专题:人工智能与医学
目的本文聚焦DeepSeek这一国产人工智能技术,结合护理临床实践,系统探讨其在护理场景中的应用潜力、现存问题及应对策略。方法检索国内外相关文献,与现有通用人工智能技术对比,进行综述,并提出思考和建议。结果预计DeepSeek在护理文书自动化、个性化护理方案生成、临床决策支持、护理质控及教育培训等提供适配应用路径,针对性的服务和解决方案等。结论DeepSeek可通过多模态技术整合与跨平台互补策略,推动护理服务向智能化、精准化方向发展,为缓解护理人力短缺、优化资源分配提供新思路。
ObjectiveThis study focuses on DeepSeek,a domestic artificial intelligence technology,systematically exploring its application potential,existing issues,and targeted strategies in nursing clinical scenarios through integration with practical nursing care contexts.MethodsRelevant literatures from both domestic and international sources were collected,compared with existing Artificial General Intelligence(AGI)technologies,to conduct a review,and propose reflections and recommendations.ResultsThrough literature review and technical comparisons,the results proposed specific application paths for DeepSeek in scenarios such as automated nursing documentation,personalized care plan generation,clinical decision support,quality control,and education.It further addressed issues including data privacy,ethical risks,and technical limitations.ConclusionsThe findings suggest that DeepSeek can integrate multimodal technologies and cross-platform complementary strategies to promote intelligent and precise nursing services,offering innovative solutions to alleviate nursing shortages and optimize resource allocation.
专题:人工智能与医学
传统的结肠镜检查质量评估方式具有主观性强、费时费力等缺点。近年来,人工智能(AI)技术在结肠镜检查质量控制方面展现出客观性、即时性、全面性等优势,具有广阔的应用前景。文章全面探讨了AI在结肠镜检查质量控制中的多个应用场景,包括评估肠道准备质量、记录退镜时间、息肉识别和分类、预测早期结直肠癌浸润深度等方面,并通过具体的研究案例和数据分析了AI技术的有效性和优势。AI技术有望在提升结肠镜检查质量、促进结直肠癌的早诊早治方面发挥更加重要的作用,但面对技术、伦理及法规等多方面的挑战,未来需要持续努力,不断优化算法,加强跨学科合作,推动AI技术在医疗领域的健康、快速发展。
Traditional colonoscopy quality assessment methods have strong subjectivity and are time-consuming.In recent years,artificial intelligence technology has shown objectivity,timeliness,and comprehensiveness in colonoscopy quality control,with broad application prospects.This article comprehensively explores multiple application scenarios of AI in colonoscopy quality control,encompassing assessments of bowel preparation quality,recording of withdrawal times,polyp identification and classification,and prediction of early colorectal cancer invasion depth.Through specific research cases and data analysis,the effectiveness and advantages of AI technology are elucidated.AI technology is expected to play an increasingly significant role in enhancing the quality of colonoscopy and promoting early diagnosis and treatment of colorectal cancer.However,facing challenges from technology,ethics,regulations,and other aspects,continued efforts are needed in the future to continuously optimize algorithms,strengthen interdisciplinary collaboration,and promote the healthy and rapid development of AI technology in the medical field.
论著
目的 探讨免疫治疗联合化学治疗(化疗)对晚期非小细胞肺癌(NSCLC)患者淋巴免疫及生活质量的影响,为临床进一步治疗提供参考。方法 选择2021年6月—2023年6月天津市滨海新区大港医院收治的晚期NSCLC患者120例进行研究,按抽签法分为干预组及对照组,每组60例,对照组采取单纯化疗方案,干预组采取免疫联合化疗方案,对比两组临床疗效、药物不良反应,治疗前后免疫功能(CD3+、CD4+、CD8+)、糖类抗原199(CA199)、糖类抗原 125(CA125)、血清癌胚抗原(CEA)水平及健康状态调查表(QOL)评分。结果 干预组患者治疗总有效率高于对照组(68.33%>41.67%,P<0.05);治疗后干预组患者CD3+、CD4+比例高于治疗前及对照组治疗后,CD8+比例低于治疗前及对照组治疗后(P<0.05);治疗后干预组血清CA199、CA125、CEA水平均低于治疗前及对照组治疗后(P<0.05);干预组药物不良反应发生率为16.67%,对照组为36.67%,干预组低于对照组(P<0.05);治疗后干预组QOL各维度评分高于对照组及治疗前(P<0.05)。结论 与单纯化疗相比,免疫联合化疗治疗晚期NSCLC患者,能有效降低肿瘤标志物水平,改善患者免疫指标,减轻药物不良反应,提高患者疗效及生活质量。
Objective To explore the effect of immunotherapy combined with chemotherapy on lymphatic immunity and quality of life of patients with advanced non-small cell lung cancer(NSCLC),and to provide reference for further clinical treatment. Methods A total of 120 patients with NSCLC from June 2021 to June 2023 were selected and divided into observation group and control group evenly according to the method of drawing lots,control group was treated with chemotherapy,the observation group was treated with immunotherapy combined with chemotherapy,and the clinical efficacy and adverse drug reactions were compared between the two groups.Before and after treatment,immune function(CD3+,CD4+,CD8+),carbohydrate antigen 199(CA199),carbohydrate antigen 125(CA125),serum carcinoembryonic antigen(CEA)levels and health status questionnaire(QOL-RRB- scores)were measured.Results The total effective rate in the observation group was significantly higher than that in the control group(68.33%>41.67%,P<0.05).After treatment,the ratios of CD3+ and CD4+ in the observation group were significantly higher than those before treatment and control group after treatment,and the ratio of CD8+ was significantly lower than that before and after treatment in the control group(P<0.05).After treatment,the serum levels of CA199,CA125 and CEA in the observation group were lower than those before and after treatment in the control group(P<0.05).The incidence of adverse drug reactions was 16.67% in the observation group and 36.67% in the control group,which was significantly lower in the observation group than in the control group(P<0.05).After treatment,the QOL scores in the observation group were significantly higher than those in the control group and before treatment(P<0.05).Conclusions Compared with chemotherapy alone,immunotherapy combined with chemotherapy can effectively reduce the levels of tumor markers,improve the immune indexes of patients,reduce the adverse drug reactions,and improve the efficacy and quality of life of patients with advanced NSCLC.
论著
目的 对比乏白细胞富血小板血浆(LP-PRP)与富白细胞富血小板血浆(LR-PRP)联合体外冲击波疗法(ESWT)治疗慢性非止点跟腱腱病(NIAT)的临床价值。方法 选取2021年12月—2023年12月赣州市人民医院收治的80例慢性NIAT患者,以随机数表法分为两组,即对照组和观察组各40例,观察组予LP-PRP联合ESWT治疗,对照组予LR-PRP联合ESWT治疗;于治疗前、第一次治疗后1个月、3个月比较两组疼痛度[视觉模拟量表(VAS)评分]、跟腱病变程度[维多利亚体育研究所跟腱评估问卷(VISA-A)]、跟腱功能(Arner-Lindholm跟腱功能评分),并比较两组并发症的发生率。结果 两组在治疗后1个月、3个月的VAS评分下降,VISA-A评分升高,且观察组治疗后3个月的VAS评分(1.05±0.31)分低于对照组的(1.82±0.45)分,VISA-A评分(83.35±5.58)分高于对照组的(76.28±5.35)分(F组间与时点交互=338.478、106.663,均P<0.05);治疗后3个月,观察组跟腱功能(优、良、差各有24、13、3例)优于对照组(优、良、差各有14、16、10例),差异有统计学意义(Z=2.529,P=0.012)。两组治疗后1个月时VAS评分、VISA-A评分及跟腱功能比较差异无统计学意义(均P>0.05)。结论 与LR-PRP比较,LP-PRP联合ESWT治疗慢性NIAT更有利于减轻患者跟腱疼痛度及病变程度,改善患者跟腱功能。
Objective To compare the clinical value of leukocyte-poor platelet rich plasma(LP-PRP)and leukocyte-rich platelet rich plasma(LR-PRP)combined with extracorporeal shock wave therapy(ESWT)in the treatment of chronic non -insertional Achilles tendinopathy(NIAT).Methods Eighty patients with chronic NIAT admitted to Ganzhou People's Hospital from December 2021 to December 2023 were randomly divided into two groups using a random number table method:a control group and an observation group,with 40 patients in each group.The observation group received LP-PRP combined with ESWT treatment,while the control group received LR-PRP combined with ESWT treatment.The pain level(Visual Analog Scale[VAS]score),degree of Achilles tendon lesion(Victorian Institute of Sports Assessment-Achilles tendinopathy questionnaire[VISA-A]),and Achilles tendon function(Arner Lindholm Achilles tendon function score)between the two groups were compared before treatment,one month after the first treatment,and three months after treatment,as well as the incidence of complications between the two groups.Results The VAS scores of both groups decreased and the VISA-A scores increased one and three months after treatment.The VAS score of the observation group(1.05±0.31)was lower than that of the control group(1.82±0.45)three months after treatment,while the VISA-A score of the observation group(83.35±5.58)was higher than that of the control group(76.28±5.35)(interaction between group and time point F=338.478,106.663,both P<0.05).After three months of treatment,the Achilles tendon function of the observation group(24 cases of excellent,13 cases of good,and three cases of poor)was better than that of the control group(14 cases of excellent,16 cases of good,and 10 cases of poor),and the difference was statistically significant(Z=2.529,P=0.012).There was no statistically significant difference in VAS score,VISA-A score,and Achilles tendon function between the two groups one month after treatment(all P>0.05).Conclusions Compared with LR-PRP,LP-PRP combined with ESWT was more beneficial in reducing the degree of Achilles tendon pain and lesions in patients with chronic NIAT,and improving Achilles tendon function.
论著
目的 探讨肝脏衰弱程度联合肝功能分级预测肝硬化患者肝病复合不良事件的价值,作为识别和干预不良结局的依据。方法 选择2022年12月—2023年12月医院接收的肝硬化患者80例进行研究,随访6个月观察患者不良事件发生情况,将出现2个及以上肝病并发症的肝病复合不良事件患者25例作为观察组,将出现1个肝病并发症或未出现并发症的患者55例作为对照组,比较两组患者的基本资料、实验室指标、营养指标、体力活动水平、肝脏衰弱指数(LFI)、肝功能Child-Turcotte-Pugh(CTP)评分,采用单因素和多因素Cox回归分析评估肝硬化患者肝病复合不良事件的危险因素,使用受试者工作特征(ROC)曲线下面积评估LFI联合CTP评分预测肝硬化患者肝病复合不良事件的价值。结果 观察组年龄、丙氨酸氨基转移酶(ALT)高于对照组,红细胞计数(RBC)、血红蛋白(Hb)、血肌酐(Scr)、总胆红素(TBIL)、步速、小腿围低于对照组(t分别为4.235、6.500、3.826、3.989、4.289、8.878、2.474,均P<0.05)。观察组营养风险48.00%、LFI≥4.5分52.00%、CTP分级B/C级76.00%高于对照组18.18%、14.55%、27.27%(χ2分别为7.664、12.454、16.699,均P<0.05)。单因素Cox回归分析显示年龄、ALT、营养风险、LFI≥4.5分、CTP分级B/C级、RBC、Scr、TBIL、Hb、步速、小腿围为肝硬化患者发生肝病复合不良事件的危险因素(HR分别为2.251、1.578、1.626、1.981、1.715、1.428、1.443、1.419、1.336、1.332、1.254,均P<0.05)。多因素Cox回归分析显示年龄、营养风险、LFI≥4.5分、CTP分级B/C级为肝硬化患者发生肝病复合不良事件的独立危险因素(HR分别为2.275、1.746、2.025、1.895,P均<0.05)。ROC曲线结果显示LFI、CTP、LFI联合CTP预测肝硬化患者肝病复合不良事件的AUC分别为0.82、0.79、0.88(P<0.05)。结论 年龄、肝脏衰弱、CTP分级B/C级、营养风险为肝硬化患者肝病复合不良事件的危险因素,肝脏衰弱程度联合肝功能分级预测肝硬化患者肝病复合不良事件具有更高的效能。
Objective To explore the value of predicting liver disease complex adverse events in patients with liver cirrhosis by combining the degree of liver frailty with liver function grading,as a basis for identifying and intervening in adverse outcomes.Methods A study was conducted on 80 patients with liver cirrhosis admitted to the hospital from December 2022 to December 2023. Patients were followed up for six months to observe the occurrence of adverse events.Twenty-five patients with liver disease complex adverse events with two or more liver disease complications were selected as the observation group,and 55 patients with one or no liver disease complication were selected as the control group.The basic information,laboratory indicators,nutritional indicators,physical activity levels,liver frailty index(LFI),Child Turcotte Pugh(CTP)scores,univariate and multivariate Cox regression analysis were used to evaluate the risk factors for liver disease complex adverse events in liver cirrhosis patients.The value of combining LFI and CTP score in predicting liver disease complex adverse events in patients with liver cirrhosis was assessed by Receiver Operating Characteristic(ROC)curve area.Results The age,alanine aminotransferase(ALT),red blood cell count(RBC),hemoglobin(Hb),serum creatinine(Scr),total bilirubin(TBIL),walking speed,and calf circumference of the observation group were higher than those of the control group(t=4.235,6.500,3.826,3.989,4.289,8.878,2.474,all P<0.05).The nutritional risk of the observation group was 48.00%,LFI score≥4.5 was 52.00%,CTP grade B/C was 76.00%,which was higher than that of the control group at 18.18%,14.55%,and 27.27%(χ2=7.664,12.454,16.699,all P<0.05).Univariate Cox regression analysis showed age,ALT,nutritional risk,LFI ≥ 4.5,CTP grade B/C,RBC,Scr,TBIL,Hb,step speed and calf circumference were risk factors for the occurrence of liver disease complex adverse events in patients with liver cirrhosis(HR values=2.251,1.578,1.626,1.981,1.715,1.428,1.443,1.419,1.336,1.332,1.254,all P<0.05).Multivariate Cox regression analysis showed that age,nutritional risk,LFI ≥ 4.5,and CTP grade B/C were independent risk factors for liver disease complex adverse events in patients with liver cirrhosis(HR values=2.275,1.746,2.025,1.895,all P<0.05).The ROC curve results showed that the AUC of LFI,CTP,and LFI combined with CTP in predicting liver disease composite adverse events in patients with liver cirrhosis were 0.82,0.79,and 0.88,respectively(P<0.05).Conclusions Age,liver frailty,CTP grade B/C,and nutritional risk are risk factors for liver disease complex adverse events in patients with liver cirrhosis.The combination of LFI and liver function grade has higher efficacy in predicting liver disease complex adverse events in patients with liver cirrhosis.
论著
目的 对入住重症监护病房(ICU)重症孕产妇患者的病种特征和住院费用进行分析。方法 从医院信息管理系统中搜索2009—2019年广州市某省级重症孕产妇救治中心ICU的重症孕产妇住院病例,对病例资料进行描述性流行病学分析。结果 2009—2019年该救治中心ICU共收治重症孕产妇1 616例,病种排名前五位依次为心血管疾病430例(26.61%)、血液及造血器官疾病310例(19.18%)、妊娠期特定并发疾病287例(17.76%)、消化系统疾病218例(13.49%)、呼吸系统疾病110例(6.81%)。患者经济负担中位数排名前五位依次为肌肉骨骼系统和结缔组织疾病(62 252.60元)、消化系统疾病(61 684.41元)、感染性疾病(42 945.70元)、血液及造血器官疾病(40 403.52元)、神经系统疾病(40 055.93元)。结论 入住ICU内的重症孕产妇以心血管疾病、血液及造血器官疾病为主,经济学分析表明肌肉骨骼系统和结缔组织疾病造成的经济损失较大。
Objective To analyze the disease characteristics and hospitalization expenses of critically ill maternal patients in intensive care unit(ICU).Methods Hospitalized cases of severe maternal disease in ICU of a provincial critical care center in Guangzhou from 2009 to 2019 were searched from the hospital information management system,and case data was analyzed by descriptive epidemiology.Results From 2009 to 2019,a total of 1616 critically ill maternal patients received intensive care treatment at this center.The predominant diseases observed were cardiovascular disorders(26.61%),blood and hematopoietic organ diseases(19.18%),specific pregnancy-related complications(17.76%),gastrointestinal ailments(13.49%),and respiratory disorders(6.81%).Among the top five patient groups,the median economic burden was the highest in musculoskeletal system and connective tissue diseases(62 252.600 yuan),followed by digestive system diseases(61 684.410 yuan),infectious diseases(42 945.700 yuan),blood and hematopoietic organ diseases(40 403.515 yuan),and nervous system disorders(40 055.930 yuan).Furthermore,a discernible correlation between hospitalization cost and length of stay was identified.Conclusions Cardiovascular diseases and disorders of blood and hematopoietic organs are the primary causes for maternal admissions to ICU.Economic analysis shows that musculoskeletal system and connective tissues diseases cause bigger economic loss .
医学教育
目的 探讨基于迷你临床演练评估(Mini-CEX)的可视化思维导图联合案例教学在全科住院医师规范化培训中的应用效果。方法 选取参加全科住院医师规范化培训的52例学员并分为试验组(n=26)和对照组(n=26)。对照组采取以案例讲授为主的传统教学模式,试验组采取基于Mini-CEX的可视化思维导图联合案例教学模式。对比两组Mini-CEX评分、考核成绩及教学满意度。结果 试验组Mini-CEX测评的问诊技巧、体格检查、临床判断、诊治能力、技能操作及整体表现得分均高于对照组(P<0.05)。试验组理论知识[(86.89±4.75)分 vs (82.96±4.87分)]、专业技能[(84.20±3.46)分 vs (70.18±4.93)分]及病历书写成绩[(80.64±5.26)分 vs (75.58±5.94)分]均高于对照组(t分别为2.678、13.685、2.764,P分别为0.009、<0.001、0.007)。试验组住院医师教学满意度高于对照组(P<0.05)。结论 基于Mini-CEX的可视化思维导图联合案例教学模式用于全科住院医师规范化培训,有助于提高教学效果及教学满意度。
Objective To evaluate the effect of visual mind mapping combined with case teaching based on mini-clinical evaluation exercise(Mini-CEX)for standardized training of general practitioners.Methods A total of 52 students who participated the standardized training of general practitioners were selected and divided into an experimental group(n=26)and a control group(n=26).The control group adopted the traditional teaching mode based on case teaching and the experimental group adopted the visual mind mapping combined with case teaching based on Mini-CEX.The Mini-CEX score,assessment results and teaching satisfaction of two groups were compared.Results The interrogation skills,physical examination,clinical judgment,diagnosis and treatment ability,skill operation and overall performance of Mini-CEX in experimental group were higher than control group(P<0.05).Theoretical knowledge score([86.89±4.75] vs [82.96±4.87]),professional skills score([84.20±3.46] vs [70.18±4.93])and medical record writing score([80.64±5.26] vs [75.58±5.94])of experimental groups were higher than control group(t=2.678,13.685,2.764,P=0.009,<0.001,0.007).The teaching satisfaction of residents in experimental group was higher than control group(P<0.05).Conclusions The visual mind mapping combined with case teaching based on Mini-CEX for standardized training of general practitioners is helpful to improve teaching effect and teaching satisfaction.
论著
目的 探讨单次根管疏通填充对牙体牙髓病患者的填充效果及龈沟液炎症指标的影响。方法 选择2023年8月—2024年2月天津市人民医院接收的牙体牙髓病患者84例进行研究,采用随机数字表法分为两组,各42例。对照组采取多次根管疏通填充,观察组采取单次根管疏通填充,比较2组填充效果、治疗效果、龈沟液炎症指标、口腔健康和功能指标、并发症情况。结果 观察组欠填、恰填、超填比例与对照组比较无统计学意义(χ2分别为0.262、1.615、0.512,P分别为0.608、0.203、0.474)。观察组的总有效率为97.62%,高于对照组80.95%(χ2=6.098,P=0.014)。治疗后,观察组龈沟液白细胞介素IL-1β、IL-17A、IL-35、肿瘤坏死因子-α水平低于对照组(t分别为3.271、3.028、2.699、2.968,P分别为0.002、0.003、0.008、0.004)。治疗后,观察组龈沟出血指数、牙龈指数低于对照组,咬合力、咀嚼效率高于对照组(t分别为2.311、2.686、2.262、2.776,P分别为0.023、0.009、0.026、0.007)。观察组并发症发生率4.76%低于对照组21.43%(χ2=5.126,P=0.024)。结论 牙体牙髓病采取单次根管疏通填充治疗可保证恰当的填充效果,取得良好的治疗效果,而且减轻龈沟液炎症反应,促进口腔健康和功能改善,并发症较少,安全性高,值得推广。
Objective To explore the effects of one-time root canal dredging and filling on the filling effect and gingival crevicular fluid inflammation indexes in patients with endodontic disease.Methods A total of 84 cases of endodontic patients admitted to the Tianjin People's Hospital from August 2023 to February 2024 were chosen and separated into the control group(n=42,multiple-time root canal dredging and filling)and the observation group(n=42,one-time root canal dredging and filling)by random number table method.The filling effect,therapeutic effect,gingival creval fluid inflammation indicators,oral health and function indicators,and complications were compared.Results The underfilling,accurate filling and overfilling showed no significant difference between the two groups(χ2=0.262,1.615,0.512,P=0.608,0.203,0.474).The total effective rate of observation group was 97.62%,higher than that of control group 80.95%(χ2=6.098,P=0.014).After treatment,levels of interleukin(IL)-1β,IL-17A,IL-35 and tumor necrosis factor-α in gingival crevicular fluid of observation group were lower(t=3.271、3.028、2.699、2.968,P=0.002、0.003、0.008、0.004).After treatment,the sulcus bleeding index and gingival index of the observation group were lower,and the biting force and mastication efficiency were higher(t=2.311、2.686、2.262、2.776,P=0.023、0.009、0.026、0.007).The complication rate in the observation group was 4.76%,lower than that in the control group 21.43%(χ2=5.126,P=0.024).Conclusions A one-time root canal dredging and filling treatment for endodontic diseases can ensure proper filling effect,achieve good therapeutic effect,reduce gingival crevicular fluid inflammation,promote oral health and function improvement,with fewer complications,high safety,which is worthy of promotion.
论著
目的 血清同型半胱氨酸(Hcy)水平与慢性肾脏病(CKD)的进展相关,但中年人群的非线性关联研究较少,本研究旨在寻找慢性肾脏病危险因素。方法 本研究基于NHANES 1996—2006年数据,纳入5 361例45~65岁参与者,以估算肾小球滤过率(eGFR)<60 mL/(min·1.73 m2)和尿白蛋白/肌酐比值(uACR)≥30 mg/g评估肾功能下降。结果 通过逻辑回归及平滑曲线拟合分析发现,Hcy每升高1 µmol/L,eGFR降低的风险增加8%(OR=1.08,95%CI:1.06~1.10),uACR升高的风险增加2%(OR=1.02,95%CI:1.00~1.04)。非线性分析显示,Hcy对eGFR的阈值效应拐点为13.4 µmol/L(拐点左侧OR=1.59,95%CI:1.49~1.70;右侧无显著关联)。亚组分析表明,性别、高血压、糖尿病等协变量无交互作用,然而,在敏感性分析中,糖尿病患者中Hcy与eGFR降低的关联更强(交互P=0.015 8)。结论 本研究提示,控制Hcy水平或可延缓美国中年人群(尤其是糖尿病患者)的肾功能衰退。
Objective Elevated serum homocysteine(Hcy)levels are linked to chronic kidney disease(CKD)progression,yet the nonlinear relationship in middle-aged populations remains underexplored.Methods This study analyzed data from 5 361 participants aged 45-65 years in the NHANES 1996-2006 cohort.Renal dysfunction was defined as an estimated glomerular filtration rate(eGFR)<60 mL/min/1.73 m2 and urinary albumin-to-creatinine ratio(uACR)≥30 mg/g.Results Logistic regression and smoothed curve fitting revealed that each 1 µmol/L increase in Hcy elevated the risk of reduced eGFR by 8%(OR=1.08,95% CI:1.06-1.10)and uACR by 2%(OR=1.02,95% CI:1.00-1.04).A nonlinear threshold effect was identified at 13.4 µmol/L,with a stronger association below this threshold(OR=1.59,95% CI:1.49-1.70)and no significant effect above it.Subgroup analyses showed no interactions with gender or hypertension,but a stronger Hcy-eGFR association was observed in diabetics(interaction P=0.0158).Conclusions These findings suggest that controlling Hcy levels may mitigate renal decline,particularly in diabetic populations,warranting further causal investigations.
论著
目的 探讨中医药治疗小儿腺样体肥大(AH)的研究现状、研究热点及趋势,为本领域研究者提供借鉴。方法 检索中国知网(CNKI)数据库从2005年1月1日至2024年1月31日中医药治疗小儿腺样体肥大的相关文献。运用Excel 2019分析其发文量,运用CiteSpace 6.2.R6软件分析其作者、机构、关键词。结果 共纳入文献395篇,年发文量整体呈现波动上升的趋势;发文量最多的作者为姜之炎;发文量最多的研究机构为山东中医药大学。初步形成了以姜之炎、俞景茂、阎兆君为核心的研究团队;研究机构以中医类院校及其附属医院为主。高频关键词提示当前研究热点前三位为中医药治疗方法、临床疗效。结论 AH领域研究内容主要以内治法、外治法、作用机制为主;研究热点逐渐从临床研究转向作用机制等实验研究;应用“数据挖掘”“网络药理学”等计算机技术研究AH会成为趋势。
Objective To explore the research status,research hotspots,and trends of traditional Chinese medicine in the treatment of adenoid hypertrophy in children,to provide a reference for researchers in this field.Methods The relevant literature on the treatment of adenoid hypertrophy in children with traditional Chinese medicine was searched in the CNKI database from January 1,2005,to January 31,2024.Excel 2019 was applied to analyze the number of published papers,and CiteSpace 6.2.R6 software was applied to analyze its authors,institutions,and keywords.Results A total of 395 papers were included,and the annual number of papers showed a fluctuating upward trend.The author with the largest number of papers was JIANG Zhiyan.Shandong University of Traditional Chinese Medicine was the research institution with the largest number of papers.The core research teams including JIANG Zhiyan,YU Jingmao,and YAN Zhaojun were initially formed.The research institutions were mainly Chinese medicine colleges and their affiliated hospitals.High-frequency keywords suggest that the current top three research hotspots were traditional Chinese medicine treatment methods,clinical efficacy.Conclusions The research content in this field is mainly based on internal treatment,external treatment,and mechanism.The focus has gradually shifted from clinical research to experimental research such as mechanism.The application of computer technologies such as “data mining” and “network pharmacology” for this disease will become a trend.