Objective To investigate the clinical application value of novel light-cured TheraCal LC pulp capping agent in children receiving deciduous teeth pulpotomy. Methods A retrospective study was performed on clinical data of 90 children who underwent deciduous teeth pulpotomy from August 2023 to May 2025. Subjects were divided according to different capping materials: 45 cases using TheraCal LC as study group, another 45 cases treated with iRoot BP Plus as control group. The treatment success rate, pain score, masticatory efficiency, gingival crevicular fluid inflammatory factors [interleukin-6 (IL-6), matrix metalloproteinase-3 (MMP-3)], root resorption, dentin bridge formation and adverse reactions were compared between two groups. Results There was no significant difference was found in treatment success rate at 12 months after operation between groups (P>0.05). At postoperative 3 months, the study group had lower pain score and higher masticatory efficiency than the control group (P<0.05), whereas no intergroup differences were observed at 6 and 12 months (P>0.05). The levels of gingival crevicular fluid IL-6 and MMP-3 in study group were significantly lower at 3, 6 and 12 months postoperatively (P<0.05). There was no significant difference in root resorption degree and dentin bridge formation rate at postoperative 12 months (P>0.05). No pulp inflammation, tooth discoloration or secondary caries occurred in either group. Conclusion The novel light-cured TheraCal LC shows favorable overall efficacy and safety in deciduous teeth pulpotomy; it can effectively suppress early gingival inflammation, relieve early postoperative pain and improve early masticatory function.
目的 探讨3M复合树脂填充乳牙龋齿患儿治疗中的临床价值。方法 回顾性收集2023年4月至2025年4月我院口腔科128例乳牙龋齿患儿临床资料,根据治疗方法不同分为对照组(高强度玻璃离子填充,67例)、观察组(3M复合树脂填充,61例),采用倾向匹配评分法匹配,按照1:1配对选例,两组均纳入53例。比较两组疗效、治疗前后疼痛程度[Wong-Baker面部疼痛评分量表(Wong-Baker评分)]、牙髓活力、牙齿敏感性、龈沟液炎症因子[白细胞介素(IL)-6、IL-8、单核细胞趋化蛋白-1(MCP-1)]、儿童口腔健康影响量表(ECOHIS)评分及并发症。结果 观察组治疗总有效率94.34%高于对照组81.13%(P<0.05);治疗后1周观察组Wong-Baker评分、牙髓活力评分低于对照组,牙齿敏感性分级优于对照组(P<0.05);治疗后1周,观察组龈沟液IL-6、IL-8、MCP-1水平低于对照组(P<0.05);治疗后6个月,观察组口腔症状、口腔功能、心理状态评分低于对照组(P<0.05);两组并发症发生率比较,无显著差异(P>0.05)。结论 3M复合树脂填充治疗乳牙龋齿患儿效果显著,能抑制龈沟液炎症,降低牙齿敏感性,提升牙髓活力,缓解患儿疼痛,改善口腔健康,且安全性较高。
目的 探讨单次根管疏通填充对牙体牙髓病患者的填充效果及龈沟液炎症指标的影响。方法 选择2023年8月—2024年2月天津市人民医院接收的牙体牙髓病患者84例进行研究,采用随机数字表法分为两组,各42例。对照组采取多次根管疏通填充,观察组采取单次根管疏通填充,比较2组填充效果、治疗效果、龈沟液炎症指标、口腔健康和功能指标、并发症情况。结果 观察组欠填、恰填、超填比例与对照组比较无统计学意义(χ2分别为0.262、1.615、0.512,P分别为0.608、0.203、0.474)。观察组的总有效率为97.62%,高于对照组80.95%(χ2=6.098,P=0.014)。治疗后,观察组龈沟液白细胞介素IL-1β、IL-17A、IL-35、肿瘤坏死因子-α水平低于对照组(t分别为3.271、3.028、2.699、2.968,P分别为0.002、0.003、0.008、0.004)。治疗后,观察组龈沟出血指数、牙龈指数低于对照组,咬合力、咀嚼效率高于对照组(t分别为2.311、2.686、2.262、2.776,P分别为0.023、0.009、0.026、0.007)。观察组并发症发生率4.76%低于对照组21.43%(χ2=5.126,P=0.024)。结论 牙体牙髓病采取单次根管疏通填充治疗可保证恰当的填充效果,取得良好的治疗效果,而且减轻龈沟液炎症反应,促进口腔健康和功能改善,并发症较少,安全性高,值得推广。
Objective To explore the effects of one-time root canal dredging and filling on the filling effect and gingival crevicular fluid inflammation indexes in patients with endodontic disease.Methods A total of 84 cases of endodontic patients admitted to the Tianjin People's Hospital from August 2023 to February 2024 were chosen and separated into the control group(n=42,multiple-time root canal dredging and filling)and the observation group(n=42,one-time root canal dredging and filling)by random number table method.The filling effect,therapeutic effect,gingival creval fluid inflammation indicators,oral health and function indicators,and complications were compared.Results The underfilling,accurate filling and overfilling showed no significant difference between the two groups(χ2=0.262,1.615,0.512,P=0.608,0.203,0.474).The total effective rate of observation group was 97.62%,higher than that of control group 80.95%(χ2=6.098,P=0.014).After treatment,levels of interleukin(IL)-1β,IL-17A,IL-35 and tumor necrosis factor-α in gingival crevicular fluid of observation group were lower(t=3.271、3.028、2.699、2.968,P=0.002、0.003、0.008、0.004).After treatment,the sulcus bleeding index and gingival index of the observation group were lower,and the biting force and mastication efficiency were higher(t=2.311、2.686、2.262、2.776,P=0.023、0.009、0.026、0.007).The complication rate in the observation group was 4.76%,lower than that in the control group 21.43%(χ2=5.126,P=0.024).Conclusions A one-time root canal dredging and filling treatment for endodontic diseases can ensure proper filling effect,achieve good therapeutic effect,reduce gingival crevicular fluid inflammation,promote oral health and function improvement,with fewer complications,high safety,which is worthy of promotion.
目的 探讨单次根管疏通填充对牙体牙髓病患者的填充效果及龈沟液炎症指标的影响。方法 选择2023年8月—2024年2月天津市人民医院接收的牙体牙髓病患者84例进行研究,采用随机数字表法分为两组,各42例。对照组采取多次根管疏通填充,观察组采取单次根管疏通填充,比较2组填充效果、治疗效果、龈沟液炎症指标、口腔健康和功能指标、并发症情况。结果 观察组欠填、恰填、超填比例与对照组比较无统计学意义(χ 2 分别为0.262、1.615、0.512,P分别为0.608、0.203、0.474)。观察组的总有效率为97.62%,高于对照组80.95%(χ 2 =6.098,P=0.014)。治疗后,观察组龈沟液白细胞介素IL-1β、IL-17A、IL-35、肿瘤坏死因子-α水平低于对照组(t分别为3.271、3.028、2.699、2.968,P分别为0.002、0.003、0.008、0.004)。治疗后,观察组龈沟出血指数、牙龈指数低于对照组,咬合力、咀嚼效率高于对照组(t分别为2.311、2.686、2.262、2.776,P分别为0.023、0.009、0.026、0.007)。观察组并发症发生率4.76%低于对照组21.43%(χ 2 =5.126,P=0.024)。结论 牙体牙髓病采取单次根管疏通填充治疗可保证恰当的填充效果,取得良好的治疗效果,而且减轻龈沟液炎症反应,促进口腔健康和功能改善,并发症较少,安全性高,值得推广。
Objective To explore the effects of one-time root canal dredging and filling on the filling effect and gingival crevicular fluid inflammation indexes in patients with endodontic disease.Methods A total of 84 cases of endodontic patients admitted to the Tianjin People’s Hospital from August 2023 to February 2024 were chosen and separated into the control group(n=42,multiple-time root canal dredging and filling)and the observation group(n=42,one-time root canal dredging and filling)by random number table method.The filling effect,therapeutic effect,gingival creval fluid inflammation indicators,oral health and function indicators,and complications were compared.Results The underfilling,accurate filling and overfilling showed no significant difference between the two groups(χ 2 =0.262,1.615,0.512,P=0.608,0.203,0.474).The total effective rate of observation group was 97.62%,higher than that of control group 80.95%(χ 2 =6.098,P=0.014).After treatment,levels of interleukin(IL)-1β,IL-17A,IL-35 and tumor necrosis factor-α in gingival crevicular fluid of observation group were lower(t=3.271、3.028、2.699、2.968,P=0.002、0.003、0.008、0.004).After treatment,the sulcus bleeding index and gingival index of the observation group were lower,and the biting force and mastication efficiency were higher(t=2.311、2.686、2.262、2.776,P=0.023、0.009、0.026、0.007).The complication rate in the observation group was 4.76%,lower than that in the control group 21.43%(χ 2 =5.126,P=0.024).Conclusions A one-time root canal dredging and filling treatment for endodontic diseases can ensure proper filling effect,achieve good therapeutic effect,reduce gingival crevicular fluid inflammation,promote oral health and function improvement,with fewer complications,high safety,which is worthy of promotion.