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2023年7月 第38卷 第7期11
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三重多原发恶性肿瘤病例分析

Analysis of triple multiple primary malignant neoplasms

来源期刊: 广州医药 | 34-38 发布时间:2023-02-07 收稿时间:2025/11/13 18:40:09 阅读量:19
作者:
关键词:
多原发恶性肿瘤乳腺癌甲状腺癌肺癌手术治疗
multiple primary malignant neoplasmsbreast cancerthyroid cancerlung cancersurgical treatment
DOI:
10.3969/j.issn.1000-8535.2023.01.006
收稿时间:
2022-03-04 
修订日期:
 
接收日期:
 
引用总数:
1  
目的 探讨多原发恶性肿瘤(MPMN)的临床特点,提高该类型肿瘤的认识,为临床诊断及治疗提供一定的经验。方法 分析2021年12月广州市第一人民医院呼吸与危重症学科二区收治的1例乳腺、甲状腺及肺三重多原发恶性肿瘤的临床特点及诊治经过,并结合相关文献进行回顾分析。结果 该例首患乳腺导管内癌并予手术切除,9年后再同时患肺癌及甲状腺癌,最终确诊为三重多原发恶性肿瘤。结论 通过对多原发恶性肿瘤的临床特点的分析研究,可一定程度提高临床医生对MPMN的认知以及早期临床鉴别的能力,亦为肿瘤患者早期诊断、早期治疗提供更好的时机,改善患者生活质量。
Objective To explore the clinical characteristics of multiple primary malignant neoplasms (MPMN), to improve the understanding of this type of tumors, and to provide some experience for clinical diagnosis and treatment. Methods The clinical characteristics, diagnosis and treatment of a case with triple MPMN of breast, thyroid and lung treated in the Respiratory and Critical Care Department (Area 2) of Guangzhou First People's Hospital in December 2021 were analyzed retrospectively. Results The breast intraductal carcinoma was the first tumor of that case and had been resected, and 9 years later, lung cancer and thyroid cancer occured at the same time, which were diagnosed as triple MPMN. Conclusions The analysis and study of the clinical characteristics of MPMN can improve the clinicians' cognition and the ability of early clinical differentiation, and provide a better opportunity for early diagnosis and early treatment of tumor patients, and improve their quality of life.
1、 刘苗苗,南岩东,陈艳丽,等.血清肿瘤标志物和自身抗体与肺癌患者临床病理特征的相关性研究[J]. 中华肺部疾病杂志,2018,11(2):176-181. 刘苗苗,南岩东,陈艳丽,等.血清肿瘤标志物和自身抗体与肺癌患者临床病理特征的相关性研究[J]. 中华肺部疾病杂志,2018,11(2):176-181.
2、 SUD A, THOMSEN H, SUNDQUIST K, et al. Risk of second cancer in hodgkin lymphoma survivors and influence of family history[J]. Clin Oncol,2017, 35(14):1584-1590. SUD A, THOMSEN H, SUNDQUIST K, et al. Risk of second cancer in hodgkin lymphoma survivors and influence of family history[J]. Clin Oncol,2017, 35(14):1584-1590.
3、 DONG L, HU S Y, ZHANG Q, et al. Dynamic changes of human papillomavirus genotype distribution in Shanxi cervical cancer screening cohort in 10 years[J]. Chin J Epidemiol,2017, 38(1):20-25. DONG L, HU S Y, ZHANG Q, et al. Dynamic changes of human papillomavirus genotype distribution in Shanxi cervical cancer screening cohort in 10 years[J]. Chin J Epidemiol,2017, 38(1):20-25.
4、 MAYADEV J, LIM J, DURBIN B, et al. Smoking decreases survival in locally advanced cervical cancer treated with radiation[J]. Am J Clin Oncol,2018,41(3):295-301. MAYADEV J, LIM J, DURBIN B, et al. Smoking decreases survival in locally advanced cervical cancer treated with radiation[J]. Am J Clin Oncol,2018,41(3):295-301.
5、 BERNSTEIN J L, WECARE Study Collaborative Group, CONCANNON P. ATM, radiation, and the risk of second primary breast cancer[J]. Int J Radiat Biol,2017,93(10):1121-1127. BERNSTEIN J L, WECARE Study Collaborative Group, CONCANNON P. ATM, radiation, and the risk of second primary breast cancer[J]. Int J Radiat Biol,2017,93(10):1121-1127.
6、 PAPPAS K, XU J, ZAIRIS S, et al. p53 maintains vaseline expression of multiple tumor suppressor genes[J]. Mol Cancer Res,2017,15(8):1051-1062. PAPPAS K, XU J, ZAIRIS S, et al. p53 maintains vaseline expression of multiple tumor suppressor genes[J]. Mol Cancer Res,2017,15(8):1051-1062.
7、 CHATURVEDI A K, ENGELS E A, GILBERT E S, et al. Second cancers among 104 760 survivors of cervical cancer: Evaluation of long-term risk[J]. J Natl Cancer Inst,2017,99(21):1634-1643. CHATURVEDI A K, ENGELS E A, GILBERT E S, et al. Second cancers among 104 760 survivors of cervical cancer: Evaluation of long-term risk[J]. J Natl Cancer Inst,2017,99(21):1634-1643.
8、 魏晓玲, 洪英极, 王林硕, 等. 潮汕地区原发性双侧乳腺癌癌灶间相关性分析[J]. 汕头大学医学院学报,2018,31(4):234-238. 魏晓玲, 洪英极, 王林硕, 等. 潮汕地区原发性双侧乳腺癌癌灶间相关性分析[J]. 汕头大学医学院学报,2018,31(4):234-238.
9、 宋诗平, 赵越, 王春玉, 等. 雌激素受体在甲状腺癌中作用的研究进展[J]. 第三军医大学学报,2017,29(5),489-494. 宋诗平, 赵越, 王春玉, 等. 雌激素受体在甲状腺癌中作用的研究进展[J]. 第三军医大学学报,2017,29(5),489-494.
10、 罗伟平, 何雩霏, 钟礼信, 等. 2008—2019年广州某综合医院肿瘤病例分析[J]. 广州医药, 2020, 51(4): 114-118. 罗伟平, 何雩霏, 钟礼信, 等. 2008—2019年广州某综合医院肿瘤病例分析[J]. 广州医药, 2020, 51(4): 114-118.
11、 魏星, 刘向阳.同时性多原发肺腺癌31例临床分析与治疗体会[J]. 中国医刊,2017,52(5):86-90. 魏星, 刘向阳.同时性多原发肺腺癌31例临床分析与治疗体会[J]. 中国医刊,2017,52(5):86-90.
12、 DUANMU Y Y, WANG R P. Professor Wang experience in the treatment of multiple primary cancer[J]. Guid J Tradit Chin Med Pharmacol,2018,24(9):53-54. DUANMU Y Y, WANG R P. Professor Wang experience in the treatment of multiple primary cancer[J]. Guid J Tradit Chin Med Pharmacol,2018,24(9):53-54.
13、 PAREKH J D, KUKRETY S, THANDRA A, et al. Multiple primary malignant neoplasms in an elderly patient[J]. Cureus,2018,10(3):2384. PAREKH J D, KUKRETY S, THANDRA A, et al. Multiple primary malignant neoplasms in an elderly patient[J]. Cureus,2018,10(3):2384.
14、 NEMES A, TODOR N, NAGY V. Clinicopathological characteristics of patients with multiple primary neoplasms-a retrospective analysis[J]. J BUON,2018,23(6):1846-1854. NEMES A, TODOR N, NAGY V. Clinicopathological characteristics of patients with multiple primary neoplasms-a retrospective analysis[J]. J BUON,2018,23(6):1846-1854.
15、 AL-HUSSEINI M J, MOHAMED H H, SAAD A M, et al. Risk and survival of chronic myeloid leukemia after breast cancer: A population-based study[J]. Curr Probl Cancer,2019,43(3):213-221. AL-HUSSEINI M J, MOHAMED H H, SAAD A M, et al. Risk and survival of chronic myeloid leukemia after breast cancer: A population-based study[J]. Curr Probl Cancer,2019,43(3):213-221.
16、 ZHAI C Y, CAI Y L, LOU F, et al. Multiple primary malignant tumors-A clinical analysis of 15,321 patients with malignancies at a single center in China[J]. J Cancer,2018,9(16):2795-2801. ZHAI C Y, CAI Y L, LOU F, et al. Multiple primary malignant tumors-A clinical analysis of 15,321 patients with malignancies at a single center in China[J]. J Cancer,2018,9(16):2795-2801.
17、 SIMEONOVSKI V, BRESHKOVSKA H, DUMA S, et al. Hydroxyurea associated cutaneous lesions: A case report[J]. Open Access Maced J Med Sci,2018,6(8):1458-1461. SIMEONOVSKI V, BRESHKOVSKA H, DUMA S, et al. Hydroxyurea associated cutaneous lesions: A case report[J]. Open Access Maced J Med Sci,2018,6(8):1458-1461.
18、 WANG H, HOU J, ZHANG G, et al. Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in patients with lung cancer[J]. Cancer Gene Ther,2019,26(11-12),419-426. WANG H, HOU J, ZHANG G, et al. Clinical characteristics and prognostic analysis of multiple primary malignant neoplasms in patients with lung cancer[J]. Cancer Gene Ther,2019,26(11-12),419-426.
19、 SINGH J, THOTA N, SINGH S, et al. Screening of over 1000 Indian patients with breast and/or ovarian cancer with a multi-gene panel:prevalence of BRCA1/2 and non-BRCA mutations[J]. Breast Cancer Res Treat,2018,170(1):189-196. SINGH J, THOTA N, SINGH S, et al. Screening of over 1000 Indian patients with breast and/or ovarian cancer with a multi-gene panel:prevalence of BRCA1/2 and non-BRCA mutations[J]. Breast Cancer Res Treat,2018,170(1):189-196.
20、 YAMAUCHI H, TAKEI J. Management of hereditary breast and ovarian cancer[J]. Int J Clin Oncol,2018,23(1):45-51. YAMAUCHI H, TAKEI J. Management of hereditary breast and ovarian cancer[J]. Int J Clin Oncol,2018,23(1):45-51.
1、张秀美,徐伟伟.胃间质瘤并发肝内胆管细胞癌、胰腺导管内黏液性乳头状瘤的多原发肿瘤1例[J].国际医药卫生导报,2023,29(14):2013-2015. 张秀美,徐伟伟.胃间质瘤并发肝内胆管细胞癌、胰腺导管内黏液性乳头状瘤的多原发肿瘤1例[J].国际医药卫生导报,2023,29(14):2013-2015.
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