论著

某净水公司职工脂肪肝检出情况及影响因素分析

Prevalence of fatty liver disease and influencing factors among employees in a water purification company

:1456-1463
 
目的 了解广州市某净水公司职工脂肪肝检出情况,并分析影响因素。方法 选取2023年广州市某净水公司参加职业健康检查的职工为研究对象,收集研究对象的一般情况、个人史、职业史、身体质量指数(BMI)、血压、血生化指标、肝脏彩超等资料。对该人群脂肪肝的患病情况进行描述性分析,对脂肪肝的影响因素进行单因素及多因素Logistic回归分析。结果 共收集研究对象1 217人,检出脂肪肝543例,检出率为44.62%。单因素分析结果表明,脂肪肝的发生与性别、年龄、体质量指数、高血压相关(P<0.05)。接触硫化氢、氨的职工脂肪肝检出率高于非接触者(P<0.05),且职工工龄越长,脂肪肝检出率越高(P<0.05)。患脂肪肝职工的肝功能、脂代谢、血糖及尿酸水平高于非脂肪肝者(P<0.05)。多因素Logistic回归分析提示,年龄、体质量指数、肝功能异常、脂代谢异常、高血糖、高尿酸是脂肪肝的影响因素(P<0.05)。结论 广州市某净水公司职工的脂肪肝检出率较高,脂肪肝的发生主要与年龄、体质量指数、肝功能异常、脂代谢异常、高血糖、高尿酸等因素相关。
Objective To investigate the prevalence of fatty liver disease and influencing factors among employees of a water purification company in Guangzhou.Methods Employees of a water purification company in Guangzhou who participated in occupational health examinations in 2023 were selected as the study subjects.The subjects' general conditions,personal history,occupational history,BMI,blood pressure,blood biochemical indicators,and liver ultrasound images were collected.Descriptive analysis was used to analyze the prevalence of fatty liver disease in this population.The influencing factors of fatty liver were analyzed by single factor and multiple factor Logistic regression.Results A total of 1 217 subjects were included in this study,and 543 were diagnosed as fatty liver disease,with a detection rate of 44.62%.The results of single factor analysis showed that the occurrence of fatty liver was closely related to gender,age,BMI and hypertension(P<0.05).The analysis of occupational hazard factors showed that,the detection rate of fatty liver disease was higher in people exposed to hydrogen sulfide and ammonia compared to non-exposed individuals(P<0.05).The longer the working years,the higher the detection rate of fatty liver(P<0.05).The levels of liver function,lipid metabolism,blood glucose and uric acid in workers with fatty liver were higher than those in workers without fatty liver(P<0.05).Multivariate Logistic regression analysis showed that age,BMI,abnormal liver function,abnormal lipid metabolism,high blood glucose levels and hyperuricemia were independent influencing factors for fatty liver disease(P<0.05).Conclusions The detection rate of fatty liver disease among employees of a water purification company in Guangzhou is high,and the occurrence of fatty liver disease is mainly related to factors such as age,BMI,abnormal liver function,abnormal lipid metabolism,high sugar levels and hyperuricemia.
临床诊疗

探究尿毒症继发性甲状旁腺功能亢进经甲状旁腺切除术治疗效果及安全性分析

:129-132
 
目的 探究尿毒症继发性甲状旁腺功能亢进经甲状旁腺切除术治疗效果及安全性分析。方法 选取2017年6月—2019年5月于我院就诊的90例尿毒症继发性甲状旁腺功能亢进患者为研究对象,随机分为对照组与观察组,两组各45例。均采取同一药物治疗,对照组行次全切除治疗,观察组行甲状旁腺全切除术+前臂移植术。对比分析两组治疗效果、血生化指标及并发症。结果 观察组疗效优于对照组(P<0.05);观察组术后1周、1个月钙、iPTH、磷、钙磷乘积及ALP水平均低于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05)。结论 甲状旁腺全切除+前臂移植治疗尿毒症继发性甲状旁腺功能亢进疗效显著,并发症风险低,值得推广。
论著

小剂量罗红霉素联合桉柠蒎肠溶软胶囊治疗慢性鼻窦炎的疗效观察

Clinical observation on ELP enteric soft capsule combined with small dose roxithromycin treating chronic sinusitis

:78-80
 
目的 探讨口服小剂量罗红霉素联合桉柠蒎肠溶软胶囊治疗慢性鼻窦炎的疗效。方法 将96例慢性鼻窦炎患者随机分为治疗组和对照组,每组48人,对照组给予口服小剂量罗红霉素片 150 mg,2次/天,治疗组在口服相同剂量罗红霉素的基础上加用桉柠蒎肠溶软胶囊胶囊300 mg,2次/天。治疗1个月与3个月后两组疗效进行比较。结果 1个月和3个月后治疗组疗效优于对照组,两组之间差异有统计学意义(P<0.05 )。结论 小剂量罗红霉素联合桉柠蒎肠溶软胶囊治疗慢性鼻窦炎临床效果显著,且用药方便,值得向基层医院推广。
Objective To observe the effect of eucalyptol limonene and pineneELP enteric soft capsule combined with roxithromycin on chronic sinusitis in clinical treatment. Methods 96 patients with chronic sinusitis were randomly divided into two groups: 48 cases were treated with roxithromycin(150 mg twice a day),and 48 cases were treated with roxithromycin combined with ELP enteric soft capsule (300 mg twice a day). The symptoms of patients were evaluated after 1 and 3 months treatment. Results The difference was significant between the group treated with ELP enteric soft capsule combined with roxithromycin and the group treated with roxithromycin alone after 1 month and 3 months (P<0.05). Conclusion ELP enteric soft capsule combined with roxithromycin treating chronic sinusitis not only has evident clinical effect,but also is easy,which is worth recommending to the primary hospital.
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