Objective To review the clinical characteristics of early postoperative inflammatory small bowel obstruction(EPISBO) in children with appendicitis in plateau area and summarize the treatment experience.Methods The data of 49 cases of appendicitis EPISBO in children admitted to Qinghai Women and Children’s Hospital from 2019 to 2023 were retrospectively analyzed.Results The onset time of appendicitis was 3-8 days,with an average of(5.38±1.25)days,and the time of intestinal obstruction was 3-11 days after surgery,with an average of(4.81±1.70)days.After conservative treatment,48 cases were relieved of obstruction,resumed exhaust and defecation,and intestinal function recovered in 4-13 day,average(5.93±2.49)d,1 case had progression after conservative treatment,and was cured by surgery.All the 49 children were successfully cured and discharged.The length of hospital stay was 10-26 days,with an average of(15.69±3.79)days.Postoperative follow-up of 1 to 2 years showed normal eating and bowel movements.Conclusions The prevention of EPISBO in children with appendicitis in plateau area is the key.Conservative treatment can also achieve a higher cure rate.If conservative treatment is ineffective or the disease progresses,timely surgical treatment should be provided.