乙型肝炎病毒感染对妊娠期糖尿病孕妇的结局分析

来源期刊：广州医药 | 11-15 发布时间：2023-10-12 收稿时间：2025/11/13 18:30:40 阅读量：43

作者：: 赵己未,

沙晓燕,

伍金娟,

吴雪,

张国正,

关键词：: 妊娠期糖尿病慢性乙型肝炎病毒感染 B族链球菌感染妊娠结局; gestational diabetes mellitus chronic hepatitis B virus infection group B streptococcus infection pregnancy outcomes

DOI：: 10.3969/j.issn.1000-8535.2023.09.002

收稿时间：: 2023-04-23
修订日期：
接收日期：
引用总数：: 0

目的探讨慢性乙型肝炎病毒（HBV）感染对妊娠期糖尿病（GDM）孕妇的妊娠并发症、孕晚期生殖道B族链球菌（GBS）感染情况以及妊娠结局的影响。方法选取2020年1月1日—12月31日在广州市妇女儿童医疗中心定期产检、足月、单胎妊娠的GDM孕妇共583例,其中合并HBV感染者（GDM+HBV组）48例,无合并者（GDM组）535例。比较2组的妊娠期并发症、妊娠晚期（妊娠35~37周）生殖道GBS感染情况、妊娠结局以及阴道分娩者的母儿结局。结果与GDM组患者相比,GDM+HBV组患者出现妊娠期肝内胆汁淤积症、孕晚期生殖道GBS感染者比例较高,孕期出现胎盘早剥者比例较高,阴道分娩过程中出现产时发热、羊水粪染和新生儿入住NICU者比例均较高（均P<0.05）。结论与无合并慢性HBV感染的GDM患者相比,合并慢性HBV感染的GDM患者在围产期的母儿风险升高。

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