目的 探讨心理干预联合补佳乐在绝经后妇女宫内节育器(IUD)取出术中的临床效果。方法 选取2012年10月—2015年9月在本站施行IUD取出术的绝经后妇女200例,随机分为观察组和对照组各100例,对照组在手术前给予口服补佳乐1 mg 每日1次 连服7天,第8天施行取出术,观察组在对照组的基础上配合心理干预,观察两组在手术过程中的疼痛程度、宫颈松弛度、心理紧张度的差异。结果 IUD取出术中疼痛程度,观察组:0级 53%,1级40.0%, 2级7.0%,3级0%;对照组:0级14.0%,1级27.00%,2级44.0%,3级15.0%。观察组患者IUD取出术中成功率、满意度分别为87%、96%,与对照组比较,两者差异均有统计学意义(P<0.05)。结论 心理干预联合补佳乐应用于绝经后IUD取出术,可有效改善生殖器的施术条件,减少受术者痛苦,安全、有效,效果满意。

目的 探讨绝经期后女性血清铁蛋白水平与代谢综合征之间的关系。方法 收集218例确诊为MS的绝经期后女性患者为试验组,对照组为经我院检查健康绝经期后的女性300例,分别测FBG、TC、TG、LDL-C、HDL-C、HbA1C、INS、SF;计算体重指数(BMI)以及测量腰围;测血压;用HOMA稳态模型来评价胰岛素抵抗指数(HOMA-IR)。结果 MS组较非MS组的铁蛋白(SF)值高(P<0.01),SF四分位各组之间比较,FBG、TG、HDL-C,BMI,腰围,收缩压、舒张压有差异(P<0.05或P<0.01),四组间年龄、TC、LDL-C无差异。与SF呈正相关的参数有腰围(P<0.01),舒张压(P<0.01),空腹血糖(P<0.01),胰岛素抵抗指数(P<0.01),负相关的参数为HDL-C(P<0.01)。结论 绝经期后女性的SF水平与MS呈显著相关,其中腰围、舒张压、空腹血糖、HDL-C、胰岛素抵抗指数与血清铁蛋白之间存在较大关联性。

Objective To study the relationship of serum ferritin level with metabolic syndrome in postmenopausal women. Methods 218 postmenopausal women with metabolic syndrome and 300 healthy postmenopausal women were included in this investigation, to detect FBG, TC, TG, LDL- C, HDL-C, HbA1C, INS, SF, calculated body mass index (BMI) and to measure waist circumference, blood pressure; Using HOMA steady-state model to evaluate indexes of insulin resistance (HOMA IR). Results Serum ferritin level was significantly higher in MS group than in the non-MS group(P<0.01). Serum ferritin quarterback was compared between each group, there were differences in FBG, TG, HDL-C,BMI, waist circumference,SBP, DBP(P<0.05 or P<0.01). There were no differences in age, TC, LDL-C. Serum ferritin level was significantly positive correlated with waist circumference (P<0.01), DBP(P<0.01), FBG(P<0.01), insulin resistance index (P<0.01), and negative correlation with HDL-C(P<0.01). Conclusion Serum ferritin level is significantly associated with metabolic syndrome in postmenopausal women. Waist circumference, DBP, FBG, HDL -C, insulin resistance index are closely associated with the serum ferritin.

目的 探讨妈富隆用于治疗围绝经期功血的临床效果。方法 选择年龄40~53岁的出现围绝经期功血的育龄妇女100例。采用盲选法随机分为观察组和对照组,每组各50例。观察组诊刮后第5天开始口服妈富隆,开始每次服1片,每8 h服1次,血止后每3天递减1/3剂量,至维持量1片/天,共计21天,停药后撤退性出血的第5天开始服下周期的药;对照组诊刮后第15天开始口服醋酸甲羟孕酮片,10 mg/天,连服10 天停药后撤退性出血的第15天开始服下周期的药;两组各连服3个周期。结果 观察组服药后阴道流血控制时间和完全止血时间明显短于对照组,在治疗效果方面,观察组总有效率90%,对照组48%,观察组疗效优于对照组。结论 妈富隆治疗围绝经期功血的效果优于孕激素后半周期治疗围绝经期功血的效果,临床上值得推广。

Objective To investigate the clinical effect of Marvelonon perimenopausal dysfunctional uterine bleeding. Methods Select the age 40-53 year old appearance ofperimenopausal dysfunctional uterine bleeding of 100 women of childbearing age. The blind were randomly divided into the observation group and the control groupmethod, 50 cases in each group. The observation group and curettage fifth days after the start of Marvelon, begin to take 1 tablets eachtime, every 8 h 1 times, after the cessation of blood every 3 days and decreasing 1/3 dose,to maintain the volume of 1 pieces of/d, a total of 21 days, fifth days after stopping drug withdrawal bleedingbegan to take periodic drug; control group and curettagefifteenth days after the start of oral medroxyprogesterone acetate tablets, 10 mg/d, and even served fifteenth daysafter withdrawal of 10d. withdrawal bleeding began to takeperiodic drug; two of each suit 3 cycle group. Results The observation group after taking the vaginal bleedingcontrol time and complete hemostasis time significantly shorter than the control group, in treatment effect, total effective rate of observation group 90%, contrast group48%, observation group was significantly better than the control group. Conclusion Conclusion Marvelon on perimenopausal dysfunctional uterine bleeding effect is better than the second half cycleof progesterone treatment of perimenopausal dysfunctional uterine bleeding effect, is worth popularizingin clinic.

目的 通过比较治疗组服药前、后骨密度及骨代谢指标的变化情况,并将治疗组、对照组分别作对比,观察壮骨颗粒治疗绝经后女性骨量减少及骨质疏松、改善其骨代谢的临床疗效。方法 将研究对象随机分为两组,治疗组服用壮骨颗粒＋迪巧,对照组只服用迪巧。结果 壮骨颗粒组治疗后血清中的PINP、β-Crosslaps及N-MID下降(P＜0.05);与治疗前相比,腰椎(L2-L4)BMD提高(P＜0.05);壮骨颗粒能改善绝经后女性骨代谢及提高骨密度的效果优于迪巧组。结论 壮骨颗粒是治疗绝经后女性骨量减少及骨质疏松、提高骨量、改善骨代谢情况的安全有效药物。