论著

冠心病患者心脏康复参与意愿的调查分析

Investigation and analysis of participation willingness of cardiac rehabilitation in coronary heart disease patients

:723-729
 
目的 研究影响冠状动脉粥样硬化性心脏病(冠心病)患者参与心脏康复意愿的因素及干预措施。方法 选取高州市人民医院 2021年1月—2022年3月收治的624例冠心病患者为研究对象,使用自行设计的调查问卷心脏康复参与意愿调查表及西雅图心绞痛量表对患者进行调查评估,分析冠心病患者心脏康复参与意愿现状及其影响因素。结果 624例冠心病患者中,162例愿意参加(25.96%),126例希望参加(20.19%),66例计划参加(10.58%);单因素分析显示影响冠心病患者心脏康复参与意愿的因素主要包括社会支持、文化水平、娱乐活动、呼吸困难及心绞痛,社会支持方面,主观支持、客观支持、支持利用度得分分别为(2.32±0.41)(2.99±0.74)(2.58±0.95)分,组间比较差异有统计学意义(F=53.428,P<0.001);文化水平方面,初中及以下、高中及中专、大专及以上得分分别为(2.35±0.18)(2.61±0.90)(3.09±0.63)分,组间比较差异有统计学意义(F=29.947,P<0.001);娱乐活动方面,无、偏少、正常得分分别为(2.60±0.12)(2.88±0.29)(3.13±0.72)分,组间比较差异有统计学意义(F=44.903,P<0.001);呼吸困难方面,≥1次/天、≥1次/周、<1次/月或无得分分别为(2.09±0.84)(2.31±0.70)(3.06±0.53)分,组间比较差异有统计学意义(F=116.082,P<0.001);心绞痛方面,≥1次/天、≥1次/周、<1次/月或无得分分别为(2.51±0.33)(2.82±0.76)(3.15±0.87)分,组间比较差异有统计学意义(F=16.442,P<0.001);多因素分析显示影响冠心病患者心脏康复参与意愿的独立影响因素主要包括文化程度、娱乐活动、呼吸困难及社会支持,结果有统计学意义(P<0.05)。结论 文化程度、娱乐活动、呼吸困难及社会支持等因素是导致冠心病患者心脏康复参与意愿较低的主要原因,临床上应对此予以重视,并采取康复教育、实施延续性护理、建立支持环境等措施,促使冠心病患者积极参与到心脏康复中,从而有效改善其预后。
Objective To study the factors and intervention measures that affect the willingness of coronary heart disease patients to participate in cardiac rehabilitation.Methods A total of 624 patients with coronary heart disease admitted to Gaozhou People's Hospital from January 2021 to March 2022 were selected as the research subjects.A self-designed survey questionnaire on willingness to participate in cardiac rehabilitation and the Seattle Angina Pectoris Scale were used to investigate and evaluate the patients.The current status and influencing factors of willingness to participate in cardiac rehabilitation in coronary heart disease patients were analyzed.Results Among 624 patients with coronary heart disease,162 were willing to participate(25.96%),126 hoped to participate(20.19%),and 66 planned to participate(10.58%).Uunivariate analysis showed that the main factors affecting the willingness of coronary heart disease patients to participate in cardiac rehabilitation included social support,education level,entertainment activities,breathing difficulties,and angina.In terms of social support,subjective support,objective support,and support utilization scores were(2.32±0.41)points,(2.99±0.74)points,and(2.58±0.95)points,respectively,with statistically significant differences(F=53.428,P<0.001).In terms of education level,the scores for middle school and below,high school and vocational school,college and above were(2.35±0.18)points,(2.61±0.90)points,and(3.09±0.63)points,respectively,with statistically significant differences(F=29.947,P<0.001).In terms of entertainment activities,the scores for none,less and normal were(2.60±0.12)points,(2.88±0.29)points,and(3.13±0.72)points,respectively,with statistically significant differences(F=44.903,P<0.001).In terms of breathing difficulties,the scores for ≥1 time/day,≥1 time/week,<1 time/month,or no were(2.09±0.84)points,(2.31±0.70)points,and(3.06±0.53)points,respectively,with statistical significance(F=116.082,P<0.001).In terms of angina,the scores for ≥1 time/day,≥1 time/week,<1 time/month,or no were(2.51±0.33)points,(2.82±0.76)points,and(3.15±0.87)points,respectively,with statistical significance(F=16.442,P<0.001).Multivariate analysis showed that the independent influencing factors on the willingness of coronary heart disease patients to participate in cardiac rehabilitation mainly include education level,entertainment activities,breathing difficulties,and social support,and the results were statistically significant(P<0.05).Conclusions Education level,entertainment activities,breathing difficulties,and social support are the main reasons for the low willingness of coronary heart disease patients to participate in cardiac rehabilitation.Clinical attention should be paid to this and measures such as rehabilitation education,implementation of continuity of care,and establishment of a supportive environment should be taken to encourage coronary heart disease patients to actively participate in cardiac rehabilitation and effectively improve their prognosis.
论著

真武汤联合八段锦对老年冠心病患者心肺运动功能及生存质量的影响

Clinical effects of Zhenwu Decoction combined with Baduanjin Qigong on the cardiopulmonary function and quality of life in older adults with coronary heart disease

:1470-1475
 
目的 探讨真武汤联合八段锦在老年冠状动脉粥样硬化性心脏病(冠心病)患者中的应用效果。方法 将96例75岁以上冠心病患者按照随机数字表法分为对照组与干预组,每组各48例。在12周的临床研究期间,对照组用规范的冠心病二级预防药物治疗;干预组在规范的冠心病二级预防药物治疗基础上,增加真武汤以及八段锦运动处方。结果 治疗后干预组中医临床疗效(P=0.023)和中医证候积分(P<0.001)均优于对照组。两组患者的心肺运动试验指标均有改善,且干预组在升高峰值摄氧量(Peak VO2,P=0.005)、最大摄氧量(VO2max,P=0.001)、氧脉搏(VO2/HR,P=0.002)和无氧阈值时最大代谢当量(MET,P=0.001),以及降低无氧阈值(AT,P<0.001)和二氧化碳通气当量(VE/VCO2,P=0.020)方面比对照组更明显。两组患者在36项简明健康状态调查表(SF-36)评分的8个维度中评分均有所升高,其中在生理机能(P=0.001)、生理职能(P<0.001)、一般健康状况(P=0.018)、精力(P=0.007)、社会职能(P=0.010)、精神健康(P=0.004)方面,干预组效果优于对照组;而在躯体疼痛、情感职能维度改善方面,两组间结果相近,差异无统计学意义(P>0.05)。两组患者的匹兹堡睡眠质量指数(PSQI)均有所改善,且干预组效果优于对照组(P<0.001)。结论 真武汤联合八段锦能够进一步增强老年冠心病患者中医证候疗效,改善心肺运动试验Peak VO2、VO2max、VO2/HR、MET、AT、VE/VCO2等指标,并提高SF-36评分多个维度的生活质量及睡眠质量。
Objective To explore the therapeutic effects of Zhenwu Decoction combined with Baduanjin Qigong in older adults with coronary heart disease(CHD).Methods Ninety-six patients with CHD aged ≥75 years were randomly divided into a treatment group and a control group,with 48 patients in each group.Within the 12-week period,the control group received standard secondary prevention therapy for CHD,while the treatment group received Zhenwu Decoction and Baduanjin Qigong prescription,in addition to the standard treatment.Results After treatment,both groups showed improvement in the traditional Chinese medicine(TCM)clinical efficacy,TCM syndrome,SF-36 scores and Pittsburgh Sleep Quality Index(PSQI)scores;increase in Peak VO2,VO2max,VO2/HR,and metabolic equivalent(MET);and decrease in AT and VE/VCO2.However,the treatment group had a more pronounced improvement in the TCM clinical efficacy(P=0.023),TCM syndrome(P<0.001),PSQI scores(P<0.001),and cardiopulmonary exercise testing(CPET)indicators including Peak VO2(P=0.005),VO2max(P=0.001),VO2/HR(P=0.002),MET(P=0.001),AT(P<0.001)and VE/VCO2(P=0.020),compared to their control counterparts. For the SF-36 scores,in comparison to the control group,the treatment group presented better outcomes in enhancing physical functioning(P=0.001),role limitations due to physical health(P<0.001),general health(P=0.018),vitality(P=0.007),social functioning(P=0.010)and mental health(P=0.004),but not in pain or role limitations due to emotional problems.Conclusions The Zhenwu Decoction combined with Baduanjin Qigong can enhance the TCM syndrome,improve various CPET indicators such as Peak VO2、VO2max、VO2/HR、MET、AT and VE/VCO2,and elevate both quality of life and sleep quality among older adults with CHD.
论著

伊伐布雷定对冠心病合并心律失常患者心率变异性的影响及对心房颤动的防治效果

Effect of ivabradine on heart rate variability and prevention and treatment of atrial fibrillation in patients with arrhythmia in coronary heart disease

:83-88
 
目的 观察伊伐布雷定对冠状动脉粥样硬化性心脏病(CHD,以下简称:冠心病)合并心律失常患者心率变异性(HRV)的影响,及对心房颤动(AF)的防治效果。方法 本文为前瞻性研究,病例纳入时间为2021年1月—2023年1月,研究对象为焦作市第二人民医院收治的125例CHD合并心律失常患者,采用随机数字表法对入组患者进行分组,分别列为常规组(62例)和联合组(63例),常规组予常规药物治疗,联合组在常规药物治疗基础上联合伊伐布雷定治疗,比较2组患者治疗前后的HRV指标、血管内皮功能指标、心功能指标改善情况、心房颤动发生率及用药安全性。结果 治疗后,联合组24 h窦性心律RR间期标准差为(88.25±10.36)ms,24 h相邻正常RR间期差值均方根为(50.25±10.61)ms,24 h相邻正常RR间期差值>50 ms百分比为(12.04±3.41)%,均高于常规组[(81.44±10.77)ms、(43.28±10.71)ms、(10.77±3.08)%],组间比较差异具有统计学意义(P<0.05)。治疗后,联合组的血流介导下血管扩张程度为(12.33±3.27)%,硝酸甘油介导下血管内皮舒张程度为(9.83±2.21)%,均高于常规组[(10.25±3.23)%、(8.14±2.03)%]。AF发生率为4.76%(3/63),低于常规组16.13%(10/62),差异具有统计学意义(P<0.05)。治疗后,联合组的左室射血分数为(55.35±10.27)%,高于常规组(48.45±10.61)%,左室舒张末期内径为(40.24±10.37)mm,左室后壁厚度为(9.22±2.06)mm,均低于常规组[(46.33±10.28)mm、(10.88±2.46)mm],差异具有统计学意义(P<0.05)。治疗后,联合组的药物相关不良反应发生率为7.94%(5/63),略高于常规组6.45%(4/62),组间比较差异无统计学意义(P>0.05)。结论 伊伐布雷定联合常规药物治疗CHD合并心律失常能有效改善患者HRV指标、血管内皮功能及心功能,降低AF发生率,且未增加药物不良反应发生风险。
Objective To observe the effect of ivabradine on heart rate variability(HRV)in coronary heart disease(CHD)patients with arrhythmia and its preventive and therapeutic effects on atrial fibrillation(AF).Methods This is a prospective cohort study.The 125 CHD patients with arrhythmia were included from January 2021 to January 2023 and divided into the conventional group(62 cases)and the combined group(63 cases)by random number table.The conventional group was treated with conventional drugs,and the combined group was treated with ivabradine additionally.The HRV index,vascular endothelial function index,improvement of cardiac function indicators,incidence of AF and medication safety were compared.Results After treatment,the standard deviation of normal RR intervals in 24 h of the combination group was(88.25±10.36)ms,root mean square of successive RR interval differences in 24 h was(50.25±10.61)ms,and successive RR interval differences>50 ms was(12.04±3.41)%.Compared with the conventional group [(81.44±10.77)ms,(43.28±10.71)ms and(10.77±3.08)%],the above indicators were all higher(P<0.05).After treatment,the flow-mediated dilation and nitrite-mediated dilation of the combination group were(12.33±3.27)% and(9.83±2.21)%,respectively.Compared with the conventional group(10.25±3.23)% and(8.14±2.03)%),the above indicators were higher.The incidence of AF was 4.76%(3/63),which was lower(P<0.05)than the conventional group of 16.13%(10/62).After treatment,the left ventricular ejection fraction of the combination group was(55.35±10.27)%,which was higher than that of the conventional group(48.45±10.61)%.The left ventricular diastolic diameter was(40.24±10.37)mm and the left ventricular posterior wall thickness was(9.22±2.06)mm.Compared with the conventional group [(46.33±10.28)mm,(10.88±2.46)mm],the above indicators were all lower(P<0.05).After treatment,the incidence of drug-related side effects in the combination group was 7.94%(5/63),which was similar to 6.45%(4/62)in the conventional group(P>0.05).Conclusions The combination of ivabradine and conventional drugs in the treatment of CHD complicated with arrhythmia can effectively improve HRV indicators in patients,promote the recovery of vascular endothelial cell function and cardiac function,reduce the incidence of AF,and do not significantly increase the risk of drug side effects.
临床诊疗

冠心病介入治疗中出现心血管迷走神经反射的原因及防治措施

:131-134
 
目的 对冠心病治疗过程中出现迷走神经反射的原因进行分析探讨,并进行高效防治措施的总结。方法 本研究采用现况研究进行调查。本研究以在本院2021年1月—2021年3月就诊并临床诊断为冠心病的患者作为研究对象,经过纳入、排除标准筛选,共挑选出240名患者作为研究对象。根据文献分析得知拔鞘管可能是影响冠心病介入治疗过程中出现迷走神经反射的重要原因,因此将研究对象分为2组,实验组130人,对照组110人。对2组患者进行冠状动脉腔内血管成形术+支架置入术。实验组在患者进行鞘管拔出时进行局部麻醉;对照组则按照常规方法对鞘管进行拔出,分析2组患者迷走神经发生反射的几率,运用统计学软件进行数据分析对比。结果 根据数据分析结果可知,2组患者出现迷走神经反射的几率并不相同,通过差异性分析可知2组数据的差异具有统计学意义,且观察组发生率低于对照组(P<0.05)。结论 建议在临床上对冠心病进行介入治疗时,拔除鞘管的过程应该加入合理的干预,以减少患者出现迷走神经反射的几率,增强患者预后。
临床诊疗

吸入和静脉麻醉对老年冠心病患者术后不良心血管事件的影响

Effects of inhalation and intravenous anesthesia on postoperative adverse cardiovascular events in elderly patients with coronary heart disease

:133-135
 
目的 探究不同麻醉方式对患有冠心病的老年患者外科介入不良心血管事件作用的对比。方法 选取2020年1月—2021年1月,我院确诊的冠心病患者,且无心脏外科干预手术80 例,随机分为研究干预组(n=40)和空白对照组(n=40),研究组采用2%的七氟醚,对照组用丙泊酚联合瑞芬太尼,维持麻醉血浆靶浓度在3.0~6.0 mg/L 之间,方式为静脉泵注;分析2组病人外科术后负性心脏情况控制影响; 结果 研究组和对照组患者的肌酸激酶存在差异,同时心脏肌钙蛋白T的高低也存在差异(P均<0.05);研究组在术后的负性心血管情况发病率均低于空白对照组,其中研究组的心源性猝死、心律紊乱不齐和心脏源性的休克等的病变率要远低于对照组,统计学差异存在意义(P均<0.05);而其中研究组的心力衰竭与对照组相比,差异不具有统计学意义(P>0.05)。结论 相比于静脉麻醉,吸入式麻醉能够趋好性降低非心脏手术术后负性心脏相关风险的发生率,该研究对于临床实践有一定的参考意义和实践可操作性,可以考虑普及推广。
论著

心脉通治疗冠心病临床随机对照试验的系统评价

Systematic review of clinical randomized controlled trials of Xinmaitong in the treatment of coronary heart disease

:118-124
 
目的 系统评价心脉通治疗冠心病的临床疗效及其安全性。方法 2名研究者独立系统地检索心脉通治疗冠心病的文献,其中包括维普中文科技期刊全文数据库(VIP)、PubMed 电子期刊全文数据库、中国学术期刊全文数据库(CNKI)、The Cochrane Library 数据库、万方数据库等6个数据库。同时运用Review Manager 5.4 软件进行本研究的数据处理。结果 最终共纳入8篇文献,共计985名心脉通治疗冠心病患者。治疗前后的临床疗效、发作频率、血脂水平的Meta分析结果显示心脉通组优于常规治疗组。有3项纳入试验报告不良反应。结论 心脉通治疗冠心病的临床疗效优于常规治疗。心脉通不仅可以降低冠心病发作频率,缩短其发作持续时间,还能调节血脂水平,在治疗冠心病方面疗效确切,值得临床参考应用。
Objective To systematically evaluate the clinical efficacy and safety of Xinmaitong in the treatment of coronary heart disease (CHD). Methods Two researchers searched the literatures of Xinmaitong in the treatment of coronary heart disease independently and systematically, including VIP Chinese Sci-tech Journal full-text Database (VIP), PubMed Electronic Journal full-text Database, Chinese Academic Journal full-text Database (CNKI), The Cochrane Library Database and Wanfang Database. At the same time, Review Manager 5.4 software was used to process the data of this study. Results A total of 8 articles were included, and a total of 985 patients with coronary heart disease were treated with Xinmaitong. The results of Meta analysis of clinical efficacy, attack frequency and blood lipids level before and after treatment showed that Xinmaitong group was better than routine treatment group. Three items were included in the report of adverse reactions. Conclusions The clinical effect of Xinmaitong in the treatment of coronary heart disease was better than that of routine treatment. Xinmaitong can not only reduce the frequency and duration of coronary heart disease attack, but also regulate blood lipids level. Xinmaitong was effective in the treatment of coronary heart disease and is worthy of clinical reference.
论著

血清胆红素与尿酸检验诊断冠心病的准确性

The accuracy of serum bilirubin and uric acid detection in the diagnosis of coronary heart disease

:26-29
 
目的 探究冠心病患者实施血清胆红素与尿酸检验的临床诊断价值。方法 遴选时段2020年6月—2021年6月内100例冠心病患者记观察组,另择取同时段健康体检对象100例记对照组,检测血清胆红素、尿酸水平并2组相对比,同时观察组患者根据冠脉狭窄程度(Gensini法)分组为A、B、C、D组,比较冠脉不同狭窄程度分级下上述指标的变化;评估对比血清胆红素、尿酸单项指标检验与联合检验对冠心病患者的诊断效能。结果 观察组较对照组血清胆红素(总胆红素、直接胆红素、间接胆红素)水平更低,尿酸水平更高,对比有统计学差异(P<0.05);随着冠脉狭窄程度越严重患者血清胆红素水平呈下降趋势,尿酸水平呈升高趋势,且4组组间比较均差异有统计学意义(P<0.05);冠心病患者血清胆红素联合尿酸检验的诊断敏感度96.00%、特异度95.00%均高于单项检验敏感度及特异度(P<0.05)。结论 血清胆红素与尿酸水平可作为冠心病患者诊断的敏感性指标,其与冠心病的发生及发展密切相关,可反映患者病情严重程度,且联合检验诊断价值更高。
Objective To explore the clinical diagnostic value of serum bilirubin and uric acid detection in patients with coronary heart disease. Methods A total of 100 patients with coronary heart disease from June 2020 to June 2021 were selected as the observation group, and another 100 healthy subjects in the same period were selected as control group. Serum bilirubin and uric acid levels were detected and compared between the two groups. Meanwhile, the patients in the observation group were divided into groups A, B, C and D according to the degree of coronary artery stenosis (Gensini method). The changes of the above indexes were compared among different grades of coronary stenosis. And the diagnostic efficacy of each single detection and combined detection of serum bilirubin and uric acid in patients with coronary heart disease were evaluated and compared. Results Compared with the control group, the serum bilirubin (total bilirubin, direct bilirubin, indirect bilirubin) level of the observation group was lower, and the uric acid level was higher, with statistical differences (P<0.05). With the increased severity of coronary artery stenosis, the serum bilirubin level of patients showed a downward trend, while the uric acid level showed an upward trend, and there were significant differences among the four groups (P<0.05). The sensitivity and specificity of serum bilirubin combined with uric acid detection in patients with coronary heart disease were 96.00% and 95.00% respectively, which were higher than those of single detection (P<0.05). Conclusions Serum bilirubin and uric acid levels can be used as sensitive indicators in the diagnosis of patients with coronary heart disease, and are closely related to the occurrence and development of coronary heart disease, which can reflect the severity of the disease, also the diagnostic value of combined detection is higher.
论著

冠心病患者血清HCY、HO-1水平及其与冠状动脉Gensini积分的相关性研究

Study of serum HCY and HO-1 levels in patients with coronary artery disease and their correlation with coronary Gensini score

:72-75
 
目的 探究冠心病患者血清同型半胱氨酸(HCY)、血红素加氧酶-1(HO-1)水平与冠状动脉Gensini积分的相关性,并对其进行分析与探讨。方法 随机选取2020年3月—2021年7月于我院心内科行冠脉造影确诊的冠心病患者108例作为观察组和同期于我院行冠脉造影排除冠心病的健康人群33例作为对照组。根据冠心病患者的Gensini积分将其分为低分组(n=42)、中分组(n=35)和高分组(n=31)。对比观察组与对照组2组研究对象血清HCY、HO-1水平差异,冠心病患者的血清HCY、HO-1水平与Gensini积分的相关性通过Pearson相关分析法分析。结果 观察组血清HCY水平高于对照组(P<0.05);观察组血清HO-1水平低于对照组血清HO-1水平(P<0.05)。高分组血清HCY水平高于中分组和低分组(P<0.05);高分组血清HO-1水平低于中分组和低分组(P<0.05)。血清HCY水平与Gensini积分呈正相关(P<0.05),血清HO-1水平与Gensini积分呈负相关(P<0.05)。结论 血清HCY、HO-1水平与冠心病患者Gensini积分密切相关。
Objective To investigate the correlation between serum homocysteine (HCY), heme oxygenase-1 (HO-1) levels and coronary Gensini score in patients with coronary artery disease. Methods One hundred and eight patients with coronary artery disease diagnosed by coronary angiography in the cardiology department of our hospital from March 2020 to July 2021 were randomly included in observation group, while 33 healthy people without coronary artery disease confirmed by coronary angiography in our hospital during the same period as the control group. The 108 patients with coronary artery disease were divided into low (n=42), medium (n=35) and high (n=31) groups by coronary Gensini score. The differences in serum HCY and HO-1 levels between observation group and control group were compared, and the correlation between serum HCY, HO-1 levels and coronary Gensini score was analyzed by Pearson correlation analysis. Results The serum HCY level of the observation group was higher than that of the control group (P<0.05); the serum HO-1 level of the observation group was lower than that of the control group (P<0.05). The serum HCY level in the high group was higher than the middle group and low group (P<0.05); the serum HO-1 level in the high group was lower than the middle group and low group (P<0.05). Serum HCY level was positively correlated with coronary Gensini score (P<0.05), and serum HO-1 level was negatively correlated with coronary Gensini score (P<0.05). Conclusions Serum HCY and HO-1 levels were closely correlated with coronary Gensini score in patients with coronary artery disease.
论著

盾叶冠心宁片与复方丹参滴丸治疗冠心病稳定型心绞痛临床疗效比较

Clinical efficacy of Dunye Guanxinning tablets and Compound Danshen dropping pills on stable angina pectoris of coronary heart disease

:70-73
 
目的 盾叶冠心宁片与复方丹参滴丸治疗冠心病稳定型心绞痛临床疗效比较。方法 选取于2017年10月—2018年10月至延安大学附属医院诊治的120例冠心病稳定型心绞痛患者。随机将所有患者分为2组,观察组患者在常规西药治疗基础上加服盾叶冠心宁片,对照组患者在常规西药治疗基础上加服复方丹参滴丸,比较两组患者治疗6个月后的临床疗效。结果 经过6个月治疗后,观察组患者的治疗有效率为66.7%,对照组患者的治疗有效率为40.0%。观察组与对照组治疗效果相比,差异有统计学意义(P<0.05)。盾叶冠心宁片治疗冠心病稳定型心绞痛的综合疗效优于复方丹参滴丸。结论 冠心病稳定型心绞痛患者在常规西药治疗不变的基础上加用盾叶冠心宁片,不仅能改善临床心绞痛症状,还能调节血脂异常及降低同型半胱氨酸水平,以及缓解患者情绪及睡眠问题,且安全性高,有较高临床应用价值。
Objective To compare the clinical efficacy of Dunye Guanxinning tablets and Compound Danshen dropping pills in the treatment of stable angina pectoris caused by coronary heart disease. Methods 120 patients with stable angina pectoris were selected from the affiliated hospital of Yan'an University from October 2017 to October 2018.All patients were randomly divided into two groups. The observation group was treated with Dunye Guanxinning tablets on the basis of conventional western medicine, while the control group was treated with Compound Danshen dropping pills on the basis of conventional western medicine. The clinical efficacy of the two groups was compared after 6 months of treatment. Results After 6 months of treatment, the effective rate was 66.7% in the observation group and 40.0% in the control group. The treatment effect of the observation group was statistical different from that of the control group (P<0.05). The comprehensive curative effect of Dunye Guanxinning tablets in treating stable angina pectoris of coronary heart disease is better than that of Compound Danshen dropping pills. Conclusion The use of Dunye Guanxinning tablets in patients with stable angina pectoris after conventional western medicine treatment may not only improve the symptoms of clinical angina pectoris, but also regulate dyslipidemia and reduce homocysteine level, as well as alleviate the patients' emotional and sleep problems. It has high safety and high clinical application value.
论著

平板运动试验阳性者冠脉造影结果预警冠心病

Results of coronary angiography in patients with positive treadmill exercise test give early warning of coronary heart disease

:28-31
 
目的 分析平板运动试验阳性患者行冠脉造影检查后结果阳性者与冠心病的高危因素的关联性,从而预警冠心病。方法 选取浙江大学医学院附属第二医院2016年3月—2019年3月行平板运动试验的阳性患者经冠脉造影结果为阳性,且资料完整者280例患者为研究对象,筛选出影响冠心病的独立危险因素。结果 性别、体质量指数(BMI)、高甘油三酯、平板恢复1、2 min心率是影响冠心病的独立危险因素。结论 对于男性、BMI>24、高甘油三酯、平板恢复1、2 min心率异常的患者,当其平板运动试验为阳性时,应建议其进一步行冠脉造影检查。
Objective To analyze the correlation between coronary angiography and the risk factors of coronary heart disease in patients with positive treadmill exercise test, so as to give early warning of coronary heart disease. Methods A total of 280 patients who underwent treadmill exercise tests from March 2016 to March 2019 in the Second Affiliated Hospital of Medical College of Zhejiang University were selected as the study subjects with positive coronary angiography results and complete data to screen out independent risk factors for coronary heart disease. Results Gender, body mass index, high triglycerides, high cholesterol, heart rate after 1 or 2 minutes of tablet recovery were the risk factors for positive coronary angiography. Conclusion For men, patients with BMI>24, high triglycerides, and abnormal heart rate after 1 or 2 minutes of tablet recovery, when the treadmill exercise test is positive, further coronary angiography should be recommended.
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