论著
目的 探讨妇科肿瘤围手术期发生静脉血栓栓塞症(VTE)的高危因素及预防措施。方法 回顾性分析2018年1月—2021年5月于中山市人民医院妇科收治的围手术期VTE患者38例(9例术前发生血栓、29例术后发生血栓)的临床特征、诊疗过程,并根据高危因素提出针对性的预防措施。结果 9例术前血栓的患者,其中恶性肿瘤、血浆D-二聚体阳性(>500 mg/L)与对照组比较差异有统计学意义(P<0.05),而年龄、BMI、合并内科疾病与对照组比较,差异无统计学意义(P>0.05);29例术后血栓的患者,BMI>25 kg/m2、恶性肿瘤、合并内科疾病、手术时间大于3小时、术后使用止血药物与对照组比较差异有统计学意义(P<0.05);而年龄与手术方式与对照组比较差异无统计学意义(P>0.05)。结论 恶性肿瘤、血浆-D二聚体阳性、手术时间大于3小时、术后使用止血药物均为妇科围手术期血栓发生的高危因素,针对上述高危因素积极预防可显著降低VTE的发生。
Objective To study the high-risk factors and preventive measures of venous thromboembolism in gynecological periopreative surgery.Methods The clinical characteristics and the diagnosis and treatment of thirty-eight cases with perioperative deep venous thrombosis(nine cases with preoperative deep venous thrombosis and twenty-nine cases with postoperative deep venous thrombosis)in the department of gynecology of Zhongshan People's Hospital were analyzed retrospectively.Targeted preventive measures were put forward according to high risk factors.Results Compared with the control group,there were significance differences in malignant tumor,positive D-dimer(>500 mg/L)in nine cases with preoperative thrombosis(P<0.05),but no significance differences in age,body mass index(BMI),complicated with internal diseases(P>0.05).BMI>25,malignant tumor,complicated with internal diseases,operation time more than 3 hours,postoperative usage of hemostatics in twenty-nine cases with postoperative deep venous thrombosis had statistical significance compared with the control group(P<0.05).But age and surgery method had no statistical significance(P>0.05)between the two groups.Conclusions Malignant tumor,positive D-dimer(>500 mg/L),operation time more than 3 hours,postoperative usage of hemostatics were the high-risk factors in gynecological periopreative surgery,active prevention against these high-risk factors can significantly reduce the incidence of venous thromboembolism.
论著
目的 调查儿科急诊非急诊手术患儿输血后红细胞恢复的影响因素。方法 回顾2020年1月—2020年12月期间广州市妇女儿童医疗中心珠江新城院区儿科急诊1月~18岁患儿的输血情况,其中分为Hb提升达预期组(n=93),Hb提升未达预期组(n=156),根据年龄、性别、体质量、是否恶性肿瘤、是否发热、有无延迟输血、输血前血红蛋白水平、输注红细胞类型情况,分析输血疗效及影响因素。结果 2组患儿的性别、年龄、体质量、有无恶性肿瘤、是否发热、输血等待时间、输血前后血红蛋白值、输注红细胞悬液量以及有无及时输血均无统计学差异;输注红细胞类型组间存在显著差异,Hb提升未达预期组更多输注了洗涤红细胞悬液(13.5% vs 5.4%,P=0.044),输血后 Hb 值较低(中位数,73 g/L vs 84 g/L,P<0.001),变化 Hb 值较小(中位数,18 g/L vs 30 g/L,P<0.001),归因分析未发现影响因素。结论 输注洗涤红细胞可能是降低输血后红细胞提升的影响因素,输注洗涤红细胞时需严格输血指征同时注意红细胞提高预值的设定。
Objective To investigate the influencing factors of blood transfusion efficacy in patients without emergency operations in pediatric emergency.Methods A retrospective analysis of the blood transfusion of pediatric emergency children(1 month~ 18 year of age)in Zhujiang New Town Branch of Guangzhou Women and Children's Medical Center from January 2020 to December 2020 was carried out,patients were divided into Hb elevation up to expectation group(n=93)and Hb elevation not up to expectation group(n=156).The efficacy of blood transfusion and the factors affecting it were analyzed according to age,gender,body mass,with or without malignant tumor,whether fever was present,whether there was delayed transfusion,pre-transfusion hemoglobin level,and the type of red blood cells transfused.Results There were no significant differences in gender,age,weight,malignant tumor,fever,waiting time for blood transfusion,hemoglobin level before and after blood transfusion,infusion volume of red blood cell suspension and whether had timely blood transfusion between the two groups.Significant differences were found between groups of transfused red blood cell types,with more washed red blood cell suspensions transfused in the Hb elevation not meeting expectations group(13.5% vs 5.4%,P=0.044),which had lower post-transfusion Hb values(median,73 g/L vs 84 g/L,P<0.001),and smaller change Hb values(median,18 g/L vs 30 g/L,P<0.001),and attribution analysis did not reveal influencing factors.Conclusions Transfusion of washed red blood cell may be an influencing factor that reduces the RBCs elevation after transfusion.Attention should be paid to strict indications for washed red blood cell transfusion and setting the expected Hb level.
论著
目的 分析华北地区某医院院前急救医疗服务的资源利用状况,并依据相关影响因素针对院前急救医疗服务过程中存在问题提出相应对策。方法 收集2021年3月—2022年4月期间就诊于华北地区某医院急诊科患者的一般资料、就诊过程、症状特征。依据是否接受过院前急救服务、是否为疾病急性发作的危重症患者将患者分为4组,分析比较4组患者在一般资料、疾病病症特点两个方面是否存在统计学差异,探索影响院前急救医疗资源合理利用的相关因素。结果 本研究总计收纳患者病例5 800例,其中接受院前急救医疗服务的患者共840例占总调查人数的14.5%,其中危重症患者530例(63.1%),非危重症患者310例(36.9%);未接受院前急救医疗服务的患者为4 960例占总调查人数的85.5%,其中危重症患者803例(16.2%)。对所得数据采用多因素回归方法分析得知,在急诊科接受的危重症患者中急性胸痛与突发性头痛是选择不使用院前急救医疗措施的独立影响因素。在非危重症患者中发热、外伤、腹痛是非急重症患者接受院前急救医疗服务的独立影响因素。结论 院前急救医疗服务资源的提供与利用在实际应用的过程中存在资源闲置与服务空缺的问题。危重症患者在入院前仍有较大比例的患者没有选择接受院前急救医疗服务。该情况表明当前居民对危重症患者危重症状及院前急救医疗服务了解与认知不足,对此有必要加强对居民关于院前急救服务的科普宣教工作,并借助现有医疗服务力量支持院前急救医疗服务的规范与准则,这对保障患者生命安全,争取危重症患者存活机会,促进急救资源合理利用具有重要意义。
Objective To analyze the resource utilization status of pre-hospital emergency medical services in a hospital in North China,and to propose corresponding countermeasures for problems in the process of pre-hospital emergency medical services according to relevant influencing factors.Methods From March 2021 to April 2022,the general data,treatment process and symptom characteristics of patients who were treated in the emergency department of a hospital in North China were collected.According to whether they had received pre-hospital emergency services and whether they were critically ill patients with acute onset of disease,the patients were divided into four groups.Whether there were statistical differences in the general data and disease characteristics of the four groups of patients,and the relevant factors affecting the rational utilization of pre-hospital emergency medical resources were explored.Results This study included 5 800 patients,of which 840 patients receiving pre-hospital emergency medical services,accounted for 14.5% of the total survey,including 530(63.1%)and 310 non-critically ill patients(36.9%);4 960 patients not receiving pre-hospital emergency medical services accounted for 85.5% of the total survey,including 803(16.2%)of critically ill patients.Analysis by multivariate regression methods on the obtained data showed that acute chest pain and sudden headache in critically ill patients in the emergency department were independent influencing factors in choosing not to use pre-hospital emergency medical measures.Fever,trauma,and abdominal pain in non-critically ill patients were independent factors influencing the reception of pre-hospital emergency medical services.Conclusions The provision and utilization of pre-hospital emergency medical service resources have the problem of idle resources and service vacancies in the process of practical application.A significant proportion of critically ill patients still do not choose to receive pre-hospital emergency medical services before admission.This situation shows that the current residents have insufficient understanding and cognition of critical symptoms and pre-hospital emergency medical services,and it is necessary to strengthen the scientific popularization and education of residents on pre-hospital emergency services,and support the norms and guidelines of pre-hospital emergency medical services with the help of existed medical services,which is of great significance for ensuring the safety of patients' lives,striving for the survival opportunities of critically ill patients,and promoting the rational use of emergency resources.
论著
目的 分析新生儿无乳链球菌(B族链球菌,GBS)败血症的临床特点、围产期高危因素及预后,提高临床对GBS败血症的认识。方法 选择21例GBS败血症新生儿(收集病例时间为2018年2月—2021年11月),采用回顾性调查法分析临床资料;对新生儿临床资料、实验室检查、影像学资料进行统计和对比,分析临床特征,同时比较患儿合并症情况及评估治疗预后结果等。结果 GBS败血症新生儿中早发型(90.48%)明显高于迟发型(9.52%),P<0.05;GBS败血症新生儿主要症状表现为发热、发绀、气促、呻吟、抽搐等,以气促、呻吟为主;通过实验室检查,发现患儿普遍存在C反应蛋白、降钙素原、白细胞计数等指标异常情况;经头颅MRI检查提示蛛网膜下腔出血6例;X线提示新生儿吸入性综合征6例、双肺新生儿肺炎4例;部分患儿存在合并症,其中1例合并脑膜炎、3例合并蛛网膜下腔出血、4例合并黄疸、2例合并新生儿低血糖;所有患儿接受抗菌药物治疗,以青霉素、头孢他啶为主,平均住院时间(14.86±2.33)d,治愈19例(占比90.48%)、1例患儿好转后家属要求签字出院,1例家属要求转上级儿童医院。结论 新生儿无乳链球菌败血症有早发型和迟发型之分,两者的临床表现及特征有明显差异,该病病情较凶险,临床需高度重视本病的防治工作,早期诊断及时治疗干预,以提高新生儿预后。
Objective To analyze the clinical characteristics,perinatal high-risk factors and prognosis of neonatal Streptococcus agalactiae(group B Streptococcus,GBS)sepsis,and to improve the clinical understanding of Streptococcus agalactiae sepsis.Methods Twenty-one newborns with GES sepsis were selected(the cases were collected from February 2018 to November 2021),and the clinical data were analyzed by retrospective investigation.The clinical data,laboratory examination and imaging data of newborns were summarized and compared,and the clinical characteristics were analyzed.At the same time,the complications of children were compared and the prognosis of treatment was evaluated.Results In newborns with GBS sepsis,the early-onset rate(90.48%)was significantly higher than the late-onset(9.52%),P < 0.05.The main symptoms of newborns with GBS sepsis were shortness of breath,moaning,fever,cyanosis,convulsions,etc.Through laboratory examination,it was found that there were common abnormalities in C-reactive protein,procalcitonin,leukocyte count and other indicators in children.Transcranial MRI results showed 6 cases with subarachnoid hemorrhage;X-ray showed 6 cases with neonatal aspiration syndrome and 4 cases with both lungs neonatal pneumonia.Some children had complications,including 1 case with meningitis,3 cases with subarachnoid hemorrhage,4 cases with jaundice,and 2 cases with neonatal hypoglycemia.All children were treated with antibiotics,mainly penicillin and ceftazidime.The average hospital stay was(14.86 ± 2.33)days,and 19 cases were cured(accounting for 90.48%).One case of the child's family member asked to sign and leave the hospital after improvement,and one case of the family member asked to be transferred to a superior children's hospital.Conclusions Neonatal Streptococcus agalactiae sepsis can be divided into early-onset and late-onset type.There are significant differences in clinical manifestations and characteristics between them.The disease is dangerous,clinical attention should be paid to the prevention and treatment of the disease,early diagnosis and timely treatment and intervention,so as to improve the prognosis of newborns.
论著
目的 调查眼科患者对荧光素眼底血管造影认知情况及健康教育需求,为眼底造影医护人员实施高效、个性化健康教育提供依据。方法 采用自制眼底造影认知及健康教育需求问卷,对本院2021年6月—8月的123例眼底血管造影患者进行问卷调查,使用Spearman相关性分析、非参数秩和检验及多元线性逐步回归分析患者眼底血管造影认知的影响因素。结果 患者荧光素眼底血管造影认知得分为(33.77±8.09)分,其中,患者对于检查中的相关知识认知最低,相对得分为0.59;患者健康教育需求的得分为(43.95±7.63)分,其中,检查后的相关知识需求度最高,相对得分为0.77;不同年龄、文化程度、主要照顾者、眼造影检查次数及是否合并全身病的患者的认知水平差异有统计学意义(P<0.05)。多元线性逐步回归分析表明,眼造影检查史是患者眼底血管造影认知的独立影响因素。结论 眼科患者对荧光素眼底血管造影认知水平较低,健康教育需求高,医护人员应重视健康教育的实施,结合FFA操作流程及患者特点,制定标准化健康教育流程,探索有效的线上+线下的健康教育模式,以提高造影患者认知水平,保障患者安全。
Objective To investigate fundus fluorescein angiography(FFA)cognition and health education needs in ophthalmic patients,and to provide basis for efficient and personalized health education for FFA medical staff.Methods A self-made questionnaire was used in a survey of 123 patients from June to August 2021.The influencing factors of FFA cognition were analyzed by Spearman correlation analysis,non parametric rank sum test and multiple linear stepwise regression.Results The score of FFA cognition was(33.77 ± 8.09).Patients had the lowest cognition of relevant knowledge during the examination,with a relative score of 0.59.The score of patient's health education needs was(43.95 ± 7.63),while the score of relevant knowledge needs after examination was the highest,with a relative score of 0.77.There were significant differences in cognitive level among patients with different ages,educational levels,main caregivers,angiographic times,and complication of systemic diseases(P<0.05).Multiple linear stepwise regression analysis showed that the number of ocular angiography was an independent factor affecting the cognition of FFA.Conclusions Patients with FFA have low cognitive level and high demand for health education.Medical staff should pay attention to the implementation of health education,formulate a standardized health education process with the combination of operation process and patient characteristics,and explore an effective online-to-offline health education mode,so as to improve the cognitive level of angiography patients and ensure the safety of patients.
临床诊疗
目的 探讨柳州市老年骨质疏松性骨折(OPF)现状及其发生的危险因素。方法 回顾性分析2018年1月—2020年12月柳州市工人医院创伤中心收治的5 235例60周岁及以上老年OPF患者的临床资料,并从中随机抽取300例老年OPF患者临床资料作为研究组;选取同时期接诊的老年骨质疏松未骨折的300例患者临床资料作为对照组,通过医院病案管理系统,详细收集2组患者各项临床资料,分析柳州市老年OPF现状及危险因素。结果 5 235例老年OPF患者中,以胸腰椎压缩性骨折占比最高58.19%、其次为股骨颈骨折15.42%;60~74岁年龄段患者以胸腰椎压缩性骨折占比最高77.03%,75~89年龄段患者股骨颈骨折、粗隆间骨折占比均较高分别为43.36%、41.34%,≥90岁患者粗隆间骨折占比最高49.25%;男性、女性均以胸腰椎压缩性骨折占比较高,分别为46.34%、62.47%。经单因素/多因素分析显示,年龄、性别、体质量指数(BMI)、跌倒史、骨折史、骨密度(BMD)、糖尿病、不良生活习惯为老年OPF发生的独立危险因素(P<0.05)。结论 胸腰椎压缩性骨折是柳州市老年OP患者骨折的主要类型;老年OPF的发生与年龄、性别、BMI、跌倒史、骨折史、BMD 、糖尿病、不良生活习惯等因素有关,应采取积极预防措施,降低OPF的发生风险。
论著
目的 评价银杏二萜内酯葡胺注射液(DGMI)联合依达拉奉右崁对急性缺血性脑卒中(AIS)的治疗效果。方法 回顾性分析我院2021年3月—2022年6月收治的86例AIS患者,根据治疗方法不同,分为单药组和联合组,每组43例,2组均予以DGMI治疗,联合组加用依达拉奉右崁醇。对比2组的治疗效果。结果 治疗后,联合组美国国立卫生研究院卒中量表(NIHSS)评分低于单药组(P<0.05),简易智能精神状态检查量表(MMSE)和Barthel指数(BI)得分高于单药组(P<0.05);联合组治疗后脑血流动力学指标(Qmin和Vmin)高于单药组(P<0.05),而全血还原黏度、血浆黏度和血小板聚集指数低于单药组(P<0.05);联合组治疗后血清丙二醛(MDA)、超敏C-反应蛋白(hsCRP)和白细胞介素-6(IL-6)低于单药组(P<0.05),而超氧化物歧化酶(SOD)高于单药组(P<0.05);联合组治疗总有效率88.37%,高于单药组的67.44%(P<0.05),且2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论 DGMI联合依达拉奉右崁醇可有效提高AIS患者的神经功能、认知功能及日常生活能力,降低血液高凝状态,改善脑部血流,缓解机体氧化应激及炎症反应,且不良反应发生率较低,安全性良好。
Objective To evaluate the clinical efficacy of diterpene ginkgolides meglumine injection(DGMI)combined with edaravone dextracanthol in the treatment of acute ischemic stroke(AIS).Methods A total of 86 patients with AIS admitted to our hospital from March 2021 to June 2022 were divided into single drug group and combination group according to different treatment methods,with 43 patients in each group.Both groups were treated with DGMI,and the combination group was added with edaravone dextracanthol.The therapeutic effect,neurological function and adverse reactions of the two groups were compared.Results After treatment,compared with the single drug group,the NIH Stroke Scale(NIHSS)score of the combination group was significantly lower(P<0.05),and the Mini-Mental State Examination(MMSE)and Barthel index(BI)scores were significantly higher(P<0.05).After treatment,the cerebral hemodynamic indexes(Qmin and Vmin)in the combination group were significantly higher(P<0.05),while the whole blood reducing viscosity,plasma viscosity and platelet aggregation index were significantly lower(P<0.05).After treatment,compared with the single drug group,the serum malondialdehyde(MDA),high sensitive C-reactive protein(hsCRP)and interleukin- 6(IL-6)levels in the combination group were significantly lower(P<0.05),while the level of superoxide dismutase(SOD)was significantly higher(P<0.05).The total effective rate of the combination group was 88.37%,which was significantly higher than 67.44% of the single drug group(P<0.05).The incidence of adverse reaction between two groups was not significant(P>0.05).Conclusions DGMI combined with edaravone dextracanthol can effectively improve the neurological function,cognitive function and daily living ability of patients with AIS,reduce blood hypercoagulability,improve cerebral blood flow,alleviate oxidative stress and inflammatory reaction,improve the therapeutic effect,without increasing the incidence of adverse reactions,which has good safety.
论著
目的 探讨不同分期的子宫内膜异位症(EMs)患者行体外受精-胚胎移植(IVF-ET)助孕结局与成本效果分析。方法 回顾性分析2016年1月—2022年1月Ⅰ~Ⅱ期、Ⅲ~Ⅳ期EMs患者应用卵泡期长方案及同期因“输卵管因素”患者采用黄体期长方案行IVF-ET的助孕结局以及成本费用。结果 EMs各组的启动日LH、E2以及hCG日E2水平低于对照组(P<0.05),Ⅲ~Ⅳ期EMs组的可利用胚胎数、着床率、临床妊娠率、活产率明显低于对照组及Ⅰ~Ⅱ期EMs组(P<0.05),其流产率偏高,但组间比较差异无统计学差异(P>0.05)。各组间的Gn剂量、Gn天数、hCG日的LH水平、hCG日≥14 mm卵泡数、hCG日子宫内膜厚度、获卵数、受精率、卵裂率比较差异无统计学意义(P>0.05)。成本效果分析提示:各组平均周期总成本无明显差异,Ⅰ~Ⅱ期EMs组患者患者获得一例妊娠所花费的成本与对照组相当,而Ⅲ~Ⅳ期EMs组患者获得一例妊娠所花费的成本最高。结论 对于不同分期的EMs,Ⅰ~Ⅱ期患者应用卵泡期长方案的患者可获得良好的妊娠结局,其妊娠率及成本与传统方案相当,而Ⅲ-Ⅳ期的患者妊娠率偏低,获得妊娠的成本更高,可能与该疾病严重程度及方案选择有关。
Objective To analyze the outcome and cost-effectiveness of invitrofertilization-embryotransfer(IVF-ET)assisted pregnancy in endometriosis(EMs)patients with different stages.Methods The outcomes and costs of patients with stageⅠ-Ⅱ and Ⅲ-Ⅳ EMs treated with follicular phase long protocol and patients treated with luteal phase long protocol due to“tubal factors” during the same time from January 2016 to January 2022 were retrospectively analyzed.Results The levels of LH,E2 on initiation day and the levels of E2 on hCG day in EMs groups were lower than those in control group(P<0.05),the number of available embryos,implantation rate,clinical pregnancy rate and live birth rate in stage Ⅲ-Ⅳ EMs group were significantly lower than those in control group and stageⅠ-Ⅱ EMs group(P<0.05),and the abortion rate was higher.But there was no significant difference between groups(P>0.05).There were no significant differences in the dosage of Gn,duration of Gn,the levels of LH on hCG day,the number of follicles with diamete≥14 mm on hCG day,endometrial thickness on hCG day,number of oocytes retrieved,fertilization rate and cleavage rate among the three groups(P>0.05).Conclusions For different stages of endometriosis,patients in stageⅠ-Ⅱ who apply the follicular phase long protocol can achieve good pregnancy outcomes,and their pregnancy rate and cost are comparable to the traditional regimen,while patients in stage Ⅲ-Ⅳ have a low pregnancy rate,and the cost of pregnancy is higher,which should be related to the severity of the disease and the choice of regimen.
论著
目的 探讨胆固醇胆囊息肉形成的高危因素。方法 将广州市第一人民医院住院的219例接受腹腔镜胆囊切除的患者按照术后胆囊病理结果分为胆固醇息肉组(162例)和非胆固醇息肉组(57例)。对所有研究对象的年龄、性别、血脂水平、肝功、超敏C反应蛋白、CA199、癌胚抗原(CEA)、胆囊结石病史、糖尿病病史、肝硬化病史进行数据收集及统计学处理。结果 经非参数检验方法Mann-Whitney U分析结果显示:1. 脂代谢相关指标在胆固醇息肉组和非胆固醇息肉组间比较差异有统计学意义;2. 总胆固醇指标在胆固醇息肉组高于非胆固醇息肉组,且高于参考值范围;3. 胆固醇息肉组和非胆固醇息肉组比较部分脂代谢指标有统计学意义,但均在参考值范围内。胆固醇息肉形成的Logistic回归分析:得到的Logistic模型差异有统计学意义,χ2=179.14,P<0.001。模型纳入的8个自变量中,总胆固醇每增加一个单位,发生胆固醇息肉的风险相比于非胆固醇息肉组将增加38.2倍(P<0.05)。结论 总胆固醇是胆囊胆固醇息肉形成的高危因素。
Objective To investigate the risk factors of cholesterol polyps formation.Methods The 219 patients who underwent laparoscopic cholecystectomy in Guangzhou First People's Hospital were divided into cholesterol polyps group(162 cases)and non-cholesterol polyp group(57 cases)according to postoperative gallbladder pathological results.The age,gender,blood lipids levels,liver function,high-sensitivity C-reactive protein,CA199,carcinoembryonic antigen(CEA),history of gallstones,diabetes,and liver cirrhosis of all patients were collected and statistically processed.Results Mann-Whitney U analysis by nonparametric test method showed that the lipid metabolism-related indexes were significantly different between the cholesterol polyps group and the non-cholesterol polyp group.The total cholesterol indexes in the cholesterol polyps group were higher than those in the non-cholesterol polyp group,and higher than the reference range.The cholesterol polyps group and the non-cholesterol polyp group had statistical significance in some lipid metabolism indexes,but they were all in the normal range.Logistic regression analysis of cholesterol polyps formation showed the obtained Logistic model was statistically significant,χ2=179.14,P<0.001.Among the 8 independent variables included in the model,total cholesterol was statistically significant.For each unit increased in total cholesterol,the risk of developing cholesterol polyps increased by 38.2 times compared with the non-cholesterol polyp group.Conclusions Total cholesterol is a high risk factor for the formation of cholesterol gallbladder polyps.
论著
目的 探讨影响宫腔修复的因素,为不全流产妇女选择期待治疗提供理论依据。方法 2021年1月—12月在香港大学深圳医院招募早孕药流不全的患者534例,记录其人口学特征以及从排胎到流产后3周到月经复潮后的相关情况,通过多因素Logistic回归分析影响不全流产者宫腔修复的因素。结果 534例药流不全患者中,月经复潮后宫腔残留240例,残留率为44.9%;多因素Logistic回归分析显示,BMI(OR=0.888,95%CI:0.808~0.975)、子宫位置(OR=1.836,95%CI:1.139~2.958)、人工流产次数(OR=2.258,95%CI:1.078~4.728)、阴道流血时长(OR=0.344,95%CI:0.141~0.837)、残留物最大径线(OR=1.061,95%CI:1.031~1.092)、残留物血流信号2级/3级(OR=3.636,95%CI:1.790~7.394;OR=4.001,95%CI:1.561~10.256)是宫腔残留的影响因素。结论 宫腔残留的高危因素有子宫后位、残留物最大径线、1次以上的人工流产、2级及以上的残留物血流信号,且血流信号等级影响最大。BMI和阴道流血时长>3周是宫腔残留的保护因素。
Objective To investigate the factors affecting uterine cavity repair and to provide a theoretical basis for the choice of expectant treatment for women with incomplete abortion.Methods From January to December 2021,534 patients with incomplete abortions were recruited at University of Hong Kong-Shenzhen Hospital,and their demographic characteristics and correlations from expulsion of the gestational sac to 3 weeks after medication abortion and after menstrual resumption were recorded,and the factors affecting uterine cavity repair in incomplete abortions were analyzed by multifactorial logistic regression.Results In 534 women,there were 240 cases of uterine cavity remnants after menstrual return,with a remnant rate of 44.9%;the results of multifactorial logistic regression analysis showed that BMI(OR=0.888,95% CI:0.808-0.975),uterine position(OR=1.836,95% CI:1.139-2.958),number of abortions(OR=2.258,95% CI:1.078-4.728),length of vaginal bleeding(OR=0.344,95% CI:0.141-0.837),maximum diameter of residuals(OR=1.061,95% CI:1.031-1.092),and residual blood flow signal grade 2/3(OR=3.636,95% CI:1.790-7.394;OR=4.001,95%CI:1.561-10.256)were influential factors for uterine residuals.Conclusions High-risk factors for uterine residuals are posterior uterus,the maximum diameter of residuals,more than one abortion,grade 2 or higher residual blood flow signal,and the grade of blood flow signal had the greatest effect.BMI and duration of vaginal bleeding >3 weeks are protective factors for uterine residuals.