应用神经内镜手术治疗基底节区脑出血的疗效观察

doi:10.3969/j.issn.1000-8535.2021.05.009

广州医药 ›› 2021, Vol. 52 ›› Issue (5): 44-47.DOI: 10.3969/j.issn.1000-8535.2021.05.009

应用神经内镜手术治疗基底节区脑出血的疗效观察

孙翔, 邓晓辉, 王晓柯

三门峡市中心医院神经外科二病区(三门峡 472000)

收稿日期:2021-03-16 出版日期:2021-09-20 发布日期:2021-11-24

Effect of neuroendoscopic surgery on basal ganglia intracerebral hemorrhage

SUN Xiang, DENG Xiaohui, WANG Xiaoke

Department of Neurosurgery, Sanmenxia Central Hospital,Sanmenxia 472000,China

Received:2021-03-16 Online:2021-09-20 Published:2021-11-24

摘要/Abstract

摘要： 目的分析基底节区脑出血患者接受神经内镜手术治疗的疗效。方法将2019年6月—2020年8月接诊且行开颅血肿清除术的33例基底节区脑出血患者作为对照组,将同期接诊且行神经内镜手术的33例基底节区脑出血患者作为观察组,对组间美国国立卫生研究院卒中量表(NIHSS)、独立功能量表(FIM)、日常生活能力(ADL)评分、手术情况、血清水通道蛋白4(AQP4)水平、脑水肿体积、并发症情况展开分析。结果 (1)组间NIHSS、FIM、ADL评分在术前无明显差异,P>0.05;术后,观察组NIHSS评分更低,且FIM、ADL评分更高,P<0.05;(2)观察组骨窗大小(2.53±0.66)cm、切口长度(4.22±0.67)cm、术中失血量(47.58±11.25)mL、手术用时(1.58±0.42)h均少于对照组(10.88±1.13)cm、(11.84±2.31)cm、(149.83±33.76)mL、(2.99±0.63)h,且血肿清除率(88.84±9.62)%大于对照组(75.31±7.24)%,P<0.05;(3)观察组术后1周、术后2周、术后1个月时的AQP4水平、脑水肿体积均小于对照组,P<0.05;(4)观察组发生1例并发症(3.03%),对照组发生7例并发症(21.21%),P<0.05。结论对基底节区脑出血患者进行神经内镜手术治疗,手术创伤小,可以降低AQP4水平,减少脑水肿体积及并发症,提高生活能力,值得推广。

关键词: 神经内镜手术, 基底节区脑出血, 疗效

Abstract: Objective To analyze the curative effect of neuroendoscopic surgery in patients with basal ganglia intracerebral hemorrhage. Methods From June 2019 to August 2020, 33 patients with basal ganglia intracerebral hemorrhage who received craniotomy and hematoma clearance were selected as the control group, and 33 patients with basal ganglia intracerebral hemorrhage who received neuroendoscopic surgery at the same period were selected as the observation group. NIHSS,FIM and ADL scores,details of the surgery, levels of AQP4, brain edema volume and complications were analyzed. Results (1) There were no significant differences in NIHSS, FIM and ADL scores between the two groups before operation, P＞0.05; after operation, NIHSS score of the observation group was lower, and FIM and ADL scores were higher, P＜0.05. (2) Bone window size of the observation group was (2.53±0.66) cm, incision length was (4.22±0.67) cm, intraoperative blood loss was (47.58±11.25) mL, and operation time was (1.58±0.42) h, which were less than those of the control group [(10.88±1.13) cm and (11.84±2.31) cm, (149.83±33.76) mL, (2.99±0.63) h], and the hematoma clearance rate (88.84±9.62)% was higher than that of the control group (75.31±7.24)%, P＜0.05. (3) The AQP4 level and brain edema volume of the observation group 1 week, 2 weeks and 1 month after operation were lower than those of the control group, P＜0.05. (4) There was one complication (3.03%) in the observation group and seven complications (21.21%) in the control group,P<0.05. Conclusion Neuroendoscopic surgery for patients with basal ganglia cerebral hemorrhage can reduce the level of AQP4, the volume of brain edema and complications, and improve the ability of life, which is worthy of promotion.

Key words: neuroendoscopic surgery, basal ganglia hemorrhage, curative effect

孙翔, 邓晓辉, 王晓柯. 应用神经内镜手术治疗基底节区脑出血的疗效观察[J]. 广州医药, 2021, 52(5): 44-47.

SUN Xiang, DENG Xiaohui, WANG Xiaoke. Effect of neuroendoscopic surgery on basal ganglia intracerebral hemorrhage[J]. Guangzhou Medical Journal, 2021, 52(5): 44-47.

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应用神经内镜手术治疗基底节区脑出血的疗效观察

Effect of neuroendoscopic surgery on basal ganglia intracerebral hemorrhage

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