目的 应用 Python语言对《圣济总录》中腰痛病篇中的中药进行用药规律分析,提取腰痛病治疗方法及用药特色指导临床腰痛病治疗思路。方法 运用 Python语言中的语言提取对《圣济总录》中腰痛篇章中的所有中药方剂识别,提取方剂组成,统计并分析方剂中中药的规律并将其结果可视化呈现。结果 最终共纳入62首方剂,包含药物86味。其中使用频次≥7次、频率≥1.6%的药物共20味,频次频率最高的为桂枝;所用中药四气以温性为主,占56.74%;五味以辛、甘、苦为主,共约占90%,归经以肝肾经为主;药物功效以补虚类为主,占27.13%;关联规则分析显示提升度最高的组合为麻黄-独活,置信度最高的组合为巴戟天-牛膝、牵牛子-牛膝,支持度最高的组合为川芎-当归、川芎-杜仲;通过聚类分析得到3个聚类结果。结论 《圣济总录》治疗腰痛病方面善用通法和补法,强调活血通络,补益肝肾,尤擅长治疗肝肾亏虚或风寒所客等腰痛病证。

Objective Python language was used to analyze the rules of traditional Chinese medicine in the chapter of low back pain in Shengji Zonglu,and to extract the treatment methods and medication characteristics of low back pain to guide the clinical treatment of low back pain．Methods The language extraction in Python language was used to identify all the Chinese medicine prescriptions in the chapter of low back pain in Shengji Zonglu,extract the composition of the prescription,and analyze the rules of Chinese medicine in the prescription to visually present the results．Results A total of 62 prescriptions were included,including 86 drugs．Among them,with there were 20 kinds of drugs,the frequency of use ≥7 times,the frequency ≥1.6%,and cmnamomi Mmulus highest frequency．Four gas used in traditional Chinese medicine is given priority to with warm,accounted for 56.74%．The five flavors were mainly pungent,sweet and bitter,accounting for about 90%,and the liver and kidney meridians were the main meridians．The drug efficacy was mainly deficiency tonic,accounting for 27.13%．The association rule analysis showed that the combination with the highest improvement was Ephedrae Herba- Angelicae Pubescentis Radix,the combination with the highest confidence was Morindae Officinalis Radix- Achyranthis Bidentatae Radix,Pharbitidis Semen- Achyranthis Bidentatae Radix．and the combination with the highest support was Chuanxiong Rhizoma- Angelicae Sinensis Radix,Chuanxiong Rhizoma- Eucommiae Cortex．Three clustering result is obtained by cluster analysis．Conclusions In the treatment of low back pain,Shengji Zonglu is good at using both blocking methods and reinforcing methods,emphasizing circulating blood and unblocking meridians supplementing liver and kidney,especially in the treatment of low back pain syndrome caused by liver and kidney deficiency or wind and cold．

      目的   应用 Python语言对《圣济总录》中腰痛病篇中的中药进行用药规律分析，提取腰痛病治疗方法及用药特色指导临床腰痛病治疗思路。方法   运用 Python语言中的语言提取对《圣济总录》中腰痛篇章中的所有中药方剂识别，提取方剂组成，统计并分析方剂中中药的规律并将其结果可视化呈现。结果   最终共纳入62首方剂，包含药物86味。其中使用频次≥7次、频率≥1.6%的药物共20味，频次频率最高的为桂枝；所用中药四气以温性为主，占56.74%；五味以辛、甘、苦为主，共约占90%，归经以肝肾经为主；药物功效以补虚类为主，占27.13%；关联规则分析显示提升度最高的组合为麻黄-独活，置信度最高的组合为巴戟天-牛膝、牵牛子-牛膝，支持度最高的组合为川芎-当归、川芎-杜仲；通过聚类分析得到3个聚类结果。结论   《圣济总录》治疗腰痛病方面善用通法和补法，强调活血通络，补益肝肾，尤擅长治疗肝肾亏虚或风寒所客等腰痛病证。

       Objective Python language was used to analyze the rules of traditional Chinese medicine in the chapter of low back pain in Shengji Zonglu，and to extract the treatment methods and medication characteristics of low back pain to guide the clinical treatment of low back pain．Methods The language extraction in Python language was used to identify all the Chinese medicine prescriptions in the chapter of low back pain in Shengji Zonglu，extract the composition of the prescription，and analyze the rules of Chinese medicine in the prescription to visually present the results．Results A total of 62 prescriptions were included，including 86 drugs．Among them，with there were 20 kinds of drugs，the frequency of use ≥7 times，the frequency ≥1.6%，and cmnamomi Mmulus highest frequency．Four gas used in traditional Chinese medicine is given priority to with warm，accounted for 56.74%．The five flavors were mainly pungent，sweet and bitter，accounting for about 90%，and the liver and kidney meridians were the main meridians．The drug efficacy was mainly deficiency tonic，accounting for 27.13%．The association  rule analysis showed that the combination with the highest improvement was Ephedrae Herba- Angelicae Pubescentis Radix，the combination with the highest confidence was Morindae Officinalis Radix- Achyranthis Bidentatae Radix，Pharbitidis Semen- Achyranthis Bidentatae Radix．and the combination with the highest support was Chuanxiong Rhizoma- Angelicae Sinensis Radix，Chuanxiong Rhizoma- Eucommiae Cortex．Three clustering result is obtained by cluster analysis．Conclusions In the treatment of low back pain，Shengji Zonglu is good at using both blocking methods and reinforcing methods，emphasizing circulating blood and unblocking meridians supplementing liver and kidney，especially in the treatment of low back pain syndrome caused by liver and kidney deficiency or wind and cold．