDH）水平联合检测对急性心肌梗死患者短期预后的预测价值，以期为临床早期制定相应干预方案、改善患者预后提供参考。 方法 回顾性选取我院2023年1月~2025年1月收治的132例急性心肌梗死患者，入院后均接受经皮冠脉介入术（PCI）术治疗，根据术后6个月是否发生心血管主要不良事件（MACE）分为预后不良组（n=34）、预后良好组（n=98），比较两组临床资料及入院时血清ALB、FIB、LDH水平，Logistic回归方程分析血清ALB、FIB、LDH水平与急性心肌梗死患者PCI术后预后的关系，受试者工作特征（ROC）曲线分析其预测价值。 结果 两组病变血管支数、Killip分级及入院时血清ALB、FIB、LDH水平比较，差异具有统计学意义（P＜0.05）；入院时血清ALB、FIB、LDH水平与PCI术后预后显著相关，均为其独立影响因素（P＜0.05）；绘制ROC曲线结果显示，入院时血清ALB、FIB、LDH对于PCI术后预后不良的预测AUC分别为0.795、0.856、0.832，联合预测预后不良的AUC为0.927（95%CI：0.892~0.963），大于各方案单独预测，敏感度为91.18%，特异度为89.80%；危险度分析显示，血清ALB低水平患者预后不良风险是高水平患者的6.127倍，血清FIB、LDH高水平患者预后不良风险是低水平患者的10.493、8.170倍（P＜0.05）。 结论 血清ALB、FIB、LDH水平联合检测对急性心肌梗死患者PCI术后预后具有较高预测价值，临床可根据其早期评估患者预后不良风险，以制定个体化干预方案，改善患者预后。

摘要：目的 探讨心力衰竭患者住院期间容量管理成效及影响因素。方法 选取2024年1月—2025年12月我院收治的666例心力衰竭患者为调查对象，根据其成效将其分为有效组（n=612）和无效组（n=54）。统计两组患者临床资料及监测指标，采用单/多因素Logistic分析心力衰竭患者住院期间容量管理成效的影响因素。结果 本研究中，心力衰竭患者住院期间容量管理的有效率为91.89%（612/666）。两组年龄、病程、心功能分级及下肢水肿发生率比较（P＜0.05）；性别、体重指数、文化程度、吸烟史、饮酒史、基础疾病比较无明显差异（P＞0.05）。干预前及干预后，两组左室射血时间、左心室做功指数、左心室做功、每搏输出量、心脏指数、心输出量及脑钠肽比较（P＜0.05）。自变量设置为一般资料中对比有差异的指标包括年龄、病程、心功能分级及下肢水肿发生率、左室射血时间、左心室做功指数、左心室做功、每搏输出量、心脏指数、心输出量及脑钠肽，因变量为心力衰竭患者住院期间容量管理成效，进行单因素Logistic回归分析，结果显示，心力衰竭患者住院期间容量管理成效的影响因素是年龄、心功能分级及下肢水肿发生率、左室射血时间、左心室做功指数、左心室做功、每搏输出量、心脏指数、心输出量及脑钠肽。校正年龄、性别等混杂因子，将单因素方差中对比有差异的数据纳入多因素Logistic回归分析，结果显示，心力衰竭患者住院期间容量管理成效的影响因素是年龄、心功能分级及下肢水肿发生率、左室射血时间、左心室做功指数、左心室做功、心输出量及脑钠肽。结论 心力衰竭患者住院期间容量管理成效较好，心力衰竭患者住院期间容量管理成效的影响因素为年龄、心功能分级及下肢水肿发生率、左室射血时间、左心室做功指数、左心室做功、心输出量及脑钠肽。