目的 分析院际转运紫绀型先天性心脏病患儿中的流行病学特征,评价院际转运在患儿救治过程中的作用及效果。方法 回顾性分析2016年1月—2019年12月我院院际转运的145例紫绀型先天性心脏病患儿的性别、年龄、体质量、生命体征、转运期间检测指标、支持治疗等资料。结果 145例紫绀型先天性心脏病男105例,女40例,73.1%(106/145)的转诊患儿是新生儿,59.3%(86/145)的转诊患儿来自三级医院,55.9%(81/145)的转诊患儿转诊距离在200 km以上,仅有10.3%(15/145)的转诊患儿转诊距离在50 km以内。转诊过程中44.1%(64/145)的患儿给予呼吸机辅助通气,33.1%(48/145)的患儿给予吸氧处理,仅22.1%(32/145)的患儿无需呼吸支持,所有患儿安全转运到接诊医院,入院后138例接受外科手术治疗手术康复,7例放弃治疗。结论 安全、有效的院际转运紫绀型先天性心脏病是救治的关键环节,为紫绀型先天性心脏病的救治提供前提。

Objective To analyzed the epidemiological characteristics of interhospital transport of cyanotic congenital heart disease in children and evaluate the effect of interhospital transport on treatment. Methods 145 children with cyanotic congenital heart disease from January 2016 to December 2019 transported in our hospital were analyzed retrospectively. Epidemiological data such as sex, age, weight, vital signs, detection indexes during transport and supportive treatment were collected. Results Among 145 children with cyanotic type of congenital heart disease there were 105 male, 40 female. 73.1% (106/145) children were newborn, 59.3% (86/145) children were from tertiary hospitals, 55.9% (81/145) children were transported over 200 km, only 10.3% (15/145) children were within 50 km. 44.1% (64/145) were given assisted ventilation during transporting, 33.1% (48/145) children were given oxygen treatment, only 22.1% (32/145) of the children did not need respiratory support. All children were transferred to the receiving hospital successfully. After admission, 138 of them received surgical treatment successfully, and 7 of them gave up treatment. Conclusion Safe and effective interhospital transport is the key to treating cyanotic congenital heart disease, which provides the basis for the treatment of cyanotic congenital heart disease.

目的 了解新生儿先天性心脏病的患病情况,为制定和采取干预措施提供依据。方法 对2015年10月—2016年9月分娩的5 769名新生儿进行心脏彩超检查,根据筛查结果进行统计分析。结果 共筛查出182例新生儿先天性心脏病,患病率3.15%,先天性心脏病新生儿中女婴比例较高,差异边缘显著,早产儿比例较高,差异有统计学意义,产母年龄和正常组分布相近。先天性心脏病类型中室间隔缺损和房间隔缺损的构成比分别排第一位(48.90%)和第二位(38.46%),严重先天性心脏病仅占5.43%。结论 新生儿先心病的发病率较高,采用心脏彩超筛查可尽早发现先心病患儿,同时需做好先心病患儿的随访工作,及时进行干预。

Objective To investigate the prevalence of neonatal congenital heart diseases (CHD) and providing basis for integrating efficient interventions. Methods The color Doppler echocardiography screening were applied to 5 769 newborns from Oct 2015 to Sep 2016, and the data was collected and analyzed. Results 182 cases of neonatal CHD were detected, and the prevalence rate of neonatal CHD was 3.15%. The proportion of girls and premature infants in the newborns with CHD was significantly higher than normal newborns, but the age distribution of their mothers was similar. In the 182 CHD cases, ventricular septal defect(48.90%) and atrial septal defect(38.46%) accounted for the most, while the constituent ratio of severe CHD was only 5.43%. Conclusion The prevalence of neonatal CHD was relatively high, and the color Doppler echocardiography screening could find out neonatal CHD earlier. The follow-up examinations and interventions should be conducted in time.

目的 探讨皮罗氏序列征伴先天性心脏病的临床特点。方法 我院2011年1月—2015年12月共收治141例皮罗氏序列征的患儿,将患儿分成单纯皮罗氏序列征组、皮罗氏序列征伴腭裂组及皮罗氏序列征伴听力损伤组,对3组患儿均行心电图及彩色多普勒超声心动图检查,对检查结果进行分析。结果 141例皮罗氏序列征患儿中共检出先天性心脏病19例,总发生率为13.47%,其中单纯皮罗氏序列征组患儿先天性心脏病的发生率为12.82%,伴腭裂组和伴听力损伤组患儿先天性心脏病的发生率分别为13.56%、25%。主要的先天性心脏病为:房间隔缺损(ASD)、室间隔缺损(VSD)、动脉导管未闭(PDA)、肺动脉瓣狭窄(PS)。通过统计学分析,3组患儿先天性心脏病的发生率差异无显著性。结论 先天性心脏病在皮罗氏序列征患儿中发生率较高,心电图及彩色多普勒超声心动图检查能清楚准确地诊断各类型的先天性心脏病,可用于皮罗氏序列征患儿常规检查,做出早期诊断、治疗,可以改善患儿的预后。

Objective To explore the clinical characteristics of congenital heart diseases in patients with Pierre-Robin sequence. Methods From January 2011 to December 2015, Guangzhou Women and Children's Medical Center has treated 141 patients with Pierre-Robin sequence. They were divided into 3 groups: Pierre-Robin sequence group, Pierre-Robin sequence and cleft palate group, and Pierre-Robin sequence and hearing impairment group. Electrocardiogram and colour Doppler echocardiogram was performed in each group and the results were analysed with statistics. Results 19 patients were found to have congenital heart diseases in 141 patients, the occurrence rate was 13.47%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence was 12.82%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence and cleft palate was 13.56%. The occurrence rate of congenital heart diseases in the group with Pierre-Robin sequence and hearing impairment was 25%. Atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA),and pulmonary valve stenosis (PS) were the most common lesions. Through statistical analysis, the occurrence rate of congenital heart diseases has no significant difference among the three groups of patients. Conclusion The occurrence rate of congenital heart diseases in patients with Pierre-Robin sequence is high. Electrocardiogram and colour Doppler echocardiogram are the useful and reliable tool in diagnosing congenital heart diseases in patients with Pierre-Robin sequence.