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肝胆胰外科中吲哚菁绿荧光成像技术的应用研究进展

Progress of indocyanine green fluorescence imaging in hepatobiliary and pancreatic surgery

:133-143
 
        吲哚菁绿(ICG)荧光成像技术基于ICG独特的代谢特性及近红外光激发特性, 通过动态荧光显影成像为手术提供精准导航, 其在肝胆胰外科领域展现出重要的应用价值。随着多版国内外指南的迭代更新, ICG荧光导航技术已被确立为肝胆胰外科手术的重要辅助手段, 其安全性和有效性得到充分验证。文章就ICG荧光成像技术的原理、在肝胆胰外科应用中的现状、在临床应用中面临的问题以及其应用展望展开综述。
       Based on the unique metabolic properties and near-infrared light excitation characteristics of indocyanine green(ICG), the ICG fluorescence imaging technology provides dynamic fluorescence imaging for precise surgical navigation.This technology has demonstrated significant value in hepatobiliary and pancreatic surgery.With iterative updates to international and domestic guidelines, ICG-based fluorescence navigation has been established as an essential adjunctive tool in hepatopancreaticobiliary procedures, with its safety and efficacy validated through extensive clinical research.This review systematically explores the underlying principles of ICG fluorescence imaging, its current applications in liver, biliary, and pancreatic surgeries, the challenges encountered in clinical practice, and future directions for technological optimization and clinical translation
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机械通气危重患者卧位与中心静脉压的关系研究

The relationship between lying angle and central venous pressure in critically ill patients undergoing mechanical ventilation

:804-808
 
       目的   探讨机械通气危重患者卧位与中心静脉压(CVP)的关系。方法   选取2022年1月—2024年1月开封市中医院收治的110例机械通气危重患者作为研究对象进行回顾性分析,依照患者不同卧床体位进行分组,分为平卧位组(n=20)、30°卧位组(n=30)、45°卧位组(n=40)、60°卧位组(n=20),分析机械通气危重患者卧位与中心静脉压的关系。结果   不同体位患者呼吸频率(RR)、心率(HR)、血氧饱和度(SpO2)、平均动脉压(MAP)比较差异无统计学意义(P>0.05),不同体位患者CVP水平比较差异有统计学意义,平卧位组更高(P<0.05);Spearman相关分析结果表明,RR、HR、SpO2、MAP与体位无相关性(P>0.05),CVP与体位角度呈负相关(P<0.05);体位一直无变化的患者5 min、10 min CVP差值比较差异无统计学意义(P>0.05),5 min内变化体位与5~10 min变化体位患者CVP差值有所变化(P<0.05);CVP水平可随着体位角度增加而降低,随着呼气末正压(PEEP)水平升高而升高(P<0.05)。结论   机械通气危重患者CVP可随着体位及PEEP水平变化而发生改变,因此针对患者监测CVP过程中可尽量让患者保持平卧位5 min后,且确保每次监测过程中PEEP稳定时进行CVP监测,可在监测后再对患者进行体位调整,确保CVP数据准确的同时,提升患者舒适度。
       Objective  To explore the relationship between lying angle and central venous pressure(CVP)in critically ill patients undergoing mechanical ventilation.Methods  A  retrospective analysis was conducted on 110 critically ill patients with mechanical ventilation admitted to the hospital from January 2022 to January 2024.The patients were divided into three groups based on their different bed positions:supine position group(n=20),30° lying angle group(n=30),45° lying angle groupn=40),and 60° lying angle group(n=20).The relationship between CVP and lying angle of patients were compared.Results  There was no significant difference in respiratory rate(RR),heart rate(HR),blood oxygen saturation(SpO2),and mean arterial pressure(MAP)between patients in different lying angle(P>0.05),and there was a significant difference in CVP among patients in different lying angle.The supine position group had a significantly higher CVP(P<0.05).The Spearman correlation analysis results showed that RR,HR,SpO2,MAP were not significantly correlated with lying angle(P>0.05),while CVP was negatively correlated with body lying angle(P<0.05).There was no significant difference(P>0.05)in CVP between 5 minutes and 10 minutes in patients with no changes in lying angle,while patients with changes in lying angle within 5 minutes and those between 5 minutes and 10 minutes showed significant changes(P<0.05).CVP levels decreased with increasing lying angle and increased with increasing PEEP level(P<0.05).Conclusions  The CVP of critically ill patients undergoing mechanical ventilation can change with lying angle and PEEP level.Therefore,during the monitoring of CVP for patients,it is advisable to keep them in a supine position for 5 minutes and ensure that PEEP is monitored simultaneously during each monitoring process.After monitoring,the patient’s posture can be adjusted to ensure accurate CVP data and improve patient’s comfort level.
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