冠状动脉血管成像联合动态心电图与冠心病冠脉狭窄程度及预后的关联研究

Study on the correlation between Coronary CT angiography combined with dynamic electrocardiogram and the degree and prognosis of coronary stenosis in coronary heart disease

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目的:分析冠状动脉CT血管成像(CTA)联合动态心电图(DCG)与冠心病患者冠脉狭窄程度及预后情况的关联。方法:研究对象选择我院2024年1月~2025年3月收治的210例冠心病患者及同期接受检查的210例非冠心病患者,分别列为病例组和对照组,比较两组CTA参数、DCG参数间差异。依据入院测得(Gensini)评分不同,将入组患者分别列为轻度组(60例,Gensini评分≤30分)、中度组(75例,Gensini评分>30分、≤60分)和重度组(75例,Gensini评分>60分),比较三组CTA参数、DCG参数间差异,分析CTA参数、DCG参数与Gensini评分的相关性。统计入组患者不良预后发生情况,比较不同预后患者CTA参数、DCG参数间差异,归纳冠心病患者预后影响因素,检验CTA参数、DCG参数对患者不良预后的预测效能。结果:病例组的最小管腔直径(MLD)、最小管腔面积(MLA)、血流储备分数(FFR)、正常窦性间期的标准差(SDNN)、每5min平均RR间期的标准差(SDANN)、相邻RR间期差值的均方根(RMSSD)均低于对照组,斑块总体积(TPV)、低频/高频比值(LF/HF)均高于对照组(t=24.128,25.811,15.613,37.636,26.858,9.195,59.862,29.389;P<0.05)。重度组的MLD、MLA、FFR、SDNN、SDANN、RMSSD均低于中度组,轻度组,TPV、LF-HF均高于中度组,轻度组(F=190.291,51.562,186.482,42.084,44.413,22.541,56.503,109.983;P<0.05)。MLD、MLA、FFR、SDNN、SDANN、RMSSD均与Gensini评分负相关,TPV、LF-HF均与Gensini评分正相关(r=-0.352,-0.377,-0.445,-0.472,-0.332,-0.356,0.401,0.355;P<0.05)。经统计,210例冠心病患者的不良预后发生率为38.10%(80/210)。预后不良组的MLD、MLA、FFR、SDNN、SDANN、RMSSD均低于预后良好组,TPV、LF-HF均高于预后良好组(t=6.827,12.219,19.313,6.097,7.097,5.027,7.088,12.465;P<0.05)。MLA、FFR、SDNN升高为冠心病不良预后的保护因素,LF/HF升高为冠心病不良预后的危险因素。FFR、SDNN联合检测预测不良预后的 AUC 值优于两项指标单独检测(Delong检验,P<0.05)。结论:CTA、DCG能客观评估冠心病患者冠脉狭窄程度,联合检测FFR、SDNN可作为预测冠心病不良预后的重要辅助手段。
Objective:To analyze the correlation between CTA combined with DCG and the degree of coronary stenosis and prognosis in patients with coronary heart disease.Methods:The research subjects selected were 210 patients with coronary heart disease admitted to our hospital from January 2024 to March 2025, as well as 210 non coronary heart disease patients who underwent examinations during the same period. They were divided into a case group and a control group. The differences in CTA parameters and DCG parameters between the two groups were compared. According to the different Gensini scores obtained upon admission, the enrolled patients were divided into mild group (60 cases, Gensini score ≤ 30 points), moderate group (75 cases, Gensini score>30 points, ≤ 60 points), and severe group (75 cases, Gensini score>60 points). The differences in CTA parameters and DCG parameters among the three groups were compared, and the correlation between CTA parameters, DCG parameters, and Gensini score was analyzed. Statistically analyze the occurrence of poor prognosis in enrolled patients, compare the differences in CTA and DCG parameters among patients with different prognoses, summarize the factors affecting the prognosis of coronary heart disease patients, and test the predictive power of CTA and DCG parameters for poor prognosis in patients.Results:The MLD, MLA, FFR, SDNN, SDANN, and RMSSD in the case group were all lower than the control group, while the TPV and LF/HF were higher than the control group (t=24.128,25.811,15.613,37.636,26.858,9.195,59.862,29.389; P<0.05). The MLD, MLA, FFR, SDNN, SDANN, and RMSSD of the severe group were lower than the moderate group, mild group, while the TPV and LF-HF of the mild group were higher than the moderate group, mild group (F=190.291,51.562,186.482,42.084,44.413,22.541,56.503,109.983; P<0.05). MLD, MLA, FFR, SDNN, SDANN, and RMSSD are all negatively correlated with Gensini score, while TPV and LF-HF are positively correlated with Gensini score (r=-0.352,-0.377,-0.445,-0.472,-0.332,-0.356,0.401,0.355; P<0.05). According to statistics, the incidence of poor prognosis in 210 patients with coronary heart disease was 38.10% (80/210). The MLD, MLA, FFR, SDNN, SDANN, and RMSSD of the poor prognosis group were lower than the good prognosis group, while TPV and LF-HF were higher than the good prognosis group (t=6.827,12.219,19.313,6.097,7.097,5.027,7.088,12.465; P<0.05). High MLA, FFR, and SDNN are protective factors for poor prognosis of coronary heart disease, while higher values than LF/HF are risk factors for poor prognosis of coronary heart disease. The combined detection of FFR and SDNN has a better AUC value for predicting poor prognosis of coronary heart disease than the detection of FFR and SDNN alone (Delong test, P<0.05).Conclusion:CTA and DCG can objectively evaluate the degree of coronary stenosis in patients with coronary heart disease, and combined detection of FFR and SDNN can be an important auxiliary tool for predicting poor prognosis of coronary heart disease.

器械护士术中分区精细化器械管理对心脏瓣膜置换术手术效率及安全性的影响研究

Study on the Impact of Refined Intraoperative Zone-Based Instrument Management by Scrub Nurses on the Efficiency and Safety of Cardiac Valve Replacement Surgery

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【摘要】目的:探讨器械护士术中分区精细化器械管理对心脏瓣膜置换术(HVR)手术效率及安全性的影响。方法:研究对象包括2024年6月~2026年5月至我院行HVR治疗的110例心脏瓣膜病(VHD)患者,以及同期参与手术的22名器械护士,采用随机数字表法将入组患者及护士分别列为常规组(55例患者、11名护士)、试验组(55例患者、11名护士),常规组内护士术中实施常规器械管理,试验组内护士术中实施分区精细化器械管理。比较两组患者的手术效率、围手术期安全事件,以及两组护士所参与手术的工作效率、术中器械管理情况。结果:在不同器械管理模式下,试验组内患者的主动脉阻断时间、体外循环时间、术中非必要等待时间、手术总耗时均低于常规组(t=8.817,5.730,20.609,9.632;P<0.05)。试验组内患者的围手术期安全事件发生率9.09%(5/55)低于常规组25.45%(14/55)(x2=5.153;P<0.05)。试验组内护士的器械摆台时间、器械传递反应时间、手术中断次数、器械整理时间、器械移交时间均低于常规组(t=3.347,6.505,5.971,3.795,5.838;P<0.05)。试验组内护士的器械管理差错率低于常规组(x2=5.238;P<0.05)。结论:器械护士术中分区精细化器械管理能提高HVR患者的手术效率并降低围手术期安全事件发生风险,对提高器械护士的器械管理质量、预防器械管理差错有积极影响
[Abstract]Objective:To explore the impact of refined intraoperative instrument management by operating room nurses on the efficiency and safety of HVR surgery.Methods:The study subjects included 110 patients with VHD who underwent HVR treatment at our hospital from June 2024 to May 2026, along with 22 instrument nurses who participated in the surgeries synchronously. Using the random number table method, the enrolled patients and nurses were divided into a control group (55 patients, 11 nurses) and an experimental group (55 patients, 11 nurses). Nurses in the conventional group implemented routine instrument management during surgery, while nurses in the experimental group implemented zoned and refined instrument management during surgery. The surgical efficiency, perioperative safety events of the two groups of patients, as well as the work efficiency and intraoperative instrument management of the surgeries participated by the nurses in the two groups were compared.Results:Under different instrument management modes, the aortic occlusion time, extracorporeal circulation time, intraoperative non-essential waiting time, and total surgical time of patients in the experimental group were all lower than the control group (t=8.817,5.730,20.609,9.632; P<0.05). The incidence of perioperative safety events in the experimental group was 9.09% (5/55) lower than that in the control group 25.45% (14/55) (x2=5.153; P<0.05). The instrument placement time, instrument delivery response time, number of surgical interruptions, instrument sorting time, and instrument handover time of nurses in the experimental group were lower than those in the control group (t=3.347,6.505,5.971,3.795,5.838; P<0.05). The error rate of nurses in the experimental group was lower than the control group (x2=5.238; P < 0.05).Conclusion:Refined intraoperative zone-specific instrument management by instrument nurses enhances surgical efficiency for HVR patients and reduces the risk of perioperative safety incidents, thereby positively impacting the quality of instrument care provided by nurses and preventing instrument-related adverse events.

改良拔尿管方法在妇科腹腔镜术后患者临床应用研究

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探讨改良拔尿管方法在妇科腹腔镜术后留置尿管患者临床的影响。方法 选取2025年2月7日—2025年10 月10日我院妇科腹腔镜手术术后留置尿管患者60例为研究对象。本研究采用随机数字表法将研究对象分为对照组与观察组,两组各纳入30例。比较两组首次拔管尿路疼痛评价、首次排尿时间、患者尿潴留例数。结果 观察组首次拔尿管尿路疼痛程度显著低于对照组,两组差异有统计学意义(P<0.05)。观察组首次排尿时间显著少于对照组,两组差异有统计学意义(P<0.05)。观察两组尿潴留发生率差异无统计学意义(P>0.05)。结论 本次研究采用改良后的尿管拔除方法,虽未明显降低妇科腹腔镜术后患者的尿潴留发生率,但能有效降低拔尿管时患者的不适感 ,减少尿道损伤,缓解疼痛,加快患者自主排尿,具有积极临床实践意义

惯性测量步态分析研究热点及护理转化前景

Research Hotspots and Nursing Translation Prospects of Inertial Measurement-Based Gait Analysis

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目的:基于文献计量学梳理惯性测量技术在步态分析领域的研究演进与热点结构,并从护理评估与干预转化角度分析其应用空白。方法:检索 Web of Science 核心合集2005年1月1日至2025年4月5日相关英文文献,纳入1,079篇记录;采用 CiteSpace 6.3.R1、VOSviewer 1.6.20 分析年度发文、国家/地区合作、期刊分布、关键词共现与突现,并在 Python 3.10 中以 PPMI/TF-IDF 表征、SVD降维、UMAP-HDBSCAN聚类开展关键词和摘要语义分析。结果:2006—2024年发文量由1篇增至140篇,年复合增长率为31.6%,2024年达到峰值;最高频关键词为 gait(404次)、gait analysis(268次)、walking(252次)、balance(183次)和 inertial sensors(156次)。关键词与摘要语义聚类的二维轮廓系数分别为0.579和0.642,热点集中于帕金森病/冻结步态、跌倒风险、平衡稳定性、可穿戴传感器、机器学习和康复干预。含 nursing/care 等护理相关词项的记录为142篇,但“护理”尚未形成独立主题簇。结论:惯性测量步态分析已形成医工交叉的成熟热点,但护理主导的连续评估、风险预警和干预闭环仍不足。未来应将步速、步态变异性、稳定性、对称性等参数转化为可执行的护理评估指标,推动精准护理场景中的临床验证与流程整合。
Objective: To map the research evolution and hotspot structure of inertial-measurement-based gait analysis and to examine its translational gap in nursing assessment and intervention. Methods: A total of 1,079 English records published from January 1, 2005 to April 5, 2025 were retrieved from the Web of Science Core Collection. CiteSpace 6.3.R1 and VOSviewer 1.6.20 were used for annual output, collaboration, journal distribution, keyword co-occurrence and burst analyses. Keyword and abstract semantic clusters were further examined in Python 3.10 using PPMI/TF-IDF representation, SVD, UMAP and HDBSCAN. Results: Publications increased from 1 in 2006 to 140 in 2024, with a compound annual growth rate of 31.6%. The most frequent terms were gait, gait analysis, walking, balance and inertial sensors. The two-dimensional silhouette coefficients of keyword and abstract semantic clusters were 0.579 and 0.642, respectively. Major hotspots involved Parkinson disease/freezing of gait, fall risk, balance and stability, wearable sensors, machine learning and rehabilitation. Records containing nursing/care-related terms accounted for 142 publications, but nursing did not form an independent topic cluster. Conclusion: Inertial-measurement-based gait analysis has become a mature medical-engineering research field, while nurse-led continuous assessment, risk warning and intervention feedback loops remain underdeveloped. Translating gait speed, variability, stability and symmetry into actionable nursing indicators should be prioritized in future clinical validation.

惯性测量步态分析研究热点及护理转化前景

Research Hotspots and Nursing Translation Prospects of Inertial Measurement-Based Gait Analysis

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目的:基于文献计量学梳理惯性测量技术在步态分析领域的研究演进与热点结构,并从护理评估与干预转化角度分析其应用空白。方法:检索 Web of Science 核心合集2005年1月1日至2025年4月5日相关英文文献,纳入1,079篇记录;采用 CiteSpace 6.3.R1、VOSviewer 1.6.20 分析年度发文、国家/地区合作、期刊分布、关键词共现与突现,并在 Python 3.10 中以 PPMI/TF-IDF 表征、SVD降维、UMAP-HDBSCAN聚类开展关键词和摘要语义分析。结果:2006—2024年发文量由1篇增至140篇,年复合增长率为31.6%,2024年达到峰值;最高频关键词为 gait(404次)、gait analysis(268次)、walking(252次)、balance(183次)和 inertial sensors(156次)。关键词与摘要语义聚类的二维轮廓系数分别为0.579和0.642,热点集中于帕金森病/冻结步态、跌倒风险、平衡稳定性、可穿戴传感器、机器学习和康复干预。含 nursing/care 等护理相关词项的记录为142篇,但“护理”尚未形成独立主题簇。结论:惯性测量步态分析已形成医工交叉的成熟热点,但护理主导的连续评估、风险预警和干预闭环仍不足。未来应将步速、步态变异性、稳定性、对称性等参数转化为可执行的护理评估指标,推动精准护理场景中的临床验证与流程整合。
Objective: To map the research evolution and hotspot structure of inertial-measurement-based gait analysis and to examine its translational gap in nursing assessment and intervention. Methods: A total of 1,079 English records published from January 1, 2005 to April 5, 2025 were retrieved from the Web of Science Core Collection. CiteSpace 6.3.R1 and VOSviewer 1.6.20 were used for annual output, collaboration, journal distribution, keyword co-occurrence and burst analyses. Keyword and abstract semantic clusters were further examined in Python 3.10 using PPMI/TF-IDF representation, SVD, UMAP and HDBSCAN. Results: Publications increased from 1 in 2006 to 140 in 2024, with a compound annual growth rate of 31.6%. The most frequent terms were gait, gait analysis, walking, balance and inertial sensors. The two-dimensional silhouette coefficients of keyword and abstract semantic clusters were 0.579 and 0.642, respectively. Major hotspots involved Parkinson disease/freezing of gait, fall risk, balance and stability, wearable sensors, machine learning and rehabilitation. Records containing nursing/care-related terms accounted for 142 publications, but nursing did not form an independent topic cluster. Conclusion: Inertial-measurement-based gait analysis has become a mature medical-engineering research field, while nurse-led continuous assessment, risk warning and intervention feedback loops remain underdeveloped. Translating gait speed, variability, stability and symmetry into actionable nursing indicators should be prioritized in future clinical validation.

基于超声实时引导的精准骶管阻滞联合喉罩全麻对阴式子宫切除手术患者术中应激与术后肠功能恢复的作用研究

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目的:探讨基于超声实时引导的精准骶管阻滞联合喉罩全麻对阴式子宫切除手术患者术中应激反应及术后肠功能恢复的影响。方法:本研究采用前瞻性、单中心随机对照试验,选取2023年1月至2025年1月于我院择期行阴式子宫切除术的患者108例,随机分为对照组(n=54)和观察组(n=54)。对照组行单纯喉罩全身麻醉,观察组行超声实时引导精准骶管阻滞(0.25%罗哌卡因20 mL)联合喉罩全身麻醉。比较两组患者术中不同时间点血流动力学指标[平均动脉压(MAP)、心率(HR)]、应激反应指标[血清皮质醇(COR)、去甲肾上腺素(NE)、血糖(GLU)]、术后肠功能恢复指标(肠鸣音恢复时间、首次排便时间、首次排气时间)、术后疼痛视觉模拟评分(VAS)、术后镇痛泵有效按压次数、补救镇痛率及不良反应发生率。主要结局指标为术后24 h VAS评分,次要结局指标包括术中应激反应指标和术后肠功能恢复指标。结果:两组患者年龄、BMI、手术时间及术中出血量比较,差异均无统计学意义(P>0.05)。与T0时点比较,两组T1、T2、T3时点MAP、HR均升高,但观察组T1、T2、T3时点MAP、HR均低于对照组(P<0.05)。两组T1、T2、T3时点COR、NE、GLU水平均高于T0时点,但观察组T1、T2、T3时点COR、NE、GLU水平均低于对照组(P<0.05)。观察组术后肠鸣音恢复时间、首次排便时间及首次排气时间均短于对照组(P<0.05)。观察组术后2 h、6 h、12 h、24 h VAS评分均低于对照组(P<0.05),术后镇痛泵有效按压次数及补救镇痛率均低于对照组(P<0.05)。观察组术后恶心呕吐(PONV)发生率低于对照组(P<0.05),两组尿潴留发生率比较差异无统计学意义(P>0.05)。结论:基于超声实时引导的精准骶管阻滞联合喉罩全麻可有效减轻阴式子宫切除手术患者术中应激反应,维持血流动力学稳定,促进术后肠功能恢复,提高术后镇痛质量,且不增加不良反应发生率,值得临床推广应用。
Objective: To investigate the effects of ultrasoundguided realtime precise caudal block combined with laryngeal mask airway (LMA) general anesthesia on intraoperative stress response and postoperative bowel function recovery in patients undergoing vaginal hysterectomy. Methods: This prospective, singlecenter randomized controlled trial enrolled 108 patients who underwent elective vaginal hysterectomy in our hospital from January 2023 to January 2025. They were randomly divided into a control group (n=54) and an observation group (n=54). The control group received LMA general anesthesia alone, while the observation group received ultrasoundguided realtime precise caudal block (0.25% ropivacaine 20 mL) combined with LMA general anesthesia. The following parameters were compared between the two groups: hemodynamic variables [mean arterial pressure (MAP), heart rate (HR)] at different intraoperative time points, stress response indicators [serum cortisol (COR), norepinephrine (NE), blood glucose (GLU)], postoperative bowel function recovery indicators (time to bowel sound recovery, time to first defecation, time to first flatus), postoperative pain Visual Analog Scale (VAS) scores, effective pressing times of patientcontrolled analgesia (PCA) pump, rescue analgesia rate, and incidence of adverse reactions. The primary outcome was the 24 h postoperative VAS score; secondary outcomes included intraoperative stress response indicators and postoperative bowel function recovery indicators. Results: No significant differences were found between the two groups in age, BMI, operative time, or intraoperative blood loss (P>0.05). Compared with T0, MAP and HR at T1, T2 and T3 were increased in both groups, but the MAP and HR at T1, T2 and T3 in the observation group were significantly lower than those in the control group (P<0.05). Levels of COR, NE and GLU at T1, T2 and T3 were higher than those at T0 in both groups, but the levels in the observation group were significantly lower than those in the control group at the corresponding time points (P<0.05). The time to bowel sound recovery, time to first defecation and time to first flatus in the observation group were significantly shorter than those in the control group (P<0.05). The VAS scores at 2 h, 6 h, 12 h and 24 h postoperatively in the observation group were significantly lower than those in the control group (P<0.05); the effective pressing times of PCA pump and the rescue analgesia rate in the observation group were also significantly lower than those in the control group (P<0.05). The incidence of postoperative nausea and vomiting (PONV) in the observation group was significantly lower than that in the control group (P<0.05), whereas no significant difference was observed in the incidence of urinary retention between the two groups (P>0.05). Conclusion: Ultrasoundguided realtime precise caudal block combined with LMA general anesthesia can effectively alleviate intraoperative stress response, maintain hemodynamic stability, promote postoperative bowel function recovery, and improve postoperative analgesia quality in patients undergoing vaginal hysterectomy, without increasing the incidence of adverse reactions. Therefore, this combined anesthesia technique is worthy of clinical application.

超声骨刀与高速涡轮手机在颌骨囊肿外科手术中的应用效果及安全性研究

Research on the Application Effect and Safety of Ultrasonic Bone Knife and High speed Turbine Mobile Phone in Jaw Cyst Surgery

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【摘要】目的:探讨超声骨刀与高速涡轮手机在颌骨囊肿患者外科手术中的应用效果及安全性。方法:研究选择2024年1月~2025年6月至我院行囊肿刮治术治疗的100例颌骨囊肿患者,通过隐藏信封法将入组患者随机列为常规组、试验组,每组50例。常规组术中应用高速涡轮手机去骨,试验组术中应用超声骨刀去骨,比较两组患者的手术情况,术后疼痛肿胀情况及住院期间并发症发生情况。术毕随访半年,比较两组患者神经损伤情况及骨愈合情况。结果:试验组的术中出血量、术后24h引流量、切骨精度偏差分别为(30.59±5.24)mL、(20.55±5.28)mL、(0.18±0.05)mm,均低于常规组[(40.19±7.33)mL、(30.46±6.45)mL、(0.59±0.12)mm](t=7.534,8.407,22.301;P<0.05);手术耗时与常规组比较,差异无统计学意义(P>0.05)。试验组术后24h、48h、72h的视觉模拟疼痛量表(VAS)评分,肿胀评分均低于常规组(t=4.403,3.354,12.986,4.610,2.911,14.888;P<0.05)。试验组住院期间的并发症发生率4.00%(2/50)低于常规组18.00%(9/50)(x2=5.005;P<0.05)。试验组随访第1个月、第3个月、第6个月的神经传导速度(NCV)均高于常规组,两点辨别觉(TPD)均低于常规组(t=4.598,5.784,6.322,3.194,3.595,3.501;P<0.05)。截至随访结束时,试验组的成骨率分别为(75.27±8.14)%高于常规组(68.18±5.27)%],骨缺损面积、创面愈合时间、骨吸收量分别为(55.29±5.42)%、(3.22±0.47)月、(1.25±0.36)mm,均低于常规组[(62.44±7.51)%、(5.08±1.33)月、(2.49±0.32)mm](t=5.170,5.459,9.324,18.204;P<0.05)。结论:与高速涡轮手机相比,超声骨刀可降低颌骨囊肿患者术中出血风险并实现精准去骨,在减轻术后疼痛、肿胀程度同时能一定程度减轻术后神经损伤,对促进患者骨愈合也有积极影响。
[Abstract]Objective:To explore the application effect and safety of ultrasound bone scalpel and high-speed turbine mobile phone in surgical procedures for patients with jaw cysts.Methods:A total of 100 patients with maxillary cysts who underwent curettage surgery in our hospital from January 2024 to June 2025 were selected for the study. The enrolled patients were randomly divided into a control group and an experimental group using the hidden envelope method, with 50 patients in each group. The conventional group used high-speed turbine mobile phones for bone removal during surgery, while the experimental group used ultrasonic bone knives for bone removal during surgery. The surgical conditions, postoperative pain and swelling, and incidence of complications during hospitalization were compared between the two groups of patients. Follow up for six months after surgery to compare the nerve damage and bone healing between the two groups of patients.Results:The intraoperative bleeding volume, postoperative 24-hour drainage volume, and bone cutting accuracy deviation of the experimental group were (30.59 ± 5.24) mL, (20.55 ± 5.28) mL, and (0.18 ± 0.05) mm, respectively, all lower than those of the control group [(40.19 ± 7.33) mL, (30.46 ± 6.45) mL, and (0.59 ± 0.12) mm] (t=7.534,8.407,22.301; P<0.05); The surgical time of the experimental group was similar to the control group (P>0.05). The VAS scores and swelling scores of the experimental group at 24, 48, and 72 hours after surgery were lower than the control group (t=4.403,3.354,12.986,4.610,2.911,14.888;; P<0.05). The incidence of complications during hospitalization in the experimental group was 4.00% (2/50) lower than the control group 18.00% (9/50) (x2=5.005; P<0.05).The NCV of the experimental group was higher than the control group at the1,3,6 months of follow-up, and TPD was lower than the control group (t=4.598,5.784,6.322,3.194,3.595,3.501; P<0.05). As of the end of follow-up, the osteogenic rate of the experimental group was (75.27 ± 8.14)% higher than the control group (68.18 ± 5.27)%. The bone defect area, wound healing time, and bone resorption were (55.29 ± 5.42)%, (3.22 ± 0.47) months, and (1.25 ± 0.36) mm, lower than the control group [(62.44 ± 7.51)%, (5.08 ± 1.33) months, and (2.49 ± 0.32) mm] (t=5.170,5.459,9.324,18.204; P<0.05).Conclusion:Compared with high-speed turbo phones, ultrasonic bone scalpel can reduce the risk of intraoperative bleeding in patients with jaw cysts and achieve precise bone removal. It can alleviate postoperative pain and swelling while greatly avoiding postoperative nerve damage, and has a positive impact on promoting bone healing in patients.

腰舒汤联合针灸推拿治疗气滞血瘀型腰椎间盘突出的临床研究

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目的 观察腰舒汤联合针灸推拿治疗气滞血瘀型腰椎间盘突出(LDH)的临床效果。方法 选取2023年1月~2025年12月收治的气滞血瘀型LDH患者104例,采用计算机随机分为参考组(52例采用针灸推拿治疗,因擅自使用方案外的药物剔除1例,)和综合组(52例采用腰舒汤联合针灸推拿治疗,因主动退出脱落1例)。比较两组中医证候评分、疼痛视觉模拟(VAS)评分、核因子-κB(NF-κB)信号通路指标、日本矫形外科学会(JOA)评分、腰背肌生物力学性能、脊旁肌横截面积(CSA)以及不良反应/事件发生率。结果 两组基线时中医证候评分、VAS评分、NF-κB信号通路指标、JOA评分比较差异不显著(P>0.05);两组治疗后JOA评分均较基线时升高,同时综合组高于对应时间参考组(P<0.05);两组治疗后中医证候评分、NF-κB信号通路指标、VAS评分均较基线时降低,同时综合组低于对应时间参考组(P<0.05)。两组基线时60°/s角速腰背肌生物力学性能比较差异不显著(P>0.05);两组治疗后W、PT均较基线时升高,同时综合组高于对应时间参考组(P<0.05);两组治疗后F/E均较基线时降低,同时综合组低于对应时间参考组(P<0.05)。两组基线时脊旁肌CSA比较差异不显著(P>0.05);两组治疗后L3、L4、L5的Sm/Sv均较基线时降低,同时综合组低于对应时间参考组(P<0.05);两组治疗后L3、L4的Se/Sv较基线时升高,同时综合组高于对应时间参考组(P<0.05);两组治疗后L5的Se/Sv以及L3、L4、L5的Sp/Sv与基线时比较差异不显著(P>0.05)。两组不良反应/事件发生率比较,差异不显著(P>0.05)。结论 腰舒汤联合针灸推拿治疗气滞血瘀型腰椎间盘突出可缓解症状、抑制炎症、改善腰背肌功能与形态,且安全性相当。

生化汤治疗药物流产后并发症的研究进展

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药物流产是终止早期妊娠的常用方法,但流产后仍易出现阴道持续出血、不全流产、盆腔感染及月经紊乱等并发症,影响患者生殖健康。生化汤作为中医经典方剂,具有活血化瘀、温经止痛、祛瘀生新之功效,在药物流产后并发症的临床治疗中应用广泛。本文通过梳理近年相关文献,从生化汤概述、药物流产及其并发症、生化汤的临床应用、作用机制及使用禁忌等方面进行系统综述,重点分析现有研究的局限性及争议性问题,并对未来研究方向提出展望,以为临床应用生化汤治疗药物流产后并发症提供理论依据与实践参考。?

推拿治疗巨大/破裂型腰椎间盘突出症的研究进展

Research progress on tuina for giant/ruptured lumbar disc herniation

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巨大/破裂型腰椎间盘突出症(G/RLDH)是腰椎间盘突出症的严重类型,可致剧烈根性疼痛及神经功能障碍。推拿作为非药物中医疗法,广泛应用于腰椎间盘突出症,但治疗G/RLDH的疗效与安全性尚存争议。近年发现G/RLDH具有较高的椎间盘自然重吸收率,为推拿干预提供了病理基础。本文系统检索相关文献,从中医病机、现代医学机制、临床应用及安全性争议等方面进行综述,旨在指导临床诊治并为未来研究提供参考。
Giant/ruptured lumbar disc herniation (G/RLDH) is a severe type of lumbar disc herniation that can cause intense radicular pain and neurological dysfunction. As a non-pharmacological therapy in traditional Chinese medicine, tuina is widely used for lumbar disc herniation; however, its efficacy and safety in treating G/RLDH remain controversial. Recent studies have revealed a relatively high rate of spontaneous resorption of herniated discs in G/RLDH, which provides a pathological basis for tuina intervention. This article systematically reviews the relevant literature, summarizing the traditional Chinese medicine pathogenesis, modern medical mechanisms, clinical application, and safety controversies, aiming to guide clinical diagnosis and treatment and to provide a reference for future research.
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