临床诊疗
目的 研究鼓室成形术后慢性中耳炎患者的耳鸣变化情况,并探讨患者术后耳鸣变化情况与术后听力提高的相关关系。方法 记录并分析于我科住院治疗的160例慢性中耳炎患者在术前及鼓室成形术术后6个月的听力变化以及耳鸣症状的改变。结果 有60例患者术前伴有耳鸣,术后23例患者耳鸣治愈;27例治疗有效; 10例治疗无效,则术后耳鸣治疗有效率为83.33%。术后可提高两组患者的气导听力,且耳鸣改善明显组较耳鸣改善不良组提高较为显著(t=0.047,0.005,均P<0.05)。结论 慢性中耳炎患者采用鼓室成形术对耳鸣的治疗有积极影响,术后可提高慢性中耳炎患者的气导听力,进而使耳鸣症状缓解,其中低频气导听力更能缓解耳鸣症状。
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目的 了解广州市海珠区在校学生结核病核心知识知晓率现状、对结核病态度及相关行为,为进一步加强学校结核病健康教育工作提供依据。方法 采用分层整群随机抽样的方法随机选取海珠区内6所学校268名学生进行问卷调查,采用描述性分析、卡方检验。结果 学生结核病知识总知晓率为76.4%,女生结核病知识知晓率比男生高,高中生比大学生和初中生高,市内学生比市外学生知晓率高;户籍是市内的学生更愿意去了解结核病,女生比男生高,市内比市外的学生更加愿意成为志愿者;对于出现结核病疑似症状,大学生更为主动地寻求医生帮助,女学生在自己得了肺结核后会更加主动提醒周围人去检查。结论 学生对结核病的总知晓率仍偏低,以后的结核病健康教育应进一步针对学生的不同特征采取更合适的方式进行宣传,提高学生对结核病的知晓率,促使其形成正确的态度和行为。
Objective To understand the status of the awareness rate of tuberculosis knowledge,attitude and behavior among students in Haizhu district, Guangzhou, and to provide evidence for further strengthening the work of tuberculosis health education in schools. Methods Applying stratified random sampling method to choose 268 students from 6 schools for questionnaire investigation and used descriptive statistical analysis method, Chi-square test to assess related indicators. Results The awareness rate of TB knowledge was 76.4%, female students' was higher than male students', high school students' was the highest, Guangzhou household registers was higher than that no householder in Guangzhou; the students of householder in Guangzhou were more willing to learn about TB, female students' and the students of householder in Guangzhou were more willing to become a volunteer; College students were more active to seek medical help, female students after they had pulmonary tuberculosis would more active to remind the people around to have a check. Conclusion The level of knowledge about tuberculosis among students in the district was still lower than the standard. The health education of tuberculosis knowledge should further make publicity according to the different features of the students, to improve the students the awareness of TB and to promote the formation of correct confidence and behavior
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目的 调查药学本科大学三年级学生在毕业实习前对实习的整体观念及心态。方法 采用问卷表方式调查,将回收问卷表进行数据统计并分析结果。结果 占总比63.2%学生对未来实习方向较模糊,并期望获得相关指导;72.8%学生认为药学专业知识对实习有帮助;90.0%学生认为实习是为即将就业打基础;对于寻找实习单位的方式,三分之一以上学生比较倾向于药学专业老师介绍推荐,大约三分之一的学生有意自己联系实习单位。结论 该调查结果较为真实反映某高校药学本科生实习前的心态及其对实习整体观念,为高校实习管理及学生工作部门了解学生的实习想法提供可靠数据依据,也为教务部门制定“以人为本”实习计划提供了科学依据。
Objective To investigate the overall concept and state of mind of the undergraduates in the grade three undergraduate students before internship. Methods The questionnaire was used to investigate the form of the questionnaire, and the data were collected and analyzed. Results 63.2% of the students for the future practice direction was fuzzy, and hope to get the guidance;72.8% of the students thought pharmacy specialized knowledge is helpful to practice; 90.0% students thought practice was foundation for employment; To find the internship units, more than one third of the students tend to get recommend by pharmacy professional teachers. About one third of students wished to contact their internships by themselves. Conclusion The survey results showed mentality and the overall concept in practice of pharmacy students in our school. It can provided reliable data basis for the practice of management to understand the students practice idea, and also for the educational administration department to develop the “people-oriented” internship program.
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目的 探讨重症急性胰腺炎诊治特点。方法 回顾性分析13例重症急性胰腺炎患者临床资料,包括一般资料、生化检测及影像资料、治疗措施与预后结果,纳入标准为急性胰腺炎合并器官衰竭>48 h(改良Marshall评分≥2分)。结果 重症急性胰腺炎患者一般资料中普遍突出存在心率增快(121.07±28.09)次/分、APACHE II评分偏高(18.92±7.34),病因排序则是高脂血症(38.5%)>胆石症(30.8%)>酒精性(23.1%),SAP合并ARDS发生率可达46.2%,合并AKI则高达69.2%;WBC(12.60±5.57)×109/L、CRP(138.16±67.06)mg/L及PCT(15.76±27.33)ng/L等炎症指标升高提示SAP普遍存在炎症反应,影像学中69.2%患者合并发生肺炎及腹腔积液则提示多处感染部位,其他脏器指标异常升高也提示SAP患者心肺肝肾均存在不同程度的受损;接受CRRT治疗及呼吸支持可分别达46.2%及76.9%,7天内死亡例数为1例(7.7%),28天内死亡例数为4例(30.8%),ICU及总住院时间为(10.77±7.38)及(19.61±13.40)天。结论 重症急性胰腺炎是全身及局部性的炎症反应累及全身各个脏器的急性复杂病变,以合并发生ARDS及AKI为临床特征,需要多器官功能保护与替代、外科干预等多学科综合协作治疗。
Objective To evaluate characteristics of diagnosis and treatment on severe acute pancreatitis. Methods To respective analysis clinical data of 13 patients with severe acute pancreatitis. The data included baseline characteristics, biochemical tests and imaging data, treatment and prognosis, inclusion criteria for acute pancreatitis with organ failure > 48 h (modified Marshall score > 2). Results Higher heart rate(121.07±28.09) times/min and APACHEII scores(18.92±7.34) were universally found in SAP, which primary disease contained hyperlipidemia (38.5%) > cholelith disease (30.8%) > alcohol (23.1%) with incidence of ARDS and AKI being 46.2% and 69.2%; Higher inflammatory biomarkers including WBC(12.60±5.57)×109/L, CRP(138.16±67.06)mg/L and PCT(15.76±27.33)ng/L indicated widespread inflammation with many infection sites revealing by 69.2% pneumonia and peritoneal effusion on imaging; Other abnormally biochemical index prompted some injury of viscera including heart, lungs, kidney and liver; 1 case suffered death within 7 days and 4 cases also did within 28 days, ICU and total length of hospital stay was (10.77±7.38) and (19.61±13.40) days, CRRT treatment and respiratory support respectively reached 46.2% and 46.2%. Conclusion Severe acute pancreatitis is a acute complex pathological changes on various organs induced by acute systemic and local inflammation with feature of mergence with the ARDS and AKI, which need the multidisciplinary integrated collaborative treatment on organ function protection and sustain and surgical intervention.
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目的 对急诊留观病历中存在的质量问题予以分析,探索提高其书写质量的有效措施,优化管理流程。方法 根据卫生部《病历书写基本规范》、《医疗机构病历管理规定》和《广东省病历书写与管理规范》对2015年6月—12月某院1200份急诊留观病历进行质量检查,对其问题进行汇总分析。结果 发现存在质量缺陷的病历998份,缺陷数4478项,以缺权利义务告知书、授权委托书或填写漏项、出观记录入观情况简单复制、缺验单、病程记录过于简单等缺陷位居前四位,占78.67%。结论 急诊留观病历缺陷突出。临床医师及医院管理者需要就此进行针对性整改,以提高和控制急诊留观病历质量。
Objective To analyze deficiencies of medical records from emergency observation room and explore effective procedures to enhance writing quality of medical records and its management. Methods One thousand two hundred medical records from emergency observation room during June to December 2015 were analyzed according principles of medical records writing,regulations for medical records management in medical institutions by Ministry of Health and regulation for medical records writing and management in Guangdong province. Results 998/1200 medical records were found with deficiency and the total deficiencies were 4478 items. The prominent four types of deficiencies, occupying 78.67%, included absence or incompleteness of the notification of the rights and obligations and power of attorney, simple copy and paste of the medical records, absence of medical test results and too simplicity of the recording of the disease process. Conclusion Prominent deficiencies were found in medical records from emergency observation room. The clinical physicians and hospital administrators should take effective procedures to improve and control the quality of the medical records.
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目的 探讨信息预警系统在住院患者压疮风险管理中的运用。方法 应用描述性分析,χ2检验和t检验方法,对实施信息预警系统前后的院内压疮发生率、压疮护理质量管理指标以及使用纸质版和电子版Waterlow量表评估患者压疮危险的平均时间进行比较。结果 试行信息预警系统后,院内压疮发生率下降至0.11‰;护士对压疮危险患者评估率、动态评估率和预防压疮措施落实率都明显升高;护士使用电子版Waterlow量表评估患者压疮危险耗时显著减少。结论 信息预警系统在住院患者压疮风险管理中起到重要作用,为临床护理和护理管理提供了良好的工具,保障患者安全。
Objective To explore the application of risk management information system in the inpatients' risk management of pressure ulcers (PUrs). Methods A descriptive analysis, Chi-square test and T-test were used to analyze the incidence of inpatients' PUrs and indicators of the nursing quality control before and after applying the risk management information system. Results After using this information system, incidence of PUrs decreased to 0.11‰ . Rate of registered nurses' assessment on inpatients' with PUrs risk and dynamically assessment rose obviously. The rate of prevention of PUrs went up as well. The mean time to assess inpatients' PUrs risk with electronic Waterlow scale was significantly less than the mean time of paper Waterlow scale. Conclusion The risk management information system played a vital role in the inpatients' PUrs risk management. It could provide an effective tool for the clinical nursing's quality control, improve registered nurses' efficiency and protect inpatients'safety.
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目的 观察康复路径在髋关节置换术后的临床应用效果,探讨其临床应用价值 。方法 将广州市第一人民医院2014年10月—2015年10月收治行髋关节置换术患者100例为研究对象,随机分为对照组与观察组各50例。对照组采取常规围手术期护理,观察组按照康复路径护理,比较两组患者术后并发症、住院时间、费用、患肢功能以及日常生活自理能力。结果 观察组住院时间和住院费用均少于对照组(P<0.01);两组术后并发症发生率、患肢功能评分及日常生活自理能力比较,差异均有统计学意义(P<0.01 )。结论 康复计划护理用于髋关节置换术后效果显著,可明显降低患者术后并发症,缩短住院时间,降低住院费用,有利于促进患者术后功能以及自理能力的恢复。
Objective To observe the effect of clinical application of rehabilitation in the path of a hip replacement, and to explore its clinical application value. Methods October 2014 to October 2015 in Guangzhou First People's Hospitalhip arthroplasty cases werecollected of 100 patients as the research object, randomly divided into control group and observation group with 50 cases in each group. The control group adopted conventional perioperation period nursing care, observation group in accordance with the recovery paths. We compared two groups of patients complications, hospitalization time, expense, limb function and activities of daily living. Results In the observation group, the hospitalization time and cost of hospitalization were significantly less than that of the control group (P<0.01); The incidence of limb function score, ability of daily living and postoperative complications were compared between the two groups, the differences were statistically significant (P<0.01). Conclusion Rehabilitation nursing care plans for after hip replacement effect is significant. It can significantly reduce the postoperative complications, shorten the time of hospitalization, reduce hospitalization expenses, and is beneficial to the recovery of the function of promoting postoperative and self-care ability.
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目的 追踪随访186例甲状腺微小乳头状癌(Papillary Thyroid Microcarcinoma,PMC)患者术后5年及10年的肿瘤复发率、生存率、及术后并发症,探讨不同手术方式对治疗甲状腺微小乳头状癌预后。方法 临床资料为1993—2003年收治的186例甲状腺微小乳头状癌患者,102例行患侧甲状腺大部分切除术(Ⅰ组),84例行患侧甲状腺全切术+峡部切除+对侧甲状腺大部分切除+中央区淋巴结清扫术(Ⅱ组)。结果 Ⅰ组患者术后5年及10年期间肿瘤复发率、生存率与Ⅱ组差别无统计学意义(P﹥0.05),对比I组,Ⅱ组患者术后发生甲状腺及甲状旁腺功能低下的发生率较高,且差别有统计学意义(P﹤0.05)。结论 甲状腺微小乳头状癌预后良好,实行患侧甲状腺大部分切除术对治疗甲状腺微小乳头状癌是安全可行的。
Objective To follow-up 186 cases of papillary thyroid microcarcinoma and analyse their tumor recurrence rate、survival rate and complicationg after 5 and 10 years postoperation, to investigate prognosis of papillary thyroid microcarcinoma from different operation approaches. Methods 186 cases of papillary thyroid microcarcinoma were from 1993 to 2003. All the patients were divided into two groups,102 cases(group Ⅰ) performed with resection of the majority of thyroid gland, and 84 caces(group Ⅱ) performed with total thyroidectomy, thyroidectomy+isthmus thyroidectomy+contralateral thyroid lobectomy+central lymph node ablation. Results The recurrence and survival rates after 5 and 10 years were not significantly different between the two groups, but compared group Ⅰ, the incidences of hypocalcemia and hypothyroidism were higher in group Ⅱ(P<0.05). Conclusion Papillary thyroid microcarcinoma had better prognosis. Resection of the majority of thyroid gland treating papillary thyroid microcarcinoma is safe and feasible.
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目的 观察体重管理对轻型代谢综合征患者的体重指数、血糖、血压、甘油三酯等指标的影响。方法 将40例新诊断的轻型代谢综合征患者随机分成体重管理组和对照组,每组20例。两组患者分别于干预前、干预3月、干预6月检测体重指数、血糖、血压、甘油三脂等治疗,并比较两组患者上述指标。结果 干预6月后,体重管理组的体重指数、甘油三酯均显著性低于对照组,差异有统计学意义(P均<0.05);体重管理组的高密度脂蛋白高于对照组,但无统计学差异。干预6月,体重管理组中血压、血糖达标率高于对照组,差异有统计学意义。结论 体重管理能改善轻型代谢综合征患者的体重指数、血糖、血压、甘油三脂等指标。
Objective To investigate the influence of weight management to body index, blood glucose, blood pressure and triglycerides in mild metabolic syndrome. Methods 40 mild metabolic syndrome patients were randomly divided into weight management group (20 patients) and control group (20 patients). The body index, blood glucose, blood pressure and triglycerides were observed and compared before intervention, 3 months and 6 months after intervention. Results After 6 months intervention, the body index and triglycerides in weight management group were significantly lower than the control group (P<0.05). High density lipoprotein cholesterol in the weight management was higher than the control group, but there was no significant. The success rate of blood glucose and blood pressure were significantly higher than the control group. Conclusion Weight management can significantly improve the body index, blood glucose, blood pressure and triglycerides in patients with mild metabolic syndrome.
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目的 探讨注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的影响。方法 选取2012年11月—2015年10月于我院接受治疗的宫颈癌患者110例,随机分为对照组和观察组,每组各55例,两组患者均接受紫杉醇联合顺铂同步放疗,而观察组患者在此基础上接受每日静脉滴注注射用黄芪多糖治疗,连续应用10天。对比分析两组患者的临床疗效以及治疗前后的血象。结果 经过治疗后,观察组的治疗总有效率为61.81%,明显高于对照组的38.18%,差异有统计学意义(P<0.05);两组患者经过放化疗后其白细胞、红细胞和血小板计数均有不同程度的降低,而与对照组相比,观察组患者下降不明显。结论 注射用黄芪多糖可以减轻宫颈癌放化疗所致的骨髓抑制,对骨髓具有一定的保护作用,在临床治疗宫颈癌的过程中值得推广应用。
Objective To explore the clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy. Methods 110 cases of patients with cervical carcinoma treated in our hospital from November 2012 to October 2015 in our hospital were selected and divided into control group and observation group, each group contains 55 cases. Both groups of patients received radiotherapy and chemotherapy of paclitaxel combined with cisplatin, and the observation group additionally received intravenous injection of astragalus polysaccharides for 10 days, to compare the hemogram before and after treatments between two groups. Results After treatments, the total effective rate of the observation group was 61.81%, significantly higher than that of the control group, the difference was statistically significant (P<0.05); The white blood cell, red blood cell and platelet count reduced in two goups after treatment. Compared with the control group, there was no significant decrease in the observation group. Conclusion Astragalus polysaccharides injection may reduce the marrow suppression induced by radiotherapy and chemotherapy in the treatment of cervical cancer, and it has a protective effect on the bone marrow.