临床诊疗

罗哌卡因与布比卡因应用于妊娠期高血压产妇剖宫产腰麻联合硬膜外麻醉的效果比较

Effect comparison between Ropivacaine and Bupivacaine applied in lumber and epidural anesthesia in hypertensive disorder complication pregnancy caesarean section

:69-71
 
目的 对比观察罗哌卡因及布比卡因应用于患有妊娠期高血压的产妇行剖宫产时腰麻联合硬膜外麻醉的临床效果。方法 将103例择期行剖宫产手术的妊娠期高血压患者随机分为罗哌卡因组51例及布比卡因组52例分别采用对应药物进行麻醉,研究两组阻滞效果、心血管系统变化情况及不良反应发生情况。结果 两组间麻醉镇痛效果及优良率比较,差异没有统计学意义(P>0.05)。罗哌卡因组感觉及运动阻滞起效时间较布比卡因组长,运动阻滞恢复时间较布比卡因组短(P<0.05)。心血管系统变化情况比较,麻醉5min、10min时两组收缩压及平均动脉压均降低,但布比卡因组波动更大,两组间比较差异显著(P<0.05),心率及血氧饱和度比较无差异(P>0.05)。罗哌卡因组不良反应出现时间较布比卡因组晚,同时其不良反应发生率较布比卡因组低(χ2=4.1599,P<0.05)。结论 罗哌卡因及布比卡因在阻滞时间上略有差异,麻醉镇痛效果相当,但鉴于妊高症产妇本身心血管系统存在基础问题,运用罗哌卡因对心血管系统的影响较小,安全性更高,更值得推荐使用。
论著

宫腔镜病灶切除术与超声监测下吸宫术治疗剖宫产瘢痕部位妊娠的有效性比较

Comparison of effectiveness between hysteroscopic resection surgery and ultrasound-guided uterine aspiration in the treatment of cesarean scar pregnancy

:500-504
 
       目的   比较宫腔镜病灶切除术与超声监测下吸宫术治疗剖宫产瘢痕部位妊娠(CSP)的有效性。   回顾性分析2021年7月—2023年10月在南宁市妇幼保健院确诊为I、Ⅱ型CSP并接受治疗的129例患者,停经时间在38~83 d,中位停经时间48 d。其中42例患者接受了宫腔镜病灶切除术治疗(A组),87例患者接受超声监测下吸宫术治疗(B组),比较两组患者术后1、3、7、14 d的人绒毛膜促性腺激素水平以及手术出血量、手术时间、住院时间、住院花费。结果   两组患者在术后1 d,血清HCG水平下降,下降幅度均超过50%,且A组患者术后1 d血清HCG的下降幅度及下降速率大于B组患者(P<0.05);术后3、7、14 d,两组血清HCG水平仍持续下降。另外,A组患者手术出血量、手术时间、住院时间、住院花费分别为(15.35±14.53)mL、(60.73±53.05)min、(4.33±1.90)d、(6 689.23±2 216.19)元;B组患者手术出血量、手术时间、住院时间、住院费用分别为(26.09±29.24)mL、(51.59±54.46)min、(4.82±1.83)d、(6 270.34±2 547.85)元。A组患者术中出血量低于B组、住院时间短于B组(P<0.05),手术时间及住院费用与B组比较差异无统计学意义(P均>0.05)。结论   宫腔镜病灶切除术与超声监测下吸宫术均能有效治疗CSP,但宫腔镜病灶切除术在术后血清HCG的下降幅度及下降速率、术中出血量、住院时间等方面优于超声监测下吸宫术,而且手术时间和住院费用并没有显著增加。
       Objective  To compare the efficacy between hysteroscopic  resection surgery and ultrasound-guided uterine aspiration in the treatment of cesarean scar pregnancy(CSP).Methods  A  retrospective analysis was performed in 129 patients diagnosed with CSP(type I or Ⅱ)and treated in Nanning Maternal and Child Health Hospital from July 2021 to October 2023.Their duration of amenorrhea was between 38~83 d,with a median of 48 days.Among them,42  patients were treated with hysteroscopic resection surgery therapy(group A),87 patients were treated with ultrasound-guided uterine aspiration therapy and(group B).Then,the levels of human chorionic gonadotropin(HCG),the amount of the intraoperative bleeding volume,surgical time,hospitalization time,and hospitalization expenses were compared between the two groups at one,three,seven and 14 days postoperativey.Results  After one day of surgery,the serum HCG levels of two groups significantly decreased,with a decrease of more than 50%,and the magnitude and  rate of  decrease in  serum HCG levels of group A were  significantly larger than those of group B(P<0.05);After three,seven,and 14 day of surgery,serum HCG levels continued to decrease.Furthermore,the intraoperative bleeding volume,surgical time,hospitalization time,hospitalization expenses in group A were(15.35±14.53)mL,(60.73±53.05)min,(4.33±1.90)d,(6 689.23±2 216.19)yuan,respectively.That in group B were(26.09±29.24)mL,(51.59±54.46)min,(4.82±1.83)d,(6 270.34±2 547.85)yuan,respectively.Compared to group B,the intraoperative bleeding volume of group A was significantly lower(P<0.05),and the hospitalization time is shorter,while there was no significant difference in surgical time and hospitalization expenses.Conclusions  Both of hysteroscopic resection surgery and ultrasound-guided uterine aspiration can treat cesarean scar pregnancy effectively,but the former is superior to the latter in terms of the magnitude and rate of decrease in serum HCG levels after surgery,intraoperative bleeding volume,and hospitalization time,with no significant increase in surgical time and hospitalization expenses.
论著

剖宫产后再次分娩阴道试产失败的影响因素

The influencing factors of failed vaginal trial delivery after cesarean section

:410-415
 
       目的   探讨剖宫产后再次分娩阴道试产失败的影响因素。方法   选取2021年5月—2024年5月在枣庄市妇幼保健院分娩的138例有剖宫产手术史的足月妊娠产妇进行回顾性分析。所有产妇依照其阴道试产结果将成功阴道分娩的35例产妇分为成功组,将阴道试产失败中转剖宫产的103例产妇分为失败组。对比两组产妇的妊娠结局、孕期情况及围产期情况,最后采用多因素Logistic回归分析法分析剖宫产后再次分娩阴道试产失败的影响因素。结果   两组产妇子宫破裂、胎儿窘迫、产褥感染及产后出血等妊娠不良结局总发生率对比差异无统计学意义(11.43% vs 6.80%,χ 2 =0.760,P=0.382 >0.05);通过对比两组产妇孕期情况发现,失败组与成功组孕妇年龄、孕次、身高、孕前体质量、妊娠期合并症、分娩前体质量指数(BMI)比较差异无统计学意义(P>0.05),失败组与成功组孕妇孕期体质量增长[(4.56±2.56)kg vs(12.45±3.24)kg]、分娩孕周[(39.46±1.25)周 vs(37.95±1.37)周]、阴道分娩史(8.57% vs 26.21%)、妊娠间隔时间[(2.74±0.35)年 vs(3.37±0.57)年]及瘢痕厚度[(4.51±0.56)mm vs(5.42±0.38)mm],对比差异有统计学意义(t=3.497,P<0.001;t=5.755,P<0.001;χ 2 =4.780,P=0.029;t=6.148,P<0.001;t=10.764,P<0.001);通过对比两组产妇围产期情况发现,失败组与成功组新生儿性别、是否镇痛比例比较差异无统计学意义(P>0.05),失败组与成功组孕妇产前新生儿估重[(3352.31±153.67)g vs(3046.25±141.68)g]、是否引产[60.00% vs 52.43%]、胎膜早破[11.43% vs 35.92%]、入院时是否临产[857% vs 27.18%],对比差异有统计学意义(t=10.805,P<0.001;χ 2 =7.330,P=0.007;χ 2 =7.500,P=0.006;χ 2 =5.200,P=0.023);以阴道试产情况作为因变量(失败=1,成功=0)纳入Logistic回归模型,结果显示,分娩孕周过晚、产前新生儿估重过高、引产及入院时未临产为剖宫产后再次分娩阴道试产失败的影响因素P<0.05)。结论   分娩孕周过高、产前新生儿估重过高、引产及入院时未临产为剖宫产后再次分娩阴道试产失败的独立影响因素,需针对分娩孕周、产前新生儿估重过高的剖宫产后再次分娩阴道试产产妇给予高度关注并采取相应措施进行干预,同时自然临产能够降低阴道试产失败风险,但针对具有引产指征的产妇,依然需要及时引产。
       Objective   To explore the influencing factors of vaginal trial delivery failure after cesarean section.Methods   A retrospective analysis was conducted on 138 full-term pregnant women with a history of cesarean section who gave birth in our hospital from May 2021 to May 2024.All women were divided into two groups according to the  results of their vaginal trial delivery.Based on their vaginal trial results,35 parturients who successfully delivered were divided into the successful group,and 103 parturients who failed vaginal trial delivery and transitioned to cesarean section were divided into the failed group.The pregnancy outcomes of postpartum women and the pregnancy and perinatal conditions were compared between the two groups,and multivariate Logistic  regression analysis was used to analyze the independent influencing factors of vaginal trial delivery failure after cesarean section.Results   There was no significant difference in the total incidence of adverse pregnancy outcomes such as uterine rupture,fetal distress,postpartum infection,and postpartum hemorrhage between the two groups of parturients (P>0.05).By comparing the pregnancy status of two groups of  pregnant women,it was found that there was no difference (P>0.05).The average weight gain during pregnancy of failure and successful group,gestational age,cases with vaginal delivery history,intervalbetween pregnancy and scar thickness,the contrast difference was significant (all P<0.05) .By comparing the perinatal situation of the two groups,there was no difference in the sex of fetus and analgesia receiving of parturients between the failed group and the successful group (P>0.05),while there is difference in weight estimation,whether induced labour,premature  rupture of fetal membrane,whether admitted to hospital (all P<0.05).Vaginal trial delivery was set as the dependent variable (failure=1,success=0) and it was incorporated into the Logistic regression model.The results showed that high gestational age during delivery,high estimated weight of fetus before delivery,induction of labor,and non-labor upon admission were independent influencing factors for vaginal trial delivery failure after cesarean section (P<0.05).Conclusions  Excessive gestational age,high estimated weight of fetus before delivery,induced labor,and non-labor upon admission were independent influencing factors for the failure of vaginal trial delivery after cesarean section.It is necessary to pay high attention and take corresponding measures to intervene in women who have undergone vaginal trial delivery after cesarean section due to excessive gestational age and high estimated weight of fetus before delivery.At the same time,spontaneous labour can reduce the risk of vaginal trial delivery failure.However,for women with indications for induced labor,timely induction is still necessary.
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