目的 对比分析甲氨蝶呤(methorexate,MTX)联合超声监视下清宫与甲氨蝶呤、子宫动脉栓塞术(uterine artery embolization,UAE)联合清宫治疗停经7周内Ⅱ-Ⅲ型剖宫产瘢痕妊娠(ceasarean scarpregnancy,CSP)的效果。方法 回顾性分析我院自2016年1月—2017年12月收治的停经7周内Ⅱ-Ⅲ型CSP患者的临床资料,按随机、平衡、对照原则分别筛选69例MTX+清宫治疗患者作为A组,68例MTX+UAE+清宫治疗患者作为B组,对比两组治疗成功率、一般治疗情况及术后并发症发生率,并统计两组月经周期恢复时间、血β-hCG恢复至正常时间、疤痕妊娠病灶消失时间。结果 两组术后恢复良好,术中、术后均未发生不可控制宫腔出血现象,胎囊组织均全部清出,A组术中出血量、子宫切除发生率、发热、术后盆腹腔疼痛及肝功能损伤发生率均低于B组,术后第1天血β-hCG下降超过50%及治疗成功率、住院时间均高于B组,且该组月经周期恢复时间、血β-hCG恢复至正常时间、疤痕妊娠病灶消失时间亦较B组短(P﹤0.05)。结论 于停经7周内Ⅱ-Ⅲ型CSP患者而言,行MTX+清宫治疗或可在不增加出血风险基础上避免UAE相关并发症及副反应。
Objective To comparatively analyze the effects of methotrexate (MTX) combined with uterine curettage under ultrasonic monitoring and MTX, uterine artery embolization (UAE) combined with uterine curettage in the treatment of cesarean scar pregnancy (CSP) within 7 weeks of menopause. Methods The clinical data of patients with type Ⅱ-Ⅲ CSP within 7 weeks of menopause who were admitted to the hospital from January 2016 to December 2017 were analyzed retrospectively. Another 69 cases treated with MTX combined with uterine curettage were selected as group A and 68 cases treated with MTX+UAE+uterine curettage were selected as group B. The success rate of treatment, general situation of treatment and the incidence of adverse reactions were compared between the two groups. The time of menstrual recovery, the recovery time of blood β-hCG and the disappearance time of scar pregnancy lesions were statistically analyzed. Results The two groups recovered well after operation, and there was no uncontrollable uterine bleeding. All fetal sac tissues were cleared. The intraoperative blood loss, hysterectomy rate, incidence rates of fever, postoperative abdominopelvic pain and liver function injury in group A were less/lower than those in group B, The rate of blood β-hCG decreasing more than 50% on the 1st day after operation, the success rate of treatment and hospitalization time of groups A were higher/longer than those of group B, while the time of menstrual recovery, recovery time of blood β-hCG and the disappearance time of scar pregnancy lesions was shorter than that of group B(P<0.05). Conclusion MTX combined with uterine curettage may avoid complications and side effects of UAE in patients with type Ⅱ-Ⅲ CSP within 7 weeks of menopause, without increasing the risk of bleeding.
目的 对比热敏灸联合“合谷刺法”与温灸针“合谷刺法”治疗肩周炎的疗效。方法 2015年7月—2017年1月,筛选康复科收治的慢性肩周炎患者120例,按照随机数字表达法分组,对照1组、对照组2组、观察组各入选40例。对照1组采取温针灸“合谷刺法”,对照2组采取传统取穴针刺疗法,观察组热敏灸联合“合谷刺法”。对比3组疗效,治疗前后肩关节功能ASES量表(American Shoulder and Elbow Surgeons shoulder index)、VAS肩关节疼痛评分、肩关节活动度。结果 3组均未见退出例。观察组愈显率82.5%高于对照1组50.0%、对照组2组55.0%,差异有统计学意义(P<0.05),观察组整体疗效与对照2组差异无统计学意义(P>0.05)。治疗后,观察组、对照1组、对照2组VAS肩关节疼痛评分低于治疗前,观察组治疗后差值高于对照1组、对照2组,ASES评分高于治疗前,观察组治疗前后差值高于对照1组、对照2组,差异有统计学意义(P<0.05)。治疗后,观察组、对照1组、对照2组前屈上举角度、外展上举与后伸角度、水平内收外展角度高于治疗前,观察组高于对照1组、对照2组,差异有统计学意义(P<0.05)。结论 热敏灸联合“合谷刺法”与温灸针“合谷刺法”在治疗肩周炎疗效肯定,但前者减轻疼痛、改善功能方面有明显的优势。
目的 探讨优质护理对于提高白内障手术患者术后恢复的影响。方法 选取本院自2014年1月—2014年6月收治的56例实施白内障手术的患者,将患者平均分配为对照组和实验组,对照组实行常规护理服务,观察组实施优质护理服务,建立完善的护理人员工作机制,提高护理人员素质;加强对患者的健康教育和心理护理,及时给患者进行检查。统计两组患者的治疗效果,分析优质护理服务的效果。结果 在术后接受优质护理服务的实验组患者的恢复效果好于对照组患者,术后的不良事件发生率较对照组低,患者的疼痛程度低,二组数据差异具有统计学意义。结论 给白内障术后的患者以优质护理服务能提高护理质量,缩短患者恢复时间,提高患者恢复效果。
目的 探讨、对比休克指数(SI)与血乳酸水平预测院前创伤性休克患者预后中的应用。方法 于2020年12月—2023年12月收治80例创伤性休克患者,均接受SI、乳酸水平的监测。结合监测的结果进行分组:乳酸正常组:乳酸水平在2 mmol/L以下,升高组:2 mmol/L以上;SI正常组:SI在0.9以下,升高组:SI在0.9以上。观察、记录患者入院7 d后的序贯性器官功能衰竭评分(SOFA),对多器官功能障碍综合征(MODS)情况进行评估。同时观察、记录机械通气、血管活性药物的使用和住院等情况。结果 乳酸水平升高组60例,正常组20组;SI升高组58例,正常组22例,女性乳酸水平、SI,与男性比较差异无统计学意义(P>0.05)。是否发生多器官功能障碍者的年龄、性别、SI指数比较差异无统计学意义(P>0.05);格拉斯哥昏迷评分(GCS)评分[(4.22±1.53)分 vs (9.46±3.82)分,t=7.816,P<0.001]、住院时间[(23.34±5.71)d vs (12.26±2.11)d,t=11.830,P<0.001]、基础乳酸值[(4.75±2.36)mmol/L vs (2.04±1.11)mmol/L,t=6.721,P<0.001]与发生MODS在组间对比差异有统计学意义。SI升高组的容量复苏收缩压>80 mmHg(%)有27例,与乳酸水平升高组比较差异有统计学意义(P<0.05)(46.55% vs 18.18%,χ 2 =12.237,P<0.001)。乳酸水平升高组中,11例患者接受机械通气,乳酸水平均升高(P<0.05);9例患者使用血管活性药物,乳酸水平均升高,比较差异无统计学意义(P>0.05);38例住院患者,24例乳酸水平升高(P<0.05)。13例患者接受机械通气,12例SI升高,比较差异无统计学意义(P>0.05);11例患者接受血管活性物治疗,8例SI升高,比较差异无统计学意义(P>0.05);39例患者住院,SI升高22例,比较差异有统计学意义(P<0.05)。结论 针对重症的创伤性休克患者,当血乳酸水平升高时会大大增加MODS发生的概率,乳酸水平在对重症创伤性休克患者预后进行预测时,应用价值更高。
Objective To explore and compare the application of shock index(SI)and blood lactic acid level in predicting the prognosis of patients with pre-hospital traumatic shock.Methods From December 2020 to December 2023,80 patients with traumatic shock were enrolled,and their SI and levels of lactic acid were monitored.Patients were grouped according to the monitoring results:normal group:lactic acid level below 2 mmol/L,increased group:above 2 mmol/L;normal group:SI below 0.9,and increased group:SI above 0.9.The sequential organ failure score(SOFA)was observed and recorded 7 days after hospitalization,and the situation of multiple organ dysfunction syndrome(MODS)was evaluated.At the same time,mechanical ventilation,the use of vasoactive substances and hospitalization were observed and recorded.Results There were 60 cases in the group with increased lactic acid level and 20 cases in the normal group.There were 58 cases of increased SI and 22 cases of normal.The lactic acid level and SI index in women were higher than those in men,with no difference(P>0.05).There were no differences in age,sex,SI index and the incidence of MODS(P>0.05).GCS score(4.22±1.53 vs 9.46±3.82),hospitalization days(23.34±5.71 vs 12.26±2.11)d,basal lactate value(4.75±2.36 vs 2.04±1.11)mmol L-1 were significantly different from those of MODS(t=11.830,P<0.001;t=6.721,P<0.001,P<0.05).There were 27 cases with volume resuscitation systolic blood pressure > 80 mmhg(%)in the group with increased SI,which was different from that of SI and lactic acid(46.55% vs18.18%,χ 2 =12.237,P<0.001;P<0.05).Lactic acid increased group:11 patients received mechanical ventilation,and the lactic acid levels of all 11 patients increased(P<0.05).Nine patients used vasoactive substances,and their lactic acid levels all increased,with no significant difference(P>0.05).Of the 38 inpatients,24 cases had elevated lactic acid levels(P<0.05).Thirteen patients received mechanical ventilation,and 12 patients had elevated SI,with no statistical significance(P>0.05).Eleven patients were treated with vasoactive agents,and 8 patients had increased SI,with no difference(P>0.05).Among the 39 patients hospitalized,22 cases had increased SI,and the difference was statistically significant(P<0.05).Conclusions For patients with severe traumatic shock,when the blood lactic acid level increases,the probability of MODS will be greatly increased.Compared with SI index,lactic acid level has higher application value in predicting the prognosis of patients with severe traumatic shock.