目的 了解惠州市早产儿视网膜病变的发病状况,并探讨相关危险因素。方法 回顾分析我院在2015年1月—2015年9月776例(1552只眼)早产儿和低体重儿的眼病筛查资料。结果 776例早产儿中,发现各期ROP共27例,检出率3.479%,其中包括1期11例(18只眼),2期11例(22只眼),3期2例(4只眼),AP-ROP3例(6只眼)。统计学分析显示,ROP组和无ROP组在出生胎龄、出生体重、吸氧史间比较,差异有统计学意义,提示早产、低出生体重与ROP的发生密切相关。结论 惠州地区ROP发病率3.479%,出生体重、出生胎龄、吸氧史及宫内缺氧、母体慢性高血压合并妊娠等孕期母体因素都是影响其发生的高危因素。

Objective To study the incidence of retinopathy of prematurity and to analyse the risk factors for ROP. Methods A retrospective analysis was conducted on 776 premature children from January 2015 to September 2015. Results In the 776 premature babies examinaion, 26 cases(54 eyes, 3.479%)developed ROP, including 11 cases (18 eyes) suffering from stage 1,11 cases (22 eyes) from stage 2,2 cases (4 eyes) from stage 3,3cases (6 eyes) from AP-ROP. The results of statistical analysis showed that gestational age, birth weight and oxygen therapy were significantly to ROP. Clinical analysis indicated that prematurity, low birth weight and oxygen therapy were closely related to the occurrence of ROP. Conclusion The incidence of ROP in Huizhou city is 3.479%. The gestational age, birth weight ,intrauterine hypoxia, and maternal prenatal factors such as chronic hypertension with pregnancy are the high risk factors of ROP.

目的 了解惠州市新生儿眼病的发病状况,探讨新生儿眼病筛查的临床模式。方法 回顾分析我院在2014年1月—2015年3月950例(1900只眼)高危新生儿的眼病筛查资料。结果 950例(1900只眼)新生儿中,检查出新生儿眼病10种,共200例,检出率21.05%;其中家族性渗出性视网膜病变(FEVR)5例(0.526%)、永存原始玻璃体增生症(PHPV)1例(0.105%)、先天性白内障1例(0.105%)、视网膜出血55例(5.789%)、生理性大视杯3例(0.316%)、新生儿鼻泪管阻塞5例(0.526%)、新生儿结膜炎100例(10.53%)、皮样脂肪瘤2例(0.211%)、新生儿泪囊黏液囊肿2例(0.211%)、早产儿视网膜病变26例(2.737%)。结论 新生儿眼病在临床中并不少见,而且部分眼病是可以早期筛查、早期治疗以避免盲的。

Objective To study the incidence of newborn eye diseases and to explore the clinical strategies for the screening of newborn ocular diseases. Methods A retrospective analysis was conducted on 950 newborns from January 2014 to March 2015. Results Among the 950 newborns who were enrolled the screening program,10 different eye diseases(involving 200 cases)were detected,with a prevalence of 21.05%. The eye diseases included familial exudative vitreoretinopathy in 5 cases(0.526%),persistent hyperplastic primary vitreous in 1 case(0.105%),congenital cataract in 1 case(0.105%),retinal hemorrhage in 55 cases(5.789%), physiologic large cup in 3 cases(0.316%),congenital lacrimal duct obstruction in 5 cases(0.526%),neonatal conjunctivitis in 100 cases(10.53%),dermolipoma in 2 cases(0.211%),congenital lacrimal sac mucocele in 2 cases(0.211%),retinopathy of prematurity in 26 cases(2.737%). Conclusion Neonatal eye diseases are not uncomon in clinical, and a part of the eye diseases can be early screening and early treatment to avoid blindness.