Objective To explore and analyze the value of 64-slice spiral CT three-dimensional reconstruction technology in the preoperative assessment of aortic dissection(AD)intervention.Methods From July 2023 to May 2024, 96 cases of patients suspected of aortic dissection treated in our hospital were selected as the research subjects.All patients underwent 64-slice spiral CT three-dimensional reconstruction technology examination, and imaging parameters were recorded.After the 64-slice spiral CT three-dimensional reconstruction, all patients were given interventional treatment, and the results of the interventional examination were used as the “gold standard” to evaluate the value of 64-slice spiral CT three-dimensional reconstruction technology in the preoperative assessment of aortic dissection intervention.Results Among the 96 patients,64-slice spiral CT three-dimensional reconstruction combined diagnosis identified 60 cases of aortic dissection,including 32 type I, 20 type II, and 8 type III cases.volume rendering(VR), maximum intensity projection(MIP), and muhiplanar reconstrudion(MPR) identified 56, 54, and 56 cases of aortic dissection,respectively.In 96 patients, the mean aortic diameter at the lacerated level and the mean distance from the lacerated to the left subclavicular level were(3.08±0.25)cm and(4.05±0.26)cm respectively in 64-slice spiral CT three-dimensional reconstruction examination, compared with(3.05±0.36)cm and(4.06±0.14)cm in interventional examination.There was no difference in comparison(t=0.671, P=0.503; t=0.332, P=0.740).The sensitivity, specificity, and accuracy of the 64-slice spiral CT three-dimensional reconstruction combined, VR, MIP, and MPR for the diagnosis of aortic dissection were 98.33%, 93.22%, 89.83%, 94.92%, specificity were 97.30%, 97.30%, 97.30%, 100%, accuracy were 98.96%, 94.79%, 92.71%, 96.88%.Conclusions Technology of 64-slice spiral CT three-dimensional reconstruction has high sensitivity, specificity, and accuracy in the preoperative assessment of aortic dissection intervention and is worth promoting and applying clinically.