论著
目的 探讨自体心包膜组织对急性心肌梗死大鼠心脏功能的影响。方法 筛选合格的模型动物随机分为三组:心包去除组:仅去除心包膜;心梗组:前降支结扎法建立大鼠心肌梗死模型3周后仅开胸;移植组:前降支结扎法建立大鼠心肌梗死模型,3周后将心包膜移植于心肌梗死及周边区。实验4周后,通过心动图评价实验动物心脏功能,使用Masson染色检测动物心肌梗死大小,通过免疫荧光评价动物心肌存活率、观察血管新生状况,Western blot检测Caspase-3蛋白/Bcl-2基因表达情况。结果 4周后,心包去除组大鼠的心电图监测结果未见有室性颤动;而心梗组、心梗+移植组均有非致死性室性颤动。相比心梗组,心梗+移植组改善了心功能,降低了心肌凋亡指数,免疫Bcl-2蛋白表达升高,而Caspase-3蛋白表达降低。结论 提示自体心包膜移植不会导致恶性室性心律失常,相对有较高的安全性;并能促进心肌梗死细胞恢复心功能,其改善机制可能与通过修补心室重构途径同时抑制缺血区域细胞凋亡有关。
Objective To explore the effect of autologous pericardial transplantation for treating the myocardial infarction (MI) in experimental rats. Methods 30 SD rats were randomly divided in to three equal parts: Pericardial removal group (PR group): only pericardium tissue was removed; Myocardial infarction group (MI group): the anterior descending branch ligation method established a rat model of myocardial infarction and only opened the chest after 3 weeks. Autologous pericardium transplantation (APT group): After established the MI model of SD rats, 3 weeks later, the autologous pericardial patch was harvested and transplanted to infarcted zone. Four weeks after the surgery, the cardiac function and serum biochemistry were analyzed for all the experimental rats. The cardiac function was evaluated by echocardiography, which the size of the infarction were examined by Masson staining, the survival time of transplanted autologous pericardial and angiogenesis were measured by immunohistochemistry, the protein expressions of Caspase and the gene expressions of Bcl were examined by Western blot analysis. Results 4 week after the 2nd operation, no ventricular fibrillation was detected in the ECG of PR group. Fatal ventricular fibrillation wasn't detected in the ECG of MI group and APT group. Compared with MI group, APT group improved cardiac function and decreased myocardial apoptosis index(P<0.05),which similar to PR group. APT group has the higher density of angiogenesis at infracted area to MI group but less than that of PR group. PT group had decreased protein expressions of Caspase-3 and the expressions of Bcl-2 were decreased. Conclusion Autologous pericardial transplantation could recover myocardial infarction cells, which will improve the cardiac function in experimental rats with MI.
论著
目的 分析15例腹腔妊娠患者的临床病例特点,为临床工作提供参考依据,进一步减少漏诊及误诊的情况。方法 收集我院2002年1月—2018年6月期间住院治疗的腹腔妊娠患者的临床病例资料。回顾性分析并总结患者的临床诊治特点。通过t检验,进一步比较腹腔镜与腹式手术患者围手术期情况是否存在统计学差异。结果 1例B超检查提示大网膜妊娠可能;另1例入院前外院B超提示腹腔妊娠,孕8+周单活胎;其余13例患者术前B超提示宫内未见孕囊,子宫旁有包块,提示异位妊娠可能,术前未能明确腹腔妊娠。14例患者行手术治疗,另1例行介入穿刺保守治疗。术中探查发现腹腔妊娠病灶种植部位:位于大网膜5例,位于盆腔9例(膀胱区右下方盆壁1例,子宫直肠窝右侧直肠表面1例,右侧宫骶韧带2例,子宫下段前壁瘢痕处右缘1例,偏左侧肠管与子宫粘连之间1例、右侧盆壁1例、子宫直肠窝1例、子宫左侧圆韧带起始端1例),位于腹腔1例(腰3椎体前方、腹主动脉与下腔静脉之间)。结论 腹腔妊娠的异位妊娠病灶种植部位非常广泛,超声检查需进一步扩大检查范围。必要时可选择MRI或CT检查准确定位,减少漏诊及误诊的情况。
Objective To analysis and summary clinical characteristics of 15 patients who were diagnosed with abdominal pregnancy,which supply reference for clinical work. Methods 15 cases who were diagnosed with abdominal pregnancy and admitted to Guangdong Women and Children hospital between January 2002 and June 2018 were identified. Retrospective analysis was used to summarize the clinical characteristics of diagnosis and treatment in 15 patients. Test statistics used Student's t test to find if there was statistical difference between laparoscopic and abdominal surgery patients in perioperative period. Results One case was likely diagnosed with greater omentum pregnancy by type B ultrasound. Another one patient was diagnosed with abdominal pregnancy which has 8+ weeks pregnant single live fetus by type B ultrasound in other hospital prior to hospitalization.The B ultrasound tests of the other 13 patients showed there were no sac in uterus and enclosed mass beside uterus which were diagnosed with ectopic pregnancy, but not positive diagnosis with abdominal pregnancy.Surgery was performed for 14 patients.We found more different sites where gestational sacs plant in abdominal pregnancy patients in operation, 5 cases sacs planted in greater omentum, 9 cases sacs planted in pelvic cavity including 1 case sac planted in pelvic wall bottom-right bladder,1 case sac planted in rectum outside right-hand of Douglas pouch,2 cases sacs planted in right utero-sacral ligament,1 case sac planted in right-side of scar in lower uterus segment,1 case sac planted in adhesive tissue between the lift intestinal canal and uterus,1 case sac planted in right pelvic cavity,1 case sac planted in Douglas pouch,1 case sac planted in initiating terminal of the lift round ligament of uterus. The inteventional puncture with medical treatment was supply for only 1 patient,CT test showed the sac planted in abdominal: ahead of third lumbar vertebra between abdominal aorta and inferior vena cava. Conclusion There are more sites where gestational sacs can plant in abdominal pregnancy patients. Ultrasound is first choice for patient who was considered ectopic pregnancy and better to expansion the inspection range. MRI or CT may find sacs plant site who was considered abdominal pregnancy which may reduce missed diagnosis and misdiagnosis. Surgery is first performed who was diagnosed with abdominal pregnancy. Medical treatment for patients who vital signs are stable.
论著
早期干预是预防和减少早产儿神经系统损伤的有效措施,可以促进早产儿的正常发育并减轻神经系统伤残的发生,对提高儿童综合素质和家庭幸福都至关重要。在早产儿早期干预过程中存在与医学伦理原则不相适应的方面,如医疗设施不足、医疗措施不当、专业人员不足,早产儿干预预后的不确定性,治疗时机与家长经济及遵医行为之间的冲突,家长知情选择和知情同意不足等,本文结合医学伦理学的观点对0~3岁早产儿在早期干预中存在的问题进行分析并提出相应的建议。
Early intervention is an effective measure to prevent and reduce the nervous system injury in preterm infants,It can promote the normal development of preterm infants and reduce the occurrence of the nervous system disability.It is vital to improve the comprehensive quality of children and family quality of life. In the stage of premature infant intervention,there are some aspects that are incompatible with the medical ethics principle,i.e. inadequate medical facilities,improper medical measures,lack of professionals,premature infants intervention prognosis uncertainty,the conflict between the timing of treatment and the parents' economic and compliance behaviors,parents' informed choice and informed consent. etc. This paper analyzes the problems in early intervention of 0~3 year old preterm infants and puts forward corresponding suggestions according to the viewpoint of medical ethics.
论著
目的 了解南昌市某政府机关退休人员的健康状况,为制定有针对性的疾病防治措施提供依据。方法 根据南昌大学医院体检科常规体检项目,于2016—2018年对南昌市某政府机关退休职工进行健康体检,分析体检异常所占比例,采用χ2检验比较两样本率。结果 腹部彩超、甲状腺彩超、血脂、幽门螺杆菌(HP)、心电图、肝肾功能、宫颈刮片与白带(女)、血糖、肿瘤指标等为主要异常指标。2016—2018年的腹部彩超异常率分别高达82.98%、88.64%和82.95%,腹部彩超异常者中前列腺增生、脂肪肝和胆道系统异常所占比例较高。腹部彩超异常比例男性高于女性,甲状腺彩超和肿瘤指标异常比例女性高于男性(P<0.05)。结论 该政府机关退休职工健康体检指标异常所占比例较高,需要建立健康档案数据库进行健康管理,并对体检指标异常者安排定期复检,以实现对疾病的“早发现,早诊断,早治疗”。
Objective To understand the health status of retired people in a government agency in Nanchang city,and to provide evidence for the prevention and treatment of diseases. Methods According to the routine physical examination items of the department of physical examination of Nanchang university hospital,the health examination of retired staffs of a government agency in Nanchang city from 2016 to 2018 was carried out. The proportion of abnormal physical examination was analyzed,and the rate of two samples was compared by χ2 test. Results Abdominal ultrasound,thyroid ultrasound,blood lipid,helicobacter pylori (HP),electrocardiogram,liver and kidney function,cervical scraper and leucorrhea (female),blood sugar,tumor index were the main abnormal indexes. The abnormal rate of color Doppler ultrasound was as high as 82.98% and 82.95%,respectively. The proportions of benign prostatic hyperplasia,fatty liver and abnormal biliary system were higher in the patients with abnormal abdominal color Doppler ultrasound. The abnormal rate of abdominal color Doppler ultrasound was higher in male than that in female,and the abnormal rate of thyroid ultrasound and tumor index were higher in female than that in male (P< 0.05). Conclusion The proportions of abnormal health examination indexes of retired staffs in this government agency are relatively high. It is necessary to establish a health record database for health management,and arrange periodic reexamination for those who have abnormal physical examination indexes in order to realize importance of early detection and early diagnosis of diseases,and have early treatment.
论著
目的 对江门市新会区会城街道的严重精神障碍患者监护人进行守护APP干预并评价干预效果影响。方法 以会城街道辖区内登记在国家精神障碍信息系统1 488在册精神障碍患者作为研究对象,随机抽取分为安装守护APP组1 084例和无安装守护APP组404例。安装组通过监护人使用守护APP实现责任医生对患者进行动态监护和实时监护,提供免费咨询、心理干预、服药指导及随访管理服务;无安装组采用常规随访康复管理措施干预。干预满一年后对比分析两组患者康复措施落实情况、服药依从性(治疗率)、病情及社交改善情况、复发住院率、肇事肇祸率及家属疾病知识知晓情况等指标。结果 安装守护App组患者服药依从性(治疗率)及康复措施落实率高于无安装组,家属对精神疾病知识知晓良好率较高;干预后安装组患者的SCL-90评分及心理社交功能评估表评分改善情况优于无安装组,复发住院率和肇事肇祸率明显较低,以上差异均有统计学意义。结论 守护APP平台帮助医生与监护人把严重精神障碍患者的监护工作真正落到实处,康复效果优于传统的康复方法,值得进一步推广应用。
Objective Guardianship APP intervention was conducted for the guardians of severe mental disorders in Huicheng,Xinhui district,Jiangmen city and the effect of intervention was evaluated. Methods 1 488 psychiatric patients in the unit area were taken as the research objects,which were randomly divided into the guardian APP installation group of 1084 cases and the non - installation group of 404 cases. The installation group uses guardian APP to realize the dynamic guardianship and real-time monitoring of the patients,and we provided free charge consultation,psychological intervention,medication guide,case tracking and follow-up management services. The non installation group adopted the routine rehabilitation management measures after discharge. After a year the implementation of rehabilitation measures,compliance,condition and social improvement,relapse rate of hospitalization,accident rate and knowledge of family disease between the two groups of patients were compared and analyzed. Results The compliance and rehabilitation measures of the patients in the App group were higher than those in the non installation group. The rate of knowledge about mental illness was higher in family members,and the improvement of SCL-90 score and psychosocial function assessment score after intervention was better than that of non installation group. The rate of relapse hospitalization and cause trouble were lower. The differences above were statistically significant. Conclusion The guardian APP platform helps doctors and guardians to make the monitoring work of patients with severe mental disorder really practical,and the rehabilitation effect is better than the traditional rehabilitation method,which is worthy of further promotion and application.
论著
目的 本研究旨在采用连续气道监测法对患者呼吸力学指标进行动态观察,同时监测脑电双频指数(Bispectral index,BIS)和清醒镇静评分(The Observer's Assessment of Alertness/Sedation Scale,OAA/S),全面系统地评估右旋美托咪定(dexmedetomidine ,Dex)对患者自主呼吸功能和镇静深度的影响,为Dex临床安全应用提供参考依据。方法 80例患者随机分为四组,Dex 0.5 μg/kg组(D1组),1.0 μg/kg组(D2组),1.5 μg/kg组(D3组)和对照组(D0组),每组病人20例。麻醉诱导前35min分别静脉泵注Dex或0.9%生理盐水10 mL。记录预先给药前(T0 )、预处理后5min(T1)、10min(T2)、15min(T3)、20min(T4)、25min(T5)和30min(T6)患者的潮气量(VT)、分钟通气量(MV)、呼气末二氧化碳分压(PETCO2)、呼吸频率(RR)、第一秒呼出率(FEV1%)、顺应性环(PV环)、阻力环(FV环)、脉搏氧饱和度(SpO2)、心率(HR)、平均动脉压(MAP)等呼吸力学参数和循环参数及脑电双频谱指数(BIS)及警觉/镇静评分(OAA/S),并于T0、T1、T3和T6抽取动脉血行血气分析记录PaO2、PaCO2和pH值。结果 与对照组相比,D1组的VT、RR、MV、PETCO2、FEV1%、PaCO2和SpO2均无变化(P>0.05),PV环和FV环形态基本正常;D2组和D3组MV分别降低16.9%和27.0%;PaCO2分别升高11.0%和19.9%;FEV1%分别下降11.0%和14.9%。四组患者均无发生呼吸暂停,而且所有患者SpO2均在98%或以上。D3组自主呼吸的PV环和FV环图形面积明显缩小(P<0.05)。D1组BIS值均在85以上,OAA/S 4分为65%,镇静满意率低,OAA/S 3分仅20%;D2组镇静满意率最高,OAA/S 3分达70%,且无出现过度镇静;D3组有60%患者OAA/S评分小于或等于2。结论 静脉泵注Dex所产生的的镇静效应及其对呼吸力学的影响,随着泵注Dex剂量增大,患者镇静程度加深,虽然SpO2仍在正常范围,但呼吸会受到一定抑制(PV环和FV环图形面积缩小,PaCO2 均上升),临床推荐静脉泵注Dex剂量为0.5 μg/kg~1 μg/kg以策安全。
Objective The purpose of this study was to observe the dynamic indexes of respiratory mechanics in patients with continuous airway monitoring,and to monitor the Bispectral index (BIS) and the Observer's Assessment of Alertness/Sedation Scale (OAA/S). We evaluated the effect of dexmedetomidine (Dex) on the autonomic respiratory function and the sedative depth of the patients in a comprehensive and systematic way,so as to provide reference for the clinical safety of Dex. Methods In the study,we randomly divided 80 patients into four groups,Dex 0.5,group g/kg (group D1),1 group g/kg (group D2),1.5 g/kg group (D3 group) and control group (D0 group). There were 20 cases in each group. At about 35min before anesthesia induction,Dex or 0.9% saline 10 mL was injected intravenously. The following time points were selected: pre- administration (T0),pre-treated 5min (T1),pre-treated 10min (T2),pre-processed 15min (T3),pre-processed 20min (T4),pre -treated 25min (T5) and pre-treated 30min. The following experimental parameters were recorded at the above time point: tidal volume (VT),minute ventilation (MV),end expiratory carbon dioxide partial pressure (PETCO2),respiratory frequency (RR),first second exhalation rate (FEV1%),compliance ring (PV ring),resistance ring (FV ring),pulse oxygen saturation (SpO2),heart rate (HR),and respiratory mechanics parameters and circulatory parameters such as mean arterial pressure (MAP),bispectral index (BIS) and vigilance / sedation score (OAA/S). At the same time at T0,T1,T3 and T6,arterial blood gas was extracted,and PaO2,PaCO2 and pH values were recorded. Results Compared with the control group,the value of VT,RR,MV,PETCO2,FEV1%,PaCO2 and SpO2 in group D1 did not change significantly (P>0.05),and the morphology of PV ring and FV ring were basically normal. In group D2 and group D3,MV decreased by 16.9% and 27% respectively;PaCO2 increased by 11% and 19.9% respectively;FEV1% decreased by 11% and 14.9% respectively. No apnea occurred in the four groups,and all patients had SpO2 at 98% or above. The area of PV rings and FV rings of spontaneous breathing in group D3 was reduced (P<0.05). The BIS values in group D1 were above 85,OAA/S 4 was 65%,sedative satisfaction rate was low,20% patients had a score of 3 in OAA/S;group D2 had the highest sedative satisfaction rate,70% of patients had a score of 3 in OAA/S,and no excessive sedation;60% of patients in group D3 with an OAA/S score that was less than or equal to 2. Conclusion The sedation effect that was caused by intravenous infusion of Dex and its effect on respiratory mechanics are as follows: with the increase of Dex's dose,the degree of sedation is deepened. Although SpO2 is still in the normal range,the respiration will be restrained (the area of PV ring and FV ring is narrowed,the value of PaCO2 is increased),and the clinical recommendation of intravenous infusion Dex is at a dose of 0.5µg /kg~1µg /kg for safety reasons. .
论著
目的 探讨胆碱能受体激动剂尼古丁对子痫前期大鼠的治疗作用及机制。方法 将30只妊娠SD大鼠分为对照组(n =10)、子痫前期组(n =10)和尼古丁治疗组(n =10)。子痫前期组中,大鼠妊娠第14天注射内毒素(l.0 μg/kg);对照组给予等量生理盐水2 mL,研究组妊娠第14 天开始皮下注射尼古丁1 mg/(kg·d)至妊娠第19天。检测各组干预前后收缩压、24小时蛋白、妊娠结局和大鼠外周血IL-6,TNF-α,IFN-γ和IL-1β的表达水平。结果 和对照组相比,大鼠动脉收缩压妊娠第14天注射LPS后升高,治疗组中在尼古丁注射后,妊娠第16天、第18天较子痫前期组血压下降(14.99±0.48 vs 16.61±0.55 kPa,15.01±0.60 vs 17.04±0.49 kPa,P<0.05);大鼠24 h蛋白尿在子痫前期组中妊娠第17、19天升高(P<0.05),尼古丁治疗组尿蛋白较子痫前期组降低(P <0.05)。妊娠第20天,子痫前期组胎儿重量和对照组相比下降(P <0.05),尼古丁治疗组较子痫前期模型组胎儿重量增加(P <0.05)。各组间存活胎儿数、胎盘重量差异无统计学意义(P >0.05)。子痫前期组炎性因子IL-6,TNF-α,IFN-γ和IL-1β 较对照组升高,差异有统计学意义;尼古丁治疗组IL-6,TNF-α,IFN-γ 和IL-1β 降低(P <0.05)。结论 胆碱能受体激动剂尼古丁通过降低炎性反应来改善子痫前期大鼠的妊娠结局。
Objective To examine the effects and mechanism of cholinergic receptor agonist nicotine on preeclampsia rats. Methods 30 pregnant SD rats were divided into control group(n=10),preeclampsia group(n=10) and nicotine treatment group(n=10).In preeclampsia group,rats were injected LPS(l.0 μg/kg) on the day 14th of gestation,the control rats were injected 2 mL of physical saline on the day 14th of gestation,the rats in nicotine treatment group were injected nicotine 1mg/(kg·d) from the day 14th to the day 19th of gestation. The systolic blood pressure,24 hour urine protein,pregnancy outcome and serum levels of IL-6,TNF-α,IFN-γ and IL-1β were compared between each groups. Results Compared to control group,the systolic blood pressure rose after LPS injection on the day 14th of gestation,the systolic blood pressure in nicotine treatment group decreased on the day 16th and the day 18th of gestation compared to preeclampsia group(14.99±0.48 vs 16.61±0.55 kPa,15.01±0.60 vs 17.04±0.49 kPa,P<0.05).The 24 hour urine in preeclampsia group rose on day 17 and day 19 of gestation(P <0.05),which decreased in nicotine group(P <0.05). The fetal weight were higher in nicotine treatment group compared to the preeclampsia group,there were no statisitical difference in viable fetal number and placental weight among groups. The serum levels of IL-6,TNF-α,IFN-γ IL-1β were higher in preeclampsia group compared to the control group,while nicotine decreased the levels of IL-6,TNF-α,IFN-γ IL-1β(P <0.05). Conclusion Nicotine improved pregnancy outcome of LPS induced preeclampsia rats by decreasing inflammatory levels.
临床诊疗
目的 探讨妊娠期高血糖患者母体胰岛β细胞自身抗体对新生儿的影响。方法 选取2014年3月—2016年3月于我院就诊的口服75 g葡萄糖耐量试验(OGTT)异常的孕妇共276例,以60例健康孕妇作为对照组,分别在产前和OGTT试验后空腹抽取静脉血进行检测,检测指标包括谷氨酸脱羧酶抗体(GADA)、胰岛细胞抗体(ICA) )和胰岛素自身抗体(IAA),记录每个出生患儿的体重、Apgar评分、血糖指标进行分析。结果 276例GDM患者中34.41%至少存在一种相关抗体阳性,GDM组GADA阳性、IAA阳性和阴性的搏动指数异常比例均高于健康组(P<0.05),IAA阳性的胎儿生长受限比例比例较GDM组抗体阴性的比例高(P<0.05),妊娠晚期胰岛细胞抗体阳性(OR:6.41,95%CI:1.41~34.13)均为新生儿产后进入ICU进行监护的风险因素,妊娠中、晚期GADA阳性(OR:10.26,95%CI:1.42~75.14) 和妊娠晚期GADA阳性(OR:8.15,95%CI:1.43~46.83)均为新生儿窒息的风险因素 。结论 妊娠晚期胰岛细胞抗体阳性为新生儿产后进入ICU进行监护的风险因素,妊娠中、晚期GADA阳性是新生儿窒息的风险因素。
论著
目的 了解本地区住院疾病谱的特征,为疾病防治工作及合理配置医疗资源提供参考依据。方法 收集2014年佛山市主要二级以上医院的病案首页资料,根据ICD-10进行分类统计。结果 前五位疾病类型为:肿瘤、循环系统疾病、损伤和中毒、妊娠分娩和产褥期、消化系统疾病,与全国城市医院住院疾病谱不同。结论 佛山市的疾病控制重点有其特点,医院的发展和配置应围绕这些相关学科作为重点。
Objective To investigate the characteristics of the spectrum of diseases of inpatients in the region,which is aimed to provide reference for disease control and allocating medical resources reasonably. Methods Collecting the medical record front pages of inpatients of most secondary or above hospitals in Foshan city in 2014. The diseases identities of the included cases were counted according to ICD-10. Results The top five diseases spectrum were tumor, diseases of the circulatory system, injury, poisoning and certain other consequences of external causes, pregnancy, childbirth and the puerperium, diseases of the digestive system,which was different from that of the urban hospitals of the whole country. Conclusion There is a characteristic about the key emphasis in disease control in Foshan city. We should focus on these related subjects for the hospital development and configuration.
论著
目的 探讨 FAST-FIX全内缝合系统治疗膝关节半月板后角损伤的3年中期疗效。方法 2011年1月—2013年4月采用FAST-FIX全内缝合系统治疗膝关节半月板后角损伤并均得到满意随访的患者46例,其中男27例,女19例,年龄17~42 a,平均(23.5±8.22)a。左膝25例,右膝21例,损伤类型:红区损伤33例,红白区损伤13例,其中8例伴交叉韧带损伤。根据Barrett标准评价半月板愈合情况,并用Lysholm评分、IKDC评分、Tegner评分分别评估术后关节功能改善情况。术前Lysholm评分为:(35.73±11.28)分,IKDC评分为:(37.26±13.17)分,Tegner评分为(3.3±1.7)。结果 随访时间36~59个月,平均随访46.3个月,随访3年显示42例患者半月板愈合良好,手术成功率91.3%。术后4例患者出现疼痛,其中2例出现绞索,二次手术证实缝合失败并行半月板成形术。术后3年Lysholm评分为:(86.31±11.89)分,IKDC评分为:(82.9±13.44)分,Tegner评分为(5.9±1.9)。术前与术后3年随访评分相比均有统计学意义(P<0.05)。结论 FAST-FIX全内缝合系统治疗膝关节半月板后角损伤3年中期疗效良好。
Objective To evaluate a 3-year mid-term clinical results of FAST-FIX suture system in arthroscopic meniscal posterior horn repair. Methods Clinical results of 46 patients with meniscal tear who underwent posterior horn of the meniscus repair using the FAST-FIX suture system from January 2011 to April 2013 were retrospectively analyzed. There were 27 males and 19 females,age 17~42 years old,average 23.5±8.22 years old. There were 25 left knee and 21 right knee and 33 red zone injury and 13 red-white zone injury, 8 of which were accompanied by anterior cruciate ligament injury. Clinical healing of the meniscus was assessed by Lysholm scores(35.73±11.28)points,IKDC scores(37.26±13.17)points and Tegner scores(3.3±1.7)points before operation. Results The average follow-up period was 46.3 months (range: 36-59 months). The clinical healing rate was 91.3%. Healing failure occurred to 4 patients and 2 of which had a meniscus noose after operation and were confirmed surgical failure in reoperation. Mean Lysholm scores were (86.31±11.89),IKDC scores(82.9±13.44)and Tegner scores(5.9±1.9)in 3 years after operation for all 46 cases. The differences between the preoperative and postoperative scores in three type scores were statistically significant (P<0.05). Conclusion Arthroscopic posterior horn of the meniscus repair with the FAST-FIX suture system may provide good 3-year mid-term clinical results after operation.