目的 对比内镜逆行阑尾炎治疗术(ERAT)与腹腔镜阑尾切除术(LA)治疗急性化脓性阑尾炎(ASA)的效果。方法 按随机数字表法将2022年7月-2025年12月本院收治的106例SAS患者分为对照组(LA治疗)及观察组(ERAT治疗),各53例。比较两组围手术期指标、术后恢复指标、炎症因子水平[C反应蛋白(CRP)、白介素-6(IL-6)、降钙素原(PCT)]、疼痛介质水平[P物质(SP)、前列腺素E2(PGE2)、5-羟色胺(5-HT)]、免疫功能、胃肠激素[胃泌素(GAS)、血管活性肠肽(VIP)、胃动素(MTL)]、并发症、复发率。结果 观察组较对照组术中出血量更少,手术、住院时间与肛门排气、首次下床活动、体温复常及术后进食时间更短,并发症发生率更低;术后48h的CRP、IL-6、PCT、SP、PGE2、5-HT及VIP水平更低,CD3+、CD4+、CD4+/CD8+与GAS、MTL水平更高,有统计学差异(P<0.05);术后3个月内,两组均无1例复发。结论 与LA治疗ASA相比,ERAT具有创伤小、恢复快、炎症反应轻、并发症少等优势,且对免疫功能、胃肠功能影响小等优势,值得临床借鉴。
目的 分析经腹部浅表超声检查对急性阑尾炎患者检出率的影响。方法 选取濮阳市人民医院2018年12月—2020年6月疑似急性阑尾炎患者146例,均行腹部超声、浅表超声检查,以术后诊断为金标准,比较腹部、浅表超声单独及联合诊断效能、对不同类型急性阑尾炎检出率,分析不同类型急性阑尾炎影像学结果。结果 以术后诊断为金标准,146例疑似急性阑尾炎患者中阳性87例,阴性59例;腹部超声检出阳性80例,阴性66例;浅表超声检出阳性91例,阴性55例;腹部浅表超声检出阳性86例,阴性60例;腹部浅表超声诊断急性阑尾炎准确度99.32%(145/146)、灵敏度98.85%(86/87)、特异度100.00%(59/59)高于腹部超声[70.55%(103/146)、71.26%(62/87)、69.49%(41/59)]及浅表超声[69.86%(102/146)、77.01%(67/87)、59.32%(35/59)]单独诊断,漏诊率1.15%(1/87)、误诊率0.00%(0/59)低于腹部超声[28.74%(25/87)、30.51%(18/59)]及浅表超声[22.99%(20/87)、40.68%(24/59)]单独诊断(P<0.05);腹部浅表超声对不同类型急性阑尾炎总检出率高于单独检查(P<0.05)。结论 腹部浅表超声应用于急性阑尾炎诊断,可提高诊断准确度、灵敏度、特异度,降低漏诊率及误诊率,对不同类型急性阑尾炎检出率提高有积极作用,可收集患者详细声像信息,为临床治疗方案制定提供方向。
目的 探究与分析化脓性阑尾炎抗生素治疗后不同时机腹腔镜阑尾切除术的疗效及预后。方法 研究于2019年1月—2021年1月进行,我院收治的96例化脓性阑尾炎患者为此研究的参与对象,接受抗生素治疗≤72 h后手术的患者为观察组(n=38),>72 h的患者为对照组(n=38)。对比2组患者的指标。结果 2组的手术时间等相较均无差异(P>0.05);观察组的住院时间及住院费用均短于或少于对照组(P<0.05)。观察组术前中性粒细胞比例及白细胞计数高于对照组(P<0.05);术后2组患者组间无差异(P>0.05)。观察组的腹腔渗液阳性率低于对照组(P<0.05)。2组并发症发生率比较,组间无差异(P<0.05)。结论 化脓性阑尾炎患者经抗生素治疗后续尽早接受手术治疗。
目的 探讨急性阑尾炎(acute appendicitis, AA)及急性感染性肠炎(acute infectious enteritis, AIE)患儿的阑尾高频超声影像特点及其显像敏感性。方法 回顾性分析临床确诊为急性阑尾炎患儿120例,急性感染性肠炎患儿160例,并对其行高频超声检查,另设120例正常儿童为对照组。分析高频超声阑尾显示率,阑尾外径,阑尾周围系膜炎性变化以及阑尾的位置等情况。结果 AA组、AIE组、对照组阑尾的显示率分别为96.7%、80.6%、68.3%,差异有统计学意义(P<0.05)。三组超声显示的阑尾外径分别为(8.5±2.2)mm、(4.3±0.8)mm、(3.5±0.7)mm,相互间差异亦均有统计学意义(P<0.05)。AA组所有的阑尾周围系膜炎症改变均可探及,但AIE组的阑尾周围系膜无变化。结论 小儿急性阑尾炎高频超声显像敏感性高,旨在为临床对AA早期诊断、早期治疗提供较准确全面的影像学依据。
Objective Use high-frequency ultrasound to determine the frequency of visualization and image feature of the appendix in children with acute appendicitis (acute appendicitis, AA) and with acute infectious enteritis (acute infectious enteritis, AIE). Methods The ultrasonic features of 120 children with AA, 160 children with AIE, and 120 randomly selected asymptomatic children were analyzed retrospectively. And their visualization rate, outer appendiceal diameter, presence or absence of inflamed periphery appendiceal mesenterium, and location of the appendix were recorded. Results The visualization rates of the appendix were 96.7%, 80.6%, and 68.3% for AA groups, AIE groups, and the control, respectively(P<0.05). The outer appendiceal diameters for the 3 groups were (8.5±2.2)mm, (4.3±0.8)mm, and (3.5±0.7)mm. Difference among the 3 groups was statistically significant also. Periphery appendiceal inflamed mesenterium was detected in all AA cases, but in none of the AIE cases. Conclusion High ultrasound imaging sensitivity of puerile acute appendicitis provided relatively accurate comprehensive imaging basis for clinical early diagnosis and early treatment.
目的 回顾分析高原地区儿童阑尾炎术后早期炎性肠梗阻的临床特征,总结治疗经验。方法 回顾分析青海省妇女儿童医院2019—2023年收治的49例儿童阑尾炎术后早期炎性肠梗阻病例资料。结果 纳入研究的49例患儿,阑尾炎发病时间3~8 d,平均(5.38±1.25)d,术后出现肠梗阻时间3~11 d,平均时间(4.81±1.70)d,其中48例经过保守治疗后梗阻解除,恢复排气、排便,肠功能恢复时间4~13 d,平均(5.93±2.49)d,1例经积极保守治疗后病情进展,最终经手术治愈。49例患儿均顺利治愈出院,住院时间10~26 d,平均(15.69±3.79)d。术后随访1~2年,患儿饮食、排便均无异常。结论 高原地区儿童阑尾炎术后早期粘连性肠梗阻预防是关键,采取保守治疗同样可获得较高的治愈率,若保守治疗无效或病情进展应及时积极采取手术治疗。
Objective To review the clinical characteristics of early postoperative inflammatory small bowel obstruction(EPISBO) in children with appendicitis in plateau area and summarize the treatment experience.Methods The data of 49 cases of appendicitis EPISBO in children admitted to Qinghai Women and Children’s Hospital from 2019 to 2023 were retrospectively analyzed.Results The onset time of appendicitis was 3-8 days,with an average of(5.38±1.25)days,and the time of intestinal obstruction was 3-11 days after surgery,with an average of(4.81±1.70)days.After conservative treatment,48 cases were relieved of obstruction,resumed exhaust and defecation,and intestinal function recovered in 4-13 day,average(5.93±2.49)d,1 case had progression after conservative treatment,and was cured by surgery.All the 49 children were successfully cured and discharged.The length of hospital stay was 10-26 days,with an average of(15.69±3.79)days.Postoperative follow-up of 1 to 2 years showed normal eating and bowel movements.Conclusions The prevention of EPISBO in children with appendicitis in plateau area is the key.Conservative treatment can also achieve a higher cure rate.If conservative treatment is ineffective or the disease progresses,timely surgical treatment should be provided.