冠状动脉血管成像联合动态心电图与冠心病冠脉狭窄程度及预后的关联研究

Study on the correlation between Coronary CT angiography combined with dynamic electrocardiogram and the degree and prognosis of coronary stenosis in coronary heart disease

:-
 
目的:分析冠状动脉CT血管成像(CTA)联合动态心电图(DCG)与冠心病患者冠脉狭窄程度及预后情况的关联。方法:研究对象选择我院2024年1月~2025年3月收治的210例冠心病患者及同期接受检查的210例非冠心病患者,分别列为病例组和对照组,比较两组CTA参数、DCG参数间差异。依据入院测得(Gensini)评分不同,将入组患者分别列为轻度组(60例,Gensini评分≤30分)、中度组(75例,Gensini评分>30分、≤60分)和重度组(75例,Gensini评分>60分),比较三组CTA参数、DCG参数间差异,分析CTA参数、DCG参数与Gensini评分的相关性。统计入组患者不良预后发生情况,比较不同预后患者CTA参数、DCG参数间差异,归纳冠心病患者预后影响因素,检验CTA参数、DCG参数对患者不良预后的预测效能。结果:病例组的最小管腔直径(MLD)、最小管腔面积(MLA)、血流储备分数(FFR)、正常窦性间期的标准差(SDNN)、每5min平均RR间期的标准差(SDANN)、相邻RR间期差值的均方根(RMSSD)均低于对照组,斑块总体积(TPV)、低频/高频比值(LF/HF)均高于对照组(t=24.128,25.811,15.613,37.636,26.858,9.195,59.862,29.389;P<0.05)。重度组的MLD、MLA、FFR、SDNN、SDANN、RMSSD均低于中度组,轻度组,TPV、LF-HF均高于中度组,轻度组(F=190.291,51.562,186.482,42.084,44.413,22.541,56.503,109.983;P<0.05)。MLD、MLA、FFR、SDNN、SDANN、RMSSD均与Gensini评分负相关,TPV、LF-HF均与Gensini评分正相关(r=-0.352,-0.377,-0.445,-0.472,-0.332,-0.356,0.401,0.355;P<0.05)。经统计,210例冠心病患者的不良预后发生率为38.10%(80/210)。预后不良组的MLD、MLA、FFR、SDNN、SDANN、RMSSD均低于预后良好组,TPV、LF-HF均高于预后良好组(t=6.827,12.219,19.313,6.097,7.097,5.027,7.088,12.465;P<0.05)。MLA、FFR、SDNN升高为冠心病不良预后的保护因素,LF/HF升高为冠心病不良预后的危险因素。FFR、SDNN联合检测预测不良预后的 AUC 值优于两项指标单独检测(Delong检验,P<0.05)。结论:CTA、DCG能客观评估冠心病患者冠脉狭窄程度,联合检测FFR、SDNN可作为预测冠心病不良预后的重要辅助手段。
Objective:To analyze the correlation between CTA combined with DCG and the degree of coronary stenosis and prognosis in patients with coronary heart disease.Methods:The research subjects selected were 210 patients with coronary heart disease admitted to our hospital from January 2024 to March 2025, as well as 210 non coronary heart disease patients who underwent examinations during the same period. They were divided into a case group and a control group. The differences in CTA parameters and DCG parameters between the two groups were compared. According to the different Gensini scores obtained upon admission, the enrolled patients were divided into mild group (60 cases, Gensini score ≤ 30 points), moderate group (75 cases, Gensini score>30 points, ≤ 60 points), and severe group (75 cases, Gensini score>60 points). The differences in CTA parameters and DCG parameters among the three groups were compared, and the correlation between CTA parameters, DCG parameters, and Gensini score was analyzed. Statistically analyze the occurrence of poor prognosis in enrolled patients, compare the differences in CTA and DCG parameters among patients with different prognoses, summarize the factors affecting the prognosis of coronary heart disease patients, and test the predictive power of CTA and DCG parameters for poor prognosis in patients.Results:The MLD, MLA, FFR, SDNN, SDANN, and RMSSD in the case group were all lower than the control group, while the TPV and LF/HF were higher than the control group (t=24.128,25.811,15.613,37.636,26.858,9.195,59.862,29.389; P<0.05). The MLD, MLA, FFR, SDNN, SDANN, and RMSSD of the severe group were lower than the moderate group, mild group, while the TPV and LF-HF of the mild group were higher than the moderate group, mild group (F=190.291,51.562,186.482,42.084,44.413,22.541,56.503,109.983; P<0.05). MLD, MLA, FFR, SDNN, SDANN, and RMSSD are all negatively correlated with Gensini score, while TPV and LF-HF are positively correlated with Gensini score (r=-0.352,-0.377,-0.445,-0.472,-0.332,-0.356,0.401,0.355; P<0.05). According to statistics, the incidence of poor prognosis in 210 patients with coronary heart disease was 38.10% (80/210). The MLD, MLA, FFR, SDNN, SDANN, and RMSSD of the poor prognosis group were lower than the good prognosis group, while TPV and LF-HF were higher than the good prognosis group (t=6.827,12.219,19.313,6.097,7.097,5.027,7.088,12.465; P<0.05). High MLA, FFR, and SDNN are protective factors for poor prognosis of coronary heart disease, while higher values than LF/HF are risk factors for poor prognosis of coronary heart disease. The combined detection of FFR and SDNN has a better AUC value for predicting poor prognosis of coronary heart disease than the detection of FFR and SDNN alone (Delong test, P<0.05).Conclusion:CTA and DCG can objectively evaluate the degree of coronary stenosis in patients with coronary heart disease, and combined detection of FFR and SDNN can be an important auxiliary tool for predicting poor prognosis of coronary heart disease.
论著

眼科患者荧光素眼底血管造影认知及健康教育需求分析

Investigation on fundus fluorescein angiography cognition and health education needs in ophthalmic patients

:44-50
 
目的 调查眼科患者对荧光素眼底血管造影认知情况及健康教育需求,为眼底造影医护人员实施高效、个性化健康教育提供依据。方法 采用自制眼底造影认知及健康教育需求问卷,对本院2021年6月—8月的123例眼底血管造影患者进行问卷调查,使用Spearman相关性分析、非参数秩和检验及多元线性逐步回归分析患者眼底血管造影认知的影响因素。结果 患者荧光素眼底血管造影认知得分为(33.77±8.09)分,其中,患者对于检查中的相关知识认知最低,相对得分为0.59;患者健康教育需求的得分为(43.95±7.63)分,其中,检查后的相关知识需求度最高,相对得分为0.77;不同年龄、文化程度、主要照顾者、眼造影检查次数及是否合并全身病的患者的认知水平差异有统计学意义(P<0.05)。多元线性逐步回归分析表明,眼造影检查史是患者眼底血管造影认知的独立影响因素。结论 眼科患者对荧光素眼底血管造影认知水平较低,健康教育需求高,医护人员应重视健康教育的实施,结合FFA操作流程及患者特点,制定标准化健康教育流程,探索有效的线上+线下的健康教育模式,以提高造影患者认知水平,保障患者安全。
Objective To investigate fundus fluorescein angiography(FFA)cognition and health education needs in ophthalmic patients,and to provide basis for efficient and personalized health education for FFA medical staff.Methods A self-made questionnaire was used in a survey of 123 patients from June to August 2021.The influencing factors of FFA cognition were analyzed by Spearman correlation analysis,non parametric rank sum test and multiple linear stepwise regression.Results The score of FFA cognition was(33.77 ± 8.09).Patients had the lowest cognition of relevant knowledge during the examination,with a relative score of 0.59.The score of patient's health education needs was(43.95 ± 7.63),while the score of relevant knowledge needs after examination was the highest,with a relative score of 0.77.There were significant differences in cognitive level among patients with different ages,educational levels,main caregivers,angiographic times,and complication of systemic diseases(P<0.05).Multiple linear stepwise regression analysis showed that the number of ocular angiography was an independent factor affecting the cognition of FFA.Conclusions Patients with FFA have low cognitive level and high demand for health education.Medical staff should pay attention to the implementation of health education,formulate a standardized health education process with the combination of operation process and patient characteristics,and explore an effective online-to-offline health education mode,so as to improve the cognitive level of angiography patients and ensure the safety of patients.
论著

平板运动试验阳性者冠脉造影结果预警冠心病

Results of coronary angiography in patients with positive treadmill exercise test give early warning of coronary heart disease

:28-31
 
目的 分析平板运动试验阳性患者行冠脉造影检查后结果阳性者与冠心病的高危因素的关联性,从而预警冠心病。方法 选取浙江大学医学院附属第二医院2016年3月—2019年3月行平板运动试验的阳性患者经冠脉造影结果为阳性,且资料完整者280例患者为研究对象,筛选出影响冠心病的独立危险因素。结果 性别、体质量指数(BMI)、高甘油三酯、平板恢复1、2 min心率是影响冠心病的独立危险因素。结论 对于男性、BMI>24、高甘油三酯、平板恢复1、2 min心率异常的患者,当其平板运动试验为阳性时,应建议其进一步行冠脉造影检查。
Objective To analyze the correlation between coronary angiography and the risk factors of coronary heart disease in patients with positive treadmill exercise test, so as to give early warning of coronary heart disease. Methods A total of 280 patients who underwent treadmill exercise tests from March 2016 to March 2019 in the Second Affiliated Hospital of Medical College of Zhejiang University were selected as the study subjects with positive coronary angiography results and complete data to screen out independent risk factors for coronary heart disease. Results Gender, body mass index, high triglycerides, high cholesterol, heart rate after 1 or 2 minutes of tablet recovery were the risk factors for positive coronary angiography. Conclusion For men, patients with BMI>24, high triglycerides, and abnormal heart rate after 1 or 2 minutes of tablet recovery, when the treadmill exercise test is positive, further coronary angiography should be recommended.
论著

风险防范护理干预对控制冠状动脉造影术后患者血管并发症的影响

Effect of risk prevention nursing intervention on controlling vascular complications in patients after coronary angiography

:356-360
 
      目的   探讨在冠状动脉造影术后患者中应用风险防范护理干预对血管并发症的控制效果。方法   选择2022年1月—2023年6月于我院接受治疗的85例冠状动脉造影术后患者。按照随机数字表法分组,其中对照组42例给予常规护理干预,观察组43例给予风险防范护理干预,比较两组干预前后的心理状态、治疗依从性、血管并发症。结果   干预后,观察组正性情绪(PA)评分高于对照组PA评分(t=3.821,P<0.001),观察组负性情绪(NA)评分低于对照组NA评分(t=5.380,P<0.001)。与对照组比,观察组治疗依从性更好(Z=2.268,P=0.023)。观察组血管并发症总发生率低于对照组(9.30% vs 30.95%,χ 2 =6.224,P=0.013)。结论   采用风险防范护理干预,能够改善冠状动脉造影术后患者的心理状态,提高治疗依从性,并降低血管并发症总发生率。
       Objective  To explore the effect of  risk prevention nursing intervention on controlling vascular complications in patients after coronary angiography.Methods  Eighty-five patients after coronary angiography in our hospital were selected from January 2022 to June 2023.They were grouped according to the random number table.And 42 cases were divided into the control group for routine nursing intervention,and 43 cases in the observation group were given risk prevention nursing intervention.Psychological status,treatment compliance and vascular complications of the two groups were observed.Results  After the intervention,the postive affect score of the observation group was higher than that of the control group(t=3.821,P<0.001),and the negative affect score of the observation group(21.25±3.31)was lower than the score of the control group(25.35±3.70)t=5.380,P<0.001).Compared with the control group the compliance of observation group was higher(Z=2.268,P=0.023).The overall incidence of vascular complications in the observation group was lower than that in the control group(9.30% vs 30.95%,χ2=6.224,P=0.013).Conclusions  Risk prevention nursing intervention can improve the psychological status of patients after coronary angiography,improve treatment compliance,and reduce the overall incidence of vascular complications.
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