各位作者、审稿专家:
本刊官方微信服务号新增稿件状态查询服务,无需反复登录投稿系统,微信即可随时查看审稿进度、修回通知、录用结果,稿件更新实时推送提醒,同步接收期刊征稿、学术资讯。
微信搜索关注广州医药杂志服务号 → 点击菜单栏「绑定账号」→ 输入投稿邮箱完成账号关联;请关闭微信消息免打扰,避免遗漏稿件通知。
《广州医药》编辑部
目的 为寻找治疗盆腔炎性疾病(PID)的有效治疗方案,对比分析头孢哌酮舒巴坦钠+吗啉硝唑、康妇炎胶囊联合头孢哌酮舒巴坦钠及吗啉硝唑两种用药方案治疗PID的效果差异,期望为今后临床中合理选择PID药物治疗方案提供参考依据。方法 选取2019年1月—12月期间在我院接受治疗的104例急性PID患者(湿毒壅盛证)作为研究对象,用随机信封分为参照组、研究组,各52例。予以参照组患者头孢哌酮舒巴坦钠+吗啉硝唑静脉滴注治疗,研究组患者在参照组基础上口服康妇炎胶囊,均持续治疗14 d。观察2组患者近期疗效、炎性因子、盆腔炎性疾病包块、远期复发率(6个月、1年)、远期生活质量,综合评价两种用药方案应用效果。结果 治疗14 d后,研究组总有效率96.00%,高于参照组的80.39%,差异显著(P<0.05);WBC、CRP、IL-2、TNF-α四项炎性因子水平均低于参照组,差异显著(P<0.05);腔包块直径、疼痛评分均低于参照组,差异显著(P<0.05)。随访6个月、1年,研究组患者PID复发率分别为4.00%、10.00%,均低于参照组的15.69%、29.41%,差异显著(P<0.05)。结论 以康妇炎胶囊联合头孢哌酮舒巴坦钠及吗啉硝唑治疗PID,能够提升患者的近期治疗效果,改善炎性反应、盆腔炎性疾病包块,降低远期复发风险,改善远期生活质量,而且能够保证用药安全性,具有推广使用价值。
Objective To find an effective treatment for pelvic inflammatory disease(PID),and to compare and analyze the difference of efficacy of cefoperazone and sulbactam sodium + molinidazole,Kangfuyan capsule combined with cefoperazone and sulbactam sodium + molinidazole in the treatment of PID,in order to provide reference for rational selection of PID drug treatment in future clinical practice.Methods A total of 104 patients with acute PID(excessive wet toxin accumulation syndrome)who received treatment in our hospital from January to December 2019 were selected as the research objects.They were randomly divided into the control group and the research group with 52 cases in each group.Patients in the control group were given intravenous infusion of cefoperazone and sulbactam sodium + morinidazole,and patients in the research group were given Kangfuyan capsule orally on the basis of the control group,all treated for 14 days.The short-term efficacy,inflammatory factors,pelvic inflammatory mass and pain improvement,adverse reactions,long-term recurrence rate(6 months,1 year),long-term quality of life in two groups were observed,and the application effect of the two drug regimens was comprehensively evaluated.Results After 14 days of treatment,the total effective rate of the research group was 96.00%,which was higher than that of the control group(80.39%),with significant difference(P<0.05).After treatment,the levels of WBC,CRP,IL-2 and TNF-α were lower than those of the control group,and the differences were significant(P<0.05).After treatment,lumen mass diameter and pain score were lower than the control group,the differences were significant(P<0.05).After 6 months and 1 year follow-up,the PID recurrence rate of the research group was 4.00% and 10.00% respectively,both lower than that of the control group(15.69% and 29.41%),with significant difference(P<0.05).Conclusions Using Kangfuyan capsule combined with cefoperazone and sulbactam sodium + molinidazole in the treatment of PID,can improve the patient's recent treatment effect,improve the inflammatory reaction,pelvic inflammation mass, lower long-term risk of recurrence,improve the long-term quality of life,and can ensure medication safety,with promotion value.
目的 探讨消肿化瘀膏治疗骨性关节炎的临床疗效。方法 选择2017年5月—2022年1月在本院诊治的骨性关节炎患者124例作为研究对象,根据简单分配原则把患者分为消肿化瘀膏组与传统药物组各62例。传统药物组给予传统药物治疗,消肿化瘀膏组给予消肿化瘀膏治疗,判定2组患者治疗总显效率、疼痛评分、关节评分、血清中炎症因子水平变化。结果 消肿化瘀膏组治疗后的总显效率为98.4%,高于传统药物组的83.9%(P<0.05)。治疗后,2组的疼痛评分都低于治疗前(P<0.05),且消肿化瘀膏组低于传统药物组(P<0.05)。2组治疗后的关节评分都高于治疗前(P<0.05),且消肿化瘀膏组与传统药物组相比升高(P<0.05)。2组治疗后的血清白介素-1β、白介素-6水平都低于治疗前(P<0.05),且消肿化瘀膏组较传统药物组降低更多(P<0.05)。结论 消肿化瘀膏治疗骨性关节炎能有效抑制血清炎症因子的表达,缓解疼痛,改善关节功能,提高患者的总体治疗效果。
Objective To explore the clinical efficacy of Xiaozhonghuayu ointment in the treatment of osteoarthritis.Methods From May 2017 to January 2022,124 patients with osteoarthritis who diagnosed and treated in our hospital were selected as the research subjects.According to the simple allocation principle,the patients were divided into the Xiaozhonghuayu ointment group and the traditional medicine group with 62 cases each.The traditional medicine group was treated with traditional medicine,and the Xiaozhonghuayu ointment group was treated with Xiaozhonghuayu ointment.The total therapeutic efficiency,pain score,joint score,and the changes of serum inflammatory factors were compared in the two groups.Results The total efficiency of Xiaozhonghuayu ointment group after treatment were 98.4%,which were higher than 83.9% in the traditional medicine group(P<0.05).The pain scores in both groups after treatment were lower than those before treatment(P<0.05),and that in the Xiaozhonghuayu ointment group were lower than the traditional medicine group(P<0.05).The joint scores of the two groups after treatment were higher than those before treatment(P<0.05),and that in the Xiaozhonghuayu ointment group were higher than the traditional medicine group(P<0.05).After treatment,the levels of serum interleukin-1β and interleukin-6 in the two groups were significantly lower than those before treatment(P<0.05),compared with the traditional medicine group,those levels in the Xiaozhonghuayu ointment group also decreased significantly after treatment(P<0.05).Conclusions Xiaozhonghuayu ointment in the treatment of osteoarthritis can effectively inhibit the expressions of serum inflammatory factors,promote pain relief,improve joint function,and improve the overall therapeutic effect of patients.
目的 探讨乙酰半胱氨酸泡腾片联合布地格福气雾剂治疗慢性阻塞性肺疾病疗效及对患者肺功能的影响。方法 以2020年4月—2022月4月在本院诊治的84例慢性阻塞性肺疾病患者作为研究对象,根据1∶1简单分配原则把患者分为联合组与对照组各42例。对照组行传统治疗,联合组在对照组治疗的基础上,再给予乙酰半胱氨酸泡腾片联合布地格福气雾剂治疗,联合组与对照组都治疗观察4周。检测患者的疗效、肺功能与血清超敏C反应蛋白(hs-CRP)与降钙素原(PCT)含量变化情况。结果 联合组治疗后的总有效率与对照组相比有提高(P<0.05)。治疗后,联合组与对照组的第一秒用力呼气容积占用力肺活量百分比(FEV1/FVC)、第一秒用力呼气容积占预计值百分比(FEV1%)更高(P<0.05),且联合组与对照组对比有提高(P<0.05)。联合组治疗后的疾病影响、活动能力、症状部分等SGRQ生活质量评分与对照组相比降低(P<0.05)。联合组与对照组治疗后的血清 hs-CRP与 PCT含量低于治疗前(P<0.05),联合组与对照组相比也降低(P<0.05)。结论 乙酰半胱氨酸泡腾片联合布地格福气雾剂治疗慢性阻塞性肺疾病能有效抑制hs-CRP、PCT的表达,能促进改善患者的肺功能,提高治疗效果与生活质量。
Objective To investigate the efficacy of acetylcysteine effervescent tablets combined with budigraf aerosol in the treatment of chronic obstructive pulmonary disease(COPD)and its effect on the pulmonary function of patients.Methods From April 2020 to April 2022,a total of 84 patients with COPD diagnosed and treated in our hospital were selected as the research objects,and the patients were divided into the combination group and the control group with 42 cases in each group,according to the 1∶1 simple allocation principle.The control group were given traditional treatment,and the combination group were given acetylcysteine effervescent tablets combined with budigraf aerosol additionally.Both the combined group and the control group were observed for 4 weeks.The efficacy of patients,lung function and serum hypersensitive C-reactive protein(hs-CRP)and procalcitonin(PCT)levels were detected.Results The total effective rates after treatment in the combination group were higher than the control group(P<0.05).After treatment,The forced expiratory volume in 1 second/forced vital capacity(FEV1/FVC),FEV1% value of the two groups were higher(P<0.05),and the combination group had greater improvement(P<0.05).The SGRQ quality of life scores,such as disease impact,activity ability,and symptom in the combination group were lower(P<0.05).After treatment,the serum high-sensitivity C-reactive protein(hs-CRP)and procalcitonin(PCT)levels in the two groups were significantly lower(P<0.05),and the combined group decreased more(P<0.05).Conclusions Acetylcysteine effervescent tablets combined with budigraf aerosol in the treatment of COPD can effectively inhibit the expression of hs-CRP,PCT,promote the improvement of lung function,improve the treatment effect and quality of life.
目的 评价银杏二萜内酯葡胺注射液(DGMI)联合依达拉奉右崁对急性缺血性脑卒中(AIS)的治疗效果。方法 回顾性分析我院2021年3月—2022年6月收治的86例AIS患者,根据治疗方法不同,分为单药组和联合组,每组43例,2组均予以DGMI治疗,联合组加用依达拉奉右崁醇。对比2组的治疗效果。结果 治疗后,联合组美国国立卫生研究院卒中量表(NIHSS)评分低于单药组(P<0.05),简易智能精神状态检查量表(MMSE)和Barthel指数(BI)得分高于单药组(P<0.05);联合组治疗后脑血流动力学指标(Qmin和Vmin)高于单药组(P<0.05),而全血还原黏度、血浆黏度和血小板聚集指数低于单药组(P<0.05);联合组治疗后血清丙二醛(MDA)、超敏C-反应蛋白(hsCRP)和白细胞介素-6(IL-6)低于单药组(P<0.05),而超氧化物歧化酶(SOD)高于单药组(P<0.05);联合组治疗总有效率88.37%,高于单药组的67.44%(P<0.05),且2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论 DGMI联合依达拉奉右崁醇可有效提高AIS患者的神经功能、认知功能及日常生活能力,降低血液高凝状态,改善脑部血流,缓解机体氧化应激及炎症反应,且不良反应发生率较低,安全性良好。
Objective To evaluate the clinical efficacy of diterpene ginkgolides meglumine injection(DGMI)combined with edaravone dextracanthol in the treatment of acute ischemic stroke(AIS).Methods A total of 86 patients with AIS admitted to our hospital from March 2021 to June 2022 were divided into single drug group and combination group according to different treatment methods,with 43 patients in each group.Both groups were treated with DGMI,and the combination group was added with edaravone dextracanthol.The therapeutic effect,neurological function and adverse reactions of the two groups were compared.Results After treatment,compared with the single drug group,the NIH Stroke Scale(NIHSS)score of the combination group was significantly lower(P<0.05),and the Mini-Mental State Examination(MMSE)and Barthel index(BI)scores were significantly higher(P<0.05).After treatment,the cerebral hemodynamic indexes(Qmin and Vmin)in the combination group were significantly higher(P<0.05),while the whole blood reducing viscosity,plasma viscosity and platelet aggregation index were significantly lower(P<0.05).After treatment,compared with the single drug group,the serum malondialdehyde(MDA),high sensitive C-reactive protein(hsCRP)and interleukin- 6(IL-6)levels in the combination group were significantly lower(P<0.05),while the level of superoxide dismutase(SOD)was significantly higher(P<0.05).The total effective rate of the combination group was 88.37%,which was significantly higher than 67.44% of the single drug group(P<0.05).The incidence of adverse reaction between two groups was not significant(P>0.05).Conclusions DGMI combined with edaravone dextracanthol can effectively improve the neurological function,cognitive function and daily living ability of patients with AIS,reduce blood hypercoagulability,improve cerebral blood flow,alleviate oxidative stress and inflammatory reaction,improve the therapeutic effect,without increasing the incidence of adverse reactions,which has good safety.
目的 探讨影响宫腔修复的因素,为不全流产妇女选择期待治疗提供理论依据。方法 2021年1月—12月在香港大学深圳医院招募早孕药流不全的患者534例,记录其人口学特征以及从排胎到流产后3周到月经复潮后的相关情况,通过多因素Logistic回归分析影响不全流产者宫腔修复的因素。结果 534例药流不全患者中,月经复潮后宫腔残留240例,残留率为44.9%;多因素Logistic回归分析显示,BMI(OR=0.888,95%CI:0.808~0.975)、子宫位置(OR=1.836,95%CI:1.139~2.958)、人工流产次数(OR=2.258,95%CI:1.078~4.728)、阴道流血时长(OR=0.344,95%CI:0.141~0.837)、残留物最大径线(OR=1.061,95%CI:1.031~1.092)、残留物血流信号2级/3级(OR=3.636,95%CI:1.790~7.394;OR=4.001,95%CI:1.561~10.256)是宫腔残留的影响因素。结论 宫腔残留的高危因素有子宫后位、残留物最大径线、1次以上的人工流产、2级及以上的残留物血流信号,且血流信号等级影响最大。BMI和阴道流血时长>3周是宫腔残留的保护因素。
Objective To investigate the factors affecting uterine cavity repair and to provide a theoretical basis for the choice of expectant treatment for women with incomplete abortion.Methods From January to December 2021,534 patients with incomplete abortions were recruited at University of Hong Kong-Shenzhen Hospital,and their demographic characteristics and correlations from expulsion of the gestational sac to 3 weeks after medication abortion and after menstrual resumption were recorded,and the factors affecting uterine cavity repair in incomplete abortions were analyzed by multifactorial logistic regression.Results In 534 women,there were 240 cases of uterine cavity remnants after menstrual return,with a remnant rate of 44.9%;the results of multifactorial logistic regression analysis showed that BMI(OR=0.888,95% CI:0.808-0.975),uterine position(OR=1.836,95% CI:1.139-2.958),number of abortions(OR=2.258,95% CI:1.078-4.728),length of vaginal bleeding(OR=0.344,95% CI:0.141-0.837),maximum diameter of residuals(OR=1.061,95% CI:1.031-1.092),and residual blood flow signal grade 2/3(OR=3.636,95% CI:1.790-7.394;OR=4.001,95%CI:1.561-10.256)were influential factors for uterine residuals.Conclusions High-risk factors for uterine residuals are posterior uterus,the maximum diameter of residuals,more than one abortion,grade 2 or higher residual blood flow signal,and the grade of blood flow signal had the greatest effect.BMI and duration of vaginal bleeding >3 weeks are protective factors for uterine residuals.
目的 分析药物性牙龈增生(DGO)治疗中半导体激光及牙周基础治疗的应用效果,以期进一步提升DGO治疗有效性,促使患者快速康复。方法 分析于我院进行治疗的88例DGO患者基本资料,按照入院顺序使用奇偶号法将其等分为各44例的对照组和研究组,予对照组患者实施常规牙周基础治疗,予研究组患者实施牙周基础治疗联合半导体激光治疗,对比2组治疗相关数据。结果 治疗前2组患者牙龈增生指数(GHI)比较差异无统计学意义(P>0.05),经过治疗,研究组患者各阶段GHI均低于对照组,差异存在统计学意义(P<0.05);治疗前2组患者龈沟出血指数(SBI)、探诊深度(PD)以及菌斑指数(PLI)比较差异无统计学意义(P>0.05),经过治疗研究组各项治疗评分均比对照组更为理想,差异存在统计学意义(P<0.05);治疗后研究组总有效率为97.73%,对照组总有效率为81.82%,差异存在统计学意义(P<0.05)。结论 对DGO患者实施牙周基础治疗下的半导体激光干预能够在更大程度上改善患者病情,同时缩短治疗周期,提升治疗总有效率,应用效果理想,可在临床推广使用。
目的 探讨苏黄止咳胶囊联合多索茶碱对慢性持续期支气管哮喘的疗效及对肺功能、呼出气一氧化氮(FeNO)的影响。方法 选择2020年3月—2022年3月70例慢性持续期支气管哮喘患者,随机分为2组各35例,对照组仅予以多索茶碱治疗,研究组在对照组基础上加服苏黄止咳胶囊治疗。治疗3个月,采用哮喘控制测试(ACT)对患者进行评估,记录哮喘急性加重、急救药物使用情况及急诊入院情况,测定肺功能和呼出FeNO。结果 2组治疗1月的ACT评分比较无统计学意义(P>0.05),治疗2、3个月时研究组的ACT评分高于对照组(P<0.05)。研究组哮喘急性加重次数、急救药物使用次数均少于对照组(P<0.05),而2组急诊入院次数比较差异无统计学意义(P>0.05)。与基线值相比,2组治疗3个月时的肺功能指标无改变(P>0.05)且组间比较差异亦无统计学意义(P>0.05);2组治疗3个月时的FeNO无改变(P>0.05),而研究组的FeNO低于对照组(P<0.05)。结论 苏黄止咳胶囊联合多索茶碱治疗慢性持续期支气管哮喘可降低FeNO,提高哮喘控制水平。
Objective To investigate the effect of Suhuang Zhike capsule combined with doxofylline on chronic persistent bronchial asthma, pulmonary function and exhaled nitric oxide(FeNO).Methods Seventy patients with chronic persistent bronchial asthma from March 2020 to March 2022 were randomly divided into two groups, 35 cases in each group.The control group was only treated with doxofylline, and the study group was treated with Suhuang Zhike capsule additionally.After 3 months of treatment, the patients were evaluated by asthma control test(ACT), the acute exacerbation of asthma was recorded, and the pulmonary function and exhaled FeNO were measured.Results There was no statistical significance in the ACT score of the two groups after one month of treatment(P>0.05).The ACT scores of the study group after two months and three months of treatment were significantly higher than those of the control group(P<0.05).The times of acute exacerbation of asthma and the use of emergency drugs in the study group were less than those in the control group(P<0.05), but there was no significant difference in the number of emergency hospitalizations between the two groups(P>0.05).Compared with the baseline value, there was no significant change in lung function indexes in the two groups after 3 months of treatment(P>0.05).Compared with the baseline value, there was no significant change in FeNO in the two groups after 3 months of treatment(P<0.05), while FeNO in the study group was lower than that in the control group(P<0.05).Conclusions Suhuang Zhike capsule combined with doxofylline in the treatment of chronic persistent bronchial asthma can reduce FeNO and improve the level of asthma control.
目的 探讨与分析推拿联合补肾祛瘀针刺法治疗慢性腰肌劳损恢复期患者对腰部疼痛及表面肌电图的影响。方法 选择2019年9月—2022年4月我院收治的72例慢性腰肌劳损恢复期患者为研究对象,根据随机1∶1数字表法,分为联合组与对照组各36例。对照组给予推拿治疗,联合组在此基础上,给予补肾祛瘀针刺法治疗,2组均治疗并观察4周,评价腰部疼痛及表面肌电图变化情况。结果 治疗后联合组与对照组的总有效率分别为97.2%和75%,联合组高于对照组(P<0.05);治疗前,2组患者的视觉类比疼痛评分法(VAPS)和下腰痛失能问卷(OPDG)评分比较差异无统计学意义,治疗后,2组患者的VAPS和OPDG评分均降低,且联合组低于对照组(P<0.05);2组治疗后的腰椎前屈力度都高于治疗前(P<0.05),且联合组更高(P<0.05);2组治疗后的表面肌电图神经根振幅和潜伏期均低于治疗前(P<0.05),且联合组更低(P<0.05)。联合组与对照组治疗后的血清5-HT含量均高于治疗前(P<0.05),联合组更高(P<0.05)。结论 推拿联合补肾祛瘀针刺法在慢性腰肌劳损恢复期患者中的应用具有良好的安全性,有效改善患者的腰椎功能,缓解患者疼痛,提高整体治疗效果,也能改善患者的表面肌电图状况,促进血清5-HT的释放。
Objective To explore and analyze the effects of massage combined with kidney tonifying and blood stasis removing acupuncture on lumbar pain and surface electromyography in patients with chronic lumbar muscle strain in the recovery period.Methods From September 2019 to April 2022, 72 cases of patients in the recovery period of chronic lumbar muscle strain treated in our hospital were selected as the research objects, and were divided into the combined group and the control group with 36 cases in each group by the random 1∶1 number table method.The control group were given massage therapy, and the combination group were given kidney tonifying and stasis removing acupuncture additionally.Results After treatment, the total effective rates of combined group and control group were 97.2% and 75%, respectively, and the combined group was significantly higher than the control group(P<0.05).Before treatment, there was no significant difference in the visual analogue pain scale(VAPS)and Oswestry low pain & disability questionnaire(OPDG)scores between the two groups, but after treatment, the scores of the two groups were significantly decreased, and the combined group was significantly lower than the control group(P<0.05).The lumbar flexion intensity after treatment was significantly higher in both groups than before treatment(P<0.05), and higher in combination group(P<0.05).The amplitude and latency of surface electromyogram nerve roots after treatment were significantly lower in both groups than before treatment(P<0.05), and even lower in combination group(P<0.05).The serum 5-HT content in combination group and control group after treatment was significantly higher than that before treatment(P<0.05), and that in combination group was higher(P<0.05).Conclusions The application of massage combined with kidney tonifying and blood stasis removing acupuncture in patients recovering from chronic lumbar muscle strain has good safety, which can improve the lumbar function of patients, relieve the pain of patients, improve the overall therapeutic effect, improve the surface electromyography of patients and promote the release of serum 5-HT.
目的 分析年轻恒前牙活髓切断术中iRoot BP Plus和氢氧化钙的应用价值。方法 分析我院收治的年轻恒前牙活髓切断术治疗患者临床数据,对60例患者分组治疗,对照组使用氢氧化钙作为盖髓剂,研究组使用iRoot BP Plus作为盖髓剂,对比治疗相关数据。结果 研究组患者手术时间、术后肿胀时间以及疼痛时间较对照组更短(P<0.05);两组患者语言功能、咀嚼功能评分比较差异无统计学意义(P>0.05),而研究组患者固定、舒适以及美观程度评分较对照组更高(P<0.05);研究组治疗成功率为95.12%,略高于对照组成功率的79.55%(P<0.05)。结论 对接受年轻恒前牙活髓切断术治疗的患者采用iRoot BP Plus作为盖髓剂能够取得更为理想的效果,不仅可以有效改善患者牙齿功能,提升美观度,还能够减少操作时间,且成功率更高,可作为主要治疗方案纳入考量。
目的 探讨基于中药熏蒸配合穴位按摩的健康管理对稳定期肺肾气虚型慢阻肺的疗效。方法 选取2020年1月—2021年1月在我院接受治疗的稳定期肺肾气虚型慢阻肺患者120例为研究对象,随机分为对照组和干预组。对照组采用西医常规干预,干预组在此基础上实施为期1年的中药熏蒸配合穴位按摩的健康管理,比较干预前后2组患者肺功能、血氧指标以及生活质量的差异。结果 干预前,2组患者第1秒用力肺活量(FEV1)、第1秒用力肺活量占预计值百分比(FEV1%)、用力肺活量(FVC)、第1秒用力肺活量占用力肺活量的比值(FEV1/FVC%)等指标比较差异无统计学意义(P>0.05),干预后,2组患者的FEV1、FEV1%、FVC、FEV1/FVC%明显上升,且干预组患者优于对照组(P<0.05);实施相关干预前,干预组和对照组患者的血氧指标比较差异无统计学意义(P>0.05),干预后,2组患者的PaO2、和SpO2上升,PaCO2下降,且干预组的变化幅度大于对照组(P<0.05);干预前2组患者在圣乔治问卷(SGRQ)生活质量评分比较差异无统计学意义(P>0.05),干预后2组患者的SGRQ生活质量评分降低,且干预组患者的SGRQ生活质量指标评分更低(P<0.05)。结论 中药熏蒸配合穴位按摩应用于稳定期肺肾气虚型慢阻肺患者中,能够提高患者的肺功能,改善血氧指标,提高患者的生活质量。
Objective To explore the effect of health management based on traditional Chinese medicine fumigation combined with acupoint massage on stable chronic obstructive pulmonary disease(COPD)with lung-kidney deficiency.Methods A total of 120 patients with stable COPD and lung-kidney deficiency who received treatment in our hospital from January 2020 to January 2021 were selected as the study objects and randomly divided into control group and intervention group.The control group received conventional Western medicine intervention,and the intervention group received 1-year traditional Chinese medicine fumigation combined with acupoint massage on the basis of Western management.The differences of lung function,blood oxygen index and quality of life between the two groups were compared before and after intervention.Results Before intervention,there were no significant differences in forced expiratory volume in one second(FEV1),the first second forced vital capacity percentage of expected value(FEV1%),forced vital capacity(FVC),the ratio of the first second forced vital capacity of forced vital capacity(FEV1/FVC%)between the two groups(P>0.05),but after intervention,the FEV1,FEV1%,FVC,FEV1/FVC% of the two groups increased significantly,and those in the intervention group were better(P<0.05).Before the implementation of relevant intervention,there was no difference in blood oxygen index between the two groups(P>0.05).After the intervention,PaO2 and SpO2 of the two groups were significantly increased,while PaCO2 was significantly decreased,and the change in the intervention group was significantly greater(P<0.05).Before intervention,there were no significant differences in the quality of life scores of St George’s Respiratory Questionnaire(SGRQ)between the two groups(P>0.05).After intervention,the scores of SGRQ of the two groups were significantly decreased,and the scores of the intervention group were significantly lower(P<0.05).Conclusions Traditional Chinese medicine fumigation combined with acupoint massage can significantly improve lung function,blood oxygen index and life quality of stable COPD patients with lung-kidney deficiency.