目的 探究肺炎支原体（MP）感染大叶性肺炎患儿常规通气、脉冲振荡肺功能特点。方法 将2022年5月—2023年5月广州市妇女儿童医疗中心收治的90例MP感染大叶性肺炎患儿为观察组,通气体检健康儿童50例为对照组,依据病变将累及多肺叶作为观察A组（10例）,累及单肺叶作为观察B组（80例）。均接受常规通气与脉冲振荡肺功能测定,观察测定结果,以此为基础,分析肺功能特点。结果 观察组各常规通气肺功能指标测定结果均低于对照组健康儿童,差异有统计学意义（P<0.05）。观察组R5、R20的实测值/预计值高于对照组,X5实测值低于对照组,差异有统计学意义（P<0.05）。气道阻力指标与肺功能呈负相关关系（P<0.05）。观察组两组最大肺活量（VCMAX）、呼气流量峰值（PEF）、用力肺活量（FVC）75%、FVC50%、FVC25%的实测值/预计值差异无统计学意义,观察A组患儿FVC、FEV₁的实测值/预计值低于观察B组患儿,差异有统计学意义（P<0.05）。两组患儿脉冲振荡肺功能对比差异无统计学意义（P>0.05）。90例患儿中,常规通气异常患儿12例,患儿治疗前后VCMAX、FVC75%、FVC50%的实测值/预计值差异无统计学意义,患儿治疗前FVC、FEV₁、PEF、FVC25%的实测值/预计值均低于治疗后,差异有统计学意义（P<0.05）。结论 常规通气与脉冲振荡相关性良好,气道阻力对VCMAX及FVC具有反向作用,MP感染大叶性肺炎主要表现为小气道通气功能受损,气道阻力升高。

Objective To explore the lung function characteristics of routine ventilation and pulse oscillation in children with lobar pneumonia infected with Mycoplasma pneumoniae（MP）．Methods Ninety children with MP infected lobar pneumonia admitted to Guangzhou Women and Children's Medical Center from May 2022 to May 2023 were selected as the observation group,and 50 healthy children undergoing ventilation examination were selected as the control group．Based on the lesion,cases with multi lobar involvement were selected as the observation group A（10 cases）,cases with single lobar involvement were selected as the observation group B（80 cases）．All patients underwent routine ventilation and pulse oscillation received pulmonary function measurement,and the measurement results were observed．Based on this,the characteristics of lung function were analyzed．Results The results of routine ventilation lung function indicators in the observation group were lower than those in the control group,and the difference was statistically significant（P<0.05）．The measured/expected values of R5 and R20 in the observation group were higher than those in the control group,while the measured values of X5 were lower than those in the control group,with statistical significance（P<0.05）．There is a negative correlation between airway resistance indicators and lung function（P<0.05）．The measured/predicted values of vital capacity max（VCMAX）,peak expiratory flow（PEF）,forced vital capacity（FVC）75%,FVC50%,and FVC25% in the observation group were not with statistically significant difference．The measured/predicted values of FVC and FEV₁ in the observation group A were lower than those in the observation group B,and the difference was statistically significant（P<0.05）．There was no statistically significant difference in pulmonary function between the two groups of pediatric patients with pulse oscillation（P>0.05）．Among the 90 patients,12 had abnormal conventional ventilation．The measured/predicted values of VCMAX,FVC75%,and FVC50% before and after treatment were not significantly different．The measured/predicted values of FVC,FEV₁,PEF,and FVC25% before treatment were lower than those after treatment,and the difference was statistically significant（P<0.05）．Conclusions There is good correlation between conventional ventilation and pulse oscillation．Airway resistance has a reverse effect on VCMAX and FVC．MP infected lobar pneumonia is mainly characterized by impaired small airway ventilation function and increased airway resistance．

目的 本文对广州市妇女儿童医疗中心2014—2016年院间转运的神经系统患儿进行流行病学分析,探讨危重神经系统疾病患儿转运的安全性。方法 将2014年1月—2016年12月年广州市妇女儿童医疗中心神经系统疾病危重患儿转运986例进行回顾性分析。结果 986例神经系统疾病危重患儿的转运,转运途中无1例死亡,转运男女比例为1.91∶1,转诊患儿的年龄分布主要集中在1月～2岁11个月,占56.64%;转诊患儿无季节性差异,93.96%的疾病是“抽搐查因”和“颅内感染”,81.12%转诊患儿转运半径在150公里以内。结论 由于基层医院受医疗技术、医疗设备的限制,神经系统疾病危重患儿有必要转诊到三级医院进行救治;根据转运神经系统疾病危重患儿的流行病学特征,转运中心应该采取应急措施达到及时安全有效的院间转运。

Objective Children with nervous system diseases needed transfer between hospitals in Guangzhou women and children medical center from 2014 to 2016 was analyzed by the epidemiological method. To explore the safety of the critically ill children with transshipment in diseases of the nervous system. Methods 986 children with nervous system diseases needed transfer between hospitals was given a retrospective analysis. Results In 986 cases transit there were no deaths, male to female ratiowas 1.91∶1; referral of children's age distribution was mainly concentrates in 1 months to 2 years 11 months old, accounting for 56.64%; there was seasonal difference with referral children; 93.96% of the disease were “tic check for” and “intracranial infection”; 81.12% of children of the referral transfer within 150 km radius. Conclusion Critically ill children with nervous system disease referred to a tertiary hospital for treatment is necessary because of the grass-roots hospitals restricted by medical technology and equipments. According to the epidemiological characteristics of transport of critically ill children with nervous system disease, transit center should take emergency measures to arrive timely, safe and effective among hospitals.