您的位置: 首页 > 2018年9月 第49卷 第5期 > 文字全文
2023年7月 第38卷 第7期11
目录

直接面向消费者的基因检测相关需求分析

Demand analysis of the directly to consumers genetic testing

来源期刊: 广州医药 | 98-103 发布时间:2021-11-29 收稿时间:2025/11/13 17:19:18 阅读量:25
作者:
关键词:
基因检测直接面向消费者检测目的知晓途径
Genetic testingDirect-to-consumersDetection purposeKnowledge pathway
DOI:
10.3969/j.issn.1000-8535.2018.05.024
收稿时间:
2018-07-05 
修订日期:
 
接收日期:
 
引用总数:
0  
目的 通过对未进行过商业基因检测(NCGT)社区居民和直接面向消费者的基因测试(DCGT)消费群体的调查,分析市场基因测试产品的消费构成和消费者社会特征与基因检测消费的相关因素。方法 采用分层随机抽样方法对广州市居民和直接面向消费者的基因检测非患者居民进行面访式调查,采用Logistics回归分析商业基因测试的相关社会学因素。结果 NCGT社区居民中其家庭成员进行过胎儿产前筛查基因检测的比例(26.3%)较高、DCGT人群因常规健康体检包含基因检测项目而进行基因测试的比例(44.8%)最高,儿童天赋基因的测试比例(23.3%)也相对较高,两个群体均认为基因检测的目的主要是预防疾病,信任的检测机构为医院。DCGT行为相关的社会学特征有婚姻(已婚vs未婚:OR=5.591,P<0.001)、学历(专科以上vs专科及以下:OR=0.071,P<0.001)、年龄(30~49岁组vs其他组:OR=0.223,P<0.001)、工作(全职vs其他:OR=4.660,P<0.001)、公费医疗(OR=1.183,P=0.021)和商业保险(OR=2.121,P=0.004)。结论 公众将基因测试看成是预防疾病和控制遗传性疾病的公共卫生手段,需要在医院将基因检测和个性化治疗对应起来。
Objective By investigating consumer groups that have no-commercial genetic testing (NCGT) community residents and direct-to-consumers genetic testing (DCGT), to analysze the consumer composition of market genetic testing products and the factors related to consumer social characteristics. Methods A stratified random sampling method was used to conduct a face-to-face survey of residents and non-patients of genetic testing in Guangzhou residents. The logistic regression analysis was used to analyze the sociological factors of commercial genetic testing. Results The proportion of children in the NCGT community who had prenatal screening for prenatal screening (26.3%) was higher, and the proportion of DCGT populations that were genetically tested for routine health checkups containing genetic testing (44.8%) was the highest. The proportion of test genes (23.3%) is also relatively high. Both groups believe that the purpose of genetic testing is mainly to prevent diseases, and the testing institutions for their trust are hospitals. The sociological characteristics associated with DCGT behavior are marriage (married vs unmarried: OR=5.591, P<0.001), education (specialist vs. specialist and below: OR=0.071, P<0.001), age (30~49 years vs others, OR=0.223, P<0.001), work (full-time vs other: OR=4.660, P<0.001), public medical care (OR=1.183, P=0.021) and commercial insurance (OR=2.121, P=0.004). Conclusion The public regards genetic testing as a public health tool for preventing diseases and controlling hereditary diseases, and it is necessary to correlate genetic testing with personalized treatment in hospitals.
1、 QUILLIN J M. Lifestyle Risk factors among people who have had cancer genetic testing[J]. J Genet Counsel, 2015, 25(5):1-8. QUILLIN J M. Lifestyle Risk factors among people who have had cancer genetic testing[J]. J Genet Counsel, 2015, 25(5):1-8.
2、 LANE M, NGUENG F I, JOLY Y. Genetics and personal insurance: the perspectives of canadian cancer genetic counselors[J]. J Genet Counse, 2015, 24(6):1022-1036. LANE M, NGUENG F I, JOLY Y. Genetics and personal insurance: the perspectives of canadian cancer genetic counselors[J]. J Genet Counse, 2015, 24(6):1022-1036.
3、 LANDRY L, NIELSEN D E, CARERE D A, et al. Racial minority group interest in direct-to-consumer genetic testing: findings from the PGen study[J]. J Community Genet, 2017, 8(4):293-301. LANDRY L, NIELSEN D E, CARERE D A, et al. Racial minority group interest in direct-to-consumer genetic testing: findings from the PGen study[J]. J Community Genet, 2017, 8(4):293-301.
4、 CARERE D A, KRAFT P, KAPHINGST K A, et al. Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing[J]. Genet Med, 2016, 18(1):65-72. CARERE D A, KRAFT P, KAPHINGST K A, et al. Consumers report lower confidence in their genetics knowledge following direct-to-consumer personal genomic testing[J]. Genet Med, 2016, 18(1):65-72.
5、 SCHWARTZ M K, LUIKART G, WAPLES R S. Genetic monitoring as a promising tool for conservation and management[J]. Trends Ecol Evo, 2007, 22(1):25-33. SCHWARTZ M K, LUIKART G, WAPLES R S. Genetic monitoring as a promising tool for conservation and management[J]. Trends Ecol Evo, 2007, 22(1):25-33.
6、 BIRMINGHAM W C, AGARWAL N, KOHLMANN W, et al. Patient and provider attitudes toward genomic testing for prostate cancer susceptibility: a mixed method study[J]. Bmc Health Serv Res, 2013, 13(1):279-287. BIRMINGHAM W C, AGARWAL N, KOHLMANN W, et al. Patient and provider attitudes toward genomic testing for prostate cancer susceptibility: a mixed method study[J]. Bmc Health Serv Res, 2013, 13(1):279-287.
7、 THIEL D B, PLATT T, PLATT J, et al. Community perspectives on public health biobanking: an analysis of community meetings on the Michigan BioTrust for Health[J]. J Community Genet, 2014, 5(2):125-138. THIEL D B, PLATT T, PLATT J, et al. Community perspectives on public health biobanking: an analysis of community meetings on the Michigan BioTrust for Health[J]. J Community Genet, 2014, 5(2):125-138.
8、 ROBERTS J S, OSTERGREN J. Direct-to-consumer genetic testing and personal genomics services: a review of recent empirical studies[J]. Curr Genet Med Rep, 2013, 1(3):182-200. ROBERTS J S, OSTERGREN J. Direct-to-consumer genetic testing and personal genomics services: a review of recent empirical studies[J]. Curr Genet Med Rep, 2013, 1(3):182-200.
9、 LIANG M I, WONG D H, WALSH C S, et al. Cancer genetic counseling and testing: perspectives of epithelial ovarian cancer patients and gynecologic oncology healthcare providers[J]. J Genet Couns, 2017,27(10):177-186. LIANG M I, WONG D H, WALSH C S, et al. Cancer genetic counseling and testing: perspectives of epithelial ovarian cancer patients and gynecologic oncology healthcare providers[J]. J Genet Couns, 2017,27(10):177-186.
10、 成小林, 李正东, 孙晓寅,等. 乳腺癌患者血亲亲属对遗传咨询和基因检测意愿的调查[J]. 复旦学报(医学版), 2017, 44(3):312-318. 成小林, 李正东, 孙晓寅,等. 乳腺癌患者血亲亲属对遗传咨询和基因检测意愿的调查[J]. 复旦学报(医学版), 2017, 44(3):312-318.
11、 EMMET M, STEIN Q, THORPE E, et al. Experiences of genetic counselors practicing in rural areas[J]. J Genet Couns, 2018, 27(1):140-154. EMMET M, STEIN Q, THORPE E, et al. Experiences of genetic counselors practicing in rural areas[J]. J Genet Couns, 2018, 27(1):140-154.
12、 薛迪, 白洁, 王剑萍,等. 临床医生在基因检测咨询中伦理两难问题态度与选择——基于情景案例分析[J]. 中国医院管理, 2015, 35(4):74-77. 薛迪, 白洁, 王剑萍,等. 临床医生在基因检测咨询中伦理两难问题态度与选择——基于情景案例分析[J]. 中国医院管理, 2015, 35(4):74-77.
13、 贺文. 盯上你的DNA[J]. IT经理世界, 2016(16):38-39. 贺文. 盯上你的DNA[J]. IT经理世界, 2016(16):38-39.
14、 MODELL B, DARR A. Science and society: genetic counselling and customary consanguineous marriage.[J]. Nat Rev Genet, 2002, 3(3):225-229. MODELL B, DARR A. Science and society: genetic counselling and customary consanguineous marriage.[J]. Nat Rev Genet, 2002, 3(3):225-229.
15、 THOMPSON C, HAMILTON S P, HIPPMAN C. Psychiatrist attitudes towards pharmacogenetic testing, direct-to-consumer genetic testing, and integrating genetic counseling into psychiatric patient care[J]. Psychiatry Res, 2015, 226(1):68-72. THOMPSON C, HAMILTON S P, HIPPMAN C. Psychiatrist attitudes towards pharmacogenetic testing, direct-to-consumer genetic testing, and integrating genetic counseling into psychiatric patient care[J]. Psychiatry Res, 2015, 226(1):68-72.
上一篇
下一篇
出版者信息








《广州医药》公众号
目录