胃癌患者围手术期口服营养补充管理的临床效果及对营养状态与康复进程的影响研究

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目的 探讨基于围手术期的口服营养补充(ONS)管理方案对胃癌手术患者的影响。方法 选取2020.1-2025.12本院收治的80例胃癌手术患者,分为观察组和对照组,每组40例。对照组实施围手术期常规膳食指导及肠外营养支持,观察组在对照组基础上实施规范化口服营养补充管理,比较相关指标。结果 术后7d,观察组总蛋白、白蛋白、前白蛋白水平均高于对照组(P<0.001);观察组术后CRP及IL-6水平低于对照组(P<0.001)。观察组术后首次排气时间及住院天数短于对照组(P<0.001);观察组术后并发症总发生率为7.50%,显著低于对照组的25.00%(P<0.05)。结论 胃癌围手术期实施口服营养补充管理,对营养状况的改善,炎症反应的减轻,胃肠功能的恢复,住院时间的缩短,降低并发症风险。

胃癌患者围手术期口服营养补充管理的临床效果及对营养状态与康复进程的影响研究

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目的 探讨基于围手术期的口服营养补充(ONS)管理方案对胃癌手术患者的影响。方法 选取2020.1-2025.12本院收治的80例胃癌手术患者,分为观察组和对照组,每组40例。对照组实施围手术期常规膳食指导及肠外营养支持,观察组在对照组基础上实施规范化口服营养补充管理,比较相关指标。结果 术后7d,观察组总蛋白、白蛋白、前白蛋白水平均高于对照组(P<0.001);观察组术后CRP及IL-6水平低于对照组(P<0.001)。观察组术后首次排气时间及住院天数短于对照组(P<0.001);观察组术后并发症总发生率为7.50%,显著低于对照组的25.00%(P<0.05)。结论 胃癌围手术期实施口服营养补充管理,对营养状况的改善,炎症反应的减轻,胃肠功能的恢复,住院时间的缩短,降低并发症风险。

胃癌患者围手术期口服营养补充管理的临床效果及对营养状态与康复进程的影响研究

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目的 探讨基于围手术期的口服营养补充(ONS)管理方案对胃癌手术患者的影响。方法 选取2020.1-2025.12本院收治的80例胃癌手术患者,分为观察组和对照组,每组40例。对照组实施围手术期常规膳食指导及肠外营养支持,观察组在对照组基础上实施规范化口服营养补充管理,比较相关指标。结果 术后7d,观察组总蛋白、白蛋白、前白蛋白水平均高于对照组(P<0.001);观察组术后CRP及IL-6水平低于对照组(P<0.001)。观察组术后首次排气时间及住院天数短于对照组(P<0.001);观察组术后并发症总发生率为7.50%,显著低于对照组的25.00%(P<0.05)。结论 胃癌围手术期实施口服营养补充管理,对营养状况的改善,炎症反应的减轻,胃肠功能的恢复,住院时间的缩短,降低并发症风险。
论著

术前控制营养状态评分在老年胃癌患者术后短期并发症中的应用价值

Application value of controlling nutritional status score in short-term postoperative complications of elderly patients with gastric cancer

:28-35
 
目的 探讨术前控制营养状态评分在老年胃癌患者术后短期并发症中的应用价值。方法 回顾分析统计2015年1月—2020年12月在江苏大学附属医院接受治疗的确诊胃癌患者,根据纳入标准和排除标准,选择入组患者,收集纳入研究患者一般资料、术前实验室检测数据和术后并发症情况,计算控制营养状况(CONUT)评分,统计分析CONUT营养评分在老年胃癌患者接受胃癌D2根治术术后短期并发症的价值。结果 共223例患者纳入研究,CONUT评分的截断值为2.5,肿瘤直径的截断值为2.75 cm。CONUT评分>2.5组的平均年龄高于CONUT评分<2.5组(P=0.005 3),且2组性别构成存在差异,男性患者多于女性(P=0.037 0)。CONUT评分>2.5组患者的肿瘤直径较大(P=0.039 4)。在术后并发症方面,CONUT评分>2.5组的术后并发症多于CONUT评分<2.5组(P=0.008 3)。单因素Logistic回归分析,年龄(OR=1.127;95%CI:1.028~1.236;P=0.011)、CONUT评分(OR=0.339;95%CI:0.151~0.764;P=0.009)是患者发生短期并发症的危险因素。多因素Logistic回归分析显示年龄(OR=1.115;95%CI:1.008~1.233;P=0.035)、CONUT评分(OR=0.414;95%CI:0.175~0.982;P=0.045)是患者发生短期并发症的危险因素。结论 CONUT评分作为老年胃癌患者术前营养评估项目可以有效预测患者术后短期并发症,进而提前进行营养干预,降低术后并发症发生率。
Objective To explore the value of controlling nutritional status score in short-term postoperative complications of elderly patients with gastric cancer.Methods The data of patients who confirmed gastric cancer and treated in the Affiliated Hospital of Jiangsu University from January 2015 to December 2020 were reviewed and analyzed.Patients were selected according to the inclusion criteria and exclusion criteria,the general data,preoperative laboratory test data and postoperative complications of the included patients were collected,and the controlling nutritional status(CONUT)score was calculated.The value of CONUT score in the short-term complications of elderly gastric cancer patients undergoing D2 radical gastrectomy for gastric cancer was evaluated.Results A total of 223 patients were included in this study.The cut-off value of CONUT score was 2.5 and the cut-off value of tumor diameter was 2.75 centimeter.The average age of the group with CONUT score > 2.5 was significantly higher than that of the group with CONUT score < 2.5(P=0.005 3).Moreover,there was significant difference between the sex ratio of the two groups,with male more than female(P=0.037 0).The tumor diameter was significantly larger in the group with CONUT score > 2.5(P=0.039 4).In terms of postoperative complications,there was significantly more postoperative complications in the group with CONUT score > 2.5 than in the group with CONUT score < 2.5(P=0.008 3).Univariate logistic regression analysis showed that age(OR=1.127;95% CI:1.028-1.236;P=0.011)and CONUT score(OR=0.339;95% CI:0.151-0.764;P=0.009)were the risk factors for short-term complications.Multivariate logistic regression analysis showed that age(OR=1.115;95% CI:1.008-1.233;P=0.035)and CONUT score(OR=0.414;95% CI:0.175-0.982;P=0.045)were the risk factors for short-term complications.Conclusions As a preoperative nutritional evaluation item for elderly patients with gastric cancer,CONUT score can effectively predict the short-term postoperative complications of patients,and then carry out nutritional intervention in advance to reduce the incidence of postoperative complications.
论著

广州地区老年住院患者营养状态与日常生活能力相关性研究

Relationship between nutritional status and activities of daily living in elderly inpatients in Guangzhou

:68-72
 
目的 探讨广州地区老年住院患者营养状态与日常生活能力(ADL)的相关性。方法 选取2018年7月—2019年6月在广州市第一人民医院住院年龄≥60岁的老年人共275例,收集其一般资料信息,各项临床营养指标(BMI、血清白蛋白、血红蛋白、总胆固醇、甘油三酯)、并运用营养风险筛查2002(NRS2002)评估营养风险、采用Barthel指数评定量表评估日常生活能力;分析老年住院患者营养状态与ADL之间的相关性。结果 在本组研究中,根据NRS2002评分(营养风险:NRS2002≥3;无营养风险NRS2002<3),营养风险发生率58.9%(162/275);无营养风险发生率41.1%(113/275)。老年住院患者的NRS2002评分与ADL评分呈负相关关系(r=-0.393,P<0.05);ADL评分与BMI、血清白蛋白、总胆固醇、血红蛋白水平呈正相关关系(P<0.05)。结论 广州地区老年住院患者NRS2002为日常生活能力的影响因素,通过降低NRS2002评分来减少营养风险可改善老年人的日常生活能力;老年人的营养风险发生率高,应当尽早进行营养干预。
Objective To investigate relationship between nutritional status and activities of daily living(ADL) in elderly inpatients in Guangzhou. Methods Total of 275 people older than 60 were included in this study from Guangzhou First People's Hospital from July 2018 to June 2019. Their nutritional markers(including BMI, plasma albumin, hemoglobin, total cholesterol, triglyceride),the activities of daily living(ADL) were evaluated with Barthel index and the nutrition risk screening 2002(NRS2002)used to assess the nutritional risk status were collected to analyze the relationship between nutrition and ADL. Results In these subjects, based on the NRS2002 scores(nutritional risk that the NRS2002 scores were equal or greater than 3, and the non-nutritional risk that the NRS2002 scores were less than 3),58.9%(162/275) patients were having nutritional risk and 41.1%(113/275) were having non-nutritional risk. In elderly inpatients,NSR2002 were negatively associated with ADL(r=-0.393,P<0.05). ADL was positively associated with BMI, plasma albumin and hemoglobin level(P<0.05). Conclusion In the old, the NRS2002 is an influencing marker of activities of daily living in Guangzhou. Reducing the nutritional risk by lowering the NRS2002 scores can improve ADL in the elderly. The incidence of nutritional risk is highly prevalent in elderly and early nutritional treatment will be needed.
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