您的位置: 首页 > 2016年9月 第47卷 第5期 > 文字全文
2023年7月 第38卷 第7期11
目录

注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的效果分析

Clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy

来源期刊: 广州医药 | 36-38 发布时间:2021-12-02 收稿时间:2025/11/13 16:55:13 阅读量:13
作者:
关键词:
注射用黄芪多糖宫颈癌放化疗骨髓抑制
Astragalus Polysaccharides InjectionCervical CarcinomaRadiotherapy and ChemotherapyMarrow Suppression
DOI:
10.3969/j.issn.1000-8535.2016.05.013
收稿时间:
2016-06-10 
修订日期:
 
接收日期:
 
引用总数:
0  
目的 探讨注射用黄芪多糖对宫颈癌化疗患者骨髓抑制的影响。方法 选取2012年11月—2015年10月于我院接受治疗的宫颈癌患者110例,随机分为对照组和观察组,每组各55例,两组患者均接受紫杉醇联合顺铂同步放疗,而观察组患者在此基础上接受每日静脉滴注注射用黄芪多糖治疗,连续应用10天。对比分析两组患者的临床疗效以及治疗前后的血象。结果 经过治疗后,观察组的治疗总有效率为61.81%,明显高于对照组的38.18%,差异有统计学意义(P<0.05);两组患者经过放化疗后其白细胞、红细胞和血小板计数均有不同程度的降低,而与对照组相比,观察组患者下降不明显。结论 注射用黄芪多糖可以减轻宫颈癌放化疗所致的骨髓抑制,对骨髓具有一定的保护作用,在临床治疗宫颈癌的过程中值得推广应用。
Objective To explore the clinical effect of astragalus polysaccharides on protecting marrow suppression of cervical carcinoma after chemotherapy. Methods 110 cases of patients with cervical carcinoma treated in our hospital from November 2012 to October 2015 in our hospital were selected and divided into control group and observation group, each group contains 55 cases. Both groups of patients received radiotherapy and chemotherapy of paclitaxel combined with cisplatin, and the observation group additionally received intravenous injection of astragalus polysaccharides for 10 days, to compare the hemogram before and after treatments between two groups. Results After treatments, the total effective rate of the observation group was 61.81%, significantly higher than that of the control group, the difference was statistically significant (P<0.05); The white blood cell, red blood cell and platelet count reduced in two goups after treatment. Compared with the control group, there was no significant decrease in the observation group. Conclusion Astragalus polysaccharides injection may reduce the marrow suppression induced by radiotherapy and chemotherapy in the treatment of cervical cancer, and it has a protective effect on the bone marrow.
1、 柏冬志, 东方, 唐文婷, 等. 黄芪多糖药理作用的研究进展[J]. 黑龙江医学, 2014,27(1): 60-62. 柏冬志, 东方, 唐文婷, 等. 黄芪多糖药理作用的研究进展[J]. 黑龙江医学, 2014,27(1): 60-62.
2、 汤新跃, 蔡长青,廖万清. 注射用黄芪多糖联合三维适形放疗治疗老年非小细胞肺癌疗效观察[J]. 现代医院, 2015,15(9): 30-31. 汤新跃, 蔡长青,廖万清. 注射用黄芪多糖联合三维适形放疗治疗老年非小细胞肺癌疗效观察[J]. 现代医院, 2015,15(9): 30-31.
3、 谈发明, 刘颜, 陈茂华,等. 当归补血汤对肿瘤放、化疗导致的骨髓抑制的保护作用[J]. 湖北中医杂志, 2014,36(8): 77-78. 谈发明, 刘颜, 陈茂华,等. 当归补血汤对肿瘤放、化疗导致的骨髓抑制的保护作用[J]. 湖北中医杂志, 2014,36(8): 77-78.
4、 庞香茹. 中药治疗恶性肿瘤放化疗后骨髓抑制的临床研究[J]. 中医学报, 2011, 26(4): 393-394. 庞香茹. 中药治疗恶性肿瘤放化疗后骨髓抑制的临床研究[J]. 中医学报, 2011, 26(4): 393-394.
5、 LARMOUR, LI, JOBLING TW, GARGETT CE. A Review of Current Animal Models for the Study of Cervical Dysplasia and Cervical Carcinoma[J]. International Journal of Gynecological Cancer, 2015,25(8): 1345-1352. LARMOUR, LI, JOBLING TW, GARGETT CE. A Review of Current Animal Models for the Study of Cervical Dysplasia and Cervical Carcinoma[J]. International Journal of Gynecological Cancer, 2015,25(8): 1345-1352.
6、 李晓虹, 李安群, 沈雪歌,等. 年轻女性恶性肿瘤化疗临床分析[J]. 广州医药, 2016, 47(1): 18-20. 李晓虹, 李安群, 沈雪歌,等. 年轻女性恶性肿瘤化疗临床分析[J]. 广州医药, 2016, 47(1): 18-20.
7、 叶学松. 同步化疗治疗食管癌的临床疗效及毒副作用[J]. 中国医药指南, 2013,22(34): 169-170. 叶学松. 同步化疗治疗食管癌的临床疗效及毒副作用[J]. 中国医药指南, 2013,22(34): 169-170.
8、 胡芝, 徐律, 黄一统,等. 多西他赛联合奈达铂同步放化疗治疗中晚期宫颈癌的临床疗效分析[J]. 肿瘤学杂志, 2014, 20(10): 829-832. 胡芝, 徐律, 黄一统,等. 多西他赛联合奈达铂同步放化疗治疗中晚期宫颈癌的临床疗效分析[J]. 肿瘤学杂志, 2014, 20(10): 829-832.
上一篇
下一篇
出版者信息








《广州医药》公众号
目录