不同类型脑梗死患者睡眠结构及其与抑郁的相关性研究

doi:10.3969/j.issn.1000-8535.2017.02.016

摘要/Abstract

摘要： 目的分析研究不同类型脑梗死患者睡眠结构及其与抑郁的相关性,为脑梗死患者睡眠障碍及抑郁的治疗提供新的思路及理论支持。方法抽取我院2012年4月—2015年5月接收的124例脑梗死患者进行分组研究,根据脑梗死不同发生部位将患者分为四组,分别为小脑梗死组30例、皮层梗死组33例、脑干梗死组29例及皮层下梗死组32例,对比观察四组患者睡眠结构及睡眠参数和睡眠障碍、HAMD评分的相关性。结果四组患者睡眠结构相比存在明显差异,脑干梗死组和皮层下梗死组觉醒时间远多于小脑梗死组和皮层梗死组,小脑梗死组NREM 1+2期、NREM期明显短于皮层梗死组、脑干梗死组及皮层下梗死组,小脑梗死组REM期、NREM 3+4期明显大于皮层梗死组、脑干梗死组及皮层下梗死组,各项数据对比差异均有统计学意义(P＜0.05);HAMD评分、PSQI评分和NREM1+2期、觉醒指数呈正相关关系(P＜0.05,r＞0);与REM期和NREM 3+4期呈负相关关系(P＜0.05,r＜0)。结论皮层下梗死睡眠结构紊乱发生率更高,并且睡眠结构的变化和脑梗死后抑郁评分、睡眠障碍评分具有一定关系。

关键词: 不同类型脑梗死, 睡眠结构, 抑郁

Abstract: Objective To study the correlation between sleep structure and depression in patients with different types of cerebral infarction,to provide new ideas and theoretical support for the treatment of sleep disorders and depression in patients with cerebral infarction. Methods 124 patients with cerebral infarction in our hospital from April 2012 to May 2015 were selected. They were divided into four groups according to the different parts of the cerebral infarction, respectively, 30 cases of cerebellar infarction group, 33 cases of cortical infarction group, 29 cases of brainstem infarction group and 32 cases of subcortical infarction group. The correlation of sleep structure and sleep parameters, sleep disorder and HAMD score of the four groups were observed and compared. Results There was a significant difference in sleep structure between the four groups. Brainstem infarction group and subcortical infarction group awakening time was far more than that of cerebellar infarction group and cortex infarction group.Cerebellar infarction group NREM 1+2, NREM period was significantly shorter in cortical infarction, brain stem infarction group and subcortical infarction group. Cerebellar infarction group of REM and NREM stage 3+4 were significantly greater than that of cortical infarction death group, brain stem infarction group and cerebral cortex infarction group. The differences were statistically significant(P<0.05);HAMD score, PSQI score and NREM1+2 period, arousal index was positively correlated (P<0.05, r> 0); And REM phase and 3+4 NREM phase was negatively correlated (P<0.05, r< 0). Conclusion Subcortical infarction sleep structure disorder incidence is higher, and the sleep structure changes and infarction depression score, sleep disorder score has a certain relationship.

Key words: Different types of cerebral infarction, Sleep architecture, Depression

黄耀忠, 李明海, 曾祥富. 不同类型脑梗死患者睡眠结构及其与抑郁的相关性研究[J]. 广州医药, 2017, 48(2): 58-60.

HUANG Yaozhong, LI Minghai, ZENG Xiangfu. Structure and correlation of different types of sleep in patients with cerebral infarction and depression[J]. Guangzhou Medical Journal, 2017, 48(2): 58-60.

[1]	樊建凤, 罗碧, 李志杰. 颈内动脉超声联合经颅多普勒对产后抑郁症患者的评价研究[J]. 广州医药, 2021, 52(4): 60-64.
[2]	陈丽萍, 韩棉梅, 傅思媚. 电针联合重复经颅磁刺激治疗脑卒中后抑郁伴失眠的临床研究[J]. 广州医药, 2021, 52(2): 6-10.
[3]	古智文, 黄雄, 薛丹. 电针联合草酸艾司西酞普兰治疗对抑郁障碍患者抑郁状态的影响[J]. 广州医药, 2021, 52(1): 12-17.
[4]	陈丽萍, 傅思媚, 古智文, 潘集阳. 高频重复经颅磁刺激治疗卒中后抑郁伴失眠的临床研究[J]. 广州医药, 2020, 51(6): 28-32.
[5]	陈丽萍, 骆春柳, 潘集阳. 综合医院护士的日间过度嗜睡及其影响因素的研究[J]. 广州医药, 2020, 51(4): 104-109.
[6]	符白玲, 邓永芳, 冯少霞, 范云. 先兆早产孕妇抑郁与唾液皮质醇浓度的相关性研究[J]. 广州医药, 2018, 49(5): 44-47.
[7]	郭彦杨, 赖志娜. 米氮平联合文拉法辛对难治性抑郁症患者认知功能及生活质量影响的观察[J]. 广州医药, 2018, 49(5): 57-60.
[8]	郑翠环, 李婷, 张少珍, 魏彩红, 黄明生. 护理干预在慢性阻塞性肺疾病患者中的效果[J]. 广州医药, 2018, 49(4): 47-50.
[9]	胡丽婵, 郭艺, 孙祺章, 余国汉, 黄月玲, 戴丽军, 党亚梅, 黄雄, 陈盛强, 黄海樱. Fmr1基因敲除小鼠悬尾实验的观察[J]. 广州医药, 2016, 47(4): 9-11.
[10]	林宇明, 陈盛强, 王焕霞. 产后抑郁与Foxp3基因位点924(rs2232365)多态性的相关性探讨[J]. 广州医药, 2016, 47(3): 1-3.
[11]	徐利敏, 潘小平, 李雪蓉, 欧阳樱君, 何方红, 郭爱华. 广州综合医院内分泌科门诊抑郁焦虑障碍调查[J]. 广州医药, 2016, 47(2): 69-71.
[12]	陈健华, 葛鑫宇, 黄俊东, 伍远菲, 朱志敏. 逍遥散治疗首发抑郁症的疗效与5-羟色胺2A受体基因多态性的关联研究[J]. 广州医药, 2016, 47(1): 81-82.
[13]	古智文, 潘小平, 张璐璐, 徐利敏, 陈丽萍, 李雪蓉, 曾贤威, 谢韫诗, 梁国强. 抑郁障碍患者血清IL-2和TNF-α水平与认知功能的相关性研究[J]. 广州医药, 2015, 46(4): 58-59.

不同类型脑梗死患者睡眠结构及其与抑郁的相关性研究

Structure and correlation of different types of sleep in patients with cerebral infarction and depression

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 13

编辑推荐

Metrics

本文评价