目的 比较白内障超声乳化吸除术(Phaco)+房角分离术与Phaco+小梁切除术治疗急性原发性闭角型青光眼(APACG)合并白内障的临床价值。方法 回顾性分析2022年1月至2025年1月我院200例APACG合并白内障患者临床资料,根据手术方式分为小梁切除组(Phaco+小梁切除术)与房角分离组(Phaco+房角分离术),每组100例(200眼)。比较两组眼压、视力[最佳矫正视力(BCVA)]、中央前房深度、视盘血流密度[整体视盘血流密度(wiVD)、视盘内血流密度(diVD)]、生活质量[视功能相关生活质量量表-25(NEI-VFQ-25)]及并发症情况。结论 术后1周、1个月、3个月,房角分离组眼压低于小梁切除组,BCVA、中央前房深度大于小梁切除组,wiVD、diVD高于小梁切除组(P<0.05);术后1个月,房角分离组NEI-VFQ-25评分高于小梁切除组(P<0.05),术后3月两组NEI-VFQ-25评分比较无显著差异(P>0.05);房角分离组并发症总发生率(6.50%)低于小梁切除组(13.00%)(P<0.05)。结论 与Phaco+小梁切除术相比,Phaco+房角分离术治疗APACG合并白内障患者能有效控制眼压,增加前房深度,改善视盘血流循环,恢复患者视力,提高生活质量,减少并发症发生率。
Objective To compare the clinical efficacy of phacoemulsification (Phaco) combined with goniosynechialysis and phacoemulsification combined with trabeculectomy in the treatment of acute primary angle-closure glaucoma (APACG) complicated with cataract. Methods The clinical data of 200 patients with APACG complicated with cataract treated in our hospital from January 2022 to January 2025 were retrospectively analyzed. According to surgical procedures, the patients were divided into trabeculectomy group (Phaco combined with trabeculectomy) and goniosynechialysis group (Phaco combined with goniosynechialysis), with 100 patients (200 eyes) in each group. Intraocular pressure, visual acuity [best corrected visual acuity (BCVA)], central anterior chamber depth, optic disc vessel density [whole-image optic disc vessel density (wiVD), disc-inside vessel density (diVD)], quality of life [25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25)] and complications were compared between the two groups. Results At 1 week, 1 month and 3 months after surgery, the goniosynechialysis group had lower intraocular pressure, better BCVA, deeper central anterior chamber depth, and higher wiVD and diVD than the trabeculectomy group (P<0.05). One month postoperatively, the NEI-VFQ-25 score of the goniosynechialysis group was significantly higher than that of the trabeculectomy group (P<0.05), while no significant difference was observed between the two groups at 3 months after surgery (P>0.05). The overall incidence of complications in the goniosynechialysis group was 6.50%, which was lower than 13.00% in the trabeculectomy group (P<0.05). Conclusion Compared with phacoemulsification combined with trabeculectomy, phacoemulsification combined with goniosynechialysis can effectively control intraocular pressure, increase anterior chamber depth, improve optic disc blood circulation, restore visual acuity, enhance quality of life and reduce the incidence of complications in patients with APACG complicated with cataract.
目的 基于最佳矫正视力(BCVA)、角膜水肿程度对比改良与常规小梁切除术治疗急性闭角型青光眼(AACG)的疗效。方法 回顾性收集2021年12月—2023年6月期间信阳爱尔眼科医院收治的112例AACG患者作为研究对象,依据1∶1匹配原则,将接受常规小梁切除术的56例患者作为对照组,接受改良小梁切除术的56例患者作为观察组,统计两组围术期BCVA、眼压、术后浅前房形成状况、角膜水肿程度以及并发症状况。结果 术后3个月,观察组视力为(0.63±0.04)logMAR,高于对照组(0.50±0.03)logMAR,眼压为(16.22±2.28)mmHg,低于对照组(19.95±2.31)mmHg(t=19.457、8.600,均P<0.05);观察组浅前房发生率为8.93%,低于对照组的26.79%(χ2=6.087,P=0.014);观察组角膜水肿状况优于对照组(Z=2.737,P=0.006);观察组脉络膜脱离率、滤道阻塞率、前房积血率、虹膜炎症率依次为1.79%、5.36%、16.07%、10.71%,均低于对照组17.86%、23.21%、32.14%、35.71%(χ2=8.166、7.292、3.953、9.818,均P<0.05)。结论 较常规小梁切除术,改良小梁切除术治疗AACG患者,有助于改善视力、降低眼压、减轻角膜水肿、减少浅前房发生,且安全性较高。
Objective To compare the efficacy of modified and conventional trabeculectomy in the treatment of acute angle-closure glaucoma(AACG)based on best-corrected visual acuity(BCVA)and degree of corneal edema.Methods A total of 112 patients with AACG admitted to the hospital during December 2021 to June 2023 were retrospectively selected as study objects. According to the 1∶1 matching principle,56 patients receiving conventional trabeculectomy were selected as control group,and 56 patients receiving modified trabeculectomy were selected as observation group.Perioperative BCVA,intraocular pressure,postoperative shallow anterior chamber formation,degree of corneal edema and complications were analyzed.Results At three months postoperatively,visual acuity in the observation group was(0.63±0.04)logMAR,which was higher than that in the control group(0.50±0.03)logMAR,and intraocular pressure was(16.22±2.28)mmHg,which was lower than that in the control group(19.95±2.31)mmHg(t=19.457,8.600,P<0.05);the incidence of shallow anterior chamber in the observation group was 8.93%,which was lower than that of the control group(26.79%)(χ2=6.087,P=0.014);the corneal edema status in the observation group was better than that of the control group(Z=2.737,P=0.006);the rates of choroidal detachment,filtering channel obstruction,hyphema,and iris inflammation in the observation group were 1.79%,5.36%,16.07%,and 10.71%,respectively,which were lower than those of the control group(17.86%,23.21%,32.14%,and 35.71%)(χ2=8.166,7.292,3.953,and 9.818,P<0.05).Conclusions Compared with conventional trabeculectomy,modified trabeculectomy can improve visual acuity,reduce intraocular pressure,relieve corneal edema,and reduce the occurrence of shallow anterior chamber in patients with AACG,with higher safety.
目的 基于最佳矫正视力(BCVA)、角膜水肿程度对比改良与常规小梁切除术治疗急性闭角型青光眼(AACG)的疗效。方法 回顾性收集2021年12月—2023年6月期间信阳爱尔眼科医院收治的112例AACG患者作为研究对象,依据1∶1匹配原则,将接受常规小梁切除术的56例患者作为对照组,接受改良小梁切除术的56例患者作为观察组,统计两组围术期BCVA、眼压、术后浅前房形成状况、角膜水肿程度以及并发症状况。结果 术后3个月,观察组视力为(0.63±0.04)logMAR,高于对照组(0.50±0.03)logMAR,眼压为(16.22±2.28)mmHg,低于对照组(19.95±2.31)mmHg(t=19.457、8.600,均P<0.05);观察组浅前房发生率为8.93%,低于对照组的26.79%(χ 2 =6.087,P=0.014);观察组角膜水肿状况优于对照组(Z=2.737,P=0.006);观察组脉络膜脱离率、滤道阻塞率、前房积血率、虹膜炎症率依次为1.79%、5.36%、16.07%、10.71%,均低于对照组17.86%、23.21%、32.14%、35.71%(χ 2 =8.166、7.292、3.953、9.818,均P<0.05)。结论 较常规小梁切除术,改良小梁切除术治疗AACG患者,有助于改善视力、降低眼压、减轻角膜水肿、减少浅前房发生,且安全性较高。
Objective To compare the efficacy of modified and conventional trabeculectomy in the treatment of acute angle-closure glaucoma(AACG)based on best-corrected visual acuity(BCVA)and degree of corneal edema.Methods A total of 112 patients with AACG admitted to the hospital during December 2021 to June 2023 were retrospectively selected as study objects.According to the 1∶1 matching principle,56 patients receiving conventional trabeculectomy were selected as control group,and 56 patients receiving modified trabeculectomy were selected as observation group.Perioperative BCVA,intraocular pressure,postoperative shallow anterior chamber formation,degree of corneal edema and complications were analyzed.Results At three months postoperatively,visual acuity in the observation group was(0.63±0.04)logMAR,which was higher than that in the control group(0.50±0.03)logMAR,and intraocular pressure was(16.22±2.28)mmHg,which was lower than that in the control group(19.95±2.31)mmHg(t=19.457,8.600,P<0.05);the incidence of shallow anterior chamber in the observation group was 8.93%,which was lower than that of the control group(26.79%)(χ 2 =6.087,P=0.014);the corneal edema status in the observation group was better than that of the control group(Z=2.737,P=0.006);the rates of choroidal detachment,filtering channel obstruction,hyphema,and iris inflammation in the observation group were 1.79%,5.36%,16.07%,and 10.71%,respectively,which were lower than those of the control group(17.86%,23.21%,32.14%,and 35.71%)(χ 2 =8.166,7.292,3.953,and 9.818,P<0.05).Conclusions Compared with conventional trabeculectomy,modified trabeculectomy can improve visual acuity,reduce intraocular pressure,relieve corneal edema,and reduce the occurrence of shallow anterior chamber in patients with AACG,with higher safety.