目的 研究并分析优质护理对消化性溃疡患者的临床疗效以及护理满意度的影响。方法 入选2014年8月—2015年10月收治的184例消化性溃疡患者作为研究对象, 根据电脑随机数字将患者随机分为研究组和对照组,各92例。对照组男50例,女42例,年龄18～60 a,平均年龄(43.7±2.1)a,病程2～10 a,平均(5.2±0.4)a,研究组男48例,女44例,年龄20～59 a,平均(42.3±3.6)a,病程2～10 a,平均(5.2±0.4)a。患者入院后均给予消化性溃疡常规基础治疗(四联疗法),在此基础上给予对照组患者常规护理,研究组患者优质护理,对比两组患者的临床疗效和护理满意度。结果 经研究观察对比,研究组消化性溃疡患者的临床疗效明显优于对照组,研究组消化性溃疡患者的总有效率为95.65%,对照组为79.35%,两组数据对比差异有统计学意义(P＜0.05)。研究组患者治疗后烧心、上腹痛、嗳气等症状减轻明显较对照组显著,所需时间更短,胃镜检查显示研究组患者经优质护理处理后溃疡愈合时间明显缩短,愈合明显优于对照组,上述对比差异有统计学意义(P＜0.05)。研究组护理满意度为96.74%,对照组护理满意度仅83.69%,研究组高于对照组,差异有统计学意义(P＜0.05)。结论 优质护理能够明显缩短溃疡愈合时间,促进患者痊愈,提高消化性溃疡患者的疗效和护理满意度,值得临床推广和应用。

Objective To study and analyze the effect of high quality nursing on curative effect of patients with peptic ulcer and nursing satisfaction. Methods 98 cases of peptic ulcer patients income for treatment from August 2014 to October 2015 were selected as study subjects. The patients were randomly divided into study group and control group, 49 cases in each group. The control group included male 28 case,female 21 case,aged 18～60 years old, average age (43.7±2.1) years, disease duration of(2～10)years, average(5.2±0.4) years.Study group included male 24 cases, female 25 cases, aged 20～59 years old, average age (42.3±3.6) years, disease duration of (2～10) years, average (5.2±0.4) years. After the patient was admitted to hospital, they were treated with digestive ulcer routine treatment (quadruple therapy). On this basis,patients in the control group were given routine nursing care, the study group patients with high quality nursing, compared with the two groups of patients with clinical efficacy and nursing satisfaction. Results Study group patients with peptic ulcer clinical, curative effect was obviously superior to the control group. The study group patients with peptic ulcer, total efficiency was 95.91%, It was 79.59% in the control group, the difference between the data of two groupshad statistical significance (P<0.05). Study group nursing satisfaction was 97.96%, the control group was only81.63%. The study group was significantly higher than the control group, the difference was statistically significant (P<0.05). Quality care may significantly shorten the average length of stay in patients, the difference was statistically significant (P<0.05). Conclusion High quality nursing may significantly shorten the average length of stay in patients with peptic ulcer, improve the curative effect of peptic ulcer patients and nursing satisfaction. It is worthy of clinical popularization and application.

目的 通过对我院健康体检人群眼科体检的数据分析,探讨眼科健康管理对眼部疾病防治的重要性。方法 分析2015年1月—12月眼科体检人群的数量、来源、性别、年龄。分析各类眼部疾病的检出率及不同年龄、性别的分布情况。结果 眼科疾病主要为屈光不正、结膜炎、白内障、眼底动脉硬化、黄斑变性等。屈光不正多以青壮年为主,结膜炎在中老年人群中检出率较高,白内障及眼底疾病的检出率在中老年人群中随年龄的增加而增加。结论 对于常见病和隐匿性疾病的防治,眼科体检具有较好的指导意义。

Objective Through the data analysis of eye common diseases in our hospital physical examination population to discuss the importance of eye health management for eye common disease prevention and control. Methods To analyze the quantities, source, gender and age of the eye examination population from Jan to Dec 2015.To analyze relevance ratio of all kinds of eye common disease and the distribution of different age and gender. Results Ophthalmic diseases included mainly ametropia, conjunctivitis, cataracts,fundus arteriosclerosis,macular degeneration and so on. Ametropia mainly happened at young adults, conjunctivitis detection rate was higher in the elderly crowd. The detection rate of cataract and retinal diseases in the elderly crowd increased with their ages. Conclusion For the prevention and treatment of common diseases and latent glomerular diseases, ophthalmic examination has a good guiding significance.

目的 研究探讨重症监护病房(ICU)病原菌的分布及耐药情况,为临床合理使用抗菌药物提供科学依据。方法 回顾性分析2015年ICU住院患者送检细菌分离培养及药敏试验结果。结果 ICU共送检标本1 326份,分离出病原菌554株,其中革兰阴性病原菌462株(83.4%),革兰阳性病原菌48株(8.7%),真菌44株(7.9%)。革兰阴性杆菌前5位依次为鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌、粘质沙雷菌和大肠埃希菌,且多耐药菌株比例较高。革兰阳性病原菌以金黄色葡萄球菌为主,32株(66.7%),MRSA检出率78.3%(25/32)。结论 加强重症监护病房的细菌及药敏监测,根据病原菌药敏结果指导临床合理使用抗菌药物,控制耐药菌株的产生,预防及控制院内感染及感染暴发。

Objective To investigate the distribution characteristics and drug resistance of pathogenic bacteria in intensive care unit(ICU) and provide scientific evidence for clinically reasonable use of antibiotics. Methods Specimens from hospitalized intensive care unit patients in 2015 were obtained for routine bacterial isolation and culture. Results A total of 554 bacterial strains were isolated from 1326 specimens, in which Gram-negative bacilli accounted for 462 stains (83.4%),Gram-positive cocci accounted for 48 stains (8.7%),and fungi accounted for 44 stains (7.9%). Gram-negative bacilli of the top five were Acinetobacter baumannii,Pseudomonas aeruginosa,Klebsiella pneumoniae, Serratia marcescens and Escherichia coli,and the rate of multiple resistant bacteria was relatively high.Staphylococcus aureus were the main Gram-positive cocci, including MRSA accounted for 78.3%(25/32). Conclusion The monitoring of ICU clinical pathogens and their resistance should be strengthened. It is a great significance to use antibiotics rationally according to the results of susceptibility testing, in order to control the occurrence of resistant bacteria , prevent and control hospital infection and infection outbreak.

目的 研究音乐疗法对新生儿喂养不耐受的保护作用,以及对胃动素和胃泌素水平的影响。方法 将2013年3月—2015年6月在我院新生儿科住院治疗的40例喂养不耐受新生患儿随机分为音乐治疗组和常规治疗组,治疗干预后,比较两组的喂养不耐受情况以及GAS和MOT水平。结果 音乐治疗组腹胀缓解时间、吸吮吞咽功能建立时间、达足量喂养时间、静脉营养应用时间明显的短于常规治疗组,体重增加量明显的高于常规治疗组(P＜0.05);治疗后,音乐治疗组的GAS和MOT水平明显的高于常规治疗组(P＜0.05)。结论 音乐疗法可以促进新生儿喂养不耐受症状改善,提高患儿血清GAS和血浆MOT水平,促进其生长发育。

Objective To study music therapy for neonatal feeding intolerance protection, and the effects of levels of gastrin and motilin. Methods From March 2013 to June 2015 in newborn Department of Pediatrics in our hospital 40 cases feeding tolerance of newborns were randomly divided into music therapy group and routine treatment group, after treatment, compared feeding tolerance and GAS and MOT level in the two groups. Results Abdominal distension relieving time, sucking and swallowing function establishment time, full enteral feeding time, use of the parenteral nutrition in the music therapy group was fewer than the conventional therapy group. Weight gain was higher than that in the conventional treatment (P<0.05). After the treatment, GAS and MOT levels in the music therapy group were higher than conventional treatment group, the difference is statistical significant (P<0.05). Conclusion Music therapy may promote neonatal feeding intolerance symptoms and improve patients serum GAS and plasma MOT levels, promote their growth and development.

目的 探讨皮罗氏序列征伴先天性心脏病的临床特点。方法 我院2011年1月—2015年12月共收治141例皮罗氏序列征的患儿,将患儿分成单纯皮罗氏序列征组、皮罗氏序列征伴腭裂组及皮罗氏序列征伴听力损伤组,对3组患儿均行心电图及彩色多普勒超声心动图检查,对检查结果进行分析。结果 141例皮罗氏序列征患儿中共检出先天性心脏病19例,总发生率为13.47%,其中单纯皮罗氏序列征组患儿先天性心脏病的发生率为12.82%,伴腭裂组和伴听力损伤组患儿先天性心脏病的发生率分别为13.56%、25%。主要的先天性心脏病为:房间隔缺损(ASD)、室间隔缺损(VSD)、动脉导管未闭(PDA)、肺动脉瓣狭窄(PS)。通过统计学分析,3组患儿先天性心脏病的发生率差异无显著性。结论 先天性心脏病在皮罗氏序列征患儿中发生率较高,心电图及彩色多普勒超声心动图检查能清楚准确地诊断各类型的先天性心脏病,可用于皮罗氏序列征患儿常规检查,做出早期诊断、治疗,可以改善患儿的预后。

Objective To explore the clinical characteristics of congenital heart diseases in patients with Pierre-Robin sequence. Methods From January 2011 to December 2015, Guangzhou Women and Children's Medical Center has treated 141 patients with Pierre-Robin sequence. They were divided into 3 groups: Pierre-Robin sequence group, Pierre-Robin sequence and cleft palate group, and Pierre-Robin sequence and hearing impairment group. Electrocardiogram and colour Doppler echocardiogram was performed in each group and the results were analysed with statistics. Results 19 patients were found to have congenital heart diseases in 141 patients, the occurrence rate was 13.47%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence was 12.82%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence and cleft palate was 13.56%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence and hearing impairment was 25%. Atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA),and pulmonary valve stenosis (PS) were the most common lesions. Through statistical analysis, the occurrence rate of congenital heart diseases has no significant difference among the three groups of patients. Conclusion The occurrence rate of congenital heart diseases in patients with Pierre-Robin sequence is high. Electrocardiogram and colour Doppler echocardiogram are the useful and reliable tool in diagnosing congenital heart diseases in patients with Pierre-Robin sequence.

目的 探讨在待产孕妇中应用中医药辨证护理对促进气血虚弱型足月妊娠孕妇宫颈成熟的临产前护理策略及临床效果。方法 选取中医辨证为气血虚弱型的足月妊娠单胎头位初产妇180例,随机分为对照组即催产素组及常规护理组60例,中医药辨证护理组即在对照组的基础上入院后即给予中药口服加辨证护理60例,空白组即期待观察组及常规护理组60例。观察三组治疗前后宫颈Bishop评分,阴道及宫颈分泌物FFN(胎儿纤连蛋白)定性测定,分娩结局及对母胎的影响。结果 中医药辨证护理组在临产率、阴道分娩率及宫颈评分、FFN测定等方面较对照组及空白组均有差异,P<0.05。结论 对于气血虚弱型足月妊娠在入院后开展中医药辨证护理对临产前宫颈成熟有辅助作用,对于提高顺产率,降低高危分娩促进母儿健康有积极作用,值得推广。

Objective To explore the prenatal care strategy of applying Chinese medicine dialectical care to promoting cervical ripening of full-term pregnant women with qi-blood deficiency and its clinical effect. Methods We chose 180 first-time, full-term pregnant women with single fetus cephalic presentation who were diagnosed as with qi-blood deficiency and then randomly divided them into three groups, 60 in control group with oxytocin and usual care; 60 in group of Chinese medicine dialectical care, which provided oral use of Chinese medicine and dialectical care after those women being admitted to hospital; 60 in blank group with usual observation and care. We did Bishop assessment of neck of uterus before and after treatment in these three groups, conducted qualitative test in FFN (Fetal Fibronectin), the secreta from vagina and neck of uterus, and observed delivery outcome as well as the influence to mother and child. Results Compared with control group and blank group, the group ofChinese medicine dialectical care was outstanding in terms of labor rate, vaginal delivery rate, and FFN test(P<0.05). Conclusion Chinese medicine dialectical care boosts cervical ripening of full-term pregnant women with qi-blood deficiency. It is helpful to increase natural labor rate, reduce high-risk delivery, and promote health of mother and child. Therefore it is worth to be popularized.

目的 探讨健康成人颈段气管的体外高频超声影像特点,为开展体外超声在检测颈段气管病变应用作前期研究。方法 应用体外高频超声观察120例健康成人颈段气管结构的声像表现,并对气管环T1-T4的内外横径、气管环厚度、相邻气管环间距进行测量和统计学分析。结果 120例志愿者均获得了颈段气管前、侧壁声像图,以及气管环T1-T4内外横径、气管环厚度、相邻气管环间距测值。结论 体外高频超声可以清晰显示气管形态和细微支撑结构,并进行部分径线测量,有望成为评估颈段气管病变的一种有价值的辅助手段。

Objective We investigated features of the healthy adult cervical tracheas in order to studying cervical tracheal lesions by extracorporeal high-frequency ultrasound EHFUS. Methods EHFUS examination of the trachea was performed in 120 asymptomatic adult volunteers. We observed imaging features of the healthy adult cervical tracheas, and measured TRID, TRED, TRTh and TRAS to analysis. Results The cervical tracheal anterior and side wall ultrasonograms, and measurements were obtained in all subjects. Conclusion The cervical tracheal shape and the fine structure of support can be seen in EHFUS, and partly of diameter measurements were obtained. Thus EHFUS may be a valuable assistant method to assess cervical tracheal lesions of support structure.

目的 探讨微泡增强的超声空化增加睾丸组织的药物浓度的可行性。方法 18只雄性8月龄性成熟新西兰兔随机分为空白对照组(C)、单纯微泡组(MB)、治疗超声组(TUS)、超声联合微泡辐照组(MEUS)4组,每组各9个。MB组给予静注微泡造影剂 0.1 mL/kg ;TUS组给予超声辐照5min;MEUS组给予静注微泡造影剂0.1 mL/kg的同时超声辐照5min;每组在治疗前5min均经耳缘静脉注射2%伊文思蓝(EB)2.5 mL/kg;治疗后1 h取各组睾丸组织制备组织匀浆测量 EB 浓度。结果 MEUS组兔睾丸组织内 EB 浓度高于其他各组(P<0.05),差异有统计学意义。结论 微泡增强的超声空化可以明显提高睾丸组织内EB浓度。

Objective To investigate feasibility of microbubbles enhanced ultrasound (MEUS) on the concentration of Evans blue (EB) in rabbit,stestis. Methods Eighteen sexually mature male New Zealand rabbits were divided into four groups randomly. Pulsed ultrasound irradiation and intravenous microbubbles injection were both applied in the microbubbles enhanced ultrasound group (MEUS), pulsed ultrasound irradiation and intravenous microbubbles injection were individually applied in the therapeutic ultrasound group (TUS) and the simple microbubbles group (MB). Injection of EB was applied in each group five minutes before the treatment.Concentration of EB in testis tissue was measured homogenated. Results The concentration of Evans blue(EB) in rabbit's testis in MEUS group was statistically higher than the other groups (P<0.05). Conclusion Microbubbles enhanced ultrasound (MEUS) can increase the concentration of Evans blue (EB) in rabbit's testis.

目的 观察采用桂枝茯苓汤联合甲氨蝶呤治疗异位妊娠的效果。方法 纳入90例异位妊娠患者,随机分为3组各30例,A组服用甲氨蝶呤,B组服用桂枝茯苓汤,C组采用桂枝茯苓汤联合甲氨蝶呤治疗,观察3组的治疗效果及附件包块变化情况。结果 3组治愈率整体比较,差异有统计学意义(P<0.05)。C组的治愈率与A组、B组分别比较,差异均有统计学意义(P<0.05)。3组附件包块治疗有效率整体比较,差异有统计学意义(P<0.05)。C组的有效率与A组、B组分别比较,差异均有统计学意义(P<0.05)。结论 桂枝茯苓汤联合甲氨蝶呤治疗异位妊娠,在降低β-HCG、症状改善、缩小包块方面均有较好效果,且副反应少、经济、方便。

目的 探讨青少年过敏性鼻炎与血清维生素D水平的相关性。方法 收集2012年4月—2014年4月经本院耳鼻喉科确诊的青少年过敏性鼻炎(AR)患者368例,为实验组;另选择同期本院健康体检者370例,为对照组。分别使用串联质谱仪检测其血清总维生素D、维生素D₂及维生素D₃浓度。结果 实验组中血清总维生素D、维生素D₂及维生的素D₃的检测结果分别为:20.92±3.35 ng/ml、3.64±0.82 ng/ml、18.83±3.62 ng/ml;对照组中血清总维生素D、维生素D₂及维生的素D₃的检测结果分别为:31.45±2.86 ng/ml、3.85±0.58 ng/ml、28.97±3.18 ng/ml;检测结果显示实验组与对照组总维生素D及维生素D₃水平均存在差异(P＜0.05),具有统计学意义,维生素D₂水平无差异(P＞0.05)。结论 青少年过敏性鼻炎血清维生素D水平比正常人群偏低,且以维生素D₃水平偏低为主,为临床诊治过敏性鼻炎患者提供重要依据。