羌活胜湿汤对风湿外感头痛患者的疗效分析

doi:10.3969/j.issn.1000-8535.2022.04.015

摘要/Abstract

摘要： 目的研究羌活胜湿汤对风湿外感头痛患者的疗效。方法选择2018年1月—2020年12月我院收治的62例风湿外感头痛患者,随机分为2组。对照组服用5 mg的氟桂利嗪胶囊,每晚1次;观察组联用羌活胜湿汤。比较2组风湿外感头痛患者的有效率,治疗前后的睡眠质量评分和视觉模拟评分法(VAS)评分。结果观察组风湿外感头痛患者的有效率(96.77%)高于对照组(80.64%) (P<0.05);治疗前,2组风湿外感头痛患者的VAS评分无差异(P>0.05),治疗后,2组风湿外感头痛患者的VAS评分降低(P<0.05),且观察组风湿外感头痛患者的VAS评分更低(P<0.05);治疗前,2组风湿外感头痛患者的夜间苏醒、入睡时间、睡眠深度、早醒、白天情绪、梦境情况、气色和白天身体状况评分无差异(P>0.05),治疗后,2组风湿外感头痛患者的夜间苏醒、入睡时间、睡眠深度、早醒、白天情绪、梦境情况、气色和白天身体状况评分降低(P<0.05),且观察组风湿外感头痛患者的夜间苏醒、入睡时间、睡眠深度、早醒、白天情绪、梦境情况、气色和白天身体状况评分低于对照组(P<0.05)。结论羌活胜湿汤对风湿外感头痛患者有显著的疗效,与其能明显减轻疼痛程度和改善睡眠质量有关。

关键词: 羌活胜湿汤, 风湿外感头痛, 疗效, 机制

Abstract: Objective To investigate the effect of Qianghuo Shengshi decoction on patients with wind-damp headache. Methods A total of 62 cases of patients with wind-damp headache who were treated in our hospital from January 2018 to December 2020 were selected and divided into two groups randomly. The control group took 5 mg of flunarizine capsules once a night; the observation group took Qianghuo Shengshi decoction additionally. The effective rate, sleep quality score and visual analogue scale(VAS) score before and after treatment were compared between the two groups of patients. Results The effective rate of the observation group (96.77%) was significantly higher than that of the control group (80.64%, P<0.05). Before treatment, the VAS scores of the two groups of patients with exogenous wind-damp headache were not significantly different (P>0.05). After treatment, the VAS scores of the two groups were significantly reduced (P<0.05), and the score drop of the observation group was significant (P<0.05). Before treatment, there were no significant differences in night awakening, sleep time, sleep depth, early awakening, daytime mood, dream condition, complexion and daytime physical condition score between the two groups (P>0.05), after treatment, the scores of night awakening, sleep time, sleep depth, early awakening, daytime mood, dream condition, complexion and daytime physical condition in patients with wind-damp headache in both groups were significantly decreased (P<0.05), and the scores of night awakening, sleep time, sleep depth, early awakening, daytime mood, dream condition, complexion and daytime physical condition in patients with wind-damp headache in the observation group were significantly lower than those in the control group (P<0.05). Conclusions Qianghuo Shengshi decoction had a significant effect on patients with wind-damp headache, and its was related to its ability of significant pain reduction and sleep quality improvement.

Key words: Qianghuo Shengshi decoction, wind-damp headache, curative effect, mechanism

张爱婷, 赵素霞, 刘文娟, 岳丽丹, 贾秀梅. 羌活胜湿汤对风湿外感头痛患者的疗效分析[J]. 广州医药, 2022, 53(4): 65-68.

ZHANG Aiting, ZHAO Suxia, LIU Wenjuan, YUE Lidan, JIA Xiumei. Therapeutic effect analysis of Qianghuo Shengshi decoction on patients with wind-damp headache[J]. Guangzhou Medical Journal, 2022, 53(4): 65-68.

参考文献

[1] LIU Y, XU F, WHEATON A G, et al. The association between inflammatory bowel disease and migraine or severe headache among US adults: Findings from the National Health Interview Survey, 2015—2016[J]. Headache, 2021, 61(4):612-619.
[2] 任泳燕, 李慧, 王洋洋,等. 《中医内科常见病诊疗指南——头痛》指南更新与解读[J]. 中国循证医学杂志, 2020, 20(6):29-36.
[3] 胡珊珊, 董丽, 白雪,等. 杨思进教授治疗风湿夹瘀性偏头痛[J]. 世界最新医学信息文摘, 2019, 19(60):372,376.
[4] 周仲瑛. 中医内科学[M]. 7 版. 北京:中国中医药出版社,2003: 303-312.
[5] 张明园.精神科评定量表手册[M]. 2版. 长沙: 湖南科学计术出版社, 1998: 81.
[6] GAGO-VEIGA A B, GARCÍA-AZORÍN D, MAS-SALA N, et al. How and when to refer patients diagnosed with primary headache and craniofacial neuralgia in the Emergency department or Primary Care: Recommendations of the Spanish Society of Neurology's Headache Study Group[J]. Neurologia (Engl Ed), 2020, 35(3):176-184.
[7] 李红宇, 丁志毅, 王明明. 火针联合麻黄桂枝各半汤加减对外感风寒性头痛患者疼痛及生活质量的影响[J]. 世界中西医结合杂志, 2020, 15(1):137-140.
[8] 熊兴江. 基于CCU重症病例的《伤寒六书》柴葛解肌汤方证及其在医院内感染,急性上呼吸道感染等外感热病中的运用[J]. 中国中药杂志, 2019, 44(18):46-52.
[9] 孙宁宁, 张松江, 武鑫,等. 经方六经辨证治疗头痛的临床应用体会[J]. 中国中医药现代远程教育, 2019,17(1):60-61.
[10] 方中明, 黄鹏, 黄接福,等. 关节镜下半月板修复术后配合羌活胜湿汤加减口服治疗术后疼痛残留分析[J]. 药品评价, 2020, 17(2):59-60.
[11] 张会择, 余宗明, 傅勤为,等. 从《黄帝内经》痰瘀理论探讨葛根、川芎、石菖蒲药组的脉证规律及临床应用[J]. 光明中医, 2019, 34(7):139-141.
[12] 汤丹, 曹东敏, 黄广枭,等. 葛根的指纹图谱构建及共有特征峰四级杆-静电场轨道阱高分辨质谱分析[J]. 广东药科大学学报, 2019, 35(2):204-209.
[13] 史宁, 郭宏举, 耿帅,等. 超高效液相色谱串联四级杆飞行时间质谱快速测定天王补心片中五味子醇甲和藁本内酯含量[J]. 陕西中医, 2020, 41(2):251-253.
[14] 李遂新, 雷光焰, 马晓军,等. 蔓荆子黄素对人非小细胞肺癌细胞H322的作用及机制研究[J]. 现代肿瘤医学, 2020, 28(7):1072-1076.
[15] 姚舜,许立惟,周治来,等.脊髓型颈椎病手术疗效及影响因素分析[J].现代医院,2021,21(5):810-814.
[16] 黄子亮, 罗湘艳, 黄海珍. 羌活胜湿汤加减结合中频脉冲电疗法治疗颈型颈椎病的临床研究木[J]. 中国中医急症, 2019, 28(3):461-463,471.