不明原因的自发流产与精子DNA损失的关系

来源期刊：广州医药 | 54-57 发布时间：2021-12-17 收稿时间：2025/11/13 17:33:58 阅读量：28

作者：: 刘成军,

涂艳琴,

王蔼明,

商微,

王伟周,

李敏,

沈玉良,

关键词：: 不明原因自发流产精子DNA损伤一次 DFI; Unexplained spontaneous abortion Sperm DNA damage Once DNA fragmentation index

DOI：: 10.3969/j.issn.1000-8535.2019.02.014

收稿时间：: 2019-01-10
修订日期：
接收日期：
引用总数：: 0

目的探讨一次不明原因流产与精子DNA损伤的关系。方法收集有一次不明原因流产史的患者作为实验组,同时以有正常妊娠史的患者为对照组,分别比较两组男方年龄、精子密度、精子活力、精液量和精子DNA断裂指数有无差异。以SPSS 16.0为统计软件,进行独立样本的t检验。结果两组的精液量、精子密度及活力均无差异,实验组男方年龄小于对照组(P<0.05),但实验组的DFI要高于对照组(P<0.01)。结论本研究对照组年龄高于实验组,而DFI正好相反。这说明不明原因的自发流产与男方精子DFI密切相关,随着DFI的增加,流产风险增加。

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