广州医药 ›› 2017, Vol. 48 ›› Issue (3): 82-85.DOI: 10.3969/j.issn.1000-8535.2017.03.021

• 论著 • 上一篇    下一篇

绝经后女性行激素替代及护理综合疗法对干眼症的疗效观察

骆丽丝, 丁小珍, 金敏, 杨为中   

  1. 广州市第一人民医院(广州 510180)
  • 收稿日期:2017-01-09 发布日期:2021-12-01

Effect of hormone replacement therapy and comprehensive nursing care on xerophthalmia in postmenopausal women

LUO Lisi, DING Xiaozhen, JIN Min, YANG Weizhong   

  1. Guangzhou First People's Hospital, Guangzhou 510180
  • Received:2017-01-09 Published:2021-12-01

摘要: 目的 观察尝试采用激素替代疗法(hormonereplace menttherapy,HRT)治疗更年期疾病的干眼症的临床疗效。方法 将80例(160眼)干眼症患者随机分成2组,治疗组40例(80眼)在滴人工泪液的基础上采用激素替代疗法(HRT)口服治疗。对照组40例(80眼)单纯采用人工泪液滴眼液滴双眼。两组同时给予综合护理。3个月后观察疗效。结果 治疗组总有效率82.5%,对照组总有效率60%,两组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论 在人工泪液滴眼液滴双眼的基础上尝试采用激素替代疗法(HRT)治疗更年期疾病的干眼症患者,效果优于单纯应用人工泪液点眼。

关键词: 干眼症, 更年期, 激素, 护理

Abstract: Objective To investigate the role of hormone replace menttherapy (HRT) in treating xerophthalmia among patients with climacteric disease. Methods Eighty xerophthalmia patients (160 eyes) were randomly divided into two groups. Forty patients in the treatment group (80 eyes) were treated using combined HRT and artificial drops. Forty patients in the control group (80 eyes) were treated using artificial drops alone. All patients were provided comprehensive nursing. The evaluation of clinical effects was performed after 3 months of treatment. Results The total effective rate of both groups was 82.5% in the treatment group and 60% in the control group, respectively (P<0.05). Conclusion Combined HRT and artificial drops is more effective in treating climacteric disease-related xerophthalmia than using artificial drops only.

Key words: Xerophthalmia, Climacteric disease, Hormone, Nursing