【摘要】目的:探讨营养控制状态(CONUT)评分与急性心肌梗死(AMI)患者长期预后的相关性。方法:纳入90例AMI患者,于2021年1月~2023年12月入院,随访2年,分为主要心血管不良事件(MACEs)组(32例)与非MACEs组(58例),回顾性分析并对比两组基线资料,并分析CONUT评分与MACEs的相关性及MACEs的影响因素,评估CONUT评分对MACEs的预测效能。结果:90例AMI患者2年MACEs发生率为35.56%;相较于非MACEs组,MACEs组年龄、糖尿病、血肌酐、C反应蛋白(CRP)、降钙素原(PCT)、N末端脑钠肽前体(NT-proBNP)、KillipⅢ~Ⅳ级、CONUT评分更高,白蛋白、血钙、左心室射血分数(LVEF)更低(P<0.05);CONUT评分与MACEs发生正相关(P<0.05);高CONUT评分是MACEs的独立危险因素(P<0.05);MACEs预测中,CONUT评分的灵敏度为93.75%,特异度为93.10%,曲线下面积(AUC)为0.854。结论:CONUT评分与AMI患者长期预后密切相关,营养不良程度越重,MACEs发生风险越高。
Abstract Objective: To explore the correlation between nutritional control status (CONUT) score and long-term prognosis of patients with acute myocardial infarction (AMI). Methods: 90 AMI patients were included, admitted to the hospital from January 2021 to December 2023, and followed up for 2 years. They were divided into major adverse cardiovascular events (MACEs) group (32 cases) and non-MACEs group (58 cases). The baseline data of the two groups were retrospectively analyzed and compared, and the correlation between CONUT score and MACEs and influencing factors of MACEs were analyzed to evaluate the predictive efficacy of CONUT score for MACEs. Results: The 2-year incidence rate of MACEs in 90 AMI patients was 35.56%; compared with the non-MACEs group, the MACEs group had higher age, diabetes, serum creatinine, C-reactive protein (CRP), procalcitonin (PCT), N-terminal pro-brain natriuretic peptide (NT-proBNP), Killip grades III to IV, and CONUT score. Albumin, blood calcium, and left ventricular ejection fraction (LVEF) were lower (P<0.05); CONUT score was positively correlated with the occurrence of MACEs (P<0.05); high CONUT score was an independent risk factor for MACEs (P<0.05); in the prediction of MACEs, the sensitivity of CONUT score was 93.75 %, the specificity was 93.10 %, and the area under the curve ( AUC ) was 0.854. Conclusion: CONUT score is closely related to the long-term prognosis of AMI patients. The more severe the malnutrition, the higher the risk of MACEs.