产后抑郁与Foxp3基因位点924(rs2232365)多态性的相关性探讨

doi:10.3969/j.issn.1000-8535.2016.03.001

广州医药 ›› 2016, Vol. 47 ›› Issue (3): 1-3.DOI: 10.3969/j.issn.1000-8535.2016.03.001

• 论著 • 下一篇

产后抑郁与Foxp3基因位点924(rs2232365)多态性的相关性探讨

林宇明¹, 陈盛强², 王焕霞¹

1 广州市越秀区光塔街社区卫生服务中心(广州 510120)
2 广州医科大学附属第二医院(广州 510260)

收稿日期:2015-09-24 出版日期:2016-05-20 发布日期:2021-11-30
通讯作者: 林宇明,E-mail: gzlinyuming123@163.com
基金资助:
广东省人口和计划生育委员会科研项目(20132054)

Discussion of the correlation between postpartum depression and Foxp3 Locus 924(rs2232365) polymorphism

Lin Yuming, Wang Huanxia, Chen Shengqiang

Lin Yuming, Wang Huanxia. Guangta Street Central Community Health Service of Yuexiu Region, Guangzhou 510120, China
Chen Shengqiang. The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China

Received:2015-09-24 Online:2016-05-20 Published:2021-11-30

摘要/Abstract

摘要： 目的探讨Foxp3-924(rs2232365)基因位点多态性与产后抑郁的相关性。方法选取211例在越秀区光塔街社区卫生服务中心分娩的产妇进行回访研究,所有产妇均经PCR-SSP技术对Foxp3-924(rs2232365)基因位点分型。结果对比产后抑郁组与对照组产妇Foxp3-924各种基因型频率,结果显示均无差异(P>0.05)。结论产后抑郁和Foxp3-924(rs2232365)位点基因多态性无较大关联。

关键词: 产后抑郁, 基因位点, 多态性

Abstract: Objective To investigate the distribution of-924(rs2232365) genotypes and to explore the correlation between gene loci polymorphism and postpartum depression. Methods In puerpera in Yuexiu district Guangta street community health center, there were 211 cases of childbirth study visits, who were confirmed by PCR-SSP technique Foxp3-924 (rs2232365) gene locus genotyping. Results Compared postpartum depression group and control groupFoxp3-924 various genotypes, it showed no great difference (P> 0.05). Conclusion It has no greater relevance between postpartum depression and Foxp3-924 (rs2232365) polymorphism loci.

Key words: Postpartum depression, Gene locus, Polymorphism

林宇明, 陈盛强, 王焕霞. 产后抑郁与Foxp3基因位点924(rs2232365)多态性的相关性探讨[J]. 广州医药, 2016, 47(3): 1-3.

Lin Yuming, Wang Huanxia, Chen Shengqiang. Discussion of the correlation between postpartum depression and Foxp3 Locus 924(rs2232365) polymorphism[J]. Guangzhou Medical Journal, 2016, 47(3): 1-3.

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产后抑郁与Foxp3基因位点924(rs2232365)多态性的相关性探讨

Discussion of the correlation between postpartum depression and Foxp3 Locus 924(rs2232365) polymorphism

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