临床诊疗
目的 分析上颌前部埋伏牙诊断中锥形束CT(CBCT)的应用价值,以期提升疾病诊出率和定位准确率,继而提高治疗有效性。方法 分析2021年1月—2022年7月间于我院口腔门诊进行检查的150例阻生齿患者基本资料,对患者实施口腔锥形束CT检查,进行定位分型。结果 150例患者中阻生牙率100%,其中存在埋伏牙20例,占比13.33%。所有埋伏牙均经CBCT 扫描准确确定了牙体大小、埋伏牙形态、埋伏深度、萌出方向、与相邻齿的位置关系等,为临床医师提供了准确图像参考;共有上颌前部埋伏牙21颗,包括左上颌埋伏牙9颗、右上颌埋伏牙12颗。结论 CBCT检测能够极大提升埋伏牙检测定位的准确性,为医师提供准确影像学参考,以此制定针对性手术方案,在保证治疗效果的同时提升手术安全性,避免一系列并发症的发生,可在埋伏牙阻生齿诊断及治疗中进行推广使用。
论著
目的 了解门诊老年患者补充与替代医学(CAM)使用现状及影响因素。方法 采用便利抽样法,选取2020年11月—2021年2月广东省某三甲医院老年科门诊就诊的老年患者作为研究对象,调查方法采用一般资料调查表和CAM使用情况调查表进行横断面调查。应用二元Logistics回归分析探讨门诊老年患者使用CAM的影响因素。结果 参与调查的123例老年患者中,有75例(61.0%)老年患者使用CAM,使用CAM的项目主要为中草药、药膳等中国传统医学项目。支付方式是门诊老年患者是否使用CAM的影响因素,使用医保支付的患者较公费、自费患者更愿意使用CAM(OR=5.054,95%CI:1.452~17.590,P<0.05)。结论 CAM在门诊应用广泛,我们应充分发挥我国传统医学优势,为老年人疾病防治提供更多的思路。政府层面也可进一步提高医保覆盖范围,让更多的患者有经济能力可以接受安全、有效的治疗。
Objective To investigate the current status of complementary and alternative medicine(CAM)use and the influencing factors of elderly patients in outpatient clinic.Methods Using the convenience sampling method,the elderly patients treated in the geriatric outpatient department of a Class A tertiary Hospital in Guangdong from November 2020 to February 2021 were selected.General data and the CAM usage questionnaire were collected.Binary logistics regression analysis was used to explore the factors influencing CAM use in elderly patients.Results Seventy-five(61.0%)of 123 elderly patients used CAM.Chinese herbal medicine and medicinal diet were the most common CAM.Payment method was a factor affecting whether elderly outpatient patients use CAM.Insured patients were more willing to use CAM than self-funded patients(OR=5.054,95%CI:1.452-17.590,P<0.05).Conclusions CAM is widely used in outpatient clinics.We should make full use of our country’s traditional medicine,to provide different thoughts of diseases prevention and treatment in elderly patients.The government can also further enlarge the coverage of health insurance,so that more patients can afford safe and effective treatment.
论著
目的 探究新斯的明拮抗顺阿曲库铵的时机对患者腹腔镜结直肠癌根治术后肌松残留和早期肺功能的影响。方法 选取于2021年2月—2022年9月在我院行结肠癌根治手术的194例患者为研究对象,以随机数字表法将患者分为空白对照组和试验组,然后结合给予新斯的明治疗时所体现的4个成串刺激(TOF)比值将试验组患者分为试验组A(TOF≤0.1)、试验组B(0.10.8)。对比组间肌松残余情况以及肺功能情况。结果 插管前,试验组A患者TOF比值低于其他组(P<0.01),空白对照组患者TOF比值高于其他组(P<0.01);空白对照组分别与试验组A~E在复苏室接受观察的时间比较,差异无统计学意义(P>0.01);试验组A患者肌松恢复指数低于其他组(P<0.01),空白对照组患者肌松恢复指数高于其他组(P<0.01)。插管前、拔管0.5 h以及拔管24 h时,组间1秒用力呼气容积(FEV1)、用力肺活量(FVC)和FEV1/FVC比较差异无统计学意义(P>0.05)。结论 结直肠癌根治术后给予新斯的明,有助于加快肌松恢复,但不会影响复苏室停留时间与肺功能水平。
Objective To investigate the effect of timing of neostigmine antagonizing cisatracurium on residual muscle relaxation and early lung function in patients underwent laparoscopic radical resection of colorectal cancer.Methods February 2021 to September 2022,194 patients who underwent radical colon cancer surgery in our hospital were selected as the research subjects.The patients were randomly divided into a blank control group and an experimental group using a random number table method.Then,combined with the train-of-four(TOF)ratios observed during neostigmine treatment,the experimental group patients were divided into experimental group A(TOF≤0.1),experimental group B(0.10.8).The residual muscle relaxation and lung function between groups were compared.Results Before intubation,the TOF ratio of patients in experimental group A was lower than that of other groups(P<0.01),while the TOF ratio of patients in the blank control group was higher than that of other groups(P<0.01).There was no significant difference in the observation time between the blank control group and the experimental group A~E in the postanesthesia care unit(P>0.01).The muscle relaxation recovery index of patients in experimental group A was lower than that of other groups(P<0.01),while the muscle relaxation recovery index of patients in the blank control group was higher than that of other groups(P<0.01).There were no significant differences in force expiratory volume in one second(FEV1),forced Vital capacity(FVC)and FEV1/FVC between groups before intubation,0.5 h after extubation and 24 h after extubation(P>0.05).Conclusions Administration of neostigmine after radical surgery for colorectal cancer can accelerate muscle relaxation recovery,but it will not affect the residence time of the postanesthesia care unit and lung function levels.
论著
目的 分析后循环脑梗死(PCCI)患者椎基底动脉狭窄和血清生化指标的相关性。方法 对100例PCCI患者的临床资料进行回顾性分析,依照椎基底动脉狭窄程度将患者分为不稳定斑块组(n=35)、稳定斑块组(n=36)和无斑块组(n=29)。对比3组患者临床一般情况,血清神经细胞因子水平,血清炎症因子水平,并分析PCCI患者椎基底动脉狭窄和血清生化指标的相关性。结果 3组患者再次发病情况与NIHSS评分对比差异有统计学意义,不稳定斑块组高于其他2组(P<0.05),但稳定斑块组与无斑块组比较差异无统计学意义(P>0.05);3组患者脑源性神经营养因子(BDNF)、神经元特异性烯醇化酶(NSE)、中枢神经特异蛋白(S100β)水平对比差异有统计学意义,不稳定斑块组BDNF低于稳定斑块组与无斑块组,不稳定斑块组NSE、S100β高于稳定斑块组与无斑块组(P<0.05),但稳定斑块组与无斑块组对比无差异(P>0.05);3组患者血清C反应蛋白(CRP)、白细胞介素-37(IL-37)、肿瘤坏死因子(TNF-α)、血管细胞黏附分子-1(VCAM-1)、细胞间黏附分子-1(ICAM-1)、人软骨糖蛋白40(YKL-40)水平对比有差异,不稳定斑块组高于其它2组(P<0.05),但稳定斑块组与无斑块组比较差异无统计学意义(P>0.05);Pearson直线相关分析显示,椎基底动脉狭窄与BDNF呈负相关,与NSE、S100β、CRP、IL-37、TNF-α、VCAM-1、ICAM-1、YKL-40呈正相关(P<0.05);多因素 Logistic 回归分析结果显示,BDNF、NSE、ICAM-1、YKL-40是椎基底动脉狭窄的独立危险因素(P<0.05)。结论 PCCI患者椎基底动脉狭窄程度越严重,再次发病率越高,对患者的神经功能影响越严重。同时血清相关神经细胞因子水平和炎症因子水平与椎基底动脉狭窄严重程度具有明显相关性,其中BDNF、NSE、ICAM-1、YKL-40可作为PCCI患者椎基底动脉狭窄预测的重要指标,因此临床上可以通过监测患者的血清相关生化指标为临床诊断及预后判断提供参考依据。
Objective To investigate the correlation between vertebrobasilar artery stenosis and serum biochemical indexes in patients with posterior circulation cerebral infarction(PCCI).Methods One hundred patients with PCCI admitted to our hospital were selected as the study objects,and the clinical data of all patients were retrospectively analyzed.The patients were divided into unstable plaque group(n=35),stable plaque group(n=36)and no plaque group(n=29)according to the degree of vertebrobasilar artery stenosis.The general clinical conditions,serum levels of neurocytokines and inflammatory factors of the patients were compared,the correlation between vertebrobasilar artery stenosis and serum biochemical indicators in patients with PCCI was analyzed.Results The recurrence and NIHSS score of the 3 groups were significantly different,the unstable plaque group was significantly higher than the other 2 groups(P<0.05),but there was no significant difference between the stable plaque group and the no plaque group(P>0.05).The levels of brain-derived neurotrophic factor(BDNF),neuron-specific enolase(NSE)and central nerve specific protein(S100β)in the three groups were significantly different.BDNF in unstable plaque group was lower than that in stable plaque group and no plaque group,while NSE and S100β in unstable plaque group were higher than that in stable plaque group and no plaque group(P<0.05).There was no significant difference between stable plaque group and no plaque group(P>0.05).The levels of serum C-reactive protein(CRP),interleukin-37(IL-37),tumor necrosis factor-α(TNF-α),vascular cell adhesion molecule-1(VCAM-1),intercellular adhesion molecule-1(ICAM-1)and human cartilage glycoprotein 40(YKL-40)in 3 groups were significantly different.The unstable plaque group was higher than the other two groups(P<0.05),but there was no significant difference between the stable plaque group and the no plaque group(P>0.05).Pearson Line correlation analysis showed that vertebrobasilar artery stenosis was negatively correlated with BDNF,and positively correlated with NSE,S100β,CRP,IL-37,TNF-α,VCAM-1,ICAM-1,YKL-40(P<0.05).Multivariate Logistic regression analysis showed that BDNF,NSE,ICAM-1 and YKL-40 were independent risk factors for vertebrobasilar artery stenosis(P<0.05).Conclusions The more severe degree of vertebrobasilar artery stenosis in patients with PCCI,the higher recurrence rate and more serious the impact on the neurological function of patients.At the same time,the levels of serum related neurocytokines and inflammatory factors were significantly related to the severity of vertebrobasilar artery stenosis.BDNF,NSE,ICAM-1 and YKL-40 can be used as important indicators to predict the severity of vertebrobasilar artery stenosis in patients with PCCI.Therefore,monitoring the patient’s serum biochemical indicators of angiography can provide reference for clinical diagnosis and prognosis judgment.
论著
目的 探讨小于4 cm的胃神经鞘瘤(GS)的CT误诊与漏诊原因,从而加深影像科医师对GS的认识,提高其CT检出率及诊断准确率。方法 回顾性分析2019年3月—2022年10月经手术切除及病理证实的10例小于4 cm的GS患者的临床、CT及病理资料。在CT图像上评估肿瘤的位置、大小、形态、密度、强化特点及周围淋巴结等情况。结果 术前CT误诊7例,漏诊2例,仅1例正确诊断;10例病灶均起源于胃黏膜下;9例为圆形或类圆形;7例发生于胃体;平扫密度均低于肌肉组织,均呈渐进性强化。结论 小于4 cm的GS术前误诊率很高,且可发生漏诊。当CT检查提示胃体部黏膜下圆形或类圆形占位病变,平扫呈均匀稍低密度,增强呈渐进性强化时应考虑GS的可能,最终确诊需病理及免疫组化检查。
Objective To investigate the causes of CT misdiagnosis and missed diagnosis of gastric schwannomas(GS)smaller than 4 cm in size,and to improve radiologists’ awareness of GS and increase the detection rate and diagnostic accuracy.Methods Clinical,pathological and CT data of ten surgically and pathologically confirmed GS patients were retrospectively reviewed between March 2019 and October 2022.The location,size,shape,attenuation,enhancement features and surrounding lymph nodes of each tumor on CT were analyzed.Results Of the 10 patients,7 cases were misdiagnosed in preoperative CT examination,two cases were missed diagnosed and only one case was correctly diagnosed.All tumors originated from the submucosa in ten cases,and nine cases showed a round or oval shape.Seven lesions were located in the gastric body,and all tumors had homogeneous low attenuation compared to muscle on plain CT images.All cases displayed mild-moderate to obvious enhancement.Conclusions GS smaller than 4 cm have a high rate of misdiagnosis and missed diagnosis preoperatively.When CT examination indicates a submucosa tumor with a round-like shape in the gastric body and homogeneous mild hypoattenuation on plain CT,the possibility of GS should be raised.Pathological and immunohistochemical examinations are necessary to confirm the final diagnosis.
论著
目的 探讨子宫瘢痕的超声弹性成像结合厚度分析对剖宫产后再妊娠产妇子宫破裂的预测应用。方法 选择2020年1月—2021年12月在中山市中医院分娩的剖宫产术后再次妊娠经阴道分娩(VBAC)产妇作为研究对象。根据纳入和排除标准,共纳入子宫破裂的VBAC产妇32例、非子宫破裂的VBAC产妇90例。通过住院病历信息系统查询研究对象的基本信息及其在妊娠晚期(≥37周)用B超对研究对象行子宫瘢痕厚度和弹性的测量结果,采用受试者工作特征曲线(ROC)曲线分析子宫瘢痕厚度和弹性SI值对子宫破裂的预测作用。结果 子宫破裂组中年龄>35岁、妊娠>2次、与上次剖宫产间隔<2年、新生儿体质量≥3 kg、单层缝合者的比例高于非子宫破裂组(P<0.05)。122例产妇子宫瘢痕厚度的均值为(3.42±0.49)mm,SI的均值为(2.57±0.45)。ROC曲线分析结果显示:子宫瘢痕厚度单独预测子宫破裂的曲线下面积(AUC)为0.805(95%CI:0.730~0.880,P<0.05),cut off值为3.05 mm,灵敏度为0.726,特异度为0.910,约登指数为0.636;子宫瘢痕SI单独预测子宫破裂的AUC为0.730(95%CI:0.635~0.824,P<0.05),cut off值为2.11,灵敏度为0.767,特异度为0.781,约登指数为0.548;子宫瘢痕厚度联合预测子宫破裂的AUC为0.874(95%CI:0.812~0.937,P<0.01),灵敏度为0.875,特异度为0.811,约登指数为0.686。子宫瘢痕厚度结合子宫瘢痕SI值预测子宫破裂的AUC高于单独使用子宫瘢痕厚度(Z=7.611,P=0.041)和子宫瘢痕SI值(Z=25.864,P=0.025)。结论 子宫瘢痕的超声弹性成像SI值联合子宫厚度可有效提高超声对于VBAC产妇子宫破裂的预测效能,具有一定的应用意义。
Objective To study the application of ultrasound elasticity imaging combined thickness analysis of uterine scar in predicting uterine rupture in women pregnant after cesarean section.Methods Pregnant women with vaginal birth after cesarean(VBAC)from January 2020 to December 2021 in Zhongshan Hospital of Traditional Chinese Medicine were selected as the research subjects.A total of 32 VBAC parturients with uterine rupture and 90 VBAC parturients without uterine rupture were included according to the inclusion and exclusion criteria.The basic information of the subjects was queried through the medical record information system of the hospital.In the third trimester(≥37 weeks),the thickness and elasticity of uterine scar were measured by ultrasound,and the predictive effect of uterine scar thickness and elastic SI value on uterine rupture was analyzed by ROC curve.Results Chi-square test showed that the incidence of uterine rupture was higher in patients with age>35 years,pregnancy>2 times,interval from last cesarean section<2 years,newborn weight≥3kg,and the proportion of uterine rupture in single suture was higher than that in double suture(P<0.05).The mean uterine scar thickness of 122 subjects was(3.42±0.49)mm,and the mean SI was(2.57±0.45).The area under curve(AUC)of uterine scar thickness alone for predicting uterine rupture was 0.805(95%CI:0.730-0.880,P<0.05),the cut off value was 3.05 mm,the sensitivity was 0.726,the specificity was 0.910,and the Youden coefficient was 0.636 by ROC curve analysis.The AUC of uterine scar SI alone for predicting uterine rupture was 0.730(95%CI:0.635-0.824,P<0.05),the cut off value was 2.11,the sensitivity was 0.767,the specificity was 0.781,and the Youden coefficient was 0.548 by ROC curve analysis.The AUC of uterine scar thickness combination for predicting uterine rupture was 0.874(95%CI:0.812-0.937,P<0.01),the sensitivity was 0.875,the specificity was 0.811,and the Youden coefficient was 0.686 by ROC curve analysis.The AUC predicted by uterine scar thickness combined with uterine scar SI value was higher than that predicted by uterine scar thickness alone(Z=7.611,P=0.041)and uterine scar SI value(Z=25.864,P=0.025).Conclusions Elastic SI value of ultrasound imaging of uterine scar combined with uterine thickness can effectively improve the prediction efficiency of ultrasound for VBAC maternal uterine rupture,which has certain application significance,but further demonstration is still needed.
论著
目的 丹酚酸B是传统中药丹参的重要生物活性组分,临床应用广泛。新近发现,丹酚酸B具有防治骨质疏松的作用。本研究拟在前期工作基础上,系统地研究丹酚酸B对去卵巢骨质疏松小鼠的作用,探讨其对小鼠间充质干细胞(MSCs)成骨分化的影响。方法 将18只8周龄SPF级别的C57雌性小鼠分为假手术组、骨质疏松组、丹酚酸B治疗组。骨质疏松组和丹酚酸B治疗组行双侧卵巢摘除术。而假手术组则保持正常的卵巢结构,同时去除局部的脂肪。3组均于术后3日内给予抗生素进行抗感染治疗。4周内,丹酚酸B治疗组给予丹酚酸B 2.5 mg/kg腹腔注射,连续12周,2天1次,其余2组在相同的时间内给予等量生理盐水。16周后,在麻醉状态下将所有小鼠处死。应用MicroCT测量了小鼠右后股骨的骨密度。采用qRT-PCR技术,分析小鼠左后股骨骨髓MSCs中Runx2和Osterix的表达。将小鼠右后股骨进行液氮研磨处理,提取蛋白质,用WB法测定OPG和RANKL的含量。结果 骨质疏松组小鼠股骨骨密度比假手术组低(P<0.05),丹酚酸B治疗组小鼠股骨骨密度比骨质疏松组高,但差异无显著性意义(P<0.05)。骨质疏松组小鼠Runx2和Osterix水平低于假手术组(P<0.05),丹酚酸B治疗组小鼠Runx2和Osterix水平比骨质疏松组高(P<0.05)。骨质疏松组小鼠OPG和RANKL蛋白水平低于假手术组(P<0.05),丹酚酸B组小鼠OPG和RANKL蛋白水平比骨质疏松组高(P<0.05)。结论 绝经后骨质疏松症早期对小鼠的骨质疏松具有一定的影响,但还需要更多的实验来验证本研究的结论。
Objective Salvianolic acid B is an important bioactive component of traditional Chinese medicine Salvia miltiorrhiza and is widely used in clinic.Recently,salvianolic acid B has been found to have the effect of preventing osteoporosis.On the basis of previous work,this study intends to systematically explore the effect of salvianolic acid B on ovariectomized mice with osteoporosis,and its effect on the osteogenic differentiation of mouse mesenchymal stem cells(MSCs).Methods Eighteen eight-week-old SPF C57 female mice were divided into sham operation group,osteoporosis group and salvianolic acid B treatment group(6 mice in each group).The osteoporosis group and salvianolic acid B group underwent bilateral ovariectomy.The sham group maintained normal ovarian structure while removing local fat tissue.All three groups were given antibiotics for anti-infection treatment within 3 days after operation.Within 4 weeks,salvianolic acid B treatment group was given salvianolic acid B 2.5 mg/kg intraperitoneal injection for 12 weeks,once every 2 days,and the other 2 groups were given the same amount of saline at the same time.After 16 weeks,all mice were sacrificed under anesthesia.The bone density of the mouse right posterior femur was measured by MicroCT.The expressions of Runx2 and Osterix in the bone marrow of mouse left posterior femur were analyzed by qRT-PCR.The right posterior femur of mice was ground with liquid nitrogen to extract protein,and the contents of OPG and RANKL were determined by WB.Results The bone mineral density of the femur in the osteoporosis group was lower than that in the sham operation group(P<0.05),and the bone mineral density of the femur in the salvianolic acid B treatment group was higher than that in the osteoporosis group,but the difference was not significant(P<0.05).The levels of Runx2 and Osterix in the osteoporosis group were significantly lower than those in the sham operation group(P<0.05),and the levels of Runx2 and Osterix in the salvianolic acid B treatment group were higher than those in the osteoporosis group(P<0.05).The levels of OPG and RANKL protein in the osteoporosis group were significantly lower than those in the sham operation group(P<0.05),while the levels of OPG and RANKL protein in the salvianolic acid B group were higher than those in the osteoporosis group(P<0.05).Conclusions The early stage of postmenopausal osteoporosis has certain effects on osteoporosis in mice,but more experiments are needed to verify the conclusions of this study.
论著
目的 探讨慢性乙型肝炎病毒(HBV)感染对妊娠期糖尿病(GDM)孕妇的妊娠并发症、孕晚期生殖道B族链球菌(GBS)感染情况以及妊娠结局的影响。方法 选取2020年1月1日—12月31日在广州市妇女儿童医疗中心定期产检、足月、单胎妊娠的GDM孕妇共583例,其中合并HBV感染者(GDM+HBV组)48例,无合并者(GDM组)535例。比较2组的妊娠期并发症、妊娠晚期(妊娠35~37周)生殖道GBS感染情况、妊娠结局以及阴道分娩者的母儿结局。结果 与GDM组患者相比,GDM+HBV组患者出现妊娠期肝内胆汁淤积症、孕晚期生殖道GBS感染者比例较高,孕期出现胎盘早剥者比例较高,阴道分娩过程中出现产时发热、羊水粪染和新生儿入住NICU者比例均较高(均P<0.05)。结论 与无合并慢性HBV感染的GDM患者相比,合并慢性HBV感染的GDM患者在围产期的母儿风险升高。
Objective To investigate the effects of chronic hepatitis B virus(HBV)infection on pregnancy complications,group B streptococcus(GBS)infection in third trimester and pregnancy outcome in pregnant women with gestational diabetes mellitus(GDM).Methods A retrospective study of 583 pregnant women with GDM,singleton gestation and cephalic presentation delivered at term in Guangzhou Women and Children’s Medical Center was carried out.Including 48 GDM women complicated with chronic HBV infection(GDM+HBV group)and 535 GDM women without HBV infection(GDM group).Pregnancy complications,GBS infection in third trimester(gestation 35-37 weeks),pregnancy outcomes,maternal and neonatal outcomes of vaginal delivery were compared between the two groups.Results GDM+HBV group had a higher proportion of intrahepatic cholestasis of pregnancy(ICP)and GBS infection in third trimester than GDM group,and a higher proportion of placental abruption during pregnancy.GDM+HBV group showed a significantly increased proportion in intrapartum fever,meconium-stained amniotic fluid and neonatal intensive care unit admission during vaginal delivery than GDM group(all P<0.05).Conclusions GDM women with chronic HBV infection are associated with increased maternal and fetal risk during pregnancy and delivery.
综述
糖尿病已成为全球最严重的健康问题之一。需要白内障手术的糖尿病患者也日益增多,虽然糖尿病的眼表并发症很常见,但由于糖尿病患者全身和眼部疾病十分复杂,使得眼前段如角结膜和泪腺的糖尿病并发症往往被忽视。糖尿病患者白内障超声乳化术有引发或加重眼前节疾病的风险,包括干眼病(DED)、角膜上皮糜烂、上皮缺损迁延不愈,甚至威胁视力的角膜溃疡。这些风险里最为常见的是DED,并且可能因白内障超声乳化手术而加重。眼科医生需要在手术前预先评估已存在的DED是否需要术前治疗,并且需要注意在已存在 DED 的情况下,各项术前检查数据测量的准确性会降低,以及尽可能减少对眼表造成损害的各种手术因素;并考虑通过管理减少术后 DED。本综述就评估白内障超声乳化术对合并糖尿病的老年性白内障患者的眼表术中的影响因素进行分析。
Diabetes mellitus(DM)has become one of the most serious health problems in the world. The number of diabetic patients requiring cataract surgery is also increasing. Although ocular surface complications of DM are common,the complexity of systemic and ocular disease in diabetic patients makes diabetic complications in the anterior segment,such as the cornea and lacrimal gland,often be overlooked. Phacoemulsification in diabetic patients carries the risk of triggering or exacerbating ocular segment disease,including dry eye disease,corneal epithelial erosion,persistent epithelial defects and even vision-threatening corneal ulcers. The most common of these risks is dry eye disease,and it can be exacerbated by cataract phacoemulsification. Ophthalmologists need to preemptively assess the need for preoperative treatment of pre-existing dry eye disease(DED),be aware of the reduced accuracy of preoperative data measurements in the presence of DED,and minimize surgical factors that can damage the ocular surface;and consider management to reduce postoperative DED. In this review,we analyze the factors that influence phacoemulsification in ocular surface surgery for senile cataract patients with diabetes.
论著
目的 探讨磁共振成像(MRI)技术在膝关节隐匿性骨折临床诊断中的应用价值。方法 从我院2020年7月—2022年7月期间接诊的膝关节隐匿性骨折病例中随机抽取78例作为研究对象,所有病例均开展MRI、CT检查,分析并比较MRI和CT检查对该病变的检出率。结果 在78例膝关节隐匿性骨折病例中,MRI检查确诊76例,检出率97.44%,CT检查确诊61例,检出率78.21%,MRI检查对该疾病的检出率相比CT检查更高,差异有统计学意义(P<0.05)。MRI对半月板损伤、关节腔少量积液、韧带损伤、骨折塌陷及水平错位检出率相比CT更高,差异有统计学意义(P<0.05),两种检查方式在严重骨折检出率差异较小,差异无统计学意义(P>0.05)。结论 在膝关节隐匿性骨折的临床诊断中应用MRI对疾病检出率较高,且操作简便,在临床中具有较高的推广价值。
Objective To investigate the application value of magnetic resonance imaging(MRI)in the clinical diagnosis of occult knee fractures. Methods A total of 78 cases of occult knee fracture received by our hospital from July 2020 to July 2022 were randomly selected as research subjects,and MRI and CT examinations were performed on all cases,and the detection rates of MRI and CT examination were analyzed and compared. Results Among the 78 cases of occult knee fracture,76 cases were confirmed by MRI examination,with a detection rate of 97. 44%,and 61 cases by CT examination,with a detection rate of 78. 21%,and the detection rate of MRI examination for this disease was higher than that of CT examination,and the difference was statistically significant(P<0. 05). MRI had higher detection rate of meniscal injury,small effusion in the joint cavity,ligament injury,fracture collapse and horizontal misalignment than CT(P<0. 05),and the difference in the detection rate of severe fractures was small and not statistically significant(P>0. 05). Conclusions The application of MRI in the clinical diagnosis of occult knee fracture has a high disease detection rate and simple operation,and has high promotion value in clinical practice.