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比较不同判读标准对COPD合并OSA的诊断及其特点的影响

Effects of the different scoring criteria on the diagnosis and characteristics of COPD with OSA

来源期刊: 广州医药 | 14-17 发布时间:2022-11-30 收稿时间:2025/11/13 18:14:05 阅读量:115
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慢性阻塞性肺疾病阻塞性睡眠呼吸暂停重叠综合征睡眠呼吸暂停低通气指数美国睡眠医学会
chronic obstructive pulmonary diseaseobstructive sleep apneaoverlap syndromesleep apnea-hypopnea indexAmerican Academy of Sleep Medicine
DOI:
10.3969/j.issn.1000-8535.2022.06.003
收稿时间:
2022-01-05 
修订日期:
 
接收日期:
 
引用总数:
1  
目的 比较2012版和2007版美国睡眠医学会判读标准(AASM2012和AASM2007)对慢性阻塞性肺疾病(COPD)合并阻塞性睡眠呼吸暂停(OSA)的诊断及其睡眠和临床特点的影响。方法 分别采用AASM2007与AASM2012分析41名稳定期COPD患者的睡眠呼吸事件,比较两种判读标准对COPD患者的呼吸暂停低通气指数(AHI),合并OSA的比例的影响;再对符合AASM2012但不符合AASM2007诊断的重叠综合征患者(OS2012-2007)与仅符合AASM2007诊断的COPD患者(COPDAASM2007)的睡眠参数和临床指标进行比较。结果 对比AASM2007,AASM2012显著增加COPD的睡眠呼吸暂停低通气指数(AHI)[1.0 (1.0, 7.5) h-1 vs 11.5 (4.1, 25.1) h-1, P<0.001],及合并OSA的比例(36.6% vs 70.7%, P<0.05)。OS2012-2007与COPDAASM20072组之间的微觉醒指数与3期睡眠比例有统计学差异,但其他睡眠参数、血压及高血压患病人数均无明显差异。结论 AASM2012显著增加COPD患者AHI,及合并OSA的比例,但初步的结果提示 AASM2012下新增的OS2012-2007患者的病理损害相对少且轻。
Objective To compare the effects of the 2012 and 2007 American Academy of Sleep Medicine (AASM2012 and AASM2007) scoring criteria on the diagnosis, sleep and clinical characteristics of chronic obstructive pulmonary disease (COPD) with obstructive sleep apnea (OSA). Methods AASM2007 and AASM2012 were used to analyze the sleep respiratory events of 41 patients with stable COPD. Differences in apnea-hypopnea index (AHI) and diagnosis of OSA in COPD patients between AASM2007 and AASM2012 criteria were compared. Differences in sleep parameters and clinical indexes were compared between patients with overlap syndrome who met the AASM2012 not AASM2007 criteria (OS2012-2007) and COPD patients who only met the AASM2007 criteria (COPDAASM2007). Results Using the AASM2012 criteria, the number of AHI [1.0 (1.0, 7.5) h-1 vs 11.5 (4.1, 25.1) h-1, P<0.001] and the proportion complicated with OSA (36.6% vs 70.7%, P<0.05) significantly increased compared to the AASM2007 criteria. There was a significant difference between OS2012-2007 and COPDAASM2007 in arousal index and third stage of sleep, but no significant difference in other sleep parameters, blood pressure and the number of patients with hypertension. Conclusions Using AASM2012 significantly increased AHI and the proportion complicated with OSA in COPD patients, but the preliminary results demonstrated that pathological damages of OS2012-2007 were relatively mild.
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