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良性前列腺增生并急性尿潴留患者血清肌酐、PSA及其膀胱功能的相关性研究

Relevant research of serum creatinine, PSA and bladder function in benign prostatic hyperplasia combined acute uroschesis cases

来源期刊: 广州医药 | 64-66 发布时间:2021-11-30 收稿时间:2025/11/13 17:06:30 阅读量:7
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PSA前列腺增生急性尿潴留逼尿肌收缩力肌酐
DOI:
10.3969/j.issn.1000-8535.2016.01.023
收稿时间:
2015-09-24 
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目的 探讨良性前列腺增生(BPH)并急性尿潴留(AUR)后血清肌酐、前列腺特异抗原(PSA)及其膀胱尿道功能的相关性及其临床意义。方法 对随机选择的36例已留置尿管48h以上的BPH并AUR患者进行尿流动力学检查,且同日行血清肌酐、PSA检测并分为两组:DI(逼尿肌不稳定)组(22例)和无DI组(14例),分析血清肌酐、PSA与膀胱功能各因素的相关性。结果 36例患者中逼尿肌收缩力很弱(VW)占10例,其游离PSA(fPSA)均<1.0 ng/mL,DI组中血清肌酐与膀胱顺应性、总PSA(tPSA)有相关性(r分别为0.406、-0.340,P值分别<0.01、0.05);DI幅度与膀胱顺应性、逼尿肌收缩力、tPSA有相关性(r分别为-0.309、0.677、0.304,P值分别<0.05、0.01、0.05);DI组与无DI组的fPSA与逼尿肌收缩力均有相关性(r分别为0.375、0.464,P值均<0.05)。DI组血清肌酐与fPSA、DI幅度、逼尿肌收缩力无相关性(r分别为-0.282、-0.301、-0.184,P值均>0.05);无DI组tPSA与血清肌酐、膀胱顺应性、逼尿肌收缩力无相关性(r分别为0.278、0.348、0.365,P值均>0.05)。结论 BPH并AUR患者的血清fPSA越低(<1.0 ng/mL),间接反映逼尿肌收缩力受损越严重,DI影响tPSA及肌酐水平。
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