Objective To investigate the guidance of community nursing intervention in diabetes clinical care effect. Methods A retrospective analysis of the city's three neighborhood offices resident data to be analyzed, select one of the analytical value of 100 patients with diabetes clinical data analysis, according to the different methods of care patients were divided into a control group and observation group.Control implementation of routine care group, observation group of community nursing intervention guidance, care and effect between the two groups. Results Body mass index in the experimental group (22.9±2.48) kg/m², FBG indicators (7.24±1.68) mmol/L, 2hBG indicators (9.72±2.14) mmol/L, HbALc indicators (7.26±1.08)%, significantly were lower than the control group (P<0.05); the experimental group, 96% of a reasonable diet, 98% had a regular life, 92% of patients can do exercise regularly, 94% of patients were able to self-monitoring disease.It was significantly higher (P<0.05). Conclusion Diabetic patients in community care and guidance, common sense, risk factors, lack of awareness of the issue of prevention of complications is the point of care supervise, and also one of the main problems exist. It should enhance self-management of diabetes, psychological care, diet therapy, exercise regimen, regular medication and other aspects of nursing intervention guidance. It should be increasing community awareness of prevention, improve supervision and guidance role.