目的 建立针对炎症性肠病患者的运动锻炼方案。方法 通过系统检索Web of Science、Embase、Cochrane Library等数据库,综合相关文献并由两名研究者独立提取信息,制定出指导患者运动锻炼的方案。检索时间从建库截至2023年9月1日。结果 共筛选出12篇文献,包括指南、专家共识、Meta分析以及RCT试验。最终总结出运动的必要性、作用、适合人群、评估及筛选、运动方式选择、监测以及限制因素等7个方面,共计37条证据。结论 这些证据为轻中度炎症性肠病患者提供了有氧运动联合抗阻运动的最佳实践依据,可指导临床实践,规范运动训练,从而延缓疾病进展。

Objective To establish an exercise program for patients with inflammatory bowel disease（IBD）．Methods A systematic search was conducted in databases such as Web of Science,Cochrane Library,and Embase,with relevant literature being comprehensively reviewed．Information was independently extracted by two researchers to develop a program guiding patients' exercise．Searching terms included both Chinese and English keywords,with the searching period covering from the inception of the databases to September 1,2023．Results A total of 12 articles were screened,including guidelines,expert consensuses,Meta-analyses,and randomized controlled trials．Ultimately,37 pieces of evidence were summarized across seven aspects：the importance of exercise,suitable populations,assessment and screening,choice of exercise modes,monitoring and limiting factors．Conclusions These evidences provide the best practice basis for aerobic and resistance exercises in patients with mild to moderate IBD,guiding clinical practice,standardizing exercise training,and thus delaying disease progression．

目的 检索和分析新生儿医用粘胶相关性皮肤损伤(MARSI)预防及管理的相关证据,并对最佳证据进行总结,为临床提供参考,以预防住院新生儿MARSI的发生。方法 利用PIPOST公式,对新生儿MARSI的预防和管理构建循证问题并进行计算机检索。检索时限为建库至2020年3月31日。由2名已接受过系统循证培训的研究者对纳入的证据文献进行独立评价,从符合标准的文献中提取证据,并由临床审查小组对证据进行FAME论证,最终总结出最佳证据。结果 最终纳入文献2篇,包括一篇专家共识和一篇系统评价,汇总了17条证据,经过FAME论证后最终总结出11条最佳证据,包括患者评估、MARSI预防和MARSI处理三个方面。结论 新生儿MARSI的发生与诸多内外因素相关,临床主要以预防为主,建议医疗机构根据实际情况制定住院新生儿MARSI的预防和管理规范,加强医护人员培训,提升新生儿照护质量。

Objective To retrieve,appraise and summarize the best evidence of the prevention of medical adhesive related skin injury(MARSI) in neonates, and provide references for clinical practice. Methods We systematically searched for evidence on prevention of neonatal MARSI. The retrieval period was from the inception of databases to March 31,2020. Two researchers independently evaluated the quality of the literature and extracted evidence. Results Two literatures were included, including an expert consensus and a systematic review. Three categories (patient evaluation, MARSI prevention and MARSI management) and totally 11 items of best evidence were summarized. Conclusion The occurrence of neonatal MARSI is related to many internal and external factors, and prevention is the most important. Medical institutions should establish principles and practice guidelines of the management of neonatal MARSI, strengthen the training of medical staffs, and improve the quality of newborn care.