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目的 对比剖宫产术后子宫瘢痕妊娠(CSP)与对照组的相关数据,为及早诊断CSP提供帮助;对比不同超声分型CSP超声特征及治疗方式,为早期诊断和个体化治疗方案的制定提供客观依据。方法 回顾性分析我院收治的41例CSP患者及41例对照患者的超声声像图特征及相关临床指标,总结分析不同分型CSP患者所采取的治疗方式。结果 41例CSP患者与41例对照组比较,出现阴道流血的概率更高,差异有统计学意义(P<0.05);根据超声分型将CSP分为4型,分别为Ⅰ、Ⅱ、ⅢA及ⅢB型,Ⅰ型CSP患者与其他3型CSP比较,出现阴道流血的概率要高,差异有统计学意义(P<0.05);Ⅰ型CSP较Ⅱ、Ⅲ、ⅢA型子宫前壁肌层厚,差异有统计学意义(P<0.05);关于治疗:Ⅰ型CSP主要治疗方式为超声引导清宫术;Ⅱ型根据临床实际情况,每一种方式都可选择;Ⅲ型CSP主要采用子宫动脉栓塞后超声引导下清宫术,所有患者术中出血均不多,预后良好并顺利出院。结论 1.CSP患者与对照组临床指标对比有一定差异性,但不够特异,故为了及早的诊断CSP,对于有剖宫产史妇女再次妊娠的早孕检查,一定要明确妊娠囊与子宫前壁下段瘢痕及膀胱的关系;2.超声分型有助于制定针对CSP的个体化治疗方案,以改善患者预后。故诊断CSP的同时,还需对CSP进行准确的超声分型。
Objective To compare the data of cesarean scar pregnancy (CSP) after cesarean section with that of the control group, so as to provide help for the early diagnosis of CSP. To compare the ultrasonic characteristics and treatment methods of different ultrasonic types of CSP, so as to provide an objective basis for early diagnosis and individualized treatment. Methods The ultrasonographic features and related clinical indexes of 41 CSP patients and 41 control patients were analyzed retrospectively, the treatment methods adopted by patients with different types of CSP were summarized and analyzed. Results The probability of vaginal bleeding in 41 patients with CSP was higher than that in 41 control patients, the difference was statistically significant (P<0.05). According to ultrasonic classification, CSP is divided into four types: Ⅰ, Ⅱ, ⅢA and ⅢB. Compared with other 3 types CSPs, patients with type Ⅰ CSP had higher probability of vaginal bleeding, which difference was statistically significant (P<0.05). The main treatment of type Ⅰ CSP was ultrasound-guided uterine curettage, each method could be selected according to the actual clinical situation for type Ⅱ CSP, type Ⅲ CSP mainly adopted ultrasound-guided uterine curettage after uterine artery embolization. All patients had little intraoperative bleeding, good prognosis and been discharged successfully. Conclusions There were some differences in clinical indexes between CSP patients and control patients, but they were not specific enough. Therefore, in order to diagnose CSP as soon as possible, for the early pregnancy examination of second pregnancy in patients with cesarean section, we must clarify the relationship between gestational sac and scar of the lower part of the anterior wall of uterus and bladder. Ultrasound typing is helpful to formulate an individualized treatment plan for CSP patients to improve the prognosis. Therefore, accurate ultrasonic typing is also needed when diagnosing CSP.
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目的 通过分析胎盘植入检出率、胎盘植入典型声像图特征及胎盘植入患者妊娠结局,探讨彩色多普勒超声检查在前置胎盘合并胎盘植入患者诊断中的应用价值。方法 回顾性分析2016年1月—2020年11月在广州市第一人民医院分娩的100例在产前超声检查中诊断为前置胎盘孕妇的临床资料及超声诊断资料。分析彩色多普勒检查在诊断前置胎盘合并胎盘植入中的灵敏度、特异度等指标;比较分析2组孕妇间年龄、流产和剖宫产次数及是否合并凶险性前置胎盘的情况;对比分析2组孕妇间胎盘分布情况、胎盘超声评分情况,分析胎盘植入的标志性超声声像图特征;分析2组孕妇分娩并发症及结局。结果 胎盘植入检出的灵敏度72%(36/50),特异度92.6%(50/54);胎盘植入组流产和剖宫产次数高于非胎盘植入组(P<0.05),合并凶险性前置胎盘的孕妇发生胎盘植入的概率升高;胎盘植入组超声评分高于非胎盘植入组(P<0.05),胎盘内陷窝征和胎盘后间隙消失是胎盘植入的标志性声像图特征;胎盘植入组产时出血量高于非胎盘植入组(P<0.05),胎盘植入组中出现产后出血的概率也是高于非胎盘植入组(P<0.05)。结论 彩色多普勒超声检查在诊断前置胎盘合并胎盘植入中的灵敏度及特异性度均较高,胎盘内陷窝征和胎盘后间隙消失在胎盘植入诊断的检出较高,可作为判断胎盘是否植入的标志性特征。运用超声评分系统可以更加客观地评价胎盘植入的诊断,对于预测其预后有重要的价值,值得推广。
Objective To explore the value of color Doppler ultrasonography in the diagnosis of placenta previa complicated with placenta implantation by analyzing the detection rate of placenta implantation,the typical sonographic characteristics of placenta implantation and the pregnancy outcome of patients.Methods The clinical data and ultrasonic diagnosis data of 100 pregnant women with placenta previa diagnosed by prenatal ultrasound in Guangzhou First People's Hospital from January 2016 to November 2020 were analyzed retrospectively.The sensitivity and specificity of color Doppler in the diagnosis of placenta previa complicated with placenta implantation were analyzed.The age,the number of abortions and cesarean sections and whether there was dangerous placenta previa between the two groups were compared and analyzed.The placental location and placental ultrasound score between the two groups were compared and analyzed,and the characteristics of landmark ultrasound images of placental implantation were analyzed.The delivery complications and outcomes of the two groups were also analyzed.Results The sensitivity and specificity of placenta implantation were 72% (36/50) and 92.6% (50/54).The number of abortion and cesarean section in placenta implantation group was significantly higher than that in non placenta implantation group (P<0.05).The probability of placenta implantation in pregnant women with dangerous placenta previa was significantly higher.The ultrasound score of placenta implantation group was significantly higher than that of non placenta implantation group(P<0.05),intraplacental lacuna sign and disappearance of retroplacental space were the landmark ultrasonographic features of placental implantation.The amount of intrapartum hemorrhage in placenta implantation group was significantly higher than that in non placenta implantation group (P<0.05).The probability of postpartum hemorrhage in placenta implantation group was also significantly higher than that in non placenta implantation group (P<0.05).Conclusions Color Doppler ultrasonography had high sensitivity and specificity in the diagnosis of placenta previa complicated with placenta implantation,intraplacental lacuna sign and disappearance of retroplacental space had high detection rates in the diagnosis of placental implantation,which can be used as a landmark feature to judge whether placenta is implanted or not.The use of ultrasound scoring system can more objectively evaluate the diagnosis of placental implantation,which has important value in predicting its prognosis and is worthy of popularization.
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目的 探讨健康儿童的个体因素对超声测量下腔静脉内径的影响。方法 使用超声测量210例健康儿童的下腔静脉呼气末内径及腹主动脉内径,并记录他们的个体特征,包括性别、年龄、身高、体质量、腰围、体表面积等,进行相关与回归分析。结果 年龄、身高、体质量、腰围、体表面积与下腔静脉和腹主动脉内径呈正相关。年龄是女性儿童下腔静脉内径唯一的独立影响因素,身高是男性儿童下腔静脉内径唯一的独立影响因素。无论男性或女性,年龄是儿童腹主动脉内径的独立影响因素,而下腔静脉和腹主动脉内径的比值不受这些个体因素的影响。结论 下腔静脉和腹主动脉内径易受个体因素影响,而它们的比值不易受个体因素影响,可以更好的用于预测儿童的容量特征。
Objective To explore the impact of individual characteristics on inferior vena cava diameter ( IVC ) in healthy children. Methods IVCmax and abdominal aorta (AO) diameters were measured by ultrasound in 210 healthy children. The individual characteristics including gender, age,height,weight, waist circumference of each child were recorded. Then the surface area(BSA) and IVCmax/AO were calculated to discuss the relationship between them with multivariate analysis. Results Age, height, weight,waist circumference, and BSA were positively correlated with IVCmax and AO. Multivariate linear regression showed that age was the only independent variable for IVCmax in female children, height was the only independent variable for IVCmax in male children, and age was the only independent variable for AO in both females and males. IVCmax/AO was not significantly influenced by the subjects' characteristics. Conclusion IVCmax and AO were more susceptible to subjects' characteristics than IVCmax/AO. IVCmax/AO could be a reliable and practical parameter in children as it was independent of age, height, and weight.
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目的 通过研究微泡超声空化增强微波消融对兔VX2肿瘤的热消融效应来探究其在肿瘤治疗中的价值。方法 24只肝脏移植瘤兔随机分为空白对照组、单纯超声空化治疗组、单纯微波消融治疗组、超声空化联合微波消融治疗组4组。利用增强超声显示每组治疗前后肿瘤的大小、形状和轮廓并通过温度针来检测治疗区域的局部温度。结果 联合治疗组血流灌注缺损最严重,微波消融组和联合治疗组缺损体积分别为1.53±0.20和1.68±0.43(P=0.117);微波消融组以及联合治疗组消融治疗时温度达平台时间分别为(21.7±5.0)s和(10.3±5.0)s(P<0.01),最高温度(℃)分别为100.9±5.0和134.1±6.0(P<0.01)。结论 MWA联合MEUS治疗肝癌可使治疗区局部温度急剧升高至峰值温度,有望提高肝癌治疗效果。
Objective To investigate the thermal ablation effect of microbubble ultrasound cavitation combined with microwave ablation on rabbit VX2 tumors. Methods Twenty-four rabbits with liver transplantation tumors were randomly divided into four groups: blank control group, ultrasound-only cavitation treatment group, microwave-only ablation treatment group, and ultrasound-cavitation combined with microwave ablation treatment group. Enhanced ultrasound was used to show the size, shape and contour of the tumor before and after treatment in each group, and the local temperature of the treatment area was detected by a temperature needle. Results The blood flow perfusion defect was the most severe in the combined treatment group. The defect volume of the microwave ablation group and the combined treatment group were 1.53±0.20 and 1.68±0.43 (P=0.117). The temperature reached the plateau time in the microwave ablation group and the combined treatment group. It was (21.7±5.0)s and (10.3±5.0)s (P<0.01), and the highest temperature (℃) was 100.9±5.0 and 134.1±6.0 (P<0.01). Conclusion MWA combined with MEUS for liver cancer can sharply increase the local temperature in the treatment area to the peak temperature, which is expected to improve the treatment effect of liver cancer.
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目的 探讨低机械指数诊断超声及低声压治疗超声对造影剂微泡的作用效果。方法 低机械指数的诊断超声及不同声压下低能量治疗超声体外辐照造影剂微泡,通过获得的超声造影图像间接分析微泡总浓度的变化,探讨不同机械指数诊断超声及不同声压治疗超声下微泡发生稳定空化及惯性空化情况。结果 低机械指数(<0.2)诊断超声及低声压(<0.15 MPa)治疗超声下微泡以稳定空化为主,随着机械指数增高或声压增高,微泡以稳定空化和惯性空化两种方式并存,当机械指数>0.3或声压>0.2 Mpa时,微泡以惯性空化为主。结论 微泡在低机械指数及低声压作用下发生不同空化效应,随着机械指数或声压增加,微泡破坏增加,以惯性空化效应为主。
Objective To investigate the effect of low mechanical index diagnostic ultrasound and low acoustic pressure therapy on contrast agent microbubbles. Methods Microbubbles were irradiated by diagnostic ultrasound with low mechanical index(MI) and low energy therapy under different acoustic pressure. To obtain the images, and analyze the change of microbubble concentration,the movement trend of microbubbles under different MI and different acoustic pressure were analyzed, to estimated stable cavitation or inertial cavitation of microbubbles. Results Stable cavitation was the main form of microbubbles under low mechanical index (< 0.2) diagnostic ultrasound and low acoustic pressure (< 0.15Mpa). With the increase of mechanical index or acoustic pressure, stable cavitation and inertial cavitation coexisted. When mechanical index > 0.3 or sound pressure > 0.2MPa, microbubbles were mainly inertial cavitation. Conclusion The cavitation effects of microbubbles under low mechanical index and low acoustic pressure are different. With the increase of mechanical index or acoustic pressure, the damage of microbubbles increases, and main effect is the inertial cavitation.
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目的 分析经胸超声心动图在Stanford A 型主动脉夹层的直接征象、间接征象和优缺点,探讨超声心动图在其诊断及预后评估中的应用价值。方法 回顾性收集2018年9月—2020年6月在我院诊治的A型主动脉夹层患者的临床资料,分析超声心动图的应用价值,以及住院期间发生不良预后的高风险因素。结果 经胸超声心动图直接征象诊断 A 型主动脉夹层的敏感性低于CTA,但对受累主动脉瓣结构及其功能评价优于CTA。 院内不良预后的发生率为42%, A型夹层的病因多与高血压相关,主动脉瓣返流、心包积液、手术时间长等是其高风险因素。结论 经胸超声心动图对A型主动脉夹层的早期诊断有较高的初筛价值,在局限于主动脉窦部夹层及观察主动脉瓣是否受累及有独特的优势,对于手术方式的选择和预后的判断有指导意义。
Objective To analyze the direct signs, indirect signs, advantages and disadvantages of transthoracic echocardiography in Stanford A-type aortic dissection, and explore the application value of echocardiography in its diagnosis and prognostic evaluation. Methods Retrospectively collect the clinical data of patients with type A aortic dissection diagnosed and treated in our hospital from Sept 2018 to Jun 2020, and analyze the application value of echocardiography and the high-risk factors for poor prognosis during hospitalization. Results The direct signs of transthoracic echocardiography were less sensitive than CTA in the diagnosis of type A aortic dissection, but it was better than CTA in evaluating the structure and function of the affected aortic valve. The incidence of poor prognosis in the hospital was 42%. The cause of type A dissection was mostly related to hypertension. Aortic regurgitation, pericardial effusion, and long operation time were high-risk factors. Conclusion Transthoracic echocardiography has a higher initial screening value for the early diagnosis of type A aortic dissection. It has unique advantages in confining to the aortic sinus dissection and observing whether the aortic valve is involved, the choice of surgical methods and the judgment of prognosis has guiding significance.
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目的 了解颈内动脉超声联合经颅多普勒对产后抑郁症患者的检测效果,为临床产后抑制治疗提供有价值的线索。方法 收集本院于2018年3月—2020年2月收治的78例符合抑郁障碍诊断标准的产妇资料,对资料予以回顾研究,并设为研究组,同时另择选78例健康产妇为对照组,应用颈内动脉超声对两组产妇的颈动脉血流参数[颈动脉内径(D)、收缩期峰值流速(PSV)、舒张末期流速(EDV)以及阻力指数(RI)]进行检测,同时联合经颅多普勒超声(TCD)对两组产妇的左右大脑中(MCA)、脑前(ACA)及脑后(PCA)的动脉与椎基底动脉(VA-BA)血流速度进行监测,并分析两组产妇阻力指数(RI)与搏动指数(PI)变化,对以上数据统计分析并给予组间比较分析。结果 与对照组比较,研究组D、EDV水平明显下降,而RI值升高,差异有统计学意义(P<0.05);两组产妇的PSV比较,差异无统计学意义(P>0.05);研究组抑郁产妇的左右大脑中(MCA)、脑前(ACA)及脑后(PCA)的动脉血流速度均加快且差异均有统计学意义(P均<0.05);研究组抑郁产妇的椎基底动脉(VA-BA)血流速度与对照组比较减慢,差异有统计学意义(P<0.05);研究组抑郁产妇的阻力指数(RI)与搏动指数(PI)值与对照组比较,差异均无统计学意义(P>0.05);78例抑郁产妇中,62例呈现脑动脉血流异常。检测异常率为79.49%(62/78)。结论 经颅多普勒检测,可见产后抑郁产妇的3条脑动脉血流速度明显加快,而椎基底动脉血流减缓,由此提示抑郁产妇脑动脉痉挛且脑供血明显不足,颈内动脉超声显示抑郁产妇的颈动脉血流参数有一定变化,能够为产后抑郁患者的治疗提供一定参考。
Objective To understand the detection effect of internal carotid artery ultrasound combined with transcranial Doppler on patients with postpartum depression, and to provide valuable clues for clinical postpartum depression treatment. Methods The data of 78 parturients who met the diagnostic criteria for depression in our hospital from March 2018 to February 2020 were collected. The data were reviewed and set as the study group. At the same time, 78 healthy parturients were selected as the control group.We used internal carotid artery ultrasound to detect the carotid blood flow parameters [carotid artery diameter (D), peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance index (RI)] of the two groups of parturients, and combined transcranial color Doppler ultrasound (TCD) to monitor the blood flow velocity of the arteries and vertebrobasilar artery (VA-BA), middle cerebral artery (MCA), anterior cerebral artery (ACA) and posterior cerebral artery (PCA) of the two groups of women. The changes in maternal RI and PI between the two groups were analyzed, and the above data were statistically analyzed and compared between groups. Results Compared with the control group, the D and EDV levels of the study group were decreased, while the RI value was increased, the difference was statistically significant (P<0.05). The comparison of PSV between the two groups was not statistically significant (P>0.05). The arterial blood flow velocity in MCA, ACA, and PCA of the depressed women in the study group were accelerated and the differences were statistically significant (P<0.05). The blood flow velocity of VA-BA of the depressed women in the study group was slower than that of the control group, and the difference was statistically significant (P<0.05). RI and PI values of depressed women in the study group were compared with those of the control group. There was no statistically significant difference between the groups (P>0.05). Among 78 depressed women, 62 had abnormal cerebral artery blood flow. The abnormal detection rate was 79.49% (62/78). Conclusion Transcranial Doppler examination showed that the blood flow of the three cerebral arteries of the postpartum depressed women was increased, while the blood flow of the vertebrobasilar arteries slowed down, which indicated that the depressed women had cerebral artery spasm and the cerebral blood supply was obviously insufficient. The internal carotid artery ultrasound showed there were certain changes in carotid blood flow parameters of depressed mothers, which can provide a certain reference for the treatment of patients with postpartum depression.
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目的 探讨超声引导下宫颈癌根治术的应用效果及对患者远期生存率的影响。方法 选取本院2015年1月—2017年12月共收治的70例宫颈癌患者作为研究对象,将2016年7月—2017年12月纳入的患者作为观察组,2015年1月—2016年6月纳入的患者作为对照组,各35例,给予对照组患者常规腹腔镜根治术,给予观察组患者超声引导定位下腹腔镜宫颈癌根治术联合高强度凝聚超声热凝技术治疗。对比两组患者的治疗效果、远期生存率与复发率以及术后6个月、1年、2年、3年的FACT-G评分情况。结果 两组疾病控制率对比无差异(97.14% vs 85.71%,P>0.05);观察组的治疗总有效率为高于对照组的(85.71% vs 60.00%,P<0.05);观察组和对照组患者1年生存率对比无差异(P>0.05),观察组2年、3年生存率高于对照组(P<0.05),观察组和对照组1年局部复发率对比无差异(P>0.05),观察组的2年、3年局部复发率低于对照组(P<0.05);观察组术后6个月、1年、2年、3年的FACT-G评分高于对照组(P<0.05)。结论 应用超声引导定位下腹腔镜宫颈癌根治术联合高强度凝聚超声热凝技术治疗宫颈癌能够提升患者的治疗效果,减少疾病复发和提高远期生存率,提升患者的生存质量,值得临床应用推广。
Objective To investigate the application effect of ultrasound-guided radical hysterectomy for cervical cancer and its influence on the long-term survival rate of patients. Methods A total of 70 patients with cervical cancer admitted from January 2015 to December 2017 were selected as the research subjects, and the patients enrolled from July 2016 to December 2017 were selected as the observation group, patients from January 2015 to June 2016 as the control group, each with 35 cases. The control group was given conventional laparoscopic radical hysterectomy, and the observation group was given ultrasound-guided laparoscopic radical hysterectomy combined with high-intensity ultrasound coagulation technology. The treatment effect, long-term survival rate, recurrence rate and FACT-G scores 6 months, 1 year, 2 years and 3 years after operation were compared between the two groups. Results There were no significant differences in disease control rates between the two groups (97.14% vs 85.71%, P>0.05); the total effective rate of treatment in the observation group was higher than that in the control group (85.71% vs 60.00%, P<0.05). There was no significant difference in the 1-year survival rate between the observation and the control group (P>0.05). The 2-year and 3-year survival rate of the observation group were higher than that of the control group (P<0.05). There was no significant difference in comparison of 1-year local recurrence rate between the observation group and the control group (P>0.05). The 2-year and 3-year local recurrence rate of the observation group were lower than that of the control group (P<0.05). FACT-G scores in the observation group after surgery at 6 months, 1 year, 2 years, and 3 years were significantly higher than the control group (P<0.05). Conclusion The application of ultrasound-guided laparoscopic radical hysterectomy combined with high-intensity ultrasound coagulation in the treatment of cervical cancer can improve the treatment effect, reduce disease recurrence rate, increase long-term survival rate, and improve the quality of life of patients, which is worthy of clinical application and promotion.
论著
目的 探究超声-微泡介导的miR-128通过调节PTEN对乳腺癌细胞阿霉素耐药的影响。方法 qPCR检测miR-128在乳腺癌细胞系中的表达,并利用结合微泡的miR-128质粒(质粒+超声+SF6微泡)转染细胞,探究超声-微泡介导的miR-128对乳腺癌细胞阿霉素耐药的影响。CCK8实验检测乳腺癌细胞的活性;qPCR检测过表达miR-128后对PTEN的影响和对乳腺癌细胞阿霉素耐药的影响。结果 miR-128在阿霉素耐药乳腺癌细胞中低表达;过表达miR-128能够增加乳腺癌细胞对阿霉素的敏感性,超声-微泡介导的miR-128进一步增强了乳腺癌细胞对阿霉素的敏感性;miR-128通过调节PTEN从而促进乳腺癌细胞对阿霉素耐药。结论 miR-128过表达可以增强乳腺癌对阿霉素的敏感性,超声-微泡介导的miR-128进一步增强了乳腺癌细胞对阿霉素的敏感性,本研究为乳腺癌阿霉素耐药的治疗提供了新的分子靶标和治疗途径。
Objective To explore the effect of ultrasound-microbubble mediated miR-128 on doxorubicin resistance in breast cancer cells by regulating PTEN. Methods Quantitatine PCR (qPCR) was used to detect the expression of miR-128 in breast cancer cell lines, and the ultrasound-microbubble combined miR-128 plasmid(plasmid+ultrasound+SF6 microbubbles) was used to transfect the cells to explore the effects of ultrasound-microbubble mediated miR-128 on doxorubicin resistance in cancer cells. The CCK8 experiment was used to detect the activity of breast cancer cells; qPCR was used to detect the effect of overexpression of miR-128 on PTEN and the effect on doxorubicin resistance of breast cancer cells. Results miR-128 was under-expressed in doxorubicin-resistant breast cancer cells; overexpression of miR-128 increased the sensitivity of breast cancer cells to doxorubicin,ultrasound-microbubble mediated miR-128 further enhanced breast cancer cells sensitivity to doxorubicin; miR-128 promote resistance to doxorubicin in breast cancer cells by regulating PTEN. Conclusion Overexpression of miR-128 could enhance the sensitivity of breast cancer to doxorubicin. Ultrasound-microbubble mediated miR-128 further enhanced the sensitivity. This study provided a treatment for doxorubicin resistance in breast cancer with new molecular targets and therapeutic approaches.
临床诊疗
目的 探讨三维超声技术对胃癌检出及TNM分期的诊断价值。方法 取2015年2月—2017年9月河南省南阳市中心医院收治的89例胃癌患者作为研究对象,并对其进行术前二维超声(2D-US)、三维超声(3D-US)检查,观察患者体内肿瘤病灶形态、长径及病变浸润程度,同时根据2010年国际抗癌联盟(UICC)制定的TNM分期标准预测胃癌分期,并将预测分期结果与术后病理分期结果进行比较。结果 89例胃癌患者中,胃体癌22例,胃窦癌28例,贲门胃底癌17例,全胃癌22例;其中,黏液腺癌16例,低分化腺癌26例,中高分化腺癌35例,未分化癌12例;TNM分期:T1期18例,T2期25例,T3期31例,T4期15例。3D-US胃癌检出准确率(95.51%)高于2D-US(80.90%),差异有统计学意义(P<0.05);3D-US检出胃癌T1期准确率(94.12%)高于2D-US(53.33%)(P<0.05);3D-US检出胃癌T2期准确率(95.83%)高于2D-US(70.00%)(P<0.05);3D-US检出胃癌T3期准确率(100.00%)高于2D-US(81.48%)(P<0.05);3D-US检出胃癌T4期准确率(100.00%)高于2D-US(60.00%)(P<0.05)。结论 3D-US图像清晰、直观、立体感强,可充分显示2D-US不能显示的肿瘤立体结构,从而提高胃癌检出准确率和术前TNM分期预测准确率,临床推广应用价值较高。