目的 应用 Python语言对《圣济总录》中腰痛病篇中的中药进行用药规律分析,提取腰痛病治疗方法及用药特色指导临床腰痛病治疗思路。方法 运用 Python语言中的语言提取对《圣济总录》中腰痛篇章中的所有中药方剂识别,提取方剂组成,统计并分析方剂中中药的规律并将其结果可视化呈现。结果 最终共纳入62首方剂,包含药物86味。其中使用频次≥7次、频率≥1.6%的药物共20味,频次频率最高的为桂枝;所用中药四气以温性为主,占56.74%;五味以辛、甘、苦为主,共约占90%,归经以肝肾经为主;药物功效以补虚类为主,占27.13%;关联规则分析显示提升度最高的组合为麻黄-独活,置信度最高的组合为巴戟天-牛膝、牵牛子-牛膝,支持度最高的组合为川芎-当归、川芎-杜仲;通过聚类分析得到3个聚类结果。结论 《圣济总录》治疗腰痛病方面善用通法和补法,强调活血通络,补益肝肾,尤擅长治疗肝肾亏虚或风寒所客等腰痛病证。
Objective Python language was used to analyze the rules of traditional Chinese medicine in the chapter of low back pain in Shengji Zonglu,and to extract the treatment methods and medication characteristics of low back pain to guide the clinical treatment of low back pain.Methods The language extraction in Python language was used to identify all the Chinese medicine prescriptions in the chapter of low back pain in Shengji Zonglu,extract the composition of the prescription,and analyze the rules of Chinese medicine in the prescription to visually present the results.Results A total of 62 prescriptions were included,including 86 drugs.Among them,with there were 20 kinds of drugs,the frequency of use ≥7 times,the frequency ≥1.6%,and cmnamomi Mmulus highest frequency.Four gas used in traditional Chinese medicine is given priority to with warm,accounted for 56.74%.The five flavors were mainly pungent,sweet and bitter,accounting for about 90%,and the liver and kidney meridians were the main meridians.The drug efficacy was mainly deficiency tonic,accounting for 27.13%.The association rule analysis showed that the combination with the highest improvement was Ephedrae Herba- Angelicae Pubescentis Radix,the combination with the highest confidence was Morindae Officinalis Radix- Achyranthis Bidentatae Radix,Pharbitidis Semen- Achyranthis Bidentatae Radix.and the combination with the highest support was Chuanxiong Rhizoma- Angelicae Sinensis Radix,Chuanxiong Rhizoma- Eucommiae Cortex.Three clustering result is obtained by cluster analysis.Conclusions In the treatment of low back pain,Shengji Zonglu is good at using both blocking methods and reinforcing methods,emphasizing circulating blood and unblocking meridians supplementing liver and kidney,especially in the treatment of low back pain syndrome caused by liver and kidney deficiency or wind and cold.
目的 研究慢性非特异性腰痛患者腰椎正侧位X线中腰椎侧弯、L1-5棘突偏歪和椎体滑脱情况,总结规律,为慢性非特异性腰痛患者治疗提供依据。方法 选取164例慢性非特异性腰痛患者,观察并记录每例患者腰椎正侧位X线中腰椎侧弯、L1~L5棘突偏歪和椎体滑脱情况。用统计学软件分析腰椎侧弯、棘突偏歪和椎体滑脱情况。结果 共有59例发生腰椎侧弯,占35.98%,其中Cobb角5°~10 °有47例,占28.66%;Cobb角>10°有12例,占7.32%。腰椎侧弯发病以L4为下端椎为主。以L3为下端椎有12例患者,占20.34%;以L4为下端椎有37例患者,占62.71%;以L5为发椎有10例患者,占16.95%。共119例发生棘突偏歪,占总例数的72.56%。L5棘突偏歪最常见,发生率为57.93%;L4次之,发生率为48.17%。L5棘突偏歪率与L1~L3棘突偏歪率比较差异均有统计学意义(χ2分别为14.580,11.771,7.484,P分别为<0.001,0.001,0.006),但与L4棘突偏歪率比较差异无统计学意义(χ2=3.124,P=0.077)。共30例患者存在椎体滑脱,占18.29%。L5最常发生滑脱,发生率为8.54%;L4次之,发生率为7.93%。L4与L5椎体滑脱率比较差异无统计学意义(χ2=0.040,P=0.841);L4分别与L1,L2,L3以及L5分别与L1,L2,L3椎体滑脱率差异均有统计学意义(L5与L1、L2、L3:χ2分别为14.580、11.771、7.484,P分别为<0.001、<0.001、<0.006;L4与L1、L2、L3:χ2分别为13.495、10.712、6.550,P分别为<0.001、<0.001、<0.010)。结论 慢性非特异性腰痛患者较常发生腰椎侧弯,侧弯以L4为下端椎为主;慢性非特异性腰痛患者较常发生棘突偏歪,L5棘突偏歪最常见,L4次之;L5和L4是慢性非特异性腰痛患者最常发生滑脱的椎体。在治疗慢性非特异性腰痛患者时,与L5和L4相关的肌肉、筋膜等软组织损伤以及关节退行性变或紊乱应引起重点关注。
Objective To study the lumbar scoliosis,L1-5 spinous process deviation and spondylolisthesis in spine X-ray of patients with chronic non-specific low back pain(CNLBP),and summarizing the existing rules,so as to provide imaging theoretical support for the treatment of CNLBP.Methods A total of 164 patients with CNLBP were selected.The lumbar scoliosis,L1-5 spinous process deviation and spondylolisthesis were observed and recorded in the anteroposterior and lateral X-ray films of each patient.The lumbar scoliosis,spinous process deviation and spondylolisthesis were statistically analyzed by statistical software.Results A total of 59 people had lumbar scoliosis,accounting for 35.98%.There were 47 patients with 5°-10°Cobb angle,accounting for 28.66%.There were 12 patients with Cobb angle >10°,accounting for 7.32%.L4 was the main lower apical vertebra of lumbar scoliosis.There were 12 patients with L3 as the lower apical vertebra,accounting for 20.34%;37 patients with L4 as the lower apical vertebra,accounting for 62.71%;10 patients with L5 as the lower apical vertebra,accounting for 16.95%.A total of 119 people appeared spinous process deviation,accounting for 72.56%.L5 spinous process deviation was the most common,with proportion of 57.93%,and L4 was the second,with proportion of 48.17%.The results of chi-square test showed that there were significant differences between L5 and L1-L3 spinous process deviation(χ2 were 14.580,11.771,7.484,and P values were <0.001,0.001,0.006 respectively),but no significant difference between L5 and L4 spinous process(χ2=3.124,P=0.077).A total of 30 patients had spondylolisthesis,accounting for 18.29%.L5 was the most common of spondylolisthesis,with an occurrence rate of 8.54%.L4 was the second,with an occurrence rate of 7.93%.There was no significant difference in spondylolisthesis rate between L4 and L5(χ2=0.040,P=0.841).The spondylolisthesis rates of L4 and L5 were significantly different from those of L1,L2 and L3(L5 and L1,L2,L3:χ2 were 14.580,11.771,7.484,and P values were <0.001,0.001,0.006 respectively;L4 and L1,L2,L3:χ2 was 13.495,10.712,6.550,P values was <0.001,0.001,0.010 respectively).Conclusions Lumbar scoliosis is more common in patients with CNLBP,and L4 is the main lower apical vertebra of lumbar scoliosis.Patients with CNLBP often have spinous process deviation,and the most common is L5 spinous process deviation,followed by L4.L5 and L4 are the most common vertebrae with spondylolisthesis in patients with CNLBP.The soft injury and joint degeneration or disorder related to L5 and L4 should be paid more attention in the treatment of patients with CNLBP.
目的 探讨中药竹罐结合体感音乐疗法在筋伤腰痛患者中的应用效果。方法 将128例患者按入院顺序分为实验组(68例)和对照组(60例),对照组采用中药竹罐疗法,实验组采用中药竹罐结合体感音乐疗法,4周后对两组患者的疗效、VAS 评分及满意度进行测评。结果 治疗后实验组患者疗效优于对照组(P<0.01);治疗后实验组、对照组VAS 评分较治疗前降低,但实验组VAS 评分下降更明显(P<0.01);治疗后实验组、对照组对治疗效果满意度较治疗前提高,而实验组对治疗效果满意度更高(P<0.01)。结论 筋伤腰痛患者采取中药竹罐结合体感音乐疗法能起到缓解肌肉痉挛,身心放松,活血化瘀,温筋祛寒的作用。
Objective To explore the application effect of traditional Chinese medicine bamboo jar combined with somatosensory music in patients with tendon injury and low back pain. Methods 128 patients were divided into experimental group (68 cases) and control group (60 cases) according to the order of admission. The control group was treated with traditional Chinese medicine bamboo pot therapy. The experimental group was treated with traditional Chinese medicine bamboo pot combined with somatosensory music therapy. After 4 weeks, the curative effect, VAS score and satisfaction of the two groups were evaluated. Results After treatment, the curative effect of the experimental group was better than that of the control group (P<0.01); the VAS score of the experimental group and the control group was lower than that before treatment, but the VAS score of the experimental group was lower (P<0.01); the satisfaction of the experimental group and the control group was higher than that before treatment, while the satisfaction of the experimental group was more satisfactory (P<0.01). Conclusion The traditional Chinese medicine bamboo pot combined with somatosensory music therapy may alleviate muscle spasm, relax body and mind, promote blood circulation and remove blood stasis, warm tendons and dispel cold.
目的 研究慢性非特异性腰痛患者腰椎正侧位X线中腰椎侧弯、L1-5棘突偏歪和椎体滑脱情况,总结规律,为慢性非特异性腰痛患者治疗提供依据。方法 选取164例慢性非特异性腰痛患者,观察并记录每例患者腰椎正侧位X线中腰椎侧弯、L1~L5棘突偏歪和椎体滑脱情况。用统计学软件分析腰椎侧弯、棘突偏歪和椎体滑脱情况。结果 共有59例发生腰椎侧弯,占35.98%,其中Cobb角5°~10 °有47例,占28.66%;Cobb角>10°有12例,占7.32%。腰椎侧弯发病以L4为下端椎为主。以L3为下端椎有12例患者,占20.34%;以L4为下端椎有37例患者,占62.71%;以L5为发椎有10例患者,占16.95%。共119例发生棘突偏歪,占总例数的72.56%。L5棘突偏歪最常见,发生率为57.93%;L4次之,发生率为48.17%。L5棘突偏歪率与L1~L3棘突偏歪率比较差异均有统计学意义(χ 2 分别为14.580,11.771,7.484,P分别为<0.001,0.001,0.006),但与L4棘突偏歪率比较差异无统计学意义(χ 2 =3.124,P=0.077)。共30例患者存在椎体滑脱,占18.29%。L5最常发生滑脱,发生率为8.54%;L4次之,发生率为7.93%。L4与L5椎体滑脱率比较差异无统计学意义(χ 2 =0.040,P=0.841);L4分别与L1,L2,L3以及L5分别与L1,L2,L3椎体滑脱率差异均有统计学意义(L5与L1、L2、L3:χ 2 分别为14.580、11.771、7.484,P分别为<0.001、0.001、0.006;L4与L1、L2、L3:χ 2 分别为13.495、10.712、6.550,P分别为<0.001、0.001、0.010)。结论 慢性非特异性腰痛患者较常发生腰椎侧弯,侧弯以L4为下端椎为主;慢性非特异性腰痛患者较常发生棘突偏歪,L5棘突偏歪最常见,L4次之;L5和L4是慢性非特异性腰痛患者最常发生滑脱的椎体。在治疗慢性非特异性腰痛患者时,与L5和L4相关的肌肉、筋膜等软组织损伤以及关节退行性变或紊乱应引起重点关注。
Objective To study the lumbar scoliosis,L1-5 spinous process deviation and spondylolisthesis in spine X-ray of patients with chronic non-specific low back pain(CNLBP),and summarizing the existing rules,so as to provide imaging theoretical support for the treatment of CNLBP.Methods A total of 164 patients with CNLBP were selected.The lumbar scoliosis,L1-5 spinous process deviation and spondylolisthesis were observed and recorded in the anteroposterior and lateral X-ray films of each patient.The lumbar scoliosis,spinous process deviation and spondylolisthesis were statistically analyzed by statistical software.Results A total of 59 people had lumbar scoliosis,accounting for 35.98%.There were 47 patients with 5°-10° Cobb angle,accounting for 28.66%.There were 12 patients with Cobb angle >10°,accounting for 7.32%.L4 was the main lower apical vertebra of lumbar scoliosis.There were 12 patients with L3 as the lower apical vertebra,accounting for 20.34%;37 patients with L4 as the lower apical vertebra,accounting for 62.71%;10 patients with L5 as the lower apical vertebra,accounting for 16.95%.A total of 119 people appeared spinous process deviation,accounting for 72.56%.L5 spinous process deviation was the most common,with proportion of 57.93%,and L4 was the second,with proportion of was 48.17%.The results of chi-square test showed that there were significant differences between L5 and L1-L3 spinous process deviation(χ 2 was 14.580,11.771,7.484,and P values were <0.001,0.001,0.006 respectively),but no significant difference between L5 and L4 spinous process(χ 2 =3.124,P=0.077).A total of 30 patients had spondylolisthesis,accounting for 18.29%.L5 was the most common of spondylolisthesis,with an occurrence rate of 8.54%.L4 was the second,with an occurrence rate of 7.93%.There was no significant difference in spondylolisthesis rate between L4 and L5(χ 2 =0.040,P=0.841).The spondylolisthesis rates of L4 and L5 were significantly different from those of L1,L2 and L3(L5 and L1,L2,L3:χ 2 was 14.580,11.771,7.484,and P values was <0.001,0.001,0.006 respectively;L4 and L1,L2,L3:χ 2 was 13.495,10.712,6.550,P values were <0.001,0.001,0.010 respectively).Conclusions Lumbar scoliosis is more common in patients with CNLBP,and L4 is the main lower apical vertebra of lumbar scoliosis.Patients with CNLBP often have spinous process deviation,and the most common is L5 spinous process deviation,followed by L4.L5 and L4 are the most common vertebrae with spondylolisthesis in patients with CNLBP.The soft injury and joint degeneration or disorder related to L5 and L4 should be paid more attention in the treatment of patients with CNLBP.
目的 应用 Python语言对《圣济总录》中腰痛病篇中的中药进行用药规律分析,提取腰痛病治疗方法及用药特色指导临床腰痛病治疗思路。方法 运用 Python语言中的语言提取对《圣济总录》中腰痛篇章中的所有中药方剂识别,提取方剂组成,统计并分析方剂中中药的规律并将其结果可视化呈现。结果 最终共纳入62首方剂,包含药物86味。其中使用频次≥7次、频率≥1.6%的药物共20味,频次频率最高的为桂枝;所用中药四气以温性为主,占56.74%;五味以辛、甘、苦为主,共约占90%,归经以肝肾经为主;药物功效以补虚类为主,占27.13%;关联规则分析显示提升度最高的组合为麻黄-独活,置信度最高的组合为巴戟天-牛膝、牵牛子-牛膝,支持度最高的组合为川芎-当归、川芎-杜仲;通过聚类分析得到3个聚类结果。结论 《圣济总录》治疗腰痛病方面善用通法和补法,强调活血通络,补益肝肾,尤擅长治疗肝肾亏虚或风寒所客等腰痛病证。
Objective Python language was used to analyze the rules of traditional Chinese medicine in the chapter of low back pain in Shengji Zonglu,and to extract the treatment methods and medication characteristics of low back pain to guide the clinical treatment of low back pain.Methods The language extraction in Python language was used to identify all the Chinese medicine prescriptions in the chapter of low back pain in Shengji Zonglu,extract the composition of the prescription,and analyze the rules of Chinese medicine in the prescription to visually present the results.Results A total of 62 prescriptions were included,including 86 drugs.Among them,with there were 20 kinds of drugs,the frequency of use ≥7 times,the frequency ≥1.6%,and cmnamomi Mmulus highest frequency.Four gas used in traditional Chinese medicine is given priority to with warm,accounted for 56.74%.The five flavors were mainly pungent,sweet and bitter,accounting for about 90%,and the liver and kidney meridians were the main meridians.The drug efficacy was mainly deficiency tonic,accounting for 27.13%.The association rule analysis showed that the combination with the highest improvement was Ephedrae Herba- Angelicae Pubescentis Radix,the combination with the highest confidence was Morindae Officinalis Radix- Achyranthis Bidentatae Radix,Pharbitidis Semen- Achyranthis Bidentatae Radix.and the combination with the highest support was Chuanxiong Rhizoma- Angelicae Sinensis Radix,Chuanxiong Rhizoma- Eucommiae Cortex.Three clustering result is obtained by cluster analysis.Conclusions In the treatment of low back pain,Shengji Zonglu is good at using both blocking methods and reinforcing methods,emphasizing circulating blood and unblocking meridians supplementing liver and kidney,especially in the treatment of low back pain syndrome caused by liver and kidney deficiency or wind and cold.