目的 探究磁共振成像三维快速自旋回波序列（CUBE）序列在眼眶肿瘤及肿瘤样病变中的诊断价值。方法 选取2023年5月—2025年6月郑州市第二人民医院收治的眼眶肿瘤及肿瘤样病变患者89例为研究对象，依据病理诊断结果分为眼眶肿瘤组（43例）及肿瘤样病变组（46例）。分别采用病理检查及磁共振成像CUBE序列对研究对象进行检测。比较眼眶肿瘤组与肿瘤样病变组的资料。采用Kappa检验比较病理金标准与磁共振成像CUBE序列鉴别诊断的一致性。采用2×2列联表分析磁共振成像CUBE鉴别眼眶肿瘤及肿瘤样病变的诊断效能。结果 病理鉴别诊断结果与磁共振成像CUBE序列结果比较，差异无统计学意义（P＞0.05）。眼眶肿瘤组与肿瘤样病变组的资料比较，差异无统计学意义（P＞0.05）。Kappa检验发现，磁共振成像CUBE序列鉴别眼眶肿瘤与肿瘤样病变与病理金标准比较的Kappa值为0.820，一致性较高（P＜0.05）。磁共振成像CUBE序列鉴别眼眶肿瘤及肿瘤样病变的灵敏度为88.37%，特异度为93.48%，准确度为91.01%，误诊率为6.52%，漏诊率为11.63%，约登指数为81.85%，阳性预测概率为92.68%，阴性预测概率为89.58%。结论 磁共振成像CUBE序列鉴别诊断成人眼眶肿瘤及肿瘤样病变与病理诊断结果的一致性较高。

     Objective To investigate the diagnostic value of the three-dimensional fast spin echo sequence（CUBE）in magnetic resonance imaging for orbital tumors and tumor-like lesions．Methods From May 2023 to June 2025，89 patients with orbital tumors and tumor like lesions were included as the study subjects．Based on pathological diagnosis results，they were separated into orbital tumor group（43 cases）and tumor like lesion group（46 cases）．The pathological examination and magnetic resonance imaging CUBE sequence were used to scan the study subjects．The data were compared between the orbital tumor group and the tumor like lesion group．Kappa test was used to compare the consistency of differential diagnosis between pathological gold standard and magnetic resonance imaging CUBE sequence．A 2×2 contingency table was uesd to analyze the diagnostic performance of magnetic resonance imaging CUBE in differentiating orbital tumors and tumor-like lesions．Results The difference between the pathological differential diagnosis results and the magnetic resonance imaging CUBE sequence was not statistically significant（P＞0.05）．The data comparison between the orbital tumor group and the tumor like lesion group showed no statistical difference（P＞0.05）．The Kappa test found that the Kappa value of 0.820 for differentiating orbital tumors from tumor like lesions using the magnetic resonance imaging CUBE sequence compared to the pathological gold standard was highly consistent（P＜0.05）．The sensitivity，specificity，accuracy，misdiagnosis rate，missed diagnosis rate，Youden index，positive predictive probability，and negative predictive probability of magnetic resonance imaging CUBE sequence in differentiating orbital tumors and tumor like lesions were 88.37%，93.48%，91.01%，6.52%，11.63%，81.85%，92.68% and 89.58%，respectively．Conclusions The magnetic resonance imaging CUBE sequence has a high consistency with pathological diagnosis results in the differential diagnosis of orbital tumors and tumor like lesions．