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《广州医药》编辑部

广州医药杂志服务号
论著

FRAX®评估广州社区中老年人群骨折风险的回顾性研究

A retrospective study of FRAX in predicting the fracture risk of senile people in Guangzhou community

:-
 
目的 应用FRAX®工具评估广州社区中老年人发生骨质疏松性骨折的风险。方法 回顾性研究1 140例广州社区中老年人的临床资料,应用FRAX®工具计算未来10年发生主要骨质疏松性骨折及髋部骨折的风险,分析不同危险因素与骨折风险的关系。结果 广州社区中老年人群10年内发生主要骨质疏松性骨折概率为(4.2±3.6)%,髋部骨折概率为(1.3±2.4)%。主要骨质疏松性骨折风险及髋部骨折风险、OSTA值均随着年龄增长而增加。多因素回归分析结果显示: 年龄、性别、既往骨折、继发性骨质疏松、股骨颈T值、跌倒对主要部位骨折及髋部骨折风险具有独立性预测意义。结论 FRAX®工具可用于评估广州社区中老年人骨质疏松性骨折风险,建议在社区中老年人健康体检时应用FRAX®工具进行骨折风险评估。
Objective To predict the osteoporotic fracture risk in senile people in Guangzhou communities by FRAX,the fracture risk assessment tool published by WHO. Methods Clinical data of 1140 cases were collected for the retrospective analysis. The FRAX tool was uesed to calculate the 10-year probability of a major osteoporotic and hip fracture.The relationship between different risk factors and the fracture risk predicted by FRAX was analyzed. Results The 10-year probability of major osteoporotic fractures was (4.2±3.6)%, and the 10-year probability of hip fractures was (1.3±2.4)%.The 10-year probability of the major osteoporotic and hip fracture increased with age.Multivariate regression analysis showed that age,gender,previous fracture,secondary osteoporosis,T-score of femoral neck BMD and fall were independent predictors of the 10-year probability of major osteoporotic fracture and hip fracture. Conclusion The FRAX tool may be effectively applied to assess the fracture risk of senile population in Guangzhou communities.We recommedated that FRAX-tool should be included in routine health check-up.
论著

胸腔镜探查同期行肋骨骨折内固定治疗胸外伤的价值

The treatment of severe thoracic trauma by thoracoscopic surgery and internal fixation of rib fracture

:48-50
 
目的 探讨重症胸外伤患者在行胸腔镜手术探查同期行肋骨骨折内固定术的有效性和临床意义。方法 选取我院2008年—2017年收治的68例具有胸腔镜手术探查指征的重症胸外伤患者,其中36例同期行肋骨骨折内固定术,32例单纯行胸腔镜探查术。比较2组患者的VAS评分、镇痛药物用量、卧床时间、住院天数等。结果 2组患者术后VAS评分、镇痛药物用量、卧床时间、住院天数等有统计学差异。结论 胸腔镜手术探查同期行肋骨骨折内固术治疗重症胸外伤可降低术后并发症的发生,加速患者的康复,值得推广。
Objective To investigate the clinical significance and effectiveness of thoracic endoscopic surgery for patients with severe thoracic trauma. Methods 68 cases of severe thoracic trauma with thoracoscopic operation, of which 36 cases underwent internal fixation of rib fracture and 32 cases were performed by thoracoscope. The VAS score, analgesic dosage, bed time and hospitalization days were compared between the two groups. Results There were significant differences in VAS score, analgesic dosage, bed time and hospitalization days after operation in the two groups. Conclusion The treatment of severe thoracic trauma by thoracoscopic surgery and internal fixation of rib fracture may reduce postoperative complications and accelerate the recovery of patients, which is worth popularizing.
论著

应用康复护理路径早期功能训练对桡骨远端骨折内固定术后患者腕关节功能康复的影响

Effects of early rehabilitation training on the recovery of wrist function after distal radius fracture fixation

:78-81
 
目的 探讨康复护理路径早期功能训练对桡骨远端骨折LCP(锁定加压接骨板locking compression plate, LCP)内固定术后患者腕关节功能康复的影响。方法 对2014年5月—2016年6月住院80例桡骨远端骨折LCP 内固定术后患者分为对照组和观察组,每组各40例,对照组按桡骨远端LCP内固定术后护理措施进行护理,观察组患者在此护理基础上,制定术后功能康复护理路径,按功能康复护理路径对术后患者实施早期功能康复训练,随访评价两组患者患肢的组织肿胀、疼痛、骨折复位和腕关节功能康复效果。结果 疼痛评分:对照组在术后第3天~14天疼痛评分均高于观察组(P<0.005);肿胀程度评分:对照组在术后第3天~7天肿胀程度评分均高于观察组,消肿速度比观察组慢(P<0.001);腕关节的屈伸活动范围、握力和捏力比较观察组优于对照组(P<0.001);腕关节复位优良率观察组95%高于对照组87.5%(P<0.001)。结论 应用康复护理路径对桡骨远端骨折的LCP内固定术后患者进行早期腕关节功能康复训练,能减轻患者疼痛和局部软组织肿胀,减少并发症,提高术后患者康复质量。
Objective To investigate the early functional training of rehabilitation nursing path to the effects of distal radius fracture LCP (locking compression plate LCP) in patients after internal fixation of wrist joint function rehabilitation. Methods From May 2014 to June 2016, 80 patients with distal radius fractures were divided into control group and observation group(n=LCP), each with 40 cases. The control group was treated with nursing care of patients with distal radius LCP internal fixation. On the basis of nursing, the patients in the observation group were given rehabilitation nursing pathway, and the patients were followed up according to the rehabilitation path including evaluation of two groups of patients with fracture limb swelling, pain, fracture reduction and wrist joint function rehabilitation. Results Pain score: in the third days to fourteenth days pain score of the control group was higher than the observation group (P<0.005); Swelling degree score: swelling scores of the control group for the third days to seventh days after were higher than those in the observation group, the swelling reduced slowly (P<0.001); The wrist flexion range, grip and pinch strength compared to the observation group was better than the control group (P<0.001); The good rate of wrist joint reduction in the observation group (95%) was higher than that in the control group[(87.5%) (P<0.001)]. Conclusion The application of rehabilitation nursing path for patients with distal radius fracture after LCP internal fixation for early rehabilitation of wrist function may reduce the pain and local soft tissue swelling, reduce complications and improve the quality of postoperative rehabilitation.
论著

高黏度骨水泥在治疗骨质疏松性椎体压缩性骨折中的临床应用

The clinical analysis of high viscosity bone cement for treatment of osteoporotic vertebral compression fractures

:49-51
 
目的 探讨高黏度骨水泥在治疗骨质疏松性椎体压缩性骨折中的临床疗效分析。方法 随机选取本院2012年1月—2016年1月收治的80例骨质疏松椎体压缩性骨折患者。将患者随机分为对照组和观察组,每组各40例,均采用骨水泥联合经皮椎体后凸成形术治疗,对照组采用低黏度骨水泥,观察组采用高黏度骨水泥。采用视觉模拟量表(VAS)评分比较手术前后患者疼痛情况,Oswestry指数(Oswestry disability index,ODI)评分评估患者腰背部功能。观察并比较两组患者VAS、ODI评分,骨水泥渗漏及相关并发症情况。结果 所有患者均顺利完成手术,术后随访1年以上,期间未发生严重并发症。所有患者VAS评分,ODI评分均明显高于术前。两组均出现骨水泥渗漏及其他并发症,低黏度骨水泥组骨水泥渗漏率为66.7%,明显高于高黏度骨水泥组的33.3%,P<0.05,但均无明显神经功能损伤。结论 高黏度骨水泥在骨质疏松椎体压缩性骨折中的应用能显著改善患者临床疗效,明显降低骨水泥渗漏及并发症的发生率。
Objective To investigate the clinical effect of high viscosity bone cement for treatment of osteoporotic vertebral compression fractures. Methods From Jan. 2012 to Jan. 2016, 80 patients with osteoporosis vertebral fractures were enrolled into this study. They were randomly divided into control group and observation group, with 40 cases in each group. They were all adopted PKP methods for treating, while the observation group got the high viscosity bone cement and the control group got the low one. Clinical outcomes were assessed in terms of back pain visual analogue scale (VAS), Oswestry disability index (ODI) after surgery.The outcomes of back pain VAS score, ODI, venous leakage rate, discoidal leak rate, rate of around vertebral body, rate of contiguous vertebral fracture were compared between two groups. Results All patients were successfully completed surgery. We took postoperative follow-up more than one year, there were severe complications occurred. VAS score, ODI score were significantly higher than that of before operation. Two groups had both bone cement leakage and other complications. Low viscosity bone cement group of bone cement leakage rate was 66.7%, significantly higher than the 33.3% of the high viscosity of bone cement group, P<0.05, but no obvious neurologic injury. Conclusion The high-viscosity bone cement for osteoporotic vertebral fractures provides better clinical outcomes. It may reduce bone cement leak rate and complications.
临床诊疗

多层螺旋三维CT重建引导下的改良Evans分型对老年脆骨性粗隆间骨折微创治疗的临床指导

Improved Evans parting under multi-slice spiral CT three-dimensional reconstruction in mini-invasive surgical treatment of elderly cartilage intertrochanteric fractures

:116-119
 
目的 利用新的分型方法指导现有的微创技术下内固定的选择,提示预后,帮助制定术后康复计划。方法 将200例患者随机分成两组,一组为旧Evans分型组,另一组为改良Evans分型组,通过多层螺旋三维CT重建引导下改良Evans分型,对三个重点区域(股骨内距、头颈部及粗隆外侧入针点部位)的CT成像,利用多平面重组(MPR)、表面遮盖显示(SSD)及容积再现(VR)等多种后处理,分析骨折线走形、局部的微骨折、骨小梁分布、骨皮质厚度的骨折部内环境变化。简化整合到Evans分型中。来实现完善影像分型,有效地指导微创手术。对比两组患者的疗效。结果 新Evans分型组98例患者愈合良好,时间为9~17周,中位数为11.2周。其中伤口感染3例,髋关节内翻畸形3例,骨骨头坏死3例,按照髋关节治疗标准评分,优53例,良31例,可9例,差7例。优良率(包括优和良)为84%。旧Evans分型组80例患者愈合良好,时间为9~18周,中位数为11.8周。其中伤口感染10例,髋关节内翻畸形5例,股骨头坏死8例,按照髋关节治疗标准评分,优48例,良26例,可10例,差16例。优良率(包括优和良)为74%。两组对比,新Evans分型组优良率明显高于旧Evans分型组,差异有统计学意义。P<0.05。结论 多层螺旋三维CT重建引导下的改良Evans分型对老年脆骨性粗隆间骨折的微创治疗有重要的临床指导意义。
论著

胸腰椎骨折内固定术后患者早期康复护理与常规性护理的对照研究

Comparative study of early rehabilitation nursing and routine nursing care for patients with thoracolumbar bursting fracture after internal fixation

:96-99
 
目的 探讨早期康复护理干预对胸腰椎骨折内固定术后患者的临床护理效果。方法 2014年6月—2016年12月,将94例胸腰椎骨折内固定术后患者按数字随机法,分为实验组51例和对照组43例,分别实进行早期康复护理和常规性护理。比较两组患者胸腰背部功能状况、胸腰背部疼痛情况、术后抑郁水平,以及护理满意度等相关指标,以评价早期康复护理的效果。结果 94例患者均获得3个月随访。与对照组比较,实验组患者平均住院天数减少4.1 d,差异有统计学意义(P<0.05);平均住院费用也有所下降;实验组和对照组总并发症发生率分别为7.84%和20.9%,两组间比较差异有统计学意义;实验组的护理工作满意度高达90.20%,高于对照组的67.44%,差异具有统计学意义(P<0.05)。术后3个月随访时,Oswestry功能障碍评分实验组为(14.74±3.25),低于对照组的(20.04±5.32)(P<0.05); SDS评分实验组的为42.35±3.68,低于对照组的(47.28±3.49)(P<0.05);胸腰背痛VAS评分实验组的为(1.07±0.67),低于对照组的(2.62±1.86)(P<0.05)。结论 早期康复护理干预是促进胸腰椎骨折内固定术后患者快速康复的有效方法,提高患者对护理工作的满意度,值得推广应用。
Objective To evaluate and compare the outcomes of early rehabilitation nursing and routine nursing care for patients with thoracolumbar bursting fracture after internal fixation. Methods From June 2014 to December 2016, this study enrolled ninety-four subjects who were randomly divided into observe group with fifty-one cases and control group with forty-three cases according to the digital random method. Patients in the control group were treated with routine nursing care, and early rehabilitation nursing care were used in the observe group. The physical function of thoracolumbar spine, psychological condition, pain of thoracolumbar spine, nursing satisfaction and soon. were compared between the two groups. Results The average days of hospital stay in the observation group was 4.10 days, it was less than that of control group, and the difference was statistically significant(P<0.05). Average hospital costs were also declined. The total complication rate were 7.84% in observe group and 20.9% in control group, there was significant difference between the two groups (P<0.05). The nursing satisfaction was 90.20% in observe group, which was higher than 67.44% in that in control group (P<0.05). When follow-up three months after operation, the ODI score in experiment group was(14.74±3.25), which was lower than that (20.04±5.32)in control group (P<0.05). The SDS score in experiment group was (42.35±3.68), which was lower than that (47.28±3.49)in control group(P<0.05). And the VAS score in experiment group was (1.07±0.67), which was lower than that(2.62 ±1.86)in control group (P<0.05). Conclusion Early rehabilitation nursing care is effective to the rapid functional recovery for patients with thoracolumbar bursting fracture after internal fixation, and improves the nursing satisfaction.
论著

爪形肋骨接骨板治疗多发肋骨骨折的临床研究

Clinical studies of rib jaw-shaped bone plate for the treatment of multiple rib fractures

:70-72
 
目的 探讨爪形肋骨接骨板内固定治疗多发肋骨骨折的临床价值及意义。方法 收集2015年6月—2016年12月收治多发肋骨骨折40例,其中手术内固定20例,保守治疗组20例,比较分析两组临床治疗情况。结果 所有患者均痊愈出院,手术内固定组比保守治疗组疼痛明显减轻,胸管留置时间、下床自主活动时间及住院时间短,并发症发生率低,胸廓畸形矫正更满意,差异有统计学意义(P<0.05)。结论 爪形肋骨接骨板内固定术治疗多发肋骨骨折固定效果满意,手术操作简单、创伤小,术后并发症少,恢复快,值得临床推广应用。
Objective To investigate the clinical value and significance of rib jaw-shaped bone plate in the treatment of multiple rib fractures. Methods 40 patients with multi-rib fractures were selected from June 2015 to November 2016. 20 cases were performed of rib jaw-shaped bone plate in the surgical treatment,20 cases of conservative treatment. The clinical treatment conditions of two groups were compared. Results Patients in both groups were all cured. Pain perception, hospital stay time, retain time of thoracic duct and independent ambulation time in surgery group were obviously reduced comparing with conservative treatment group as well as the surgical complications. There was a significant differences(P<0.05). Conclusion Rib jaw-shaped bone plate for the treatment of multiple rib fractures has satisfactory results.Its advantages are as follows:simple and quick operative technique,minimal invasive surgery,less complications, fast recovery. It is worthy of clinical application.
论著

全髋关节置换术对于股骨颈骨折的老年患者适用性研究

Study on the applicability of total hip arthroplasty in elderly patients with femoral neck fracture

:67-69
 
目的 研究全髋关节置换术对于股骨颈骨折老年患者的适用性。方法 回顾性分析本院2012年1月—2014年1月间收治的89例股骨颈骨折老年患者,根据不同治疗术式将患者分为两组,将其中采取人工全髋关节置换术治疗的56例患者纳入全髋组,以将其中采取半髋关节置换术治疗的33例患者纳入半髋组,对比两组患者的手术情况,随访一年评估疗效并统计功能恢复时间以及并发症发生情况。结果 半髋组各项手术情况观察指标均优于全髋组,P<0.05;治疗后随访一年,全髋组总有效为96.43%,半髋组总有效率为93.94%,全髋组疗效优于对照组,P<0.05;全髋组并发症发生率为3.57%,半髋组并发症发生率为18.18%,全髋组并发症发生率优于半髋组,P<0.01。结论 全髋关节置换术治疗股骨颈骨折老年患者适用性高于半髋关节置换术,可考虑作为老年患者的首选术式加以推广。
Objective To study the applicability of total hip arthroplasty in elderly patients with femoral neck fracture. Methods A retrospective analysis of 89 cases of elderly patients with femoral neck fracture in our hospital was made from January 2012 to January 2014, according to different surgical methods. The patients were divided into two groups, among them 56 cases of total hip arthroplasty were in the total hip group, and 33 cases of hip replacement were in the semi hip arthroplasty group. To compare the surgery condition, one year of follow-up evaluation of occurrence curative effect was made and added up the function recovery time and complications in the two groups. Results The surgical observation indicators in the semi arthroplasty group were better than the total hip group, P<0.05; follow-up one year after the treatment, the total effective rate of the total hip group was 96.43%, that in the semi hip arthroplasty group was 93.94%, thus the curative effect of the total hip group was better than the control group, P<0.05; The incidence of complications of the total hip arthroplasty group was 3.57%, that in the semi hip arthroplasty group was 18.18%, thus the incidence of complications of the total hip group was better than the semi hip group, P<0.01. Conclusion The adaptability of the total hip arthroplasty in the treatment of elderly patients with femoral neck fractures is better than the semi hip replacement surgery, and it may be considered as the first choice for the elderly patients to promote.
临床诊疗

国内初次生物型人工髋关节置换后股骨假体周围骨折的Vancouver分型及其治疗分析

Vancouver parting of periprosthetic femur fracture after the first civil biological artificial hip arthroplasty and treatment

:61-68
 
通过文献检索,对2001—2016年我国学者在国内发表的有关人工髋关节置换后假体周围骨折的Vancouver分型及其治疗方法进行汇总、归纳和分析, 总结分析国内初次生物型人工髋关节术后假体周围骨折病例的Vancouver分型及其不同治疗方法的优良率,为临床决策中选择适合的手术方法提供一定的参考借鉴。共有 117 篇文献入选,统计结果显示入选病例数前三位的省份分别是河南220例占13.3%,上海173例占10.5%,江苏163例占9.9%;Vancouver分型中A型骨折201例占12.2%,B型骨折1226例占74.4%,C型骨折221例占13.4%。AG型骨折行记忆合金环抱器或钢丝环扎+植骨治疗,AL型骨折行翻修+锁定钢板+钢丝或翻修+锁定钢板+植骨治疗,疗效显著;B1、B2、B3型骨折分别采用加压钢板+植骨、翻修+钢板+钢丝+植骨、翻修+记忆合金环抱器+植骨治疗,术后平均优良率可达100%;C 型骨折治疗方法较多,如LISS钢板+植骨、锁定钢板+钢丝、股骨髁钢板+钢缆+植骨、动力髋钢板+钢丝,疗效均较满意。我国人工髋关节置换术地区间开展不平衡,应根据Vancouver 分型,综合考虑患者骨折类型、骨折位置、假体稳定性、骨量丢失情况等提出个体化的治疗方案,提高临床疗效。
论著

多层螺旋CT重建技术在儿童胸部复合型骨折诊断中的价值

The value of MSCT reconstruction in the diagnosis of children's chest complex fractures

:48-52
 
目的 回顾性分析常规放射检查中儿童胸部复合型骨折漏诊的原因,并且探讨多层螺旋CT后处理技术在儿童胸部复合型骨折中的诊断价值。方法 搜集本院2012年1月—2015年8月间因外伤行胸部照片和CT扫描的外伤患儿共123例,男81例,女42例,年龄9个月~15岁,平均年龄4.3岁。所有病例在完成胸部照片后1~3 d,进行胸部容积CT扫描,并对数据进行三维重建后处理,其结果与常规DR检查结果相比较。结果 在123例患儿中,常规胸部DR片显示明确胸部骨折39例61处,其中胸部单纯性骨折24例,胸部复合型骨折15例。可疑骨折48例;36例未见明确骨折但存在胸部合并症。CT检查显示明确的胸部骨折76例,142处,其中胸部单纯性骨折42例,胸部复合型骨折34例。与胸部DR平片相比,CT显示胸部新增骨折有18处在单纯性骨折病例中,63处在复合型骨折病例中。CT重建技术对复合型骨折的检出率高于DR平片,差异有统计学意义(P<0.05)。结论 胸部CT容积扫描并综合运用三维重建技术处理,可以提高胸部复合型骨折的检出率,相对于常规放射照片更能提供详细和直观的信息,包括骨折部位、类型、程度以及邻近结构的损伤,并对治疗方案的选择及预后的评估有重要指导价值。
Objective To investigate the reasons for missed diagnoses of children's chest complex fractures in chest radiographs and to discuss the value of multi-slice spiral CT (MSCT) reconstruction in the diagnosis of children's chest complex fractures. Methods 123 children underwent chest digital radiography(DR) and MSCT scans after traumas were collected in our hospital between January 2012 and August 2015. This population consisted of 81 male and 42 female patients, with a mean age of 4.3 years(range from 9 months to 15 years). All participants underwent chest MSCT scans in 1-3 days after completing chest DR, and then we used 3D reconstruction to process the data and compared the results with those processed by DR. Results By chest DR tests we identified 39 cases (61 places) out of 123 participants with 24 simple fractures, 15 complex fractures. And 48 chest fractures were suspected. We also identified 36 cases had chest complications without fracture. By MSCT scans 76 cases (142 places) were identified, among which 42 were simple and 34 were complex. Compared with chest DR, MSCT scans can identified 18 more places of simple fractures and 63 more places of complex fractures. It was statistically significant higher detection rate of MSCT scan than DR. Conclusion Chest MSCT scan combined 3D reconstruction technology can increase the detection rate of chest complex fracture. Compared with DR, it provides more detailed and visualized information, including fracture position, type, severity and adjacent structure damage. It has important guiding value on the selection of therapy and prognosis evaluation.
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